{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T04:31:42Z","timestamp":1782361902796,"version":"3.54.5"},"reference-count":33,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Annales Pharmaceutiques Fran\u00e7aises"],"published-print":{"date-parts":[[2019,1]]},"DOI":"10.1016\/j.pharma.2018.08.002","type":"journal-article","created":{"date-parts":[[2018,9,20]],"date-time":"2018-09-20T00:01:38Z","timestamp":1537401698000},"page":"15-27","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"title":["Validated RP-HPLC method for quantification of felodipine in rabbit plasma: Application in a bioequivalence study"],"prefix":"10.1016","volume":"77","author":[{"given":"N.H.","family":"Salunkhe","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.R.","family":"Jadhav","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.D.","family":"Bhinge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.pharma.2018.08.002_bib0170","series-title":"United States Pharmacopeial Convention: The United States Pharmacopoeia 30th and The National Formulary 25th","year":"2007"},{"key":"10.1016\/j.pharma.2018.08.002_bib0175","series-title":"The complete drug reference","author":"Martindale:","year":"2009"},{"key":"10.1016\/j.pharma.2018.08.002_bib0180","series-title":"Pharmacopoeia","author":"British","year":"2013"},{"key":"10.1016\/j.pharma.2018.08.002_bib0185","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1016\/j.talanta.2005.04.028","article-title":"Development of a liquid-liquid extraction procedure for five 1,4-dihydropyridines calcium channel antagonists from human plasma using experimental design","volume":"67","author":"Baranda","year":"2005","journal-title":"Talanta"},{"key":"10.1016\/j.pharma.2018.08.002_bib0190","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1097\/00007691-200502000-00010","article-title":"Weinmann W. Quantitative determination of the calcium channel antagonists amlodipine, lercanidipine, nitrendipine, felodipine, and lacidipine in human plasma using liquid chromatography-tandem mass spectrometry","volume":"27","author":"Baranda","year":"2005","journal-title":"Ther Drug Monit"},{"key":"10.1016\/j.pharma.2018.08.002_bib0195","doi-asserted-by":"crossref","first-page":"3401","DOI":"10.1039\/c3ay41570h","article-title":"Micellar liquid chromatographic determination of felodipine in tablets and human plasma with fluorescence detection: application to stability studies and content uniformity testing","volume":"6","author":"Walash","year":"2014","journal-title":"Anal Methods"},{"issue":"4","key":"10.1016\/j.pharma.2018.08.002_bib0200","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1365\/s10337-003-0042-6","article-title":"Sensitive Determination of Felodipine in Human and Dog Plasma by Use of Liquid\u2013Liquid Extraction and LC\u2013ESI\u2013MS\u2013MS","volume":"3","author":"Kim","year":"2003","journal-title":"Chromatogr"},{"key":"10.1016\/j.pharma.2018.08.002_bib0205","doi-asserted-by":"crossref","first-page":"1330","DOI":"10.1080\/00032710903518740","article-title":"On-line SPE on restricted access adsorbent for HPLC-MS\/MS analysis of felodipine in plasma samples","volume":"43","author":"Albu","year":"2010","journal-title":"Anal Lett"},{"key":"10.1016\/j.pharma.2018.08.002_bib0210","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1007\/s40005-012-0028-1","article-title":"Development and validation of a high-throughput method for the quantitative analysis of felodipine in human plasma using high-performance liquid chromatography with mass\/mass spectrometer and its application to a bioequivalence study in healthy male Korea","volume":"42","author":"Kim","year":"2012","journal-title":"J Pharm Investig"},{"key":"10.1016\/j.pharma.2018.08.002_bib0215","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1002\/bmc.2861","article-title":"Validated LC-ESI-MS\/MS method for simultaneous quantitation of felodipine and metoprolol in rat plasma: application to a pharmacokinetic study in rats","volume":"27","author":"Kallem","year":"2013","journal-title":"Biomed Chromatogr"},{"key":"10.1016\/j.pharma.2018.08.002_bib0220","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/j.jchromb.2004.10.032","article-title":"Felodipine quantification in human plasma by high-performance liquid chromatography coupled to tandem mass spectrometry","volume":"814","author":"Miglioran\u00e7a","year":"2005","journal-title":"J Chromatogr B Anal Technol Biomed Life Sci"},{"key":"10.1016\/j.pharma.2018.08.002_bib0225","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/0378-4347(94)00579-T","article-title":"Determination of felodipine, its enantiomers, and a pyridine metabolite in human plasma by capillary gas chromatography with mass spectrometric detection","volume":"666","author":"Dru","year":"1995","journal-title":"J Chromatogr B"},{"key":"10.1016\/j.pharma.2018.08.002_bib0230","first-page":"461","article-title":"Determination of felodipine concentration in human plasma by GC-ECD and study of its pharmacokinetics","volume":"33","author":"Yang","year":"1998","journal-title":"Yao Xue Xue Bao"},{"key":"10.1016\/j.pharma.2018.08.002_bib0235","doi-asserted-by":"crossref","first-page":"2499","DOI":"10.1007\/s00216-009-3036-x","article-title":"Determination of basic drugs of abuse in human serum by online extraction and LC-MS\/MS","volume":"395","author":"Ferreir\u00f3s Bouzas","year":"2009","journal-title":"Anal Bioanal Chem"},{"key":"10.1016\/j.pharma.2018.08.002_bib0240","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/j.jchromb.2017.01.034","article-title":"Ultrasound assisted dispersive liquid-liquid microextraction coupled with high performance liquid chromatography designated for bioavailability studies of felodipine combinations in rat plasma","volume":"1046","author":"Ahmed","year":"2017","journal-title":"J Chromatogr B Anal Technol Biomed Life Sci"},{"key":"10.1016\/j.pharma.2018.08.002_bib0245","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1021\/ac053476f","article-title":"Rapid LC\/MS\/MS Method Development for Drug Discovery A three-checkpoint paradigm","author":"Xu","year":"2005","journal-title":"Anal Chem"},{"key":"10.1016\/j.pharma.2018.08.002_bib0250","series-title":"Guidance for industry: bioavailability and bioequivalence studies for orally administered drug products-general, considerations., U.S., Department of Health and Human Services Food and Drug Administration Center for Drug Evaluation and Research","year":"2003"},{"key":"10.1016\/j.pharma.2018.08.002_bib0255","series-title":"Guidance for Industry-Bioanalytical Method, Validation., U.S.","year":"2001"},{"key":"10.1016\/j.pharma.2018.08.002_bib0260","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1365\/s10337-004-0442-2","article-title":"HPLC Determination and Pharmacokinetic Study of Valdecoxib in Human Plasma","volume":"61","author":"Sane","year":"2005","journal-title":"Chromatographia"},{"issue":"3","key":"10.1016\/j.pharma.2018.08.002_bib0265","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1080\/15376516.2017.1388458","article-title":"Optimization and validation of RP-HPLC method for simultaneous estimation of palbociclib and letrozole","volume":"28","author":"Dange","year":"2018","journal-title":"Toxicol Mech Methods"},{"issue":"3","key":"10.1016\/j.pharma.2018.08.002_bib0270","first-page":"582","article-title":"Bioanalytical method development and validation for simultaneous estimation of cefixime and dicloxacillin by RP-HPLC in human plasma","volume":"61","author":"Bhinge","year":"2014","journal-title":"Acta Chim Slov"},{"key":"10.1016\/j.pharma.2018.08.002_bib0275","series-title":"Guideline on bioanalytical method validation. Committee for Medicinal Products for Human Use","author":"EMA","year":"2011"},{"key":"10.1016\/j.pharma.2018.08.002_bib0280","series-title":"Guidance for industry on bioanalytical method validation","year":"2001"},{"key":"10.1016\/j.pharma.2018.08.002_bib0285","series-title":"Q2A ICH guideline. Validation of analytical procedures text methodology","year":"2003"},{"key":"10.1016\/j.pharma.2018.08.002_bib0290","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.jpba.2005.02.045","article-title":"Simultaneous determination of lamotrigine, phenobarbitone, carbamazepine and phenytoin in human serum by high-performance liquid chromatography","volume":"39","author":"Patil","year":"2005","journal-title":"J Pharm Biomed Anal"},{"key":"10.1016\/j.pharma.2018.08.002_bib0295","doi-asserted-by":"crossref","first-page":"981","DOI":"10.14233\/ajchem.2013.13310","article-title":"Simultaneous estimation of atorvastatin calcium and fenofibrate in rabbit plasma by RP-HPLC","volume":"25","author":"Bhinge","year":"2013","journal-title":"Asian J Chem"},{"key":"10.1016\/j.pharma.2018.08.002_bib0300","first-page":"63","article-title":"V. Simultaneous estimation of cefixime and cloxacillin in human plasma by reversed phase-HPLC with UV detection","volume":"36","author":"Bhinge","year":"2012","journal-title":"Thai J Pharm Sci"},{"key":"10.1016\/j.pharma.2018.08.002_bib0305","series-title":"The Blood Morphology of Laboratory Animals.","author":"Shermer","year":"1967"},{"key":"10.1016\/j.pharma.2018.08.002_bib0310","doi-asserted-by":"crossref","first-page":"2342","DOI":"10.1016\/j.chroma.2009.11.088","article-title":"Evolution of dispersive liquid-liquid microextraction method","volume":"1217","author":"Rezaee","year":"2010","journal-title":"J Chromatogr A"},{"key":"10.1016\/j.pharma.2018.08.002_bib0315","series-title":"The United States Pharmacopoeia 35 National formulary 30","year":"2012"},{"key":"10.1016\/j.pharma.2018.08.002_bib0320","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1007\/BF00606633","article-title":"Pharmacokinetic interactions between felodipine and metoprolol","volume":"31","author":"Smith","year":"1987","journal-title":"Eur J Clin Pharmacol"},{"key":"10.1016\/j.pharma.2018.08.002_bib0325","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1007\/s002280050321","article-title":"Bioequivalence, pharmacokinetic and pharmacodynamic response to combined extended release formulations of felodipine and metoprolol in healthy volunteers","volume":"52","author":"\u00c5berg","year":"1997","journal-title":"Eur J Clin Pharmacol"},{"key":"10.1016\/j.pharma.2018.08.002_bib0330","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1111\/j.1365-2125.1991.tb05503.x","article-title":"A study of the acute pharmacodynamic interaction of ramipril and felodipine in normotensive subjects","volume":"31","author":"Bainbridge","year":"1991","journal-title":"Br J Clin Pharmacol"}],"container-title":["Annales Pharmaceutiques Fran\u00e7aises"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003450918300683?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003450918300683?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T23:33:45Z","timestamp":1757720025000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0003450918300683"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1]]},"references-count":33,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,1]]}},"alternative-id":["S0003450918300683"],"URL":"https:\/\/doi.org\/10.1016\/j.pharma.2018.08.002","relation":{},"ISSN":["0003-4509"],"issn-type":[{"value":"0003-4509","type":"print"}],"subject":[],"published":{"date-parts":[[2019,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Validated RP-HPLC method for quantification of felodipine in rabbit plasma: Application in a bioequivalence study","name":"articletitle","label":"Article Title"},{"value":"Annales Pharmaceutiques Fran\u00e7aises","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.pharma.2018.08.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Acad\u00e9mie Nationale de Pharmacie. Published by Elsevier Masson SAS. All rights reserved.","name":"copyright","label":"Copyright"}]}}