{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T09:58:54Z","timestamp":1788947934686,"version":"build-2803163510"},"reference-count":48,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Annales Pharmaceutiques Fran\u00e7aises"],"published-print":{"date-parts":[[2023,3]]},"DOI":"10.1016\/j.pharma.2022.08.009","type":"journal-article","created":{"date-parts":[[2022,8,28]],"date-time":"2022-08-28T11:31:50Z","timestamp":1661686310000},"page":"284-299","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"title":["In vitro profiling of fenofibrate solid dispersion mediated tablet formulation to treat high blood cholesterol"],"prefix":"10.1016","volume":"81","author":[{"given":"U.","family":"Atneriya","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Kapoor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Sainy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6645-9461","authenticated-orcid":false,"given":"R.","family":"Maheshwari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.pharma.2022.08.009_bib0245","series-title":"Dosage Form Design Considerations","first-page":"1","article-title":"Preformulation in Drug Research and Pharmaceutical Product Development","author":"Acharya","year":"2018"},{"key":"10.1016\/j.pharma.2022.08.009_bib0250","first-page":"1","article-title":"Oral disintegrating tablets: An overview","volume":"1","author":"Velmurugan","year":"2010","journal-title":"Int J Chem Pharm Sci"},{"key":"10.1016\/j.pharma.2022.08.009_bib0255","first-page":"192","article-title":"Microsponge embedded tablets for sustained delivery of nifedipine","volume":"5","author":"Maheshwari","year":"2017","journal-title":"Pharm Nanotechnol"},{"key":"10.1016\/j.pharma.2022.08.009_bib0260","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1208\/pt0804108","article-title":"Development of prednisone: polyethylene glycol 6000 fast-release tablets from solid dispersions: solid-state characterization, dissolution behavior, and formulation parameters","volume":"8","author":"Leonardi","year":"2007","journal-title":"AAPS PharmSciTech"},{"key":"10.1016\/j.pharma.2022.08.009_bib0265","first-page":"422","article-title":"Fenofibrate for diabetic retinopathy","volume":"7","author":"Stewart","year":"2018","journal-title":"Asia-Pacific J Ophthalmol"},{"key":"10.1016\/j.pharma.2022.08.009_bib0270","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/j.ijpharm.2019.04.051","article-title":"Improvement of the dissolution rate and bioavailability of fenofibrate by the supercritical anti-solvent process","volume":"564","author":"Ahn","year":"2019","journal-title":"Int J Pharm"},{"key":"10.1016\/j.pharma.2022.08.009_bib0275","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1016\/j.apsb.2015.07.003","article-title":"Insoluble drug delivery strategies: review of recent advances and business prospects","volume":"5","author":"Kalepu","year":"2015","journal-title":"Acta Pharm Sinica B"},{"key":"10.1016\/j.pharma.2022.08.009_bib0280","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1016\/j.jsps.2018.02.017","article-title":"Development of ternary solid dispersions with hydrophilic polymer and surface adsorbent for improving dissolution rate of carbamazepine","volume":"26","author":"Vojinovi\u0107","year":"2018","journal-title":"Saudi Pharm J"},{"key":"10.1016\/j.pharma.2022.08.009_bib0285","first-page":"219","article-title":"Improvement of solubility and dissolution rate of indomethacin by solid dispersions in gelucire 50\/13 and PEG4000, Saudi Pharm","volume":"17","author":"El Badry","year":"2009","journal-title":"J"},{"key":"10.1016\/j.pharma.2022.08.009_bib0290","doi-asserted-by":"crossref","first-page":"3648","DOI":"10.1021\/acs.biomac.6b01148","article-title":"An injectable hydrogel prepared using a PEG\/Vitamin E copolymer facilitating aqueous-driven gelation","volume":"17","author":"Zhang","year":"2016","journal-title":"Biomacromolecules"},{"key":"10.1016\/j.pharma.2022.08.009_bib0295","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1016\/j.colsurfb.2014.07.004","article-title":"Dorzolamide-loaded PLGA\/vitamin E TPGS nanoparticles for glaucoma therapy: Pharmacoscintigraphy study and evaluation of extended ocular hypotensive effect in rabbits","volume":"122","author":"Warsi","year":"2014","journal-title":"Colloids Surfaces B: Biointerf"},{"key":"10.1016\/j.pharma.2022.08.009_bib0300","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1039\/C5CS00674K","article-title":"New approaches from nanomedicine for treating leishmaniasis","volume":"45","author":"Guti\u00e9rrez","year":"2016","journal-title":"Chem Soc Rev"},{"issue":"82","key":"10.1016\/j.pharma.2022.08.009_bib0305","first-page":"510","article-title":"PLGA nanoparticles formed by single-or double-emulsion with vitamin E-TPGS","volume":"27","author":"McCall","year":"2013","journal-title":"J Visual Exp JoVE"},{"key":"10.1016\/j.pharma.2022.08.009_bib0310","first-page":"089","article-title":"Formulation and pharmacokinetics of vitamin E TPGS melt dispersion granules: an approach to improve oral delivery of flurbiprofen","volume":"8","author":"Mohd","year":"2016","journal-title":"J Bioequiv Availab"},{"key":"10.1016\/j.pharma.2022.08.009_bib0315","first-page":"137","article-title":"Nanolipid materials for drug delivery systems: a comprehensive review","volume":"1","author":"Negi","year":"2019","journal-title":"Char Biol Nanomater Drug Deliv"},{"issue":"10","key":"10.1016\/j.pharma.2022.08.009_bib0320","first-page":"117","article-title":"Advances in analytical chemistry and instrumentation","volume":"83","author":"Higuchi","year":"1965","journal-title":"Phase Solub Stud"},{"key":"10.1016\/j.pharma.2022.08.009_bib0325","first-page":"117","article-title":"A phase solubility technique","volume":"4","author":"Higuchi","year":"1965","journal-title":"Adv Anal Chem Instrum"},{"key":"10.1016\/j.pharma.2022.08.009_bib0330","series-title":"in: Nanotechnology-Based Approaches for Targeting and Delivery of Drugs and Genes","first-page":"256","article-title":"Solid lipid nanoparticles for targeting and delivery of drugs and genes","author":"Tekade","year":"2017"},{"key":"10.1016\/j.pharma.2022.08.009_bib0335","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.ejps.2016.11.019","article-title":"The formation and physical stability of two-phase solid dispersion systems of indomethacin in supercooled molten mixtures with different matrix formers","volume":"97","author":"Semjonov","year":"2017","journal-title":"Eur J Pharm Sci"},{"key":"10.1016\/j.pharma.2022.08.009_bib0340","doi-asserted-by":"crossref","first-page":"2142","DOI":"10.1002\/jps.24446","article-title":"Application of film-casting technique to investigate drug\u2013polymer miscibility in solid dispersion and hot-melt extrudate","volume":"104","author":"Parikh","year":"2015","journal-title":"J Pharm Sci"},{"key":"10.1016\/j.pharma.2022.08.009_bib0345","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.jpba.2015.02.047","article-title":"Solid state compatibility study and characterization of a novel degradation product of tacrolimus in formulation","volume":"110","author":"Peterka","year":"2015","journal-title":"J Pharm Biomed Anal"},{"key":"10.1016\/j.pharma.2022.08.009_bib0350","doi-asserted-by":"crossref","first-page":"2527","DOI":"10.1016\/j.xphs.2015.10.008","article-title":"Polymeric amorphous solid dispersions: a review of amorphization, crystallization, stabilization, solid-state characterization, and aqueous solubilization of biopharmaceutical classification system class II drugs","volume":"105","author":"Baghel","year":"2016","journal-title":"J Pharm Sci"},{"key":"10.1016\/j.pharma.2022.08.009_bib0355","series-title":"Basic fundamentals of drug delivery","first-page":"29","article-title":"Current developments in excipient science: implication of quantitative selection of each excipient in product development","author":"Kar","year":"2019"},{"key":"10.1016\/j.pharma.2022.08.009_bib0360","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.ejps.2015.12.018","article-title":"Pharmaceutical excipients\u2014quality, regulatory and biopharmaceutical considerations","volume":"87","author":"Elder","year":"2016","journal-title":"Eur J Pharm Sci"},{"key":"10.1016\/j.pharma.2022.08.009_bib0365","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1016\/j.jsps.2015.01.025","article-title":"Enhancement of dissolution rate of class II drugs (Hydrochlorothiazide); a comparative study of the two novel approaches; solid dispersion and liqui-solid techniques","volume":"23","author":"Khan","year":"2015","journal-title":"Saudi Pharm J"},{"key":"10.1016\/j.pharma.2022.08.009_bib0370","first-page":"15","article-title":"Formulation and evaluation of glimepiride solid dispersions and their tablet formulations for enhanced bioavailability","volume":"1","author":"Vidyadhara","year":"2011","journal-title":"Pharmanest"},{"key":"10.1016\/j.pharma.2022.08.009_bib0375","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1080\/10837450500299701","article-title":"Characteristics of rofecoxib-polyethylene glycol 4000 solid dispersions and tablets based on solid dispersions","volume":"10","author":"Liu","year":"2005","journal-title":"Pharm Dev Tech"},{"key":"10.1016\/j.pharma.2022.08.009_bib0380","doi-asserted-by":"crossref","first-page":"132","DOI":"10.22270\/jddt.v9i2-s.2473","article-title":"Formulation and evaluation of immediate release tablet of zopiclone using wet granulation method","volume":"9","author":"Bhatt","year":"2019","journal-title":"J Drug Deliv Ther"},{"key":"10.1016\/j.pharma.2022.08.009_bib0385","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.ijpharm.2015.07.030","article-title":"Investigating the effect of tablet thickness and punch curvature on density distribution using finite elements method","volume":"493","author":"Diarra","year":"2015","journal-title":"Int J Pharm"},{"key":"10.1016\/j.pharma.2022.08.009_bib0390","first-page":"59","volume":"Volume-I,","author":"Kapoor","year":"2013"},{"key":"10.1016\/j.pharma.2022.08.009_bib0395","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1002\/jps.20587","article-title":"Particle size limits to meet USP content uniformity criteria for tablets and capsules","volume":"95","author":"Rohrs","year":"2006","journal-title":"J Pharm Sci"},{"key":"10.1016\/j.pharma.2022.08.009_bib0400","doi-asserted-by":"crossref","first-page":"281376","DOI":"10.1155\/2014\/281376","article-title":"Formulation development and characterization of meclizine hydrochloride sublimated fast dissolving tablets","volume":"2014","author":"Vemula","year":"2014","journal-title":"Int Scholar Res Notices"},{"key":"10.1016\/j.pharma.2022.08.009_bib0405","doi-asserted-by":"crossref","first-page":"101942","DOI":"10.1016\/j.jddst.2020.101942","article-title":"Development and evaluation of solid dispersion based rapid disintegrating tablets of poorly water-soluble anti-diabetic drug","volume":"60","author":"Sakure","year":"2020","journal-title":"J Drug Deliv Sci Techno"},{"key":"10.1016\/j.pharma.2022.08.009_bib0410","doi-asserted-by":"crossref","first-page":"141","DOI":"10.22159\/ijap.2018v10i4.26493","article-title":"Formulation development and characterisation of meclizine hydrochloride fast dissolving tablets using solid dispersion technique","author":"Bhide","year":"2018","journal-title":"Int J Appl Pharm"},{"key":"10.1016\/j.pharma.2022.08.009_bib0415","doi-asserted-by":"crossref","first-page":"044","DOI":"10.7324\/JAPS.2020.10607","article-title":"Design and characterization of intra-oral fast dissolving tablets containing diacerein-solid dispersion","volume":"10","author":"Hasan","year":"2020","journal-title":"J Appl Pharm Sci"},{"key":"10.1016\/j.pharma.2022.08.009_bib0420","doi-asserted-by":"crossref","first-page":"294","DOI":"10.22159\/ajpcr.2019.v12i2.29784","article-title":"Solubility enhancement of celecoxib by solid dispersion technique and incorporation into topical gel","volume":"12","author":"Shaikh","year":"2019","journal-title":"Asian J Pharm Clin Res"},{"key":"10.1016\/j.pharma.2022.08.009_bib0425","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/j.ejps.2017.05.065","article-title":"Tadalafil solid dispersion formulations based on PVP\/VA S-630: Improving oral bioavailability in rats","volume":"106","author":"Choi","year":"2017","journal-title":"Eur J PharmSci"},{"key":"10.1016\/j.pharma.2022.08.009_bib0430","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1080\/03639045.2020.1716376","article-title":"Soluplus\u00ae based solid dispersion as fast disintegrating tablets: a combined experimental approach for enhancing the dissolution and antiulcer efficacy of famotidine","volume":"46","author":"Basha","year":"2020","journal-title":"Drug Dev Ind Pharm"},{"key":"10.1016\/j.pharma.2022.08.009_bib0435","first-page":"1001","article-title":"Solid dispersion approach improving dissolution rate of stiripentol: a novel antiepileptic drug","volume":"14","author":"Afifi","year":"2015","journal-title":"Iran J Pharml Res IJPR"},{"key":"10.1016\/j.pharma.2022.08.009_bib0440","series-title":"Formulation and Characterization of Ibuprofen Sustained Release Tablets by Solid Dispersion Technique","author":"Manju","year":"2018"},{"key":"10.1016\/j.pharma.2022.08.009_bib0445","doi-asserted-by":"crossref","first-page":"681","DOI":"10.3109\/03639040903449720","article-title":"In vitro and in vivo evaluation of fenofibrate solid dispersion prepared by hot-melt extrusion","volume":"36","author":"He","year":"2010","journal-title":"Drug Dev Ind Pharm"},{"key":"10.1016\/j.pharma.2022.08.009_bib0450","first-page":"147","article-title":"Formulation, characterization and in-vitro evaluation of fast dissolving tablets containing gliclazide hydrotropic solid dispersions","volume":"11","author":"Madan","year":"2017","journal-title":"Recent Pat Drug Deliv Form"},{"key":"10.1016\/j.pharma.2022.08.009_bib0455","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1080\/03639045.2018.1428339","article-title":"Enhancement of solubility and bioavailability of ambrisentan by solid dispersion using Daucus carota as a drug carrier: formulation, characterization, in vitro, and in vivo study","volume":"44","author":"Deshmane","year":"2018","journal-title":"Drug Dev Ind Pharm"},{"key":"10.1016\/j.pharma.2022.08.009_bib0460","series-title":"Formulation and Evaluation of Oral Disintegrating Tablets of Fenofibrate by Wowtab Technology using Solid Dispersion Technique","author":"Venkatesh","year":"2012"},{"key":"10.1016\/j.pharma.2022.08.009_bib0465","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.ejpb.2009.05.006","article-title":"Strongly enhanced dissolution rate of fenofibrate solid dispersion tablets by incorporation of superdisintegrants","volume":"73","author":"Srinarong","year":"2009","journal-title":"Eur J Pharm Biopharm"},{"key":"10.1016\/j.pharma.2022.08.009_bib0470","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1080\/03639040701377888","article-title":"Formulation and evaluation of rapidly disintegrating fenoverine tablets: effect of superdisintegrants","volume":"33","author":"Battu","year":"2007","journal-title":"Drug Dev Ind Pharm"},{"key":"10.1016\/j.pharma.2022.08.009_bib0475","doi-asserted-by":"crossref","first-page":"135","DOI":"10.22159\/ajpcr.2017.v10i7.17686","article-title":"Development of fast-dissolving tablets of amlodipine besylate by solid dispersion technology using poloxamer 407 and poloxamer 188","volume":"10","author":"Manimaran","year":"2017","journal-title":"Asian J Pharm Clin Res"},{"key":"10.1016\/j.pharma.2022.08.009_bib0480","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1016\/j.ijbiomac.2016.09.096","article-title":"Effect of Ca+ 2 ion on the release of diltiazem hydrochloride from matrix tablets of carboxymethyl xanthan gum graft polyacrylamide","volume":"94","author":"Badwaik","year":"2017","journal-title":"Int J Biol Macromol"}],"container-title":["Annales Pharmaceutiques Fran\u00e7aises"],"original-title":[],"language":"fr","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003450922001079?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003450922001079?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T23:38:44Z","timestamp":1757720324000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0003450922001079"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3]]},"references-count":48,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2023,3]]}},"alternative-id":["S0003450922001079"],"URL":"https:\/\/doi.org\/10.1016\/j.pharma.2022.08.009","relation":{},"ISSN":["0003-4509"],"issn-type":[{"value":"0003-4509","type":"print"}],"subject":[],"published":{"date-parts":[[2023,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"In vitro profiling of fenofibrate solid dispersion mediated tablet formulation to treat high blood cholesterol","name":"articletitle","label":"Article Title"},{"value":"Annales Pharmaceutiques Fran\u00e7aises","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.pharma.2022.08.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Acad\u00e9mie Nationale de Pharmacie. Published by Elsevier Masson SAS. All rights reserved.","name":"copyright","label":"Copyright"}]}}