{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,2]],"date-time":"2025-08-02T14:24:49Z","timestamp":1754144689980,"version":"3.41.2"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2014,2,1]],"date-time":"2014-02-01T00:00:00Z","timestamp":1391212800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pharmacological Reports"],"published-print":{"date-parts":[[2014,2]]},"DOI":"10.1016\/j.pharep.2013.06.011","type":"journal-article","created":{"date-parts":[[2014,2,19]],"date-time":"2014-02-19T17:21:34Z","timestamp":1392830494000},"page":"165-168","source":"Crossref","is-referenced-by-count":13,"title":["Combination therapy of gamma-aminobutyric acid derivative promotes proton pump inhibitor based healing of reflux esophagitis in animal model"],"prefix":"10.1007","volume":"66","author":[{"given":"Pradeep","family":"Khinchi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sudipta","family":"Saha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shubhini A.","family":"Saraf","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gaurav","family":"Kaithwas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"10.1016\/j.pharep.2013.06.011_bib0005","series-title":"CRS handbook of methods for oxygen radical research","first-page":"283","article-title":"Catalase activity","author":"Claiborne","year":"1985"},{"key":"10.1016\/j.pharep.2013.06.011_bib0010","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1136\/gut.2004.051821","article-title":"Epidemiology of gastro-esophageal reflux disease: a systematic review","volume":"54","author":"Dent","year":"2005","journal-title":"Gut"},{"key":"10.1016\/j.pharep.2013.06.011_bib0015","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/0003-9861(59)90090-6","article-title":"Tissue sulphydryl groups","volume":"82","author":"Ellman","year":"1995","journal-title":"Anal Biochem Biophys"},{"key":"10.1016\/j.pharep.2013.06.011_bib0020","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1111\/j.1572-0241.2002.05444.x","article-title":"Reactive oxygen species: are they involved in the pathogenesis of GERD. Barrett's esophagus and the Latter's progression toward Esophageal cancer","volume":"97","author":"Farhadi","year":"2002","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.pharep.2013.06.011_bib0025","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/S1098-3597(03)90096-2","article-title":"Treatment of GERD","volume":"5","author":"Fass","year":"2003","journal-title":"Clin Cornerstone"},{"key":"10.1016\/j.pharep.2013.06.011_bib0030","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1007\/s12171-007-0027-8","article-title":"Functional heartburn, non-erosive reflux disease and reflux esophagitis are all distinct conditions: a debate","volume":"1","author":"Fry","year":"2007","journal-title":"Curr GERD Rep"},{"key":"10.1016\/j.pharep.2013.06.011_bib0035","first-page":"1311","article-title":"Management of gastroesophageal reflux","volume":"68","author":"Joel","year":"2003","journal-title":"Am Fam Physician"},{"key":"10.1016\/j.pharep.2013.06.011_bib0040","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1007\/s10787-010-0037-5","article-title":"Evaluation of antiulcer and antisecretory potential of L. usitatisimum fixed oil and possible mechanism of action","volume":"18","author":"Kaithwas","year":"2010","journal-title":"Inflammopharmacology"},{"key":"10.1016\/j.pharep.2013.06.011_bib0045","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/S0016-5085(00)70408-2","article-title":"Control of transiet lower esophagus spincture relaxations and reflux by the GABA(B) agonist baclofen in normal subjects","volume":"118","author":"Lidmus","year":"2000","journal-title":"Gastroenterology"},{"key":"10.1016\/j.pharep.2013.06.011_bib0050","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/0003-2697(79)90738-3","article-title":"Assay of lipid peroxide in animal tissues by thiobarbituric acid reaction","volume":"95","author":"Ohkawa","year":"1979","journal-title":"Anal Biochem"},{"key":"10.1016\/j.pharep.2013.06.011_bib0055","doi-asserted-by":"crossref","first-page":"1160","DOI":"10.3748\/wjg.v17.i9.1160","article-title":"Pace Fabio: GERD management according to contemporary international guidelines: a translational study","volume":"17","year":"2011","journal-title":"World J Gastroenterol"},{"key":"10.1016\/j.pharep.2013.06.011_bib0060","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1111\/j.1600-079X.2006.00359.x","article-title":"Regression of gastro-esophageal reflux disease symptoms using dietary supplementation with melatonin, vitamins and amino acids: comparison with omeprazole","volume":"41","author":"Pereira","year":"2006","journal-title":"J Pineal Res"},{"key":"10.1016\/j.pharep.2013.06.011_bib0065","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.ejphar.2008.04.062","article-title":"Effect of quercetin, flavonoids and \u03b1-tocopherol, an antioxidant vitamin on experimental reflux esophagitis in rats","volume":"589","author":"Rao","year":"2008","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.pharep.2013.06.011_bib0070","first-page":"331","article-title":"Effect of Linum usitatisumum fixed oil on experimental esophagitis in rats","volume":"LXXV","author":"Renu","year":"2012","journal-title":"Acta Gastroenterol Bel"},{"key":"10.1016\/j.pharep.2013.06.011_bib0075","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1016\/j.coph.2008.09.004","article-title":"PPI: the beginning of the end or the end of the beginning?","volume":"8","author":"Scarpignato","year":"2008","journal-title":"Curr Opin Pharmacol"},{"key":"10.1016\/j.pharep.2013.06.011_bib0080","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/0003-2697(68)90092-4","article-title":"Estimation of total protein and non-protein bound sulphahydryl groups in tissue with Ellman's reagent","volume":"25","author":"Sedlak","year":"1968","journal-title":"Anal Biochem"},{"key":"10.1016\/j.pharep.2013.06.011_bib0085","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.jep.2008.01.022","article-title":"Protective effects of Terminalia arjuna against doxorubicin-induced cardiotoxicity","volume":"117","author":"Singh","year":"2008","journal-title":"J Ethnopharmacol"},{"key":"10.1016\/j.pharep.2013.06.011_bib0090","first-page":"467","article-title":"Gastric mucosal injury caused by hemorrhagic shock and reperfusion: protective role of the antioxidant glutathione","volume":"108","author":"Stein","year":"1990","journal-title":"Am J Surg"},{"key":"10.1016\/j.pharep.2013.06.011_bib0095","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1016\/j.tips.2011.02.007","article-title":"Pharmacological management of GERD: where does it stand now?","volume":"32","author":"Tiberiu","year":"2011","journal-title":"Trends Pharmacol Sci"},{"key":"10.1016\/j.pharep.2013.06.011_bib0100","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1111\/j.1365-2982.2004.00580.x","article-title":"Quantitative changes in gastric mucosal glycoproteins: effect of cholinergic agonist and vagal nerve stimulation in the rat","volume":"16","author":"Yusuf","year":"2004","journal-title":"Neurogastroenterology"}],"container-title":["Pharmacological Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1734114014000267?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1734114014000267?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,7,15]],"date-time":"2025-07-15T20:35:12Z","timestamp":1752611712000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1016\/j.pharep.2013.06.011"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,2]]},"references-count":20,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,2]]}},"alternative-id":["S1734114014000267"],"URL":"https:\/\/doi.org\/10.1016\/j.pharep.2013.06.011","relation":{},"ISSN":["1734-1140"],"issn-type":[{"type":"print","value":"1734-1140"}],"subject":[],"published":{"date-parts":[[2014,2]]}}}