{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T12:14:48Z","timestamp":1773404088036,"version":"3.50.1"},"reference-count":60,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2019,10,1]],"date-time":"2019-10-01T00:00:00Z","timestamp":1569888000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Specific University Research"},{"name":"Faculty of Medicine MU"},{"DOI":"10.13039\/501100009553","name":"Czech Health Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100009553","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001823","name":"MEYS CR","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100001823","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Pharmacological Reports"],"published-print":{"date-parts":[[2019,10]]},"DOI":"10.1016\/j.pharep.2019.04.020","type":"journal-article","created":{"date-parts":[[2019,5,8]],"date-time":"2019-05-08T20:20:14Z","timestamp":1557346814000},"page":"839-847","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"title":["Olanzapine exposure diminishes perfusion and decreases volume of sensorimotor cortex in rats"],"prefix":"10.1007","volume":"71","author":[{"given":"Eva","family":"Drazanova","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucie","family":"Kratka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nadezda","family":"Vaskovicova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Radim","family":"Skoupy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katerina","family":"Horska","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zuzana","family":"Babinska","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hana","family":"Kotolova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucie","family":"Vrlikova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcela","family":"Buchtova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr.","given":"Zenon","family":"Starcuk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jana","family":"Ruda-Kucerova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"10.1016\/j.pharep.2019.04.020_bib0005","doi-asserted-by":"crossref","first-page":"1104","DOI":"10.1001\/jamapsychiatry.2017.2663","article-title":"Heterogeneity and homogeneity of regional brain structure in schizophrenia: a meta-analysis","volume":"74","author":"Brugger","year":"2017","journal-title":"JAMA Psychiatry"},{"key":"10.1016\/j.pharep.2019.04.020_bib0010","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1148\/radiol.10091224","article-title":"Resting-state perfusion in nonmedicated schizophrenic patients: a continuous arterial spin-labeling 3.0-T MR study","volume":"256","author":"Scheef","year":"2010","journal-title":"Radiology"},{"key":"10.1016\/j.pharep.2019.04.020_bib0015","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1001\/archgenpsychiatry.2011.88","article-title":"Changes in cortical thickness during the course of illness in schizophrenia","volume":"68","author":"van Haren","year":"2011","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.pharep.2019.04.020_bib0020","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1001\/archgenpsychiatry.2010.199","article-title":"Long-term antipsychotic treatment and brain volumes: a longitudinal study of first-episode schizophrenia","volume":"68","author":"Andreasen","year":"2011","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.pharep.2019.04.020_bib0025","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1093\/cercor\/bhn152","article-title":"Time-lapse mapping of cortical changes in schizophrenia with different treatments","volume":"19","author":"Thompson","year":"2009","journal-title":"Cereb Cortex"},{"key":"10.1016\/j.pharep.2019.04.020_bib0030","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/j.biopsych.2015.02.008","article-title":"The effect of antipsychotic treatment on cortical gray matter changes in schizophrenia: does the class matter? A meta-analysis and meta-regression of longitudinal magnetic resonance imaging studies","volume":"78","author":"Vita","year":"2015","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.pharep.2019.04.020_bib0035","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1001\/archgenpsychiatry.2010.199","article-title":"Long-term antipsychotic treatment and brain volumes: a longitudinal study of first-episode schizophrenia","volume":"68","author":"Ho","year":"2011","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.pharep.2019.04.020_bib0040","doi-asserted-by":"crossref","first-page":"1649","DOI":"10.1038\/sj.npp.1300710","article-title":"The influence of chronic exposure to antipsychotic medications on brain size before and after tissue fixation: a comparison of haloperidol and olanzapine in macaque monkeys","volume":"30","author":"Dorph-Petersen","year":"2005","journal-title":"Neuropsychopharmacol N Y"},{"key":"10.1016\/j.pharep.2019.04.020_bib0045","doi-asserted-by":"crossref","first-page":"982","DOI":"10.1016\/j.biopsych.2013.09.012","article-title":"Reduced cortical volume and elevated astrocyte density in rats chronically treated with antipsychotic drugs-linking magnetic resonance imaging findings to cellular pathology","volume":"75","author":"Vernon","year":"2014","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.pharep.2019.04.020_bib0050","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1016\/j.biopsych.2010.11.010","article-title":"Effect of chronic antipsychotic treatment on brain structure: a serial magnetic resonance imaging study with ex vivo and postmortem confirmation","volume":"69","author":"Vernon","year":"2011","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.pharep.2019.04.020_bib0055","doi-asserted-by":"crossref","first-page":"1162","DOI":"10.1111\/j.1476-5381.2011.01386.x","article-title":"Animal models of schizophrenia","volume":"164","author":"Jones","year":"2011","journal-title":"Br J Pharmacol"},{"key":"10.1016\/j.pharep.2019.04.020_bib0060","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1007\/7854_2010_62","article-title":"Animal models of schizophrenia","author":"Young","year":"2010","journal-title":"Behav Neurobiol Schizophr"},{"key":"10.1016\/j.pharep.2019.04.020_bib0065","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1016\/j.neuropharm.2007.10.010","article-title":"Effects of aripiprazole\/OPC-14597 on motor activity, pharmacological models of psychosis, and brain activity in rats","volume":"54","author":"Nordquist","year":"2008","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.pharep.2019.04.020_bib0070","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/j.brainresbull.2017.11.008","article-title":"Poly(I:C) model of schizophrenia in rats induces sex-dependent functional brain changes detected by MRI that are not reversed by aripiprazole treatment","volume":"137","author":"Drazanova","year":"2018","journal-title":"Brain Res Bull"},{"key":"10.1016\/j.pharep.2019.04.020_bib0075","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1007\/s00213-005-2204-8","article-title":"Functional magnetic resonance imaging reveals similar brain activity changes in two different animal models of schizophrenia","volume":"180","author":"Risterucci","year":"2005","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.pharep.2019.04.020_bib0080","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1002\/hbm.21436","article-title":"Acute effects of single\u2010dose aripiprazole and haloperidol on resting cerebral blood flow (rCBF) in the human brain","volume":"34","author":"Handley","year":"2013","journal-title":"Hum Brain Mapp"},{"key":"10.1016\/j.pharep.2019.04.020_bib0085","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/j.eurpsy.2009.12.005","article-title":"Characteristic brain hypoperfusion by 99mTc-ECD single photon emission computed tomography (SPECT) in patients with the first-episode schizophrenia","volume":"25","author":"Wake","year":"2010","journal-title":"Eur Psychiatry J Assoc Eur Psychiatr"},{"key":"10.1016\/j.pharep.2019.04.020_bib0090","doi-asserted-by":"crossref","first-page":"2675","DOI":"10.1038\/npp.2009.94","article-title":"Modulation of limbic circuitry predicts treatment response to antipsychotic medication: a functional imaging study in schizophrenia","volume":"34","author":"Lahti","year":"2009","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.pharep.2019.04.020_bib0095","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.pscychresns.2011.06.013","article-title":"Resting quantitative cerebral blood flow in schizophrenia measured by pulsed arterial spin labeling perfusion MRI","volume":"194","author":"Pinkham","year":"2011","journal-title":"Psychiatry Res"},{"key":"10.1016\/j.pharep.2019.04.020_bib0100","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.psyneuen.2016.07.218","article-title":"Olanzapine-depot administration induces time-dependent changes in adipose tissue endocrine function in rats","volume":"73","author":"Horska","year":"2016","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.pharep.2019.04.020_bib0105","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1038\/oby.2006.6","article-title":"Hormonal and metabolic effects of olanzapine and clozapine related to body weight in rodents","volume":"14","author":"Albaugh","year":"2006","journal-title":"Obesity"},{"key":"10.1016\/j.pharep.2019.04.020_bib0110","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1016\/j.tips.2010.07.002","article-title":"Preclinical models of antipsychotic drug-induced metabolic side effects","volume":"31","author":"Boyda","year":"2010","journal-title":"Trends Pharmacol Sci"},{"key":"10.1016\/j.pharep.2019.04.020_bib0115","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1007\/s00213-011-2555-2","article-title":"Gender-dependent consequences of chronic olanzapine in the rat: effects on body weight, inflammatory, metabolic and microbiota parameters","volume":"221","author":"Davey","year":"2012","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.pharep.2019.04.020_bib0120","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1017\/S146114571300093X","article-title":"Modelling olanzapine-induced weight gain in rats","volume":"17","author":"van der Zwaal","year":"2014","journal-title":"Int J Neuropsychopharmacol"},{"key":"10.1016\/j.pharep.2019.04.020_bib0125","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1017\/S1461145713000862","article-title":"Olanzapine depot formulation in rat: a step forward in modelling antipsychotic-induced metabolic adverse effects","volume":"17","author":"Skrede","year":"2014","journal-title":"Int J Neuropsychopharmacol"},{"key":"10.1016\/j.pharep.2019.04.020_bib0130","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1002\/1099-081X(199911)20:8<369::AID-BDD200>3.0.CO;2-6","article-title":"Pharmacokinetics and tissue distribution of olanzapine in rats","volume":"20","author":"Aravagiri","year":"1999","journal-title":"Biopharm Drug Dispos"},{"key":"10.1016\/j.pharep.2019.04.020_bib0135","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1124\/jpet.102.046987","article-title":"Antipsychotic dosing in preclinical models is often unrepresentative of the clinical condition: a suggested solution based on in vivo occupancy","volume":"305","author":"Kapur","year":"2003","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1016\/j.pharep.2019.04.020_bib0140","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1177\/0269881117691466","article-title":"Depot risperidone-induced adverse metabolic alterations in female rats","volume":"31","author":"Horska","year":"2017","journal-title":"J Psychopharmacol (Oxford)"},{"key":"10.1016\/j.pharep.2019.04.020_bib0145","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.neuropharm.2017.06.003","article-title":"Aripiprazole-induced adverse metabolic alterations in polyI:C neurodevelopmental model of schizophrenia in rats","volume":"123","author":"Horska","year":"2017","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.pharep.2019.04.020_bib0150","series-title":"The rat brain in stereotaxic coordinates","author":"Paxinos","year":"2007"},{"key":"10.1016\/j.pharep.2019.04.020_bib0155","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1093\/ilar.49.1.17","article-title":"Anesthesia and other considerations for in vivo imaging of small animals","volume":"49","author":"Hildebrandt","year":"2008","journal-title":"ILAR J"},{"key":"10.1016\/j.pharep.2019.04.020_bib0160","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1002\/hipo.1068","article-title":"Neuroimaging studies of the hippocampus in schizophrenia","volume":"11","author":"Heckers","year":"2001","journal-title":"Hippocampus"},{"issue":"17","key":"10.1016\/j.pharep.2019.04.020_bib0165","first-page":"942","article-title":"Relationship between neural, vascular, and BOLD signals in isoflurane-anesthetized rat somatosensory cortex","volume":"2007","author":"Masamoto","year":"1991","journal-title":"Cereb Cortex"},{"key":"10.1016\/j.pharep.2019.04.020_bib0170","doi-asserted-by":"crossref","first-page":"1451","DOI":"10.1002\/mrm.21779","article-title":"Validation of cerebral blood perfusion imaging as a modality for quantitative pharmacological MRI in rats","volume":"61","author":"Bruns","year":"2009","journal-title":"Magn Reson Med"},{"key":"10.1016\/j.pharep.2019.04.020_bib0175","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1002\/mrm.1178","article-title":"Cerebral perfusion during anesthesia with fentanyl, isoflurane, or pentobarbital in normal rats studied by arterial spin-labeled MRI","volume":"46","author":"Hendrich","year":"2001","journal-title":"Magn Reson Med"},{"key":"10.1016\/j.pharep.2019.04.020_bib0180","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1097\/00002142-200402000-00003","article-title":"Perfusion imaging using arterial spin labeling","volume":"15","author":"Golay","year":"2004","journal-title":"Top Magn Reson Imaging TMRI"},{"key":"10.1016\/j.pharep.2019.04.020_bib0185","doi-asserted-by":"crossref","first-page":"1240","DOI":"10.1002\/jmri.1880080610","article-title":"In vivo quantitative mapping of cardiac perfusion in rats using a noninvasive MR spin-labeling method","volume":"8","author":"Belle","year":"1998","journal-title":"J Magn Reson Imaging JMRI"},{"key":"10.1016\/j.pharep.2019.04.020_bib0190","doi-asserted-by":"crossref","first-page":"1821","DOI":"10.1038\/jcbfm.2010.160","article-title":"Determination of the brain-blood partition coefficient for water in mice using MRI","volume":"30","author":"Leithner","year":"2010","journal-title":"J Cereb Blood Flow Metab"},{"key":"10.1016\/j.pharep.2019.04.020_bib0195","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1002\/mrm.25875","article-title":"Quantitative theory for the longitudinal relaxation time of blood water","volume":"76","author":"Li","year":"2016","journal-title":"Magn Reson Med"},{"key":"10.1016\/j.pharep.2019.04.020_bib0200","first-page":"624","article-title":"The laboratory rat: relating its age with human\u2019s","volume":"4","author":"Sengupta","year":"2013","journal-title":"Int J Prev Med"},{"key":"10.1016\/j.pharep.2019.04.020_bib0205","doi-asserted-by":"crossref","first-page":"208","DOI":"10.5507\/bp.2014.060","article-title":"The common pathophysiology underlying the metabolic syndrome, schizophrenia and depression. A review","volume":"159","author":"Kucerova","year":"2015","journal-title":"Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub"},{"key":"10.1016\/j.pharep.2019.04.020_bib0210","doi-asserted-by":"crossref","first-page":"177","DOI":"10.2165\/00003088-199937030-00001","article-title":"Olanzapine. Pharmacokinetic and pharmacodynamic profile","volume":"37","author":"Callaghan","year":"1999","journal-title":"Clin Pharmacokinet"},{"key":"10.1016\/j.pharep.2019.04.020_bib0215","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/S0893-133X(99)00162-1","article-title":"In vivo olanzapine occupancy of muscarinic acetylcholine receptors in patients with schizophrenia","volume":"23","author":"Raedler","year":"2000","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.pharep.2019.04.020_bib0220","series-title":"Cereb. Blood flow Metab.","first-page":"231","article-title":"Neurovascular control of the cerebral circulation","author":"Goadsby","year":"1993"},{"key":"10.1016\/j.pharep.2019.04.020_bib0225","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1038\/1099","article-title":"Dopaminergic regulation of cerebral cortical microcirculation","volume":"1","author":"Krimer","year":"1998","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.pharep.2019.04.020_bib0230","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1016\/j.neuroimage.2005.10.029","article-title":"Brain hemodynamic changes mediated by dopamine receptors: role of the cerebral microvasculature in dopamine-mediated neurovascular coupling","volume":"30","author":"Choi","year":"2006","journal-title":"NeuroImage"},{"key":"10.1016\/j.pharep.2019.04.020_bib0235","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1038\/1074","article-title":"Neurogenic control of the cerebral microcirculation: is dopamine minding the store?","volume":"1","author":"Iadecola","year":"1998","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.pharep.2019.04.020_bib0240","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1002\/mrm.1910380306","article-title":"Detection of dopaminergic neurotransmitter activity using pharmacologic MRI: correlation with PET, microdialysis, and behavioral data","volume":"38","author":"Chen","year":"1997","journal-title":"Magn Reson Med"},{"key":"10.1016\/j.pharep.2019.04.020_bib0245","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/0893-133X(94)00129-N","article-title":"Radioreceptor binding profile of the atypical antipsychotic olanzapine","volume":"14","author":"Bymaster","year":"1996","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.pharep.2019.04.020_bib0250","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1007\/BF02245606","article-title":"Risperidone compared with new and reference antipsychotic drugs: in vitro and in vivo receptor binding","volume":"124","author":"Schotte","year":"1996","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.pharep.2019.04.020_bib0255","doi-asserted-by":"crossref","first-page":"271","DOI":"10.2165\/00023210-199810040-00005","article-title":"Serotonin 5-HT1B\/1D receptor agonists in Migraine","volume":"10","author":"Goadsby","year":"1998","journal-title":"CNS Drugs"},{"key":"10.1016\/j.pharep.2019.04.020_bib0260","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1007\/s10194-011-0415-4","article-title":"Effect of CGRP and sumatriptan on the BOLD response in visual cortex","volume":"13","author":"Asghar","year":"2012","journal-title":"J Headache Pain"},{"key":"10.1016\/j.pharep.2019.04.020_bib0265","doi-asserted-by":"crossref","first-page":"3726","DOI":"10.1073\/pnas.72.9.3726","article-title":"Central noradrenergic regulation of cerebral blood flow and vascular permeability","volume":"72","author":"Raichle","year":"1975","journal-title":"Proc Natl Acad Sci"},{"key":"10.1016\/j.pharep.2019.04.020_bib0270","series-title":"Cerebral blood flow and metabolism","author":"Edvinsson","year":"2002"},{"key":"10.1016\/j.pharep.2019.04.020_bib0275","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/0006-8993(81)90225-0","article-title":"Subtypes of \u03b2-adrenergic receptors in rat cerebral microvessels","volume":"220","author":"Kobayashi","year":"1981","journal-title":"Brain Res"},{"key":"10.1016\/j.pharep.2019.04.020_bib0280","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1016\/0014-4886(78)90108-5","article-title":"Spatial features of the rat hippocampal vascular system","volume":"58","author":"Coyle","year":"1978","journal-title":"Exp Neurol"},{"key":"10.1016\/j.pharep.2019.04.020_bib0285","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/0006-8993(82)90630-8","article-title":"Evidence for dopamine as a transmitter in dorsal hippocampus","volume":"232","author":"Ishikawa","year":"1982","journal-title":"Brain Res"},{"key":"10.1016\/j.pharep.2019.04.020_bib0290","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.schres.2007.09.015","article-title":"Regional thinning of the cerebral cortex in schizophrenia: effects of diagnosis, age and antipsychotic medication","volume":"98","author":"Nesv\u00e5g","year":"2008","journal-title":"Schizophr Res"},{"key":"10.1016\/j.pharep.2019.04.020_bib0295","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1016\/j.schres.2009.11.001","article-title":"Reduced cortical thickness in first episode schizophrenia","volume":"116","author":"Schultz","year":"2010","journal-title":"Schizophr Res"},{"key":"10.1016\/j.pharep.2019.04.020_bib0300","doi-asserted-by":"crossref","first-page":"6062","DOI":"10.1038\/s41598-019-42532-z","article-title":"Different effects of prenatal MAM vs. perinatal THC exposure on regional cerebral blood perfusion detected by Arterial Spin Labelling MRI in rats","volume":"9","author":"Drazanova","year":"2019","journal-title":"Sci Rep"}],"container-title":["Pharmacological Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1734114019300714?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1734114019300714?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,7,15]],"date-time":"2025-07-15T20:38:02Z","timestamp":1752611882000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1016\/j.pharep.2019.04.020"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10]]},"references-count":60,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2019,10]]}},"alternative-id":["S1734114019300714"],"URL":"https:\/\/doi.org\/10.1016\/j.pharep.2019.04.020","relation":{},"ISSN":["1734-1140"],"issn-type":[{"value":"1734-1140","type":"print"}],"subject":[],"published":{"date-parts":[[2019,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Olanzapine exposure diminishes perfusion and decreases volume of sensorimotor cortex in rats","name":"articletitle","label":"Article Title"},{"value":"Pharmacological Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.pharep.2019.04.020","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Institute of Pharmacology, Polish Academy of Sciences. Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}