{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T23:07:21Z","timestamp":1785539241667,"version":"3.56.0"},"reference-count":16,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2019,7,1]],"date-time":"2019-07-01T00:00:00Z","timestamp":1561939200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,7,1]],"date-time":"2019-07-01T00:00:00Z","timestamp":1561939200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Annales Pharmaceutiques Fran\u00e7aises"],"published-print":{"date-parts":[[2019,7]]},"DOI":"10.1016\/j.pharma.2019.02.004","type":"journal-article","created":{"date-parts":[[2019,4,23]],"date-time":"2019-04-23T16:50:15Z","timestamp":1556038215000},"page":"295-301","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":18,"title":["RP-HPLC-UV method development and validation for simultaneous determination of terbutaline sulphate, ambroxol HCl and guaifenesin in pure and dosage forms"],"prefix":"10.1016","volume":"77","author":[{"given":"N.","family":"Itagimatha","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0634-6198","authenticated-orcid":false,"given":"D.H.","family":"Manjunatha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.pharma.2019.02.004_bib0085","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1016\/j.jscs.2012.01.006","article-title":"Development and validation of a stability-indicating LC method for simultaneous determination of related compounds of guaifenesin, terbutaline sulfate and ambroxol HCl in cough syrup formulation","volume":"18","author":"Rao","year":"2014","journal-title":"J Saudi Chem Soc"},{"issue":"6397","key":"10.1016\/j.pharma.2019.02.004_bib0090","doi-asserted-by":"crossref","first-page":"940","DOI":"10.1136\/bmj.287.6397.940","article-title":"Effect of terbutaline sulphate in chronic allergic cough","volume":"287","author":"Micallef","year":"1983","journal-title":"Br Med J"},{"key":"10.1016\/j.pharma.2019.02.004_bib0095","series-title":"Clinical Reasoning in Primary Care","author":"Gutierrez","year":"2007"},{"issue":"3","key":"10.1016\/j.pharma.2019.02.004_bib0100","first-page":"148","article-title":"A review on analytical methods for determination of guaifenesin alone and in combination with other drugs in pharmaceutical formulations","volume":"3A","author":"Acharya","year":"2017","journal-title":"Saudi J Med Pharm Sci"},{"issue":"11","key":"10.1016\/j.pharma.2019.02.004_bib0105","first-page":"4117","article-title":"Stability indicating RP-HPLC method for the determination of terbutaline sulphate, guaifensin, ambroxol hydrochloride and preservatives content in liquid formulations","volume":"4","author":"Bapatu","year":"2011","journal-title":"J Pharm Res"},{"issue":"5","key":"10.1016\/j.pharma.2019.02.004_bib0110","first-page":"476","article-title":"validation of an ion pair High performance liquid chromatography for the determination of pseudoephidrine HCl, guaifensin and dexchlorpheneramine maleate in cough and cold medicines","volume":"8","author":"Yolanda","year":"2016","journal-title":"Int J Pharm Clin Res"},{"issue":"2","key":"10.1016\/j.pharma.2019.02.004_bib0115","first-page":"312","article-title":"Development and validation of RP-HPLC and HPTLC methods analysis for simultaneous estimation of ambroxol Hcl, Dextromethomorphen HBr and guaifensin in pharmaceutical cough cold preparation and statistical comparison of developed methods","volume":"6","author":"Sagathiya","year":"2014","journal-title":"Intl J Phar Pharm Sci"},{"issue":"35","key":"10.1016\/j.pharma.2019.02.004_bib0120","doi-asserted-by":"crossref","first-page":"1156","DOI":"10.1080\/10826076.2011.615289","article-title":"Development and validation of a novel RP-HPLC method for a simultaneous determination of solbutalin sulphate, Guaifensin, Ambroxol HCl in tablet formulation","volume":"9","author":"Maithani","year":"2012","journal-title":"J Liq Chrom Rel Tech"},{"issue":"2","key":"10.1016\/j.pharma.2019.02.004_bib0125","first-page":"13","article-title":"Reverse phase method for the simultaneous estimation of terbutaline sulphate, bromohexane HCl and guaifensin in cough syrup","volume":"4","author":"Senthilraj","year":"2011","journal-title":"Asian J Pharm Clin Res"},{"key":"10.1016\/j.pharma.2019.02.004_bib0130","first-page":"1","article-title":"Development and validation of reverse phase HPLC method for simultaneous estimation of ambroxol HCl, guaifenesin and levosalbutamol in syrup","volume":"2","author":"Nirav","year":"2013","journal-title":"Pharm Anal Qual Assur"},{"issue":"8","key":"10.1016\/j.pharma.2019.02.004_bib0135","first-page":"2","article-title":"Spectroscopic simultaneous analysis of ambroxol hydrochloride, guaifensin, and terbutalin sulphate in liquid dosage form syrup","author":"Kimbahune","year":"2011","journal-title":"Int J Pharm Sci Rev Res"},{"key":"10.1016\/j.pharma.2019.02.004_bib0140","first-page":"93749","article-title":"Validated chromatographic method for simultaneous determination of guaifensin enantiomers and ambroxol hydrochloride in pharmaceutical formulation","volume":"5","author":"Saleh","year":"2015","journal-title":"Royal Soc Chem"},{"key":"10.1016\/j.pharma.2019.02.004_bib0145","doi-asserted-by":"crossref","first-page":"1507","DOI":"10.1007\/s10337-016-3158-1","article-title":"A versatile HPLC method for the simultaneous determination of bromhexine, guaifenesin, ambroxol, salbutamol\/terbutaline, pseudoephedrine, triprolidine, and chlorpheniramine maleate in cough\u2013cold syrups","volume":"79","author":"Njaria","year":"2016","journal-title":"Chromatograph"},{"key":"10.1016\/j.pharma.2019.02.004_bib0150","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.jare.2010.09.005","article-title":"High performance liquid chromatographic determination of some guaiphenesin-containing cough-cold preparations","volume":"2","author":"Korany","year":"2011","journal-title":"J Adv Res"},{"issue":"8","key":"10.1016\/j.pharma.2019.02.004_bib0155","first-page":"428","article-title":"High performance liquid chromatography method for simultaneous determination of terbutaline sulphate, guaifenesin, and ambroxol hydrochloride in formulations","volume":"38","author":"Shenoy","year":"2001","journal-title":"Indian Drugs"},{"issue":"96","key":"10.1016\/j.pharma.2019.02.004_bib0160","first-page":"27463","article-title":"International Council of Harmonization, Q2B validation of analytical procedures: methodology and availability","volume":"62","year":"1997","journal-title":"Fed Regist"}],"container-title":["Annales Pharmaceutiques Fran\u00e7aises"],"original-title":[],"language":"fr","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003450918302219?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003450918302219?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T23:33:51Z","timestamp":1757720031000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0003450918302219"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,7]]},"references-count":16,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2019,7]]}},"alternative-id":["S0003450918302219"],"URL":"https:\/\/doi.org\/10.1016\/j.pharma.2019.02.004","relation":{},"ISSN":["0003-4509"],"issn-type":[{"value":"0003-4509","type":"print"}],"subject":[],"published":{"date-parts":[[2019,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"RP-HPLC-UV method development and validation for simultaneous determination of terbutaline sulphate, ambroxol HCl and guaifenesin in pure and dosage forms","name":"articletitle","label":"Article Title"},{"value":"Annales Pharmaceutiques Fran\u00e7aises","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.pharma.2019.02.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Acad\u00e9mie Nationale de Pharmacie. Published by Elsevier Masson SAS. All rights reserved.","name":"copyright","label":"Copyright"}]}}