{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T21:04:21Z","timestamp":1790629461737,"version":"4.1.0"},"reference-count":44,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100013072","name":"Major Science and Technology Project of Hainan Province","doi-asserted-by":"publisher","award":["241100110300"],"award-info":[{"award-number":["241100110300"]}],"id":[{"id":"10.13039\/501100013072","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100017700","name":"Henan Provincial Science and Technology Research Project","doi-asserted-by":"publisher","award":["232102111027"],"award-info":[{"award-number":["232102111027"]}],"id":[{"id":"10.13039\/501100017700","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100019091","name":"Key Research and Development Program of Hunan Province of China","doi-asserted-by":"publisher","award":["261111320400"],"award-info":[{"award-number":["261111320400"]}],"id":[{"id":"10.13039\/501100019091","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100019091","name":"Key Research and Development Program of Hunan Province of China","doi-asserted-by":"publisher","award":["241111111700"],"award-info":[{"award-number":["241111111700"]}],"id":[{"id":"10.13039\/501100019091","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100019091","name":"Key Research and Development Program of Hunan Province of China","doi-asserted-by":"publisher","award":["241111320100"],"award-info":[{"award-number":["241111320100"]}],"id":[{"id":"10.13039\/501100019091","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Pesticide Biochemistry and Physiology"],"published-print":{"date-parts":[[2026,9]]},"DOI":"10.1016\/j.pestbp.2026.107300","type":"journal-article","created":{"date-parts":[[2026,8,9]],"date-time":"2026-08-09T05:24:46Z","timestamp":1786253086000},"page":"107300","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Overexpression of the cytochrome P450 gene CYP99A3 likely mediates mesosulfuron-methyl resistance in Lolium multiflorum from China"],"prefix":"10.1016","volume":"223","author":[{"given":"Pei","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuqing","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xueliang","family":"Tian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongliang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Runqiang","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guochang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanbing","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.pestbp.2026.107300_bb0005","doi-asserted-by":"crossref","DOI":"10.3390\/ijms232012175","article-title":"Cytochrome P450 BsCYP99A44 and BsCYP704A177 confer metabolic resistance to ALS herbicides in Beckmannia syzigachne","volume":"23","author":"Bai","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.pestbp.2026.107300_bb0010","doi-asserted-by":"crossref","first-page":"6210","DOI":"10.1002\/ps.8967","article-title":"CYP99A2 from Aegilops tauschii metabolizes pyroxsulam but not mesosulfuron-methyl, causing different natural sensitivity to two herbicides","volume":"81","author":"Bao","year":"2025","journal-title":"Pest Manag. Sci."},{"key":"10.1016\/j.pestbp.2026.107300_bb0015","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1017\/wsc.2018.50","article-title":"Multiple herbicide\u2013resistant Italian ryegrass [Lolium perenne L. spp. multiflorum(Lam.) Husnot] in California perennial crops: characterization, mechanism of resistance, and chemical management","volume":"66","author":"Brunharo","year":"2018","journal-title":"Weed Sci."},{"key":"10.1016\/j.pestbp.2026.107300_bb0020","article-title":"Dinitroaniline herbicide resistance and mechanisms in weeds","volume":"12","author":"Chen","year":"2021","journal-title":"Front. Plant Sci."},{"key":"10.1016\/j.pestbp.2026.107300_bb0025","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1002\/ps.3318","article-title":"Unravelling the genetic bases of non-target-site-based resistance (NTSR) to herbicides: a major challenge for weed science in the forthcoming decade","volume":"69","author":"D\u00e9lye","year":"2013","journal-title":"Pest Manag. Sci."},{"key":"10.1016\/j.pestbp.2026.107300_bb0030","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1111\/j.1365-3180.2011.00864.x","article-title":"Non-target-site-based resistance should be the centre of attention for herbicide resistance research: Alopecurus myosuroides as an illustration","volume":"51","author":"D\u00c9Lye","year":"2011","journal-title":"Weed Res."},{"key":"10.1016\/j.pestbp.2026.107300_bb0035","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1614\/WS-D-13-00096.1","article-title":"Molecular mechanisms of herbicide resistance","volume":"63","author":"D\u00e9lye","year":"2017","journal-title":"Weed Sci."},{"key":"10.1016\/j.pestbp.2026.107300_bb0040","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1002\/ps.6040","article-title":"CytochromeP450-mediated herbicide metabolism in plants: current understanding and prospects","volume":"77","author":"Dimaano","year":"2021","journal-title":"Pest Manag. Sci."},{"key":"10.1016\/j.pestbp.2026.107300_bb0045","doi-asserted-by":"crossref","DOI":"10.3389\/fpls.2024.1331725","article-title":"Insight into the herbicide resistance patterns in Lolium rigidum populations in Tunisian and Moroccan wheat regions","volume":"15","author":"El-Mastouri","year":"2024","journal-title":"Front. Plant Sci."},{"key":"10.1016\/j.pestbp.2026.107300_bb0050","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1111\/tpj.12514","article-title":"RNA-Seq transcriptome analysis to identify genes involved in metabolism-based diclofop resistance in Lolium rigidum","volume":"78","author":"Gaines","year":"2014","journal-title":"Plant J."},{"key":"10.1016\/j.pestbp.2026.107300_bb0055","doi-asserted-by":"crossref","first-page":"10307","DOI":"10.1074\/jbc.REV120.013572","article-title":"Mechanisms of evolved herbicide resistance","volume":"295","author":"Gaines","year":"2020","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.pestbp.2026.107300_bb0060","doi-asserted-by":"crossref","first-page":"17742","DOI":"10.1021\/acs.jafc.3c05921","article-title":"Target-site and metabolic resistance mechanisms to Penoxsulam in late watergrass (Echinochloa phyllopogon) in China","volume":"71","author":"Gao","year":"2023","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.pestbp.2026.107300_bb0065","doi-asserted-by":"crossref","DOI":"10.1016\/j.pestbp.2023.105650","article-title":"Target-site and non-target-site based resistance to clodinafop-propargyl in wild oats (Avena fatua L.)","volume":"197","author":"Han","year":"2023","journal-title":"Pestic. Biochem. Physiol."},{"key":"10.1016\/j.pestbp.2026.107300_bb0070","doi-asserted-by":"crossref","first-page":"2105","DOI":"10.1007\/s00122-020-03580-6","article-title":"Identification of a cytochrome P450 hydroxylase, CYP81E22, as a causative gene for the high sensitivity of soybean to herbicide bentazon","volume":"133","author":"Kato","year":"2020","journal-title":"Theor. Appl. Genet."},{"key":"10.1016\/j.pestbp.2026.107300_bb0075","doi-asserted-by":"crossref","DOI":"10.1016\/j.pestbp.2022.105127","article-title":"Multiple resistance to ACCase- and ALS-inhibiting herbicides in black-grass (Alopecurus myosuroides Huds.) in China","volume":"184","author":"Lan","year":"2022","journal-title":"Pestic. Biochem. Physiol."},{"key":"10.1016\/j.pestbp.2026.107300_bb0080","article-title":"Herbicide resistance status of Italian ryegrass (Lolium multiflorum lam.) and alternative herbicide options for its effective control in the Huang-Huai-Hai plain of China","volume":"12","author":"Li","year":"2022","journal-title":"Agronomy"},{"key":"10.1016\/j.pestbp.2026.107300_bb0085","doi-asserted-by":"crossref","first-page":"21829","DOI":"10.1021\/acs.jafc.5c08615","article-title":"One glutathione S-transferase gene, GSTU163, was involved in Mesosulfuron-methyl resistance in Alopecurus japonicus","volume":"73","author":"Li","year":"2025","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.pestbp.2026.107300_bb0090","doi-asserted-by":"crossref","first-page":"27115","DOI":"10.1021\/acs.jafc.5c10416","article-title":"Conjoint genome\u2013transcriptome analysis to identify the conserved ABCC3 gene involved in glyphosate resistance in Lolium spp","volume":"73","author":"Luo","year":"2025","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.pestbp.2026.107300_bb0095","doi-asserted-by":"crossref","DOI":"10.48130\/grares-0024-0026","article-title":"The evaluation of herbicide tolerance on Lolium multiflorum","volume":"4","author":"Ma","year":"2024","journal-title":"Grass Res."},{"key":"10.1016\/j.pestbp.2026.107300_bb0100","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.pestbp.2016.12.002","article-title":"Investigation of resistance levels and mechanisms to nicosulfuron conferred by non-target-site mechanisms in large crabgrass (Digitaria sanguinalis L.) from China","volume":"141","author":"Mei","year":"2017","journal-title":"Pestic. Biochem. Physiol."},{"key":"10.1016\/j.pestbp.2026.107300_bb0105","doi-asserted-by":"crossref","DOI":"10.51694\/AdvWeedSci\/2024;42:00009","article-title":"Mechanistic understanding and sustainable management of non-target site herbicide resistance in modern day agriculture","volume":"42","author":"Mucheri","year":"2024","journal-title":"Adv. Weed Sci."},{"key":"10.1016\/j.pestbp.2026.107300_bb0110","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.1104\/pp.19.00979","article-title":"Aldo-keto reductase metabolizes glyphosate and confers glyphosate resistance in Echinochloa colona","volume":"181","author":"Pan","year":"2019","journal-title":"Plant Physiol."},{"key":"10.1016\/j.pestbp.2026.107300_bb0115","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2022.128225","article-title":"CYP81A68 confers metabolic resistance to ALS and ACCase-inhibiting herbicides and its epigenetic regulation in Echinochloa crus-galli","volume":"428","author":"Pan","year":"2022","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.pestbp.2026.107300_bb0120","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1016\/j.plantsci.2010.03.007","article-title":"Complex genetic control of non-target-site-based resistance to herbicides inhibiting acetyl-coenzyme a carboxylase and acetolactate-synthase in Alopecurus myosuroides Huds","volume":"178","author":"Petit","year":"2010","journal-title":"Plant Sci."},{"key":"10.1016\/j.pestbp.2026.107300_bb0125","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1146\/annurev-arplant-042809-112119","article-title":"Evolution in action: plants resistant to herbicides","volume":"61","author":"Powles","year":"2010","journal-title":"Annu. Rev. Plant Biol."},{"key":"10.1016\/j.pestbp.2026.107300_bb0135","doi-asserted-by":"crossref","first-page":"2891","DOI":"10.1093\/jxb\/eraf114","article-title":"Function of cytochrome P450 CYP72A1182 in metabolic herbicide resistance evolution in Amaranthus palmeri populations","volume":"76","author":"Rigon","year":"2025","journal-title":"J. Exp. Bot."},{"key":"10.1016\/j.pestbp.2026.107300_bb0140","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1371\/journal.pone.0146021","article-title":"Dose-response analysis using R","volume":"10","author":"Ritz","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.pestbp.2026.107300_bb0145","doi-asserted-by":"crossref","DOI":"10.1016\/j.pestbp.2025.106385","article-title":"The Trp-574-Leu mutations together with enhanced metabolism contribute to cross-resistance to ALS inhibiting herbicides in Fimbristylis littoralis","volume":"210","author":"Shi","year":"2025","journal-title":"Pestic. Biochem. Physiol."},{"key":"10.1016\/j.pestbp.2026.107300_bb0150","doi-asserted-by":"crossref","DOI":"10.1021\/acs.jafc.3c05963","article-title":"Cytochrome P450 CYP90D5 enhances degradation of the herbicides Isoproturon and Acetochlor in Rice plants and grains","author":"Su","year":"2023","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.pestbp.2026.107300_bb0155","doi-asserted-by":"crossref","DOI":"10.3389\/fpls.2020.609209","article-title":"Non-target-site resistance in Lolium spp. globally: a review","volume":"11","author":"Suzukawa","year":"2021","journal-title":"Front. Plant Sci."},{"key":"10.1016\/j.pestbp.2026.107300_bb0160","doi-asserted-by":"crossref","first-page":"3022","DOI":"10.1093\/molbev\/msab120","article-title":"MEGA11: molecular evolutionary genetics analysis version 11","volume":"38","author":"Tamura","year":"2021","journal-title":"Mol. Biol. Evol."},{"key":"10.1016\/j.pestbp.2026.107300_bb0165","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.pestbp.2025.106355","article-title":"Overexpression of cytochrome P450 CYP71AF43 contributing resistance to fenoxaprop-P-ethyl in Alopecurus myosuroides from China","volume":"209","author":"Tian","year":"2025","journal-title":"Pestic. Biochem. Physiol."},{"key":"10.1016\/j.pestbp.2026.107300_bb0170","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1111\/tpj.16227","article-title":"Metabolic resistance to acetolactate synthase inhibitors in Beckmannia syzigachne: identification of CYP81Q32 and its transcription regulation","volume":"115","author":"Wang","year":"2023","journal-title":"Plant J."},{"key":"10.1016\/j.pestbp.2026.107300_bb0175","doi-asserted-by":"crossref","DOI":"10.3390\/biom13020394","article-title":"Promiscuity, a driver of plant cytochrome P450 evolution?","volume":"13","author":"Werck-Reichhart","year":"2023","journal-title":"Biomolecules"},{"key":"10.1016\/j.pestbp.2026.107300_bb0180","doi-asserted-by":"crossref","DOI":"10.1016\/j.cropro.2022.106068","article-title":"Target-site mutation and cytochrome P450s confer resistance to multiple herbicides in Italian ryegrass (Lolium multiflorum lam.) from China","volume":"161","author":"Wu","year":"2022","journal-title":"Crop Prot."},{"key":"10.1016\/j.pestbp.2026.107300_bb0185","first-page":"228","article-title":"Genome-wide identification and expression analysis of cytochrome P450 gene family in Macrobrachium nipponense","volume":"10","author":"Wu","year":"2025","journal-title":"Aquacult. Fish."},{"key":"10.1016\/j.pestbp.2026.107300_bb0190","doi-asserted-by":"crossref","DOI":"10.1016\/j.pestbp.2024.106263","article-title":"Effects of Pro197 resistance mutations occurring in different acetolactate synthase (ALS) isozymes on Descurainia sophia L. resistance to tribenuron-methyl","volume":"208","author":"Xu","year":"2025","journal-title":"Pestic. Biochem. Physiol."},{"key":"10.1016\/j.pestbp.2026.107300_bb0195","doi-asserted-by":"crossref","DOI":"10.1016\/j.pestbp.2022.105260","article-title":"PsbA gene over-expression and enhanced metabolism conferring resistance to atrazine in Commelina communis","volume":"188","author":"Yang","year":"2022","journal-title":"Pestic. Biochem. Physiol."},{"key":"10.1016\/j.pestbp.2026.107300_bb0200","doi-asserted-by":"crossref","first-page":"7988","DOI":"10.1021\/acs.jafc.3c00646","article-title":"Ile-1781-Leu target mutation and non-target-site mechanism confer resistance to acetyl-CoA carboxylase-inhibiting herbicides in Digitaria ciliaris var. chrysoblephara","volume":"71","author":"Yang","year":"2023","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.pestbp.2026.107300_bb0205","doi-asserted-by":"crossref","DOI":"10.1016\/j.plaphy.2024.108597","article-title":"Target-site and non-target-site resistance mechanisms confer mesosulfuron-methyl resistance in Alopecurus aequalis","volume":"210","author":"Zhan","year":"2024","journal-title":"Plant Physiol. Biochem."},{"key":"10.1016\/j.pestbp.2026.107300_bb0210","doi-asserted-by":"crossref","DOI":"10.1007\/s00299-025-03620-9","article-title":"Deciphering the dual resistance pathways to mesosulfuron-methyl in Lolium multiflorum: target-site and non-target-site insights","volume":"44","author":"Zhang","year":"2025","journal-title":"Plant Cell Rep."},{"key":"10.1016\/j.pestbp.2026.107300_bb0215","doi-asserted-by":"crossref","DOI":"10.1016\/j.plaphy.2025.109609","article-title":"Identification of metabolic enzyme genes linked to mesosulfuron-methyl resistance in Bromus japonicus","volume":"221","author":"Zhao","year":"2025","journal-title":"Plant Physiol. Biochem."},{"key":"10.1016\/j.pestbp.2026.107300_bb0220","doi-asserted-by":"crossref","first-page":"11606","DOI":"10.1021\/acs.jafc.5c01785","article-title":"First report on resistance to ALS-inhibiting herbicides in the broadleaved weed common vetch (Vicia sativa L.) and visual detection of the associated ALS resistance mutation","volume":"73","author":"Zhao","year":"2025","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.pestbp.2026.107300_bb0225","article-title":"Multiple resistance to three modes of action of herbicides in a single Italian ryegrass (Lolium multiflorum L.) population in China","volume":"13","author":"Zhu","year":"2023","journal-title":"Agronomy"}],"container-title":["Pesticide Biochemistry and Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0048357526003615?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0048357526003615?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T20:33:08Z","timestamp":1790627588000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0048357526003615"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":44,"alternative-id":["S0048357526003615"],"URL":"https:\/\/doi.org\/10.1016\/j.pestbp.2026.107300","relation":{},"ISSN":["0048-3575"],"issn-type":[{"value":"0048-3575","type":"print"}],"subject":[],"published":{"date-parts":[[2026,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Overexpression of the cytochrome P450 gene CYP99A3 likely mediates mesosulfuron-methyl resistance in Lolium multiflorum from China","name":"articletitle","label":"Article Title"},{"value":"Pesticide Biochemistry and Physiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.pestbp.2026.107300","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"107300"}}