{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T09:40:50Z","timestamp":1792748450635,"version":"4.5.0"},"reference-count":58,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2024YFD1401000"],"award-info":[{"award-number":["2024YFD1401000"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32372587"],"award-info":[{"award-number":["32372587"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Pesticide Biochemistry and Physiology"],"published-print":{"date-parts":[[2026,11]]},"DOI":"10.1016\/j.pestbp.2026.107337","type":"journal-article","created":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T23:43:17Z","timestamp":1788565397000},"page":"107337","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Two parallel pathways mediate Cry1Ac toxicity in the Asian corn borer: one dependent on ABCC2 and one requiring synergistic action of cadherin and ABCC3"],"prefix":"10.1016","volume":"224","author":[{"given":"Xuna","family":"Zhuang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yujin","family":"Yue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuqian","family":"Zhai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dandan","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Falong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuwen","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yihua","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yidong","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xingliang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.pestbp.2026.107337_bb0005","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1017\/S0007485324000919","article-title":"Global distribution and sustainable management of Asian corn borer (ACB), (Lepidoptera: Crambidae): recent advancement and future prospects","volume":"115","author":"Abbas","year":"2025","journal-title":"Bull. Entomol. Res."},{"key":"10.1016\/j.pestbp.2026.107337_bb0010","doi-asserted-by":"crossref","first-page":"E1591","DOI":"10.1073\/pnas.1120698109","article-title":"Single amino acid mutation in an ATP-binding cassette transporter gene causes resistance to Bt toxin Cry1Ab in the silkworm, Bombyx mori","volume":"109","author":"Atsumi","year":"2012","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.pestbp.2026.107337_bb0015","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-017-09866-y","article-title":"Mechanism and DNA-based detection of field-evolved resistance to transgenic Bt corn in fall armyworm (Spodoptera frugiperda)","volume":"7","author":"Banerjee","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.pestbp.2026.107337_bb0020","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1534\/genetics.111.130971","article-title":"Parallel evolution of Bacillus thuringiensis toxin resistance in lepidoptera","volume":"189","author":"Baxter","year":"2011","journal-title":"Genetics"},{"key":"10.1016\/j.pestbp.2026.107337_bb0025","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1016\/j.ibmb.2011.02.006","article-title":"Bacillus thuringiensis: a story of a successful bioinsecticide","volume":"41","author":"Bravo","year":"2011","journal-title":"Insect Biochem. Mol. Biol."},{"issue":"2","key":"10.1016\/j.pestbp.2026.107337_bb0030","first-page":"1","article-title":"F2 screening for rare resistance alleles of Asian corn borer, Ostrinia furnacalis Guen\u00e9e (Lepidoptera: Crambidae) in the Philippines","volume":"21","author":"Cayabyab","year":"2015","journal-title":"J. ISSAAS"},{"key":"10.1016\/j.pestbp.2026.107337_bb0035","doi-asserted-by":"crossref","first-page":"2548","DOI":"10.1603\/EC13100","article-title":"Efficacy evaluation of two transgenic maize events expressing fused proteins to CrylAb-susceptible and -resistant Ostrinia furnacalis (Lepidoptera: Crambidae)","volume":"106","author":"Chang","year":"2013","journal-title":"J. Econ. Entomol."},{"key":"10.1016\/j.pestbp.2026.107337_bb0040","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ibmb.2015.01.014","article-title":"Endogenous expression of a Bt toxin receptor in the Cry1Ac-susceptible insect cell line and its synergistic effect with cadherin on cytotoxicity of activated Cry1Ac","volume":"59","author":"Chen","year":"2015","journal-title":"Insect Biochem. Mol. Biol."},{"key":"10.1016\/j.pestbp.2026.107337_bb0045","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1007\/s11248-013-9737-0","article-title":"No effects of Bacillus thuringiensis maize on nontarget organisms in the field in southern Europe: a meta-analysis of 26 arthropod taxa","volume":"23","author":"Comas","year":"2014","journal-title":"Transgenic Res."},{"key":"10.1016\/j.pestbp.2026.107337_bb0050","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1128\/MMBR.62.3.807-813.1998","article-title":"Revision of the nomenclature for the Bacillus thuringiensis pesticidal crystal proteins","volume":"62","author":"Crickmore","year":"1998","journal-title":"Microbiol. Mol. Biol. Rev."},{"key":"10.1016\/j.pestbp.2026.107337_bb0055","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/S0168-9525(01)02237-5","article-title":"How Bacillus thuringiensis has evolved specific toxins to colonize the insect world","volume":"17","author":"De Maagd","year":"2001","journal-title":"Trends Genet."},{"key":"10.1016\/j.pestbp.2026.107337_bb0060","series-title":"Bacillus thuringiensis Cry1A.105 and Cry2Ab2 Insecticidal Proteins and the Genetic Material Necessary for their Production in Corn. Biopesticide Registration Action Document","author":"EPA","year":"2010"},{"key":"10.1016\/j.pestbp.2026.107337_bb0065","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/bs.aiip.2023.09.005","article-title":"Mechanisms and molecular genetics of insect resistance to insecticidal proteins from Bacillus thuringiensis","volume":"65","author":"Fabrick","year":"2023","journal-title":"Adv. Insect Physiol."},{"key":"10.1016\/j.pestbp.2026.107337_bb0070","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-023-35252-y","article-title":"Genetic mutations linked to field-evolved Cry1Fa-resistance in the European corn borer, Ostrinia nubilalis","volume":"13","author":"Farhan","year":"2023","journal-title":"Sci. Rep."},{"key":"10.1016\/j.pestbp.2026.107337_bb0075","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1126\/science.1060949","article-title":"Identification of a gene associated with Bt resistance in Heliothis virescens","volume":"293","author":"Gahan","year":"2001","journal-title":"Science"},{"key":"10.1016\/j.pestbp.2026.107337_bb0080","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1001248","article-title":"An ABC transporter mutation is correlated with insect resistance to Bacillus thuringiensis Cry1Ac toxin","volume":"6","author":"Gahan","year":"2010","journal-title":"PLoS Genet."},{"key":"10.1016\/j.pestbp.2026.107337_bb0085","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.jip.2018.05.004","article-title":"Analysis of cross-resistance to Vip3 proteins in eight insect colonies, from four insect species, selected for resistance to Bacillus thuringiensis insecticidal proteins","volume":"155","author":"Gomis-Cebolla","year":"2018","journal-title":"J. Invertebr. Pathol."},{"key":"10.1016\/j.pestbp.2026.107337_bb0090","doi-asserted-by":"crossref","first-page":"1218","DOI":"10.1002\/ps.8520","article-title":"Control efficacy of Bt-Cry1Ab maize (event DBN9936) against Ostrinia furnacalis (Guen\u00e9e) in Sichuan Province, China","volume":"81","author":"He","year":"2025","journal-title":"Pest Manag. Sci."},{"key":"10.1016\/j.pestbp.2026.107337_bb0095","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2507583122","article-title":"Built-in redundant killing by Bt Cry1Ab toxin delays insect resistance","volume":"122","author":"Heckel","year":"2025","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.pestbp.2026.107337_bb0100","doi-asserted-by":"crossref","DOI":"10.1016\/j.ibmb.2020.103361","article-title":"Evaluation of five candidate receptors for three Bt toxins in the beet armyworm using CRISPR-mediated gene knockouts","volume":"121","author":"Huang","year":"2020","journal-title":"Insect Biochem. Mol. Biol."},{"key":"10.1016\/j.pestbp.2026.107337_bb0105","series-title":"Global Status of Commercialized Biotech\/GM Crops in 2019: Biotech Crops Drive Socioeconomic Development and Sustainable Environment in the New Frontier","author":"ISAAA, International Service for the Acquisition of Agri-biotech Applications (ISAAA)","year":"2019"},{"key":"10.1016\/j.pestbp.2026.107337_bb0110","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1016\/S2095-3119(19)62772-3","article-title":"Genome editing of the SfABCC2 gene confers resistance to Cry1F toxin from Bacillus thuringiensis in Spodoptera frugiperda","volume":"20","author":"Jin","year":"2021","journal-title":"J. Integr. Agric."},{"key":"10.1016\/j.pestbp.2026.107337_bb0115","doi-asserted-by":"crossref","first-page":"658","DOI":"10.3390\/toxins13090658","article-title":"Cadherin protein is involved in the action of Bacillus thuringiensis Cry1Ac toxin in Ostrinia furnacalis","volume":"13","author":"Jin","year":"2021","journal-title":"Toxins"},{"key":"10.1016\/j.pestbp.2026.107337_bb0120","doi-asserted-by":"crossref","DOI":"10.1016\/j.pestbp.2025.106721","article-title":"Differential roles of ABCC2, ABCC3, and cadherin in mediating Cry1Ac toxicity in Spodoptera exigua","volume":"216","author":"Jin","year":"2026","journal-title":"Pestic. Biochem. Physiol."},{"key":"10.1016\/j.pestbp.2026.107337_bb0125","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1146\/annurev-ento-052620-073348","article-title":"Mechanisms of resistance to insecticidal proteins from Bacillus thuringiensis","volume":"66","author":"Jurat-Fuentes","year":"2021","journal-title":"Annu. Rev. Entomol."},{"key":"10.1016\/j.pestbp.2026.107337_bb0130","first-page":"1","article-title":"Cadherin BtR175 and ATP-binding cassette transporter protein ABCC2 or ABCC3 facilitate Bacillus thuringiensis Cry1Aa intoxication in Bombyx mori","volume":"91","author":"Kim","year":"2022","journal-title":"J. Insect Biotechnol. Sericol."},{"key":"10.1016\/j.pestbp.2026.107337_bb0135","series-title":"Polo plus: A User\u2019s Guide to Probit and Logit Analysis","author":"LeOra Software","year":"2002"},{"key":"10.1016\/j.pestbp.2026.107337_bb0140","doi-asserted-by":"crossref","first-page":"4311","DOI":"10.1002\/ps.5999","article-title":"Baseline susceptibility and resistance allele frequency in Ostrinia furnacalis related to Cry1 toxins in the Huanghuaihai summer corn region of China","volume":"76","author":"Li","year":"2020","journal-title":"Pest Manag. Sci."},{"key":"10.1016\/j.pestbp.2026.107337_bb0145","doi-asserted-by":"crossref","first-page":"2218","DOI":"10.1128\/aem.63.6.2218-2223.1997","article-title":"Inheritance of resistance to the Bacillus thuringiensis toxin Cry1C in the diamondback moth","volume":"63","author":"Liu","year":"1997","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.pestbp.2026.107337_bb0150","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1008697","article-title":"Resistance to Bacillus thuringiensis Cry1Ac toxin requires mutations in two Plutella xylostella ATP-binding cassette transporter paralogs","volume":"16","author":"Liu","year":"2020","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.pestbp.2026.107337_bb0155","doi-asserted-by":"crossref","first-page":"255","DOI":"10.3390\/toxins14040255","article-title":"Baseline susceptibility and resistance allele frequency in Ostrinia furnacalis in relation to Cry1Ab toxins in China","volume":"14","author":"Liu","year":"2022","journal-title":"Toxins"},{"key":"10.1016\/j.pestbp.2026.107337_bb0160","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1038\/nature11153","article-title":"Widespread adoption of Bt cotton and insecticide decrease promotes biocontrol services","volume":"487","author":"Lu","year":"2012","journal-title":"Nature"},{"key":"10.1016\/j.pestbp.2026.107337_bb0165","doi-asserted-by":"crossref","first-page":"77","DOI":"10.3109\/07388551.2013.823595","article-title":"An overview of the last 10 years of genetically engineered crop safety research","volume":"34","author":"Nicolia","year":"2014","journal-title":"Crit. Rev. Biotechnol."},{"key":"10.1016\/j.pestbp.2026.107337_bb0170","doi-asserted-by":"crossref","first-page":"32","DOI":"10.3390\/toxins14010032","article-title":"Alteration of a Cry1A shared binding site in a Cry1Ab-selected colony of Ostrinia furnacalis","volume":"14","author":"Pinos","year":"2022","journal-title":"Toxins"},{"key":"10.1016\/j.pestbp.2026.107337_bb0175","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/j.molp.2024.03.005","article-title":"Commercial genetically modified corn and soybean are poised following pilot planting in China","volume":"17","author":"Sun","year":"2024","journal-title":"Mol. Plant"},{"key":"10.1016\/j.pestbp.2026.107337_bb0180","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1002\/ps.8402","article-title":"A Vip3Af mutant confers high resistance to broad lepidopteran insect pests","volume":"81","author":"Sun","year":"2025","journal-title":"Pest Manag. Sci."},{"key":"10.1016\/j.pestbp.2026.107337_bb0185","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2019115118","article-title":"Transgenic cotton and sterile insect releases synergize eradication of pink bollworm a century after it invaded the United States","volume":"118","author":"Tabashnik","year":"2021","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.pestbp.2026.107337_bb0190","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1093\/jee\/toad054","article-title":"Global perspectives on field-evolved resistance to transgenic Bt crops: a special collection","volume":"116","author":"Tabashnik","year":"2023","journal-title":"J. Econ. Entomol."},{"key":"10.1016\/j.pestbp.2026.107337_bb0195","doi-asserted-by":"crossref","first-page":"1782","DOI":"10.1111\/febs.12200","article-title":"The ATP-binding cassette transporter subfamily C member 2 in Bombyx mori larvae is a functional receptor for Cry toxins from Bacillus thuringiensis","volume":"280","author":"Tanaka","year":"2013","journal-title":"FEBS J."},{"key":"10.1016\/j.pestbp.2026.107337_bb0200","doi-asserted-by":"crossref","first-page":"4474","DOI":"10.1111\/febs.13952","article-title":"Functional characterization of Bacillus thuringiensis cry toxin receptors explains resistance in insects","volume":"283","author":"Tanaka","year":"2016","journal-title":"FEBS J."},{"key":"10.1016\/j.pestbp.2026.107337_bb0205","doi-asserted-by":"crossref","first-page":"2626","DOI":"10.1038\/s41598-018-21012-w","article-title":"Isolating, characterising and identifying a Cry1Ac resistance mutation in field populations of Helicoverpa punctigera","volume":"8","author":"Walsh","year":"2018","journal-title":"Sci. Rep."},{"key":"10.1016\/j.pestbp.2026.107337_bb0210","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.ibmb.2016.06.008","article-title":"Functional validation of cadherin as a receptor of Bt toxin Cry1Ac in Helicoverpa armigera utilizing the CRISPR\/Cas9 system","volume":"76","author":"Wang","year":"2016","journal-title":"Insect Biochem. Mol. Biol."},{"key":"10.1016\/j.pestbp.2026.107337_bb0215","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.ibmb.2018.09.013","article-title":"Bacillus thuringiensis Cry1A toxins exert toxicity by multiple pathways in insects","volume":"102","author":"Wang","year":"2018","journal-title":"Insect Biochem. Mol. Biol."},{"key":"10.1016\/j.pestbp.2026.107337_bb0220","doi-asserted-by":"crossref","first-page":"461","DOI":"10.3390\/toxins11080461","article-title":"Evolution of Asian corn borer resistance to Bt toxins used singly or in pairs","volume":"11","author":"Wang","year":"2019","journal-title":"Toxins"},{"key":"10.1016\/j.pestbp.2026.107337_bb0225","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1008427","article-title":"Functional redundancy of two ABC transporter proteins in mediating toxicity of Bacillus thuringiensis to cotton bollworm","volume":"16","author":"Wang","year":"2020","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.pestbp.2026.107337_bb0230","doi-asserted-by":"crossref","first-page":"246","DOI":"10.3390\/toxins12040246","article-title":"CRISPR-mediated knockout of the ABCC2 gene in Ostrinia furnacalis confers high-level resistance to the Bacillus thuringiensis Cry1Fa toxin","volume":"12","author":"Wang","year":"2020","journal-title":"Toxins"},{"key":"10.1016\/j.pestbp.2026.107337_bb0235","doi-asserted-by":"crossref","DOI":"10.1016\/j.ibmb.2021.103649","article-title":"ATP-binding cassette transporter subfamily C members 2, 3 and cadherin protein are susceptibility-determining factors in Bombyx mori for multiple Bacillus thuringiensis Cry1 toxins","volume":"139","author":"Wang","year":"2021","journal-title":"Insect Biochem. Mol. Biol."},{"key":"10.1016\/j.pestbp.2026.107337_bb0240","doi-asserted-by":"crossref","first-page":"137","DOI":"10.3390\/toxins15020137","article-title":"Seven years of monitoring susceptibility to Cry1Ab and Cry1F in Asian corn borer","volume":"15","author":"Wang","year":"2023","journal-title":"Toxins"},{"key":"10.1016\/j.pestbp.2026.107337_bb0245","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2025.143392","article-title":"Two pathways mediate toxicity of Cry1Ac in Mythimna separata: one is ABCC2-dependent and the other involves ABCC3-CAD interaction","volume":"310","author":"Wang","year":"2025","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.pestbp.2026.107337_bb0250","article-title":"Functional redundancy in the toxic pathway of Bt protein Cry1Ab, but not Cry1Fa, against the Asian corn borer","volume":"122","author":"Wang","year":"2025","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.pestbp.2026.107337_bb0255","doi-asserted-by":"crossref","first-page":"6184","DOI":"10.1038\/srep06184","article-title":"Mis-splicing of the ABCC2 gene linked with Bt toxin resistance in Helicoverpa armigera","volume":"4","author":"Xiao","year":"2014","journal-title":"Sci. Rep."},{"key":"10.1016\/j.pestbp.2026.107337_bb0260","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1128\/AEM.71.2.948-954.2005","article-title":"Disruption of a cadherin gene associated with resistance to Cry1Ac \u03b4-endotoxin of Bacillus thuringiensis in Helicoverpa armigera","volume":"71","author":"Xu","year":"2005","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.pestbp.2026.107337_bb0265","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1111\/j.1439-0418.2010.01517.x","article-title":"Cross-resistance of Cry1Ab-selected Asian corn borer to other Cry toxins","volume":"134","author":"Xu","year":"2010","journal-title":"J. Appl. Entomol."},{"key":"10.1016\/j.pestbp.2026.107337_bb0270","doi-asserted-by":"crossref","first-page":"2694","DOI":"10.3390\/toxins6092694","article-title":"Inheritance patterns, dominance and cross-resistance of Cry1Ab- and Cry1Ac-selected Ostrinia furnacalis (Guen\u00e9e)","volume":"6","author":"Zhang","year":"2014","journal-title":"Toxins"},{"key":"10.1016\/j.pestbp.2026.107337_bb0275","doi-asserted-by":"crossref","DOI":"10.1016\/j.ibmb.2021.103635","article-title":"Synergistic resistance of Helicoverpa armigera to Bt toxins linked to cadherin and ABC transporters mutations","volume":"137","author":"Zhang","year":"2021","journal-title":"Insect Biochem. Mol. Biol."},{"key":"10.1016\/j.pestbp.2026.107337_bb0280","doi-asserted-by":"crossref","DOI":"10.1016\/j.pestbp.2025.106526","article-title":"Identification of SfABCC2 as the critical receptor for Cry1Fa and Cry1Ab in Spodoptera frugiperda via CRISPR-mediated gene knockouts","volume":"213","author":"Zhang","year":"2025","journal-title":"Pestic. Biochem. Physiol."},{"key":"10.1016\/j.pestbp.2026.107337_bb0285","doi-asserted-by":"crossref","first-page":"4384","DOI":"10.1002\/ps.70555","article-title":"Improved insecticidal activity of Vip3Ca protein through enhanced processing and receptor affinity","volume":"82","author":"Zhang","year":"2026","journal-title":"Pest Manag. Sci."},{"key":"10.1016\/j.pestbp.2026.107337_bb0290","doi-asserted-by":"crossref","first-page":"9","DOI":"10.3390\/toxins13010009","article-title":"Independent and synergistic effects of knocking out two ABC transporter genes on resistance to Bacillus thuringiensis toxins Cry1Ac and Cry1Fa in diamondback moth","volume":"13","author":"Zhao","year":"2021","journal-title":"Toxins"}],"container-title":["Pesticide Biochemistry and Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0048357526003986?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0048357526003986?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T08:50:08Z","timestamp":1792745408000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0048357526003986"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,11]]},"references-count":58,"alternative-id":["S0048357526003986"],"URL":"https:\/\/doi.org\/10.1016\/j.pestbp.2026.107337","relation":{},"ISSN":["0048-3575"],"issn-type":[{"value":"0048-3575","type":"print"}],"subject":[],"published":{"date-parts":[[2026,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Two parallel pathways mediate Cry1Ac toxicity in the Asian corn borer: one dependent on ABCC2 and one requiring synergistic action of cadherin and ABCC3","name":"articletitle","label":"Article Title"},{"value":"Pesticide Biochemistry and Physiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.pestbp.2026.107337","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"107337"}}