{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T04:28:34Z","timestamp":1789619314122,"version":"build-2803163510"},"reference-count":62,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Annales Pharmaceutiques Fran\u00e7aises"],"published-print":{"date-parts":[[2026,5]]},"DOI":"10.1016\/j.pharma.2025.12.007","type":"journal-article","created":{"date-parts":[[2025,12,12]],"date-time":"2025-12-12T17:20:19Z","timestamp":1765560019000},"page":"465-483","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["QbD-based optimisation and level A IVIVC of gliclazide sustained-release matrix tablets using Pectin and HPMC"],"prefix":"10.1016","volume":"84","author":[{"given":"Santhosh Kumar","family":"Chinnaiyan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anjana Thekke","family":"Veedu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arya","family":"Rathnakaran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Devika Karattu","family":"Veedu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Malavika Panayanthatta","family":"Rayaroth","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arun Kumar","family":"K V","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.pharma.2025.12.007_bib0315","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/j.jconrel.2024.07.037","article-title":"Impact of immediate release film coating on the disintegration process of tablets","volume":"373","author":"Ma","year":"2024","journal-title":"J Control Release"},{"key":"10.1016\/j.pharma.2025.12.007_bib0320","doi-asserted-by":"crossref","first-page":"106119","DOI":"10.1016\/j.jddst.2024.106119","article-title":"Recent advances in polymer-based nanoformulations for enhancing oral drug delivery in diabetes","volume":"100","author":"Garg","year":"2024","journal-title":"J Drug Deliv Sci Technol"},{"key":"10.1016\/j.pharma.2025.12.007_bib0325","doi-asserted-by":"crossref","first-page":"100178","DOI":"10.1016\/j.endmts.2024.100178","article-title":"Diabetes-related hypoglycemia, contributing risk factors, glucagon prescriptions in two community hospitals","volume":"15","author":"Munugoti","year":"2024","journal-title":"Endocr Metab Sci"},{"key":"10.1016\/j.pharma.2025.12.007_bib0330","doi-asserted-by":"crossref","first-page":"1563","DOI":"10.2147\/DMSO.S339331","article-title":"Increased frequency of severe hypoglycemia with the modified-release gliclazide compared to glimepiride in diabetic older adults; propensity score-adjusted analysis","volume":"15","author":"Algendy","year":"2022","journal-title":"Diabetes Metab Syndr Obes"},{"key":"10.1016\/j.pharma.2025.12.007_bib0335","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.ejpb.2019.03.015","article-title":"Designing robust immediate release tablet formulations avoiding food effects for BCS class 3 drugs","volume":"139","author":"Zaheer","year":"2019","journal-title":"Eur J Pharm Biopharm"},{"key":"10.1016\/j.pharma.2025.12.007_bib0340","doi-asserted-by":"crossref","first-page":"107350","DOI":"10.1016\/j.eplepsyres.2024.107350","article-title":"Lacosamide extended-release capsules are bioequivalent to lacosamide immediate-release tablets: pharmacokinetic observations and simulations","volume":"202","author":"Wheless","year":"2024","journal-title":"Epilepsy Res"},{"key":"10.1016\/j.pharma.2025.12.007_bib0345","doi-asserted-by":"crossref","first-page":"125524","DOI":"10.1016\/j.ijpharm.2025.125524","article-title":"Model-supported dissolution methods for modified-release products: enteric-coated versus extended-release ketoprofen tablets","volume":"675","author":"Garc\u00eda","year":"2025","journal-title":"Int J Pharm"},{"key":"10.1016\/j.pharma.2025.12.007_bib0350","doi-asserted-by":"crossref","first-page":"103192","DOI":"10.1016\/j.jddst.2022.103192","article-title":"Development and evaluation of extended release metformin pellets suspended in teneligliptin jelly for the treatment of diabetes mellitus","volume":"70","author":"Kulkarni","year":"2022","journal-title":"J Drug Deliv Sci Technol"},{"key":"10.1016\/j.pharma.2025.12.007_bib0355","doi-asserted-by":"crossref","first-page":"105438","DOI":"10.1016\/j.jddst.2024.105438","article-title":"Polymeric linagliptin nanoparticles as a sustained release treatment for type 2 diabetes","volume":"93","author":"Abbas","year":"2024","journal-title":"J Drug Deliv Sci Technol"},{"key":"10.1016\/j.pharma.2025.12.007_bib0360","doi-asserted-by":"crossref","first-page":"106603","DOI":"10.1016\/j.jddst.2025.106603","article-title":"Development and in vitro-in vivo evaluation of a novel sustained-release tablet based on constant-release surface","volume":"105","author":"Wang","year":"2025","journal-title":"J Drug Deliv Sci Technol"},{"key":"10.1016\/j.pharma.2025.12.007_bib0365","doi-asserted-by":"crossref","first-page":"120256","DOI":"10.1016\/j.powtec.2024.120256","article-title":"Further enhancement of the sustained-release properties and stability of direct compression gel matrix bilayer tablets by controlling the particle size of HPMC and drug microencapsulation","volume":"448","author":"Liu","year":"2024","journal-title":"Powder Technol"},{"key":"10.1016\/j.pharma.2025.12.007_bib0370","doi-asserted-by":"crossref","first-page":"107178","DOI":"10.1016\/j.jddst.2025.107178","article-title":"Sustained-release tablets prepared by compression coating technology achieve similar drug release to osmotic pump tablets: Process parameters and in vitro-in vivo evaluation","volume":"111","author":"Cai","year":"2025","journal-title":"J Drug Deliv Sci Technol"},{"key":"10.1016\/j.pharma.2025.12.007_bib0375","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.jddst.2016.03.004","article-title":"Pectin\/HPMC dry powder coating formulations for colon specific targeting tablets of metronidazole","volume":"33","author":"Tung","year":"2016","journal-title":"J Drug Deliv Sci Technol"},{"key":"10.1016\/j.pharma.2025.12.007_bib0380","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.jfutfo.2024.04.009","article-title":"Review on pectin: sources, properties, health benefits and its applications in food industry","volume":"6","author":"Sharma","year":"2026","journal-title":"J Futur Foods"},{"key":"10.1016\/j.pharma.2025.12.007_bib0385","doi-asserted-by":"crossref","first-page":"109851","DOI":"10.1016\/j.foodres.2020.109851","article-title":"Role of pectin in the current trends towards low-glycaemic food consumption","volume":"140","author":"Mu\u00f1oz-Almagro","year":"2021","journal-title":"Food Res Int"},{"key":"10.1016\/j.pharma.2025.12.007_bib0390","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1016\/j.ijbiomac.2016.05.015","article-title":"Anti-diabetic effect of citrus pectin in diabetic rats and potential mechanism via PI3K\/Akt signaling pathway","volume":"89","author":"Liu","year":"2016","journal-title":"Int J Biol Macromol"},{"key":"10.1016\/j.pharma.2025.12.007_bib0395","first-page":"100","volume":"9","author":"Brockman","year":"2012","journal-title":"Hydroxypropyl methylcellulose, a viscous soluble fiber, reduces insulin resistance and decreases fatty liver in Zucker Diabetic Fatty rats. Nutr Metab (Lond)"},{"key":"10.1016\/j.pharma.2025.12.007_bib0400","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.jyp.2013.11.003","article-title":"Design and in vitro\/in vivo evaluation of extended release matrix tablets of nateglinide","volume":"5","author":"Sharma","year":"2013","journal-title":"J Young Pharm"},{"key":"10.1016\/j.pharma.2025.12.007_bib0405","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/08982104.2023.2208662","article-title":"Development and characterization of novel surface engineered Depofoam: a QbD coupled failure modes and effects analysis risk assessment-based optimization studies","volume":"34","author":"Koilpillai","year":"2024","journal-title":"J Liposome Res"},{"key":"10.1016\/j.pharma.2025.12.007_bib0410","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1016\/j.jddst.2018.01.008","article-title":"Formulation and optimization of enteric coated bilayer tablets of mesalamine by RSM: In vitro\u2013In vivo investigations and roentogenographic study","volume":"44","author":"Parmar","year":"2018","journal-title":"J Drug Deliv Sci Technol"},{"key":"10.1016\/j.pharma.2025.12.007_bib0415","doi-asserted-by":"crossref","first-page":"101389","DOI":"10.1016\/j.dmpk.2025.101389","article-title":"Establishment of DoE-IVIVC model for the pharmacokinetic prediction of ruxolitinib sustained-release dosage forms","volume":"61","author":"Shin","year":"2025","journal-title":"Drug Metab Pharmacokinet"},{"key":"10.1016\/j.pharma.2025.12.007_bib0420","doi-asserted-by":"crossref","first-page":"101387","DOI":"10.1016\/j.dmpk.2025.101387","article-title":"Prediction of the in vivo pharmacokinetics of sustained-release injections for semaglutide by a novel ivivc model combined with DoE","volume":"61","author":"Kim","year":"2025","journal-title":"Drug Metab Pharmacokinet"},{"key":"10.1016\/j.pharma.2025.12.007_bib0425","doi-asserted-by":"crossref","first-page":"121415","DOI":"10.1016\/j.ijpharm.2021.121415","article-title":"IVIVC for immediate release tablets confirms in vivo predictive dissolution testing for ibuprofen","volume":"614","author":"C\u00e1mara-Martinez","year":"2022","journal-title":"Int J Pharm"},{"key":"10.1016\/j.pharma.2025.12.007_bib0430","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1016\/j.jddst.2019.05.011","article-title":"Development of a dissolution method based on lipase for preclinical level A IVIVC of oral poly(\u025b-caprolactone) microspheres","volume":"52","author":"C\u00e1rdenas","year":"2019","journal-title":"J Drug Deliv Sci Technol"},{"key":"10.1016\/j.pharma.2025.12.007_bib0435","doi-asserted-by":"crossref","first-page":"1684","DOI":"10.1002\/jps.2600731204","article-title":"Pharmacokinetics of gliclazide in healthy and diabetic subjects","volume":"73","author":"Kobayashi","year":"1984","journal-title":"J Pharm Sci"},{"key":"10.1016\/j.pharma.2025.12.007_bib0440","first-page":"175","article-title":"Mathematical prediction of pharmacokinetic parameters-an in-vitro approach for investigating pharmaceutical products for IVIVC","volume":"4","author":"Rastogi","year":"2018","journal-title":"Futur J Pharm Sci"},{"key":"10.1016\/j.pharma.2025.12.007_bib0445","first-page":"506","article-title":"Fluidised bed granulation of two APIs: QbD approach and development of a NIR in-line monitoring method","volume":"15","author":"Gavan","year":"2020","journal-title":"Asian J Pharm Sci"},{"key":"10.1016\/j.pharma.2025.12.007_bib0450","doi-asserted-by":"crossref","first-page":"106412","DOI":"10.1016\/j.ejps.2023.106412","article-title":"Implementation of Quality by Design (QbD) for development of bilayer tablets","volume":"184","author":"Sim\u00e3o","year":"2023","journal-title":"Eur J Pharm Sci"},{"key":"10.1016\/j.pharma.2025.12.007_bib0455","doi-asserted-by":"crossref","first-page":"e20240003","DOI":"10.62958\/j.cjap.2024.003","article-title":"Effect of formulation parameters on enalapril maleate mucoadhesive buccal tablet using Quality by Design (QbD) approach","volume":"40","author":"Singh","year":"2024","journal-title":"Chinese J Appl Physiol"},{"key":"10.1016\/j.pharma.2025.12.007_bib0460","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1080\/03639045.2017.1413111","article-title":"Development of sustained release gastro-retentive tablet formulation of nicardipine hydrochloride using quality by design (QbD) approach","volume":"44","author":"Chudiwal","year":"2018","journal-title":"Drug Dev Ind Pharm"},{"key":"10.1016\/j.pharma.2025.12.007_bib0465","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1016\/j.carbpol.2014.07.021","article-title":"Mucoadhesive beads of gellan gum\/pectin intended to controlled delivery of drugs","volume":"113","author":"Prezotti","year":"2014","journal-title":"Carbohydr Polym"},{"key":"10.1016\/j.pharma.2025.12.007_bib0470","doi-asserted-by":"crossref","first-page":"3406","DOI":"10.3390\/polym14163406","article-title":"Drug-polymers composite matrix tablets: effect of hydroxypropyl methylcellulose (HPMC) K-Series on porosity, compatibility, and release behavior of the tablet containing a BCS class i drug","volume":"14","author":"Hirun","year":"2022","journal-title":"Polymers (Basel)"},{"key":"10.1016\/j.pharma.2025.12.007_bib0475","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.jsps.2012.03.006","article-title":"Formulation development and optimization of sustained release matrix tablet of Itopride HCl by response surface methodology and its evaluation of release kinetics","volume":"21","author":"Bose","year":"2013","journal-title":"Saudi Pharm J"},{"key":"10.1016\/j.pharma.2025.12.007_bib0480","doi-asserted-by":"crossref","first-page":"101957","DOI":"10.1016\/j.jsps.2024.101957","article-title":"Response Surface Methodology (RSM) approach to formulate and optimize the bilayer combination tablet of Tamsulosin and Finasteride","volume":"32","author":"Akhtar","year":"2024","journal-title":"Saudi Pharm J"},{"key":"10.1016\/j.pharma.2025.12.007_bib0485","doi-asserted-by":"crossref","first-page":"1947","DOI":"10.3390\/pharmaceutics14091947","article-title":"Pharmacokinetics and anti-diabetic studies of gliclazide nanosuspension","volume":"14","author":"Sampathi","year":"2022","journal-title":"Pharmaceutics"},{"key":"10.1016\/j.pharma.2025.12.007_bib0490","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/j.carbpol.2014.01.037","article-title":"Development of controlled release tablet by optimizing HPMC: Consideration of theoretical release and RSM","volume":"104","author":"Pani","year":"2014","journal-title":"Carbohydr Polym"},{"key":"10.1016\/j.pharma.2025.12.007_bib0495","doi-asserted-by":"crossref","first-page":"120718","DOI":"10.1016\/j.ijpharm.2021.120718","article-title":"Effect of gastrointestinal transit on micro-environmental pH inside HPMC matrix tablets\u2013in vitro study","volume":"604","author":"Vrbanac","year":"2021","journal-title":"Int J Pharm"},{"key":"10.1016\/j.pharma.2025.12.007_bib0500","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.carbpol.2017.06.049","article-title":"Physicochemical and powder characteristics of various citrus pectins and their application for oral pharmaceutical tablets","volume":"174","author":"Chomto","year":"2017","journal-title":"Carbohydr Polym"},{"key":"10.1016\/j.pharma.2025.12.007_bib0505","doi-asserted-by":"crossref","first-page":"101246","DOI":"10.1016\/j.jddst.2019.101246","article-title":"The influence of different mechanical stress on the release properties of HPMC matrix tablets in sucrose-NaCl media","volume":"54","author":"Vrbanac","year":"2019","journal-title":"J Drug Deliv Sci Technol"},{"key":"10.1016\/j.pharma.2025.12.007_bib0510","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1016\/j.crfs.2022.03.014","article-title":"The relative importance of internal and external physical resistances to mass transfer for caffeine release from apple pectin tablets","volume":"5","author":"Cheng","year":"2022","journal-title":"Curr Res Food Sci"},{"key":"10.1016\/j.pharma.2025.12.007_bib0515","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.ejpb.2022.12.013","article-title":"In vitro and in vivo evaluation of a pH-, microbiota- and time-based oral delivery platform for colonic release","volume":"183","author":"Moutaharrik","year":"2023","journal-title":"Eur J Pharm Biopharm"},{"key":"10.1016\/j.pharma.2025.12.007_bib0520","doi-asserted-by":"crossref","first-page":"542","DOI":"10.4274\/tjps.galenos.2019.99896","article-title":"Investigation of pectin-hydroxypropyl methylcellulose-coated floating beads for pulsatile release of piroxicam","volume":"17","author":"Kamble","year":"2020","journal-title":"Turkish J Pharm Sci"},{"key":"10.1016\/j.pharma.2025.12.007_bib0525","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1016\/j.ejpb.2007.04.016","article-title":"Biphasic release of indomethacin from HPMC\/pectin\/calcium matrix tablet: I. Characterization and mechanistic study","volume":"67","author":"Wu","year":"2007","journal-title":"Eur J Pharm Biopharm"},{"key":"10.1016\/j.pharma.2025.12.007_bib0530","doi-asserted-by":"crossref","first-page":"253","DOI":"10.2174\/2211738507666181221142406","article-title":"Development and characterization of metformin loaded pectin nanoparticles for t2 diabetes mellitus","volume":"6","author":"Chinnaiyan","year":"2019","journal-title":"Pharm Nanotechnol"},{"key":"10.1016\/j.pharma.2025.12.007_bib0535","doi-asserted-by":"crossref","first-page":"119343","DOI":"10.1016\/j.ijpharm.2020.119343","article-title":"Characterization of a novel hydroxypropyl methylcellulose (HPMC) direct compression grade excipient for pharmaceutical tablets","volume":"583","author":"Allenspach","year":"2020","journal-title":"Int J Pharm"},{"key":"10.1016\/j.pharma.2025.12.007_bib0540","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1016\/j.xphs.2024.10.016","article-title":"Mechanisms of drug release from a melt-milled, poorly soluble drug substance","volume":"114","author":"Sleziona","year":"2025","journal-title":"J Pharm Sci"},{"key":"10.1016\/j.pharma.2025.12.007_bib0545","doi-asserted-by":"crossref","first-page":"94","DOI":"10.4103\/1735-3327.330875","article-title":"Drug release kinetics and biological properties of a novel local drug carrier system","volume":"18","author":"Shafiei","year":"2021","journal-title":"Dent Res J (Isfahan)"},{"key":"10.1016\/j.pharma.2025.12.007_bib0550","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.ijpharm.2015.08.027","article-title":"Pectin\/anhydrous dibasic calcium phosphate matrix tablets for in vitro controlled release of water-soluble drug","volume":"494","author":"Mamani","year":"2015","journal-title":"Int J Pharm"},{"key":"10.1016\/j.pharma.2025.12.007_bib0555","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1080\/03639040600920630","article-title":"In vitro measurements of mucoadhesive properties of six types of pectin","volume":"33","author":"Hagesaether","year":"2007","journal-title":"Drug Dev Ind Pharm"},{"key":"10.1016\/j.pharma.2025.12.007_bib0560","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1081\/DDC-120003456","article-title":"Influence of hydroxypropyl methylcellulose mixture, apparent viscosity, and tablet hardness on drug release using a 2 3 full factorial design","volume":"28","author":"Khanvilkar","year":"2002","journal-title":"Drug Dev Ind Pharm"},{"key":"10.1016\/j.pharma.2025.12.007_bib0565","doi-asserted-by":"crossref","first-page":"102004","DOI":"10.1016\/j.jddst.2020.102004","article-title":"Effect of co-administration of probiotics with guar gum, pectin and eudragit S100 based colon targeted mini tablets containing 5-Fluorouracil for site specific release","volume":"60","author":"Kumar","year":"2020","journal-title":"J Drug Deliv Sci Technol"},{"key":"10.1016\/j.pharma.2025.12.007_bib0570","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/S0378-5173(02)00546-X","article-title":"Leaching of pectin from mixed films containing pectin, chitosan and HPMC intended for biphasic drug delivery","volume":"250","author":"Ofori-Kwakye","year":"2003","journal-title":"Int J Pharm"},{"key":"10.1016\/j.pharma.2025.12.007_bib0575","doi-asserted-by":"crossref","first-page":"140370","DOI":"10.1016\/j.foodchem.2024.140370","article-title":"Structural characteristics and gelling properties of citrus pectins after chemical and enzymatic modifications: conformation plays a vital role in Ca2+-induced gelation","volume":"459","author":"Cui","year":"2024","journal-title":"Food Chem"},{"key":"10.1016\/j.pharma.2025.12.007_bib0580","doi-asserted-by":"crossref","first-page":"46","DOI":"10.2174\/1872211308666140225143926","article-title":"Effect of HPMC\u2013E15 LV premium polymer on release profile and compression characteristics of chitosan\/pectin colon targeted mesalamine matrix tablets and in vitro study on effect of pH impact on the drug release profile","volume":"8","author":"Newton","year":"2014","journal-title":"Recent Pat Drug Deliv Formul"},{"key":"10.1016\/j.pharma.2025.12.007_bib0585","first-page":"451","article-title":"Formulation and evaluation of hydroxypropyl methylcellulose-based controlled release matrix tablets for theophylline","volume":"73","author":"Sekharan","year":"2011","journal-title":"Indian J Pharm Sci"},{"key":"10.1016\/j.pharma.2025.12.007_bib0590","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/j.jddst.2019.03.033","article-title":"Quality-by-Design based development and characterization of pioglitazone loaded liquisolid compact tablets with improved biopharmaceutical attributes","volume":"51","author":"Bonthagarala","year":"2019","journal-title":"J Drug Deliv Sci Technol"},{"key":"10.1016\/j.pharma.2025.12.007_bib0595","doi-asserted-by":"crossref","first-page":"149","DOI":"10.3329\/dujps.v13i2.21893","article-title":"Preparation and characterization of Gliclazide incorporated Cellulosic Microspheres: studies on drug release, compatibility and micromeritics","volume":"13","author":"Ayon","year":"2015","journal-title":"Dhaka Univ J Pharm Sci"},{"key":"10.1016\/j.pharma.2025.12.007_bib0600","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1016\/j.ijbiomac.2018.12.009","article-title":"Combined synergetic potential of metformin loaded pectin-chitosan biohybrids nanoparticle for NIDDM","volume":"125","author":"Chinnaiyan","year":"2019","journal-title":"Int J Biol Macromol"},{"key":"10.1016\/j.pharma.2025.12.007_bib0605","doi-asserted-by":"crossref","first-page":"107020","DOI":"10.1016\/j.ultsonch.2024.107020","article-title":"Degradation of hydroxypropyl methylcellulose (HPMC) by acoustic and hydrodynamic cavitation","volume":"109","author":"Zupanc","year":"2024","journal-title":"Ultrason Sonochem"},{"key":"10.1016\/j.pharma.2025.12.007_bib0610","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1016\/j.ejpb.2008.08.002","article-title":"Use of spray-dried chitosan acetate and ethylcellulose as compression coats for colonic drug delivery: effect of swelling on triggering in vitro drug release","volume":"71","author":"Nunthanid","year":"2009","journal-title":"Eur J Pharm Biopharm"},{"key":"10.1016\/j.pharma.2025.12.007_bib0615","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/S0939-6411(01)00225-9","article-title":"In vitro evaluation of pectin\u2013HPMC compression coated 5-aminosalicylic acid tablets for colonic delivery","volume":"53","author":"Turkoglu","year":"2002","journal-title":"Eur J Pharm Biopharm"},{"key":"10.1016\/j.pharma.2025.12.007_bib0620","first-page":"743","article-title":"Development of in vitro-in vivo correlation for encapsulated metoprolol tartrate","volume":"70","author":"Khaled","year":"2013","journal-title":"Acta Pol Pharm"}],"container-title":["Annales Pharmaceutiques Fran\u00e7aises"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003450925002160?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003450925002160?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T16:45:26Z","timestamp":1776357926000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0003450925002160"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5]]},"references-count":62,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,5]]}},"alternative-id":["S0003450925002160"],"URL":"https:\/\/doi.org\/10.1016\/j.pharma.2025.12.007","relation":{},"ISSN":["0003-4509"],"issn-type":[{"value":"0003-4509","type":"print"}],"subject":[],"published":{"date-parts":[[2026,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"QbD-based optimisation and level A IVIVC of gliclazide sustained-release matrix tablets using Pectin and HPMC","name":"articletitle","label":"Article Title"},{"value":"Annales Pharmaceutiques Fran\u00e7aises","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.pharma.2025.12.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Acad\u00e9mie Nationale de Pharmacie. Published by Elsevier Masson SAS. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}