{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T18:19:52Z","timestamp":1789237192439,"version":"build-2803163510"},"reference-count":217,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2012,7,1]],"date-time":"2012-07-01T00:00:00Z","timestamp":1341100800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pharmacological Research"],"published-print":{"date-parts":[[2012,7]]},"DOI":"10.1016\/j.phrs.2012.03.002","type":"journal-article","created":{"date-parts":[[2012,3,17]],"date-time":"2012-03-17T00:01:47Z","timestamp":1331942507000},"page":"19-32","source":"Crossref","is-referenced-by-count":56,"title":["Protecting the retinal neurons from glaucoma: Lowering ocular pressure is not enough"],"prefix":"10.1016","volume":"66","author":[{"given":"Alessia","family":"Pascale","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Filippo","family":"Drago","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Govoni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.phrs.2012.03.002_bib0005","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1098\/rspb.1975.0133","article-title":"Interplexiform cells of the mammalian retina and their comparison with catecholamine-containing retinal cells","volume":"191","author":"Boycott","year":"1975","journal-title":"Proc R Soc Lond B Biol Sci"},{"key":"10.1016\/j.phrs.2012.03.002_bib0010","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1083\/jcb.201006020","article-title":"The cell biology of vision","volume":"190","author":"Sung","year":"2010","journal-title":"J Cell Biol"},{"key":"10.1016\/j.phrs.2012.03.002_bib0015","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1152\/physiol.00038.2009","article-title":"Phagocytosis of retinal rod and cone photoreceptors","volume":"25","author":"Kevany","year":"2010","journal-title":"Physiology (Bethesda)"},{"key":"10.1016\/j.phrs.2012.03.002_bib0020","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/j.preteyeres.2004.03.001","article-title":"Dark adaptation and the retinoid cycle of vision","volume":"23","author":"Lamb","year":"2004","journal-title":"Prog Retin Eye Res"},{"key":"10.1016\/j.phrs.2012.03.002_bib0025","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1016\/j.cell.2009.09.029","article-title":"Phototransduction motifs and variations","volume":"139","author":"Yau","year":"2009","journal-title":"Cell"},{"key":"10.1016\/j.phrs.2012.03.002_bib0030","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1017\/S0952523810000209","article-title":"Multiple pathways of inhibition shape bipolar cell responses in the retina","volume":"28","author":"Eggers","year":"2011","journal-title":"Visual Neurosci"},{"key":"10.1016\/j.phrs.2012.03.002_bib0035","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/j.preteyeres.2010.03.005","article-title":"Complexity of retinal cone bipolar cells","volume":"29","author":"Strettoi","year":"2010","journal-title":"Prog Retin Eye Res"},{"key":"10.1016\/j.phrs.2012.03.002_bib0040","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1016\/j.preteyeres.2008.03.003","article-title":"Regulation of ON bipolar cell activity","volume":"27","author":"Snellman","year":"2008","journal-title":"Prog Retin Eye Res"},{"key":"10.1016\/j.phrs.2012.03.002_bib0045","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1016\/0896-6273(93)90082-3","article-title":"The contribution of NMDA and non-NMDA receptors to the light-evoked input-output characteristics of retinal ganglion cells","volume":"11","author":"Diamond","year":"1993","journal-title":"Neuron"},{"key":"10.1016\/j.phrs.2012.03.002_bib0050","doi-asserted-by":"crossref","first-page":"1260","DOI":"10.1152\/jn.1994.72.3.1260","article-title":"Ligand-gated currents of alpha and beta ganglion cells in the cat retinal slice","volume":"72","author":"Cohen","year":"1994","journal-title":"J Neurophysiol"},{"key":"10.1016\/j.phrs.2012.03.002_bib0055","doi-asserted-by":"crossref","first-page":"2165","DOI":"10.1523\/JNEUROSCI.22-06-02165.2002","article-title":"Synaptically released glutamate activates extrasynaptic NMDA receptors on cells in the ganglion cell layer of rat retina","volume":"22","author":"Chen","year":"2002","journal-title":"J Neurosci"},{"key":"10.1016\/j.phrs.2012.03.002_bib0060","series-title":"Webvision: the organization of the retina and visual system [Internet]","article-title":"Development of cell types and synaptic connections in the retina","author":"Morgan","year":"2005"},{"key":"10.1016\/j.phrs.2012.03.002_bib0065","doi-asserted-by":"crossref","first-page":"17087","DOI":"10.1073\/pnas.1011782107","article-title":"Parallel information processing channels created in the retina","volume":"107","author":"Schiller","year":"2010","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.phrs.2012.03.002_bib0070","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1016\/0042-6989(81)90013-4","article-title":"Amacrine cells, bipolar cells and ganglion cells of the cat retina: a Golgi study","volume":"21","author":"Kolb","year":"1981","journal-title":"Vision Res"},{"key":"10.1016\/j.phrs.2012.03.002_bib0075","series-title":"Webvision: the organization of the retina and visual system [Internet]","article-title":"Roles of amacrine cells","author":"Kolb","year":"1995"},{"key":"10.1016\/j.phrs.2012.03.002_bib0080","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1016\/j.tins.2005.06.002","article-title":"The many roles of starburst amacrine cells","volume":"28","author":"Masland","year":"2005","journal-title":"Trends Neurosci"},{"key":"10.1016\/j.phrs.2012.03.002_bib0085","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1016\/j.neuron.2004.11.015","article-title":"A developmental switch in the excitability and function of the starburst network in the mammalian retina","volume":"44","author":"Zheng","year":"2004","journal-title":"Neuron"},{"key":"10.1016\/j.phrs.2012.03.002_bib0090","doi-asserted-by":"crossref","first-page":"4371","DOI":"10.1113\/jphysiol.2008.159020","article-title":"Synaptic physiology of direction selectivity in the retina","volume":"586","author":"Zhou","year":"2008","journal-title":"J Physiol"},{"key":"10.1016\/j.phrs.2012.03.002_bib0095","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1002\/cne.21784","article-title":"Anatomical and neurochemical characterization of dopaminergic interplexiform processes in mouse and rat retinas","volume":"510","author":"Witkovsky","year":"2008","journal-title":"J Comp Neurol"},{"key":"10.1016\/j.phrs.2012.03.002_bib0100","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1152\/jn.00876.2009","article-title":"Role of neurotransmitter receptors in mediating light-evoked responses in retinal interplexiform cells","volume":"103","author":"Jiang","year":"2010","journal-title":"J Neurophysiol"},{"key":"10.1016\/j.phrs.2012.03.002_bib0105","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1023\/B:DOOP.0000019487.88486.0a","article-title":"Dopamine and retinal function","volume":"108","author":"Witkovsky","year":"2004","journal-title":"Doc Ophthalmol"},{"key":"10.1016\/j.phrs.2012.03.002_bib0110","series-title":"Webvision: the organization of the retina and visual system [Internet]","article-title":"S-potentials and horizontal cells","author":"Perlman","year":"1995"},{"key":"10.1016\/j.phrs.2012.03.002_bib0115","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1111\/j.1471-4159.2010.07114.x","article-title":"Mammalian retinal horizontal cells are unconventional GABAergic neurons","volume":"116","author":"Deniz","year":"2011","journal-title":"J Neurochem"},{"key":"10.1016\/j.phrs.2012.03.002_bib0120","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1002\/cne.902920203","article-title":"M\u00fcller cells in adult rabbit retinae: morphology, distribution and implications for function and development","volume":"292","author":"Robinson","year":"1990","journal-title":"J Comp Neurol"},{"key":"10.1016\/j.phrs.2012.03.002_bib0125","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/0166-2236(96)10040-0","article-title":"The M\u00fcller cell: a functional element of the retina","volume":"19","author":"Newman","year":"1996","journal-title":"Trends Neurosci"},{"key":"10.1016\/j.phrs.2012.03.002_bib0130","doi-asserted-by":"crossref","first-page":"1466","DOI":"10.1007\/s11064-008-9604-1","article-title":"M\u00fcller glia as an active compartment modulating nervous activity in the vertebrate retina: neurotransmitters and trophic factors","volume":"33","author":"de Melo Reis","year":"2008","journal-title":"Neurochem Res"},{"key":"10.1016\/j.phrs.2012.03.002_bib0135","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/0006-8993(93)90901-X","article-title":"Glutamate as a neuron-to-glial signal for mitogenesis: role of glial N-methyl-d-aspartate receptors","volume":"613","author":"Uchihori","year":"1993","journal-title":"Brain Res"},{"key":"10.1016\/j.phrs.2012.03.002_bib0140","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1017\/S0952523800007562","article-title":"Activation of NMDA receptor-channels in human retinal M\u00fcller glial cells inhibits inward-rectifying potassium currents","volume":"13","author":"Puro","year":"1996","journal-title":"Vis Neurosci"},{"key":"10.1016\/j.phrs.2012.03.002_bib0145","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1002\/glia.440090206","article-title":"Excitatory amino acid-induced phosphoinositide hydrolysis in M\u00fcller glia","volume":"9","author":"L\u00f3pez-Colom\u00e9","year":"1993","journal-title":"Glia"},{"key":"10.1016\/j.phrs.2012.03.002_bib0150","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1097\/00001756-199401120-00034","article-title":"AMPA\/KA receptor expression in radial glia","volume":"5","author":"L\u00f3pez","year":"1994","journal-title":"Neuroreport"},{"key":"10.1016\/j.phrs.2012.03.002_bib0155","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1002\/glia.20004","article-title":"GABA(A) receptors in M\u00fcller glial cells of the human retina","volume":"46","author":"Biedermann","year":"2004","journal-title":"Glia"},{"key":"10.1016\/j.phrs.2012.03.002_bib0160","doi-asserted-by":"crossref","first-page":"1833","DOI":"10.1097\/00001756-199906230-00006","article-title":"GABA(B) receptors in M\u00fcller cells of the bullfrog retina","volume":"10","author":"Zhang","year":"1999","journal-title":"Neuroreport"},{"key":"10.1016\/j.phrs.2012.03.002_bib0165","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1038\/85090","article-title":"M\u00fcller glia are a potential source of neural regeneration in the postnatal chicken retina","volume":"4","author":"Fischer","year":"2001","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.phrs.2012.03.002_bib0170","doi-asserted-by":"crossref","first-page":"5533","DOI":"10.1523\/JNEUROSCI.4733-09.2010","article-title":"The ON pathway rectifies the OFF pathway of the mammalian retina","volume":"30","author":"Liang","year":"2010","journal-title":"J Neurosci"},{"key":"10.1016\/j.phrs.2012.03.002_bib0175","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1002\/cne.901640302","article-title":"Monkey retinal ganglion cells: morphometric analysis and tracing of axonal projections, with a consideration of the peroxidase technique","volume":"164","author":"Bunt","year":"1975","journal-title":"J Comp Neurol"},{"key":"10.1016\/j.phrs.2012.03.002_bib0180","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.1016\/0306-4522(84)90006-X","article-title":"Retinal ganglion cells that project to the dorsal lateral geniculate nucleus in the macaque monkey","volume":"12","author":"Perry","year":"1984","journal-title":"Neuroscience"},{"key":"10.1016\/j.phrs.2012.03.002_bib0185","first-page":"4","article-title":"What is the global burden of visual impairment","volume":"16","author":"Dandona","year":"2006","journal-title":"BMC Med"},{"key":"10.1016\/j.phrs.2012.03.002_bib0190","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1097\/00000446-200611000-00019","article-title":"Sensory impairment in older adults: part 2: vision loss","volume":"106","author":"Whiteside","year":"2006","journal-title":"Am J Nurs"},{"key":"10.1016\/j.phrs.2012.03.002_bib0195","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1097\/WNO.0b013e318177edf0","article-title":"Dendritic and synaptic protection: is it enough to save the retinal ganglion cell body and axon","volume":"28","author":"Morquette","year":"2008","journal-title":"J Neuroophthalmol"},{"key":"10.1016\/j.phrs.2012.03.002_bib0200","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1016\/0002-9394(84)90509-9","article-title":"The effect of age on the nerve fiber population of the human optic nerve","volume":"97","author":"Balazsi","year":"1984","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.phrs.2012.03.002_bib0205","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/S0161-6420(89)32928-9","article-title":"The effect of age on normal human optic nerve fiber number and diameter","volume":"96","author":"Repka","year":"1989","journal-title":"Ophthalmology"},{"key":"10.1016\/j.phrs.2012.03.002_bib0210","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/0014-4835(86)90022-9","article-title":"Evidence of cell loss from the rat retina during senescence","volume":"42","author":"Katz","year":"1986","journal-title":"Exp Eye Res"},{"key":"10.1016\/j.phrs.2012.03.002_bib0215","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1159\/000055471","article-title":"A morphological and morphometrical study of the retina in aging SAM mice","volume":"30","author":"Shoji","year":"1998","journal-title":"Ophthalmic Res"},{"key":"10.1016\/j.phrs.2012.03.002_bib0220","doi-asserted-by":"crossref","first-page":"12156","DOI":"10.1073\/pnas.0605211103","article-title":"Dendrites of rod bipolar cells sprout in normal aging retina","volume":"103","author":"Liets","year":"2006","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.phrs.2012.03.002_bib0225","doi-asserted-by":"crossref","first-page":"2824","DOI":"10.1167\/iovs.06-1228","article-title":"Cellular reorganization in the human retina during normal aging","volume":"48","author":"Eliasieh","year":"2007","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.phrs.2012.03.002_bib0230","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1016\/j.exer.2011.01.014","article-title":"Dendritic changes in visual pathways in glaucoma and other neurodegenerative conditions","volume":"92","author":"Liu","year":"2011","journal-title":"Exp Eye Res"},{"key":"10.1016\/j.phrs.2012.03.002_bib0235","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.1016\/S0140-6736(10)61423-7","article-title":"Glaucoma","volume":"377","author":"Quigley","year":"2011","journal-title":"Lancet"},{"key":"10.1016\/j.phrs.2012.03.002_bib0240","doi-asserted-by":"crossref","first-page":"2663","DOI":"10.1167\/iovs.04-1070","article-title":"Glaucoma: macrocosm to microcosm: the Friedenwald lecture","volume":"46","author":"Quigley","year":"2005","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.phrs.2012.03.002_bib0245","first-page":"844","article-title":"Global data on visual impairment in the year 2002","volume":"82","author":"Resnikoff","year":"2004","journal-title":"Bull World Health Organ"},{"key":"10.1016\/j.phrs.2012.03.002_bib0250","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1007\/s10384-009-0735-y","article-title":"Fixation behavior in advanced stage glaucoma assessed by the MicroPerimeter MP-1","volume":"53","author":"Kameda","year":"2009","journal-title":"Jpn J Ophthalmol"},{"key":"10.1016\/j.phrs.2012.03.002_bib0255","doi-asserted-by":"crossref","first-page":"S19","DOI":"10.1016\/j.ajo.2004.04.058","article-title":"An evidence-based assessment of risk factors for the progression of ocular hypertension and glaucoma","volume":"138","author":"Friedman","year":"2004","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.phrs.2012.03.002_bib0260","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1001\/archopht.122.4.532","article-title":"Prevalence of open-angle glaucoma among adults in the United States","volume":"122","author":"Friedman","year":"2004","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.phrs.2012.03.002_bib0265","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1016\/j.ajo.2007.07.040","article-title":"Association between intraocular pressure variation and glaucoma progression: data from a United States chart review","volume":"144","author":"Lee","year":"2007","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.phrs.2012.03.002_bib0270","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1136\/bmj.328.7431.97","article-title":"Glaucoma\u20141: diagnosis","volume":"328","author":"Khaw","year":"2004","journal-title":"BMJ"},{"key":"10.1016\/j.phrs.2012.03.002_bib0275","doi-asserted-by":"crossref","first-page":"4393","DOI":"10.1113\/jphysiol.2008.156729","article-title":"Effects of optic nerve injury, glaucoma, and neuroprotection on the survival, structure, and function of ganglion cells in the mammalian retina","volume":"586","author":"Weber","year":"2008","journal-title":"J Physiol"},{"key":"10.1016\/j.phrs.2012.03.002_bib0280","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1136\/bjo.82.6.680","article-title":"Axon deviation in the human lamina cribrosa","volume":"82","author":"Morgan","year":"1998","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.phrs.2012.03.002_bib0285","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.1076\/ceyr.16.10.1024.9024","article-title":"Effects of changes in intraocular pressure on human ocular haemodynamics","volume":"16","author":"Findl","year":"1997","journal-title":"Curr Eye Res"},{"key":"10.1016\/j.phrs.2012.03.002_bib0290","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1006\/exer.1996.0263","article-title":"Autoregulation of human optic nerve head circulation in response to increased intraocular pressure","volume":"64","author":"Pillunat","year":"1997","journal-title":"Exp Eye Res"},{"key":"10.1016\/j.phrs.2012.03.002_bib0295","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1001\/archopht.1997.01100150499009","article-title":"Nitric oxide synthase in the human glaucomatous optic nerve head","volume":"115","author":"Neufeld","year":"1997","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.phrs.2012.03.002_bib0300","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/j.exer.2010.08.005","article-title":"Pathophysiology of human glaucomatous optic nerve damage: insights from rodent models of glaucoma","volume":"93","author":"Morrison","year":"2011","journal-title":"Exp Eye Res"},{"key":"10.1016\/j.phrs.2012.03.002_bib0305","first-page":"951","article-title":"Essential iris atrophy, pigment dispersion, and glaucoma in DBA\/2J mice","volume":"39","author":"John","year":"1998","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.phrs.2012.03.002_bib0310","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1007\/s00441-004-1062-8","article-title":"Changes in retinal neuronal populations in the DBA\/2J mouse","volume":"320","author":"Moon","year":"2005","journal-title":"Cell Tissue Res"},{"key":"10.1016\/j.phrs.2012.03.002_bib0315","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1186\/1471-2202-7-66","article-title":"Progressive ganglion cell loss and optic nerve degeneration in DBA\/2J mice is variable and asymmetric","volume":"7","author":"Schlamp","year":"2006","journal-title":"BMC Neurosci"},{"key":"10.1016\/j.phrs.2012.03.002_bib0320","doi-asserted-by":"crossref","first-page":"3161","DOI":"10.1167\/iovs.06-1282","article-title":"Global changes in optic nerve head gene expression after exposure to elevated intraocular pressure in a rat glaucoma model","volume":"48","author":"Johnson","year":"2007","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.phrs.2012.03.002_bib0325","doi-asserted-by":"crossref","first-page":"3003","DOI":"10.1167\/iovs.09-4663","article-title":"Retinal cell responses to elevated intraocular pressure: a gene array comparison between the whole retina and retinal ganglion cell layer","volume":"51","author":"Guo","year":"2010","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.phrs.2012.03.002_bib0330","first-page":"2304","article-title":"Morphology of single ganglion cells in the glaucomatous primate retina","volume":"39","author":"Weber","year":"1998","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.phrs.2012.03.002_bib0335","doi-asserted-by":"crossref","first-page":"3197","DOI":"10.1167\/iovs.04-0834","article-title":"Structure-function relations of parasol cells in the normal and glaucomatous primate retina","volume":"46","author":"Weber","year":"2005","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.phrs.2012.03.002_bib0340","doi-asserted-by":"crossref","first-page":"2735","DOI":"10.1523\/JNEUROSCI.4443-07.2008","article-title":"Progressive ganglion cell degeneration precedes neuronal loss in a mouse model of glaucoma","volume":"28","author":"Buckingham","year":"2008","journal-title":"J Neurosci"},{"key":"10.1016\/j.phrs.2012.03.002_bib0345","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1097\/00061198-199610000-00010","article-title":"Retinal ganglion cell death in glaucoma: the how, the why, and the maybe","volume":"5","author":"Nickells","year":"1996","journal-title":"J Glaucoma"},{"key":"10.1016\/j.phrs.2012.03.002_bib0350","doi-asserted-by":"crossref","first-page":"S277","DOI":"10.1016\/S0039-6257(01)00207-7","article-title":"Maintaining mitochondrial membrane impermeability. An opportunity for new therapy in glaucoma?","volume":"45","author":"Tatton","year":"2001","journal-title":"Surv Ophthalmol"},{"key":"10.1016\/j.phrs.2012.03.002_bib0355","first-page":"771","article-title":"Effect of intraocular pressure on rapid axoplasmic transport in monkey optic nerve","volume":"13","author":"Anderson","year":"1974","journal-title":"Invest Ophthalmol"},{"key":"10.1016\/j.phrs.2012.03.002_bib0360","first-page":"126","article-title":"Chronic experimental glaucoma in primates. I. Production of elevated intraocular pressure by anterior chamber injection of autologous ghost red blood cells","volume":"19","author":"Quigley","year":"1980","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.phrs.2012.03.002_bib0365","first-page":"966","article-title":"BDNF enhances retinal ganglion cell survival in cats with optic nerve damage","volume":"42","author":"Chen","year":"2001","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.phrs.2012.03.002_bib0370","doi-asserted-by":"crossref","first-page":"2456","DOI":"10.1167\/iovs.07-1325","article-title":"BDNF preserves the dendritic morphology of alpha and beta ganglion cells in the cat retina after optic nerve injury","volume":"49","author":"Weber","year":"2008","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.phrs.2012.03.002_bib0375","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.exer.2009.02.015","article-title":"Effects of different neurotrophic factors on the survival of retinal ganglion cells after a complete intraorbital nerve crush injury: a quantitative in vivo study","volume":"89","author":"Parrilla-Reverter","year":"2009","journal-title":"Exp Eye Res"},{"key":"10.1016\/j.phrs.2012.03.002_bib0380","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/j.exer.2011.02.001","article-title":"Brain derived neurotrophic factor maintains Brn3a expression in axotomized rat retinal ganglion cells","volume":"92","author":"S\u00e1nchez-Migall\u00f3n","year":"2011","journal-title":"Exp Eye Res"},{"key":"10.1016\/j.phrs.2012.03.002_bib0385","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.1002\/neu.480240907","article-title":"Different forms of the neurotrophin receptor trkB mRNA predominate in rat retina and optic nerve","volume":"24","author":"Jelsma","year":"1993","journal-title":"J Neurobiol"},{"key":"10.1016\/j.phrs.2012.03.002_bib0390","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/0304-3940(94)11123-Z","article-title":"Expression of brain-derived neurotrophic factor and of its functional receptor in neonatal and adult rat retina","volume":"183","author":"Perez","year":"1995","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.phrs.2012.03.002_bib0395","first-page":"927","article-title":"Neurotrophic factors cause activation of intracellular signaling pathways in M\u00fcller cells and other cells of the inner retina, but not photoreceptors","volume":"41","author":"Wahlin","year":"2000","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.phrs.2012.03.002_bib0400","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1016\/j.phrs.2010.12.017","article-title":"NGF and heart: is there a role in heart disease","volume":"63","author":"Govoni","year":"2011","journal-title":"Pharmacol Res"},{"key":"10.1016\/j.phrs.2012.03.002_bib0405","doi-asserted-by":"crossref","first-page":"46","DOI":"10.2174\/187152708783885174","article-title":"The biology of neurotrophins, signalling pathways, and functional peptide mimetics of neurotrophins and their receptors","volume":"7","author":"Skaper","year":"2008","journal-title":"CNS Neurol Disord Drug Targets"},{"key":"10.1016\/j.phrs.2012.03.002_bib0410","first-page":"764","article-title":"Obstructed axonal transport of BDNF and its receptor TrkB in experimental glaucoma","volume":"41","author":"Pease","year":"2000","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.phrs.2012.03.002_bib0415","first-page":"3460","article-title":"Retrograde axonal transport of BDNF in retinal ganglion cells is blocked by acute IOP elevation in rats","volume":"41","author":"Quigley","year":"2000","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.phrs.2012.03.002_bib0420","doi-asserted-by":"crossref","first-page":"7965","DOI":"10.1523\/JNEUROSCI.16-24-07965.1996","article-title":"Changing patterns of expression and subcellular localization of TrkB in the developing visual system","volume":"16","author":"Cabelli","year":"1996","journal-title":"J Neurosci"},{"key":"10.1016\/j.phrs.2012.03.002_bib0425","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1002\/cne.1075","article-title":"TrkB-like immunoreactivity is present on geniculocortical afferents in layer IV of kitten primary visual cortex","volume":"436","author":"Silver","year":"2001","journal-title":"J Comp Neurol"},{"key":"10.1016\/j.phrs.2012.03.002_bib0430","first-page":"2315","article-title":"Neurotrophin and neurotrophin receptor expression by cells of the human lamina cribrosa","volume":"42","author":"Lambert","year":"2001","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.phrs.2012.03.002_bib0435","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1167\/iovs.09-3740","article-title":"Combined application of BDNF to the eye and brain enhances ganglion cell survival and function in the cat after optic nerve injury","volume":"51","author":"Weber","year":"2010","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.phrs.2012.03.002_bib0440","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1113\/jphysiol.1988.sp016951","article-title":"Responses mediated by excitatory amino acid receptors in solitary retinal ganglion cells from rat","volume":"396","author":"Aizenman","year":"1988","journal-title":"J Physiol"},{"key":"10.1016\/j.phrs.2012.03.002_bib0445","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1038\/sj.eye.6701967","article-title":"Glutamate excitotoxicity in glaucoma: throwing the baby out with the bathwater?","volume":"20","author":"Salt","year":"2006","journal-title":"Eye (Lond)"},{"key":"10.1016\/j.phrs.2012.03.002_bib0450","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1167\/iovs.05-0754","article-title":"Assessment of neuroprotective effects of glutamate modulation on glaucoma-related retinal ganglion cell apoptosis in vivo","volume":"47","author":"Guo","year":"2006","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.phrs.2012.03.002_bib0455","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1001\/archopht.1996.01100130295012","article-title":"Elevated glutamate levels in the vitreous body of humans and monkeys with glaucoma","volume":"114","author":"Dreyer","year":"1996","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.phrs.2012.03.002_bib0460","first-page":"1618","article-title":"Chronic low-dose glutamate is toxic to retinal ganglion cells. Toxicity blocked by memantine","volume":"37","author":"Vorwerk","year":"1996","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.phrs.2012.03.002_bib0465","first-page":"1096","article-title":"Selective excitotoxic degeneration of adult pig retinal ganglion cells in vitro","volume":"42","author":"Luo","year":"2001","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.phrs.2012.03.002_bib0470","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1385\/MN:34:3:163","article-title":"N-methyl-d-aspartate receptors in the retina","volume":"34","author":"Shen","year":"2006","journal-title":"Mol Neurobiol"},{"key":"10.1016\/j.phrs.2012.03.002_bib0475","article-title":"The molecular basis of retinal ganglion cell death in glaucoma","author":"Almasieh","year":"2011","journal-title":"Prog Retin Eye Res"},{"key":"10.1016\/j.phrs.2012.03.002_bib0480","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1001\/archopht.1994.01090130047015","article-title":"The nerve of glaucoma!","volume":"112","author":"Schumer","year":"1994","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.phrs.2012.03.002_bib0485","doi-asserted-by":"crossref","first-page":"942","DOI":"10.1097\/00001756-199504190-00029","article-title":"Transcriptional or translational inhibition blocks low dose NMDA-mediated cell death","volume":"6","author":"Dreyer","year":"1995","journal-title":"Neuroreport"},{"key":"10.1016\/j.phrs.2012.03.002_bib0490","doi-asserted-by":"crossref","first-page":"1763","DOI":"10.1172\/JCI30178","article-title":"The potential role of glutamate transporters in the pathogenesis of normal tension glaucoma","volume":"117","author":"Harada","year":"2007","journal-title":"J Clin Invest"},{"key":"10.1016\/j.phrs.2012.03.002_bib0495","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.mrrev.2005.11.001","article-title":"The role of oxidative stress in glaucoma","volume":"612","author":"Izzotti","year":"2006","journal-title":"Mutat Res"},{"key":"10.1016\/j.phrs.2012.03.002_bib0500","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.2353\/ajpath.2008.070730","article-title":"Retinal dysfunction and progressive retinal cell death in SOD1-deficient mice","volume":"172","author":"Hashizume","year":"2008","journal-title":"Am J Pathol"},{"key":"10.1016\/j.phrs.2012.03.002_bib0505","doi-asserted-by":"crossref","first-page":"4143","DOI":"10.1167\/iovs.10-6294","article-title":"Retinal ganglion cell loss in superoxide dismutase 1-deficiency","volume":"52","author":"Yuki","year":"2011","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.phrs.2012.03.002_bib0510","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1007\/s12035-010-8143-3","article-title":"(Hsp 27) expression and neuroprotection in the retina","volume":"42","author":"O\u2019Reilly","year":"2010","journal-title":"Mol. Neurobiol"},{"key":"10.1016\/j.phrs.2012.03.002_bib0515","doi-asserted-by":"crossref","first-page":"12085","DOI":"10.1523\/JNEUROSCI.3200-08.2008","article-title":"Induced autoimmunity to heat shock proteins elicits glaucomatous loss of retinal ganglion cell neurons via activated T-cell-derived Fas-ligand","volume":"28","author":"Wax","year":"2008","journal-title":"J Neurosci"},{"key":"10.1016\/j.phrs.2012.03.002_bib0520","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1055\/s-0031-1273355","article-title":"Autoimmunity and glaucoma","volume":"228","author":"Grus","year":"2011","journal-title":"Klin Monbl Augenheilkd"},{"key":"10.1016\/j.phrs.2012.03.002_bib0525","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1097\/00055735-200404000-00003","article-title":"The immune system and glaucoma","volume":"15","author":"Tezel","year":"2004","journal-title":"Curr Opin Ophthalmol"},{"key":"10.1016\/j.phrs.2012.03.002_bib0530","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1038\/cdd.2011.88","article-title":"Autophagy promotes survival of retinal ganglion cells after optic nerve axotomy in mice","volume":"19","author":"Rodr\u00edguez-Muela","year":"2012","journal-title":"Cell Death Differ"},{"key":"10.1016\/j.phrs.2012.03.002_bib0535","doi-asserted-by":"crossref","first-page":"1481","DOI":"10.1084\/jem.185.8.1481","article-title":"Intracellular adenosine triphosphate (ATP) concentration: a switch in the decision between apoptosis and necrosis","volume":"185","author":"Leist","year":"1997","journal-title":"J Exp Med"},{"key":"10.1016\/j.phrs.2012.03.002_bib0540","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/0014-5793(95)01431-4","article-title":"Control of apoptosis by the cellular ATP level","volume":"378","author":"Richter","year":"1996","journal-title":"FEBS Lett"},{"key":"10.1016\/j.phrs.2012.03.002_bib0545","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1016\/j.cell.2010.02.016","article-title":"Mechanisms underlying inflammation in neurodegeneration","volume":"140","author":"Glass","year":"2010","journal-title":"Cell"},{"key":"10.1016\/j.phrs.2012.03.002_bib0550","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.arr.2011.12.004","article-title":"Pentraxins and Alzheimer's disease: at the interface between biomarkers and pharmacological targets","volume":"11","author":"Osera","year":"2012","journal-title":"Ageing Res Rev"},{"key":"10.1016\/j.phrs.2012.03.002_bib0555","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1002\/jnr.10713","article-title":"Characterization of activated retinal microglia following optic axotomy","volume":"73","author":"Zhang","year":"2003","journal-title":"J Neurosci Res"},{"key":"10.1016\/j.phrs.2012.03.002_bib0560","first-page":"2969","article-title":"Effect of intraocular pressure on optic disc topography, electroretinography, and axonal loss in a chronic pressure-induced rat model of optic nerve damage","volume":"43","author":"Chauhan","year":"2002","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.phrs.2012.03.002_bib0565","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1002\/glia.20962","article-title":"Glaucomatous optic nerve injury involves early astrocyte reactivity and late oligodendrocyte loss","volume":"58","author":"Son","year":"2010","journal-title":"Glia"},{"key":"10.1016\/j.phrs.2012.03.002_bib0570","doi-asserted-by":"crossref","first-page":"1050","DOI":"10.1001\/archopht.117.8.1050","article-title":"Microglia in the optic nerve head and the region of parapapillary chorioretinal atrophy in glaucoma","volume":"117","author":"Neufeld","year":"1999","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.phrs.2012.03.002_bib0575","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1002\/jnr.1104","article-title":"Activated microglia in the human glaucomatous optic nerve head","volume":"64","author":"Yuan","year":"2001","journal-title":"J Neurosci Res"},{"key":"10.1016\/j.phrs.2012.03.002_bib0580","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1002\/cne.22516","article-title":"Early microglia activation in a mouse model of chronic glaucoma","volume":"519","author":"Bosco","year":"2011","journal-title":"J Comp Neurol"},{"key":"10.1016\/j.phrs.2012.03.002_bib0585","doi-asserted-by":"crossref","first-page":"1437","DOI":"10.1167\/iovs.07-1337","article-title":"Reduced retina microglial activation and improved optic nerve integrity with minocycline treatment in the DBA\/2J mouse model of glaucoma","volume":"49","author":"Bosco","year":"2008","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.phrs.2012.03.002_bib0590","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/0039-6257(81)90061-8","article-title":"Optic nerve damage in glaucoma","volume":"26","author":"Minckler","year":"1981","journal-title":"Surv Ophthalmol"},{"key":"10.1016\/j.phrs.2012.03.002_bib0595","first-page":"431","article-title":"Chronology of optic nerve head and retinal responses to elevated intraocular pressure","volume":"41","author":"Johnson","year":"2000","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.phrs.2012.03.002_bib0600","doi-asserted-by":"crossref","first-page":"942","DOI":"10.1002\/glia.20516","article-title":"Reactive nonproliferative gliosis predominates in a chronic mouse model of glaucoma","volume":"55","author":"Inman","year":"2007","journal-title":"Glia"},{"key":"10.1016\/j.phrs.2012.03.002_bib0605","doi-asserted-by":"crossref","first-page":"1176","DOI":"10.1073\/pnas.1013965108","article-title":"Myelination transition zone astrocytes are constitutively phagocytic and have synuclein dependent reactivity in glaucoma","volume":"108","author":"Nguyen","year":"2011","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.phrs.2012.03.002_bib0610","doi-asserted-by":"crossref","first-page":"2271","DOI":"10.1016\/j.ophtha.2009.06.042","article-title":"Natural history of open-angle glaucoma","volume":"116","author":"Heijl","year":"2009","journal-title":"Ophthalmology"},{"key":"10.1016\/j.phrs.2012.03.002_bib0615","first-page":"RA252","article-title":"Future possibilities in glaucoma therapy","volume":"16","author":"Wierzbowska","year":"2010","journal-title":"Med Sci Monit"},{"key":"10.1016\/j.phrs.2012.03.002_bib0620","doi-asserted-by":"crossref","first-page":"1268","DOI":"10.1001\/archopht.120.10.1268","article-title":"Reduction of intraocular pressure and glaucoma progression: results from the Early Manifest Glaucoma Trial","volume":"120","author":"Heijl","year":"2002","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.phrs.2012.03.002_bib0625","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1001\/archopht.122.6.813","article-title":"The Ocular Hypertension Treatment Study: topical medication delays or prevents primary open-angle glaucoma in African American individuals","volume":"122","author":"Higginbotham","year":"2004","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.phrs.2012.03.002_bib0630","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1001\/archopht.120.6.701","article-title":"The Ocular Hypertension Treatment Study: a randomized trial determines that topical ocular hypotensive medication delays or prevents the onset of primary open-angle glaucoma","volume":"120","author":"Kass","year":"2002","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.phrs.2012.03.002_bib0635","doi-asserted-by":"crossref","first-page":"1965","DOI":"10.1016\/j.ophtha.2007.03.016","article-title":"Predictors of long-term progression in the early manifest glaucoma trial","volume":"114","author":"Leske","year":"2007","journal-title":"Ophthalmology"},{"key":"10.1016\/j.phrs.2012.03.002_bib0640","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1001\/archopht.121.1.48","article-title":"Factors for glaucoma progression and the effect of treatment: the early manifest glaucoma trial","volume":"121","author":"Leske","year":"2003","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.phrs.2012.03.002_bib0645","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1016\/S0002-9394(98)00272-4","article-title":"The effectiveness of intraocular pressure reduction in the treatment of normal-tension glaucoma","volume":"126","year":"1998","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.phrs.2012.03.002_bib0650","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.preteyeres.2009.08.002","article-title":"Is the medication used to achieve the target intraocular pressure in glaucoma therapy of relevance?\u2014an exemplary analysis on the basis of two beta-blockers","volume":"29","author":"Grieshaber","year":"2010","journal-title":"Prog Retin Eye Res"},{"key":"10.1016\/j.phrs.2012.03.002_bib0655","first-page":"253","article-title":"Visual field progression in open-angle glaucoma patients presenting with monocular field loss","volume":"81","author":"Harbin","year":"1976","journal-title":"Trans Sect Ophthalmol Am Acad Ophthalmol Otolaryngol"},{"key":"10.1016\/j.phrs.2012.03.002_bib0660","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1177\/112067219700700409","article-title":"Risk factors in ocular hypertension","volume":"7","author":"Georgopoulos","year":"1997","journal-title":"Eur J Ophthalmol"},{"key":"10.1016\/j.phrs.2012.03.002_bib0665","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1111\/j.1600-0420.1997.tb00391.x","article-title":"Neuroprotection of the optic nerve in glaucoma","volume":"75","author":"Caprioli","year":"1997","journal-title":"Acta Ophthalmol Scand"},{"key":"10.1016\/j.phrs.2012.03.002_bib0670","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1016\/S0161-6420(01)01009-0","article-title":"Long-term follow-up of visual field progression after trabeculectomy in progressive normal-tension glaucoma","volume":"109","author":"Shigeeda","year":"2002","journal-title":"Ophthalmology"},{"key":"10.1016\/j.phrs.2012.03.002_bib0675","doi-asserted-by":"crossref","DOI":"10.1016\/j.ajo.2009.03.029","article-title":"Neuroprotection: extrapolating from neurologic diseases to the eye","volume":"148","author":"Danesh-Meyer","year":"2009","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.phrs.2012.03.002_bib0680","doi-asserted-by":"crossref","first-page":"2109","DOI":"10.1097\/00001756-200211150-00023","article-title":"Citicoline has a protective effect on damaged retinal ganglion cells in mouse culture retina","volume":"13","author":"Oshitari","year":"2002","journal-title":"Neuroreport"},{"key":"10.1016\/j.phrs.2012.03.002_bib0685","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.brainres.2010.05.073","article-title":"Effect of neurotrophic factors on neuronal apoptosis and neurite regeneration in cultured rat retinas exposed to high glucose","volume":"1346","author":"Oshitari","year":"2010","journal-title":"Brain Res"},{"key":"10.1016\/j.phrs.2012.03.002_bib0690","doi-asserted-by":"crossref","first-page":"946","DOI":"10.1046\/j.1471-4159.1998.71030946.x","article-title":"Role of caspases in N-methyl-d-aspartate-induced apoptosis in cerebrocortical neurons","volume":"71","author":"Tenneti","year":"1998","journal-title":"J Neurochem"},{"key":"10.1016\/j.phrs.2012.03.002_bib0695","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1097\/OPX.0b013e31817841e5","article-title":"Neuroprotection in glaucoma: drug-based approaches","volume":"85","author":"Cheung","year":"2008","journal-title":"Optom Vis Sci"},{"key":"10.1016\/j.phrs.2012.03.002_bib0700","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/S0006-8993(98)00212-1","article-title":"MK801-a neuroprotectant in rat hypertensive eyes","volume":"792","author":"Chaudhary","year":"1998","journal-title":"Brain Res"},{"key":"10.1016\/j.phrs.2012.03.002_bib0705","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3341\/kjo.2002.16.1.1","article-title":"Neuroprotective effect of memantine in a rabbit model of optic nerve ischemia","volume":"16","author":"Kim","year":"2002","journal-title":"Korean J Ophthalmol"},{"key":"10.1016\/j.phrs.2012.03.002_bib0710","doi-asserted-by":"crossref","first-page":"725","DOI":"10.2165\/00003495-200767050-00006","article-title":"Pharmacological neuroprotection for glaucoma","volume":"67","author":"Chidlow","year":"2007","journal-title":"Drugs"},{"key":"10.1016\/j.phrs.2012.03.002_bib0715","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1111\/j.1755-3768.2008.01459.x","article-title":"Recent clinical findings with memantine should not mean that the idea of neuroprotection in glaucoma is abandoned","volume":"87","author":"Osborne","year":"2009","journal-title":"Acta Ophthalmol"},{"key":"10.1016\/j.phrs.2012.03.002_bib0720","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1038\/nature03180","article-title":"Beta-lactam antibiotics offer neuroprotection by increasing glutamate transporter expression","volume":"433","author":"Rothstein","year":"2005","journal-title":"Nature"},{"key":"10.1016\/j.phrs.2012.03.002_bib0725","doi-asserted-by":"crossref","first-page":"S102","DOI":"10.4103\/0301-4738.73700","article-title":"Neuroprotection in glaucoma","volume":"59","author":"Vasudevan","year":"2011","journal-title":"Indian J Ophthalmol"},{"key":"10.1016\/j.phrs.2012.03.002_bib0730","doi-asserted-by":"crossref","first-page":"S25","DOI":"10.1016\/S0039-6257(03)00005-5","article-title":"Hypothesis for a common basis for neuroprotection in glaucoma and Alzheimer's disease: anti-apoptosis by alpha-2-adrenergic receptor activation","volume":"48","author":"Tatton","year":"2003","journal-title":"Surv Ophthalmol"},{"issue":"1","key":"10.1016\/j.phrs.2012.03.002_bib0735","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1186\/1750-1326-6-4","article-title":"Brimonidine prevents axonal and somatic degeneration of retinal ganglion cell neurons","volume":"6","author":"Lambert","year":"2011","journal-title":"Mol Neurodegener"},{"key":"10.1016\/j.phrs.2012.03.002_bib0740","doi-asserted-by":"crossref","first-page":"3825","DOI":"10.1167\/iovs.05-0392","article-title":"Ischemia results 3 months later in altered ERG, degeneration of inner layers, and deafferented tectum: neuroprotection with brimonidine","volume":"46","author":"Mayor-Torroglosa","year":"2005","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.phrs.2012.03.002_bib0745","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1007\/s00417-005-0102-8","article-title":"Efficacy and tolerability of 0.2% brimonidine tartrate for the treatment of acute non-arteritic anterior ischemic optic neuropathy (NAION): a 3-month, double-masked, randomised, placebo-controlled trial","volume":"244","author":"Wilhelm","year":"2006","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"10.1016\/j.phrs.2012.03.002_bib0750","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1016\/j.ajo.2010.09.026","article-title":"A randomized trial of brimonidine versus timolol in preserving visual function: results from the Low-Pressure Glaucoma Treatment Study","volume":"151","author":"Krupin","year":"2011","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.phrs.2012.03.002_bib0755","doi-asserted-by":"crossref","first-page":"4656","DOI":"10.1523\/JNEUROSCI.18-12-04656.1998","article-title":"Inhibition of CPP32-like proteases rescues axotomized retinal ganglion cells from secondary cell death in vivo","volume":"18","author":"Kermer","year":"1998","journal-title":"J Neurosci"},{"key":"10.1016\/j.phrs.2012.03.002_bib0760","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/S0014-5793(99)00747-4","article-title":"Activation of caspase-3 in axotomized rat retinal ganglion cells in vivo","volume":"453","author":"Kermer","year":"1999","journal-title":"FEBS Lett"},{"key":"10.1016\/j.phrs.2012.03.002_bib0765","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/S0169-328X(99)00032-7","article-title":"Caspase inhibitors block the retinal ganglion cell death following optic nerve transection","volume":"67","author":"Chaudhary","year":"1999","journal-title":"Brain Res Mol Brain Res"},{"key":"10.1016\/j.phrs.2012.03.002_bib0770","doi-asserted-by":"crossref","first-page":"295","DOI":"10.2174\/187152708784936644","article-title":"Neuroprotection in glaucoma using calpain-1 inhibitors: regional differences in calpain-1 activity in the trabecular meshwork, optic nerve and implications for therapeutics","volume":"7","author":"Govindarajan","year":"2008","journal-title":"CNS Neurol Disord Drug Targets"},{"key":"10.1016\/j.phrs.2012.03.002_bib0775","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1111\/j.1442-9071.2008.01740.x","article-title":"Bioenergetic-based neuroprotection and glaucoma","volume":"36","author":"Schober","year":"2008","journal-title":"Clin Experiment Ophthalmol"},{"key":"10.1016\/j.phrs.2012.03.002_bib0780","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1016\/j.neuint.2007.09.012","article-title":"Nicotinamide attenuates retinal ischemia and light insults to neurones","volume":"52","author":"Ji","year":"2008","journal-title":"Neurochem Int"},{"key":"10.1016\/j.phrs.2012.03.002_bib0785","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/S0074-7742(07)82022-8","article-title":"Retinal damage caused by high intraocular pressure-induced transient ischemia is prevented by coenzyme Q10 in rat","volume":"82","author":"Nucci","year":"2007","journal-title":"Int Rev Neurobiol"},{"key":"10.1016\/j.phrs.2012.03.002_bib0790","doi-asserted-by":"crossref","first-page":"S40","DOI":"10.1161\/STROKEAHA.110.606509","article-title":"Citicoline in vascular cognitive impairment and vascular dementia after stroke","volume":"42","author":"Alvarez-Sab\u00edn","year":"2011","journal-title":"Stroke"},{"key":"10.1016\/j.phrs.2012.03.002_bib0795","doi-asserted-by":"crossref","first-page":"S36","DOI":"10.1161\/STROKEAHA.110.605568","article-title":"Citicoline preclinical and clinical update 2009\u20132010","volume":"42","author":"D\u00e1valos","year":"2011","journal-title":"Stroke"},{"key":"10.1016\/j.phrs.2012.03.002_bib0800","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1002\/jnr.10129","article-title":"Pharmacodynamics of citicoline relevant to the treatment of glaucoma","volume":"67","author":"Grieb","year":"2002","journal-title":"J Neurosci Res"},{"key":"10.1016\/j.phrs.2012.03.002_bib0805","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1080\/01616412.1995.11740327","article-title":"Citicoline (CDP-choline): mechanisms of action and effects in ischemic brain injury","volume":"17","author":"D\u2019Orlando","year":"1995","journal-title":"Neurol Res"},{"key":"10.1016\/j.phrs.2012.03.002_bib0810","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1023\/A:1027359727263","article-title":"Lipid metabolism in photoreceptor membranes: regulation and mechanisms","volume":"22","author":"Giusto","year":"1997","journal-title":"Neurochem Res"},{"key":"10.1016\/j.phrs.2012.03.002_bib0815","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1046\/j.1471-4159.1997.69030889.x","article-title":"Phospholipase A2 and its role in brain tissue","volume":"69","author":"Farooqui","year":"1997","journal-title":"J Neurochem"},{"key":"10.1016\/j.phrs.2012.03.002_bib0820","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1161\/01.STR.29.3.705","article-title":"Calcium in ischemic cell death","volume":"29","author":"Kristi\u00e1n","year":"1998","journal-title":"Stroke"},{"key":"10.1016\/j.phrs.2012.03.002_bib0825","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1046\/j.1471-4159.1995.65020889.x","article-title":"Evidence that 5\u2032-cytidinediphosphocholine can affect brain phospholipid composition by increasing choline and cytidine plasma levels","volume":"65","author":"L\u00f3pez-Coviella","year":"1995","journal-title":"J Neurochem"},{"key":"10.1016\/j.phrs.2012.03.002_bib0830","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/S0304-3940(00)00906-X","article-title":"Choline plus cytidine stimulate phospholipid production, and the expression and secretion of amyloid precursor protein in rat PC12 cells","volume":"283","author":"Wang","year":"2000","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.phrs.2012.03.002_bib0835","doi-asserted-by":"crossref","first-page":"3697","DOI":"10.1016\/0006-2952(87)90022-0","article-title":"Effects of CDP-choline on phospholipase A2 and cholinephosphotransferase activities following a cryogenic brain injury in the rabbit","volume":"36","author":"Arrigoni","year":"1987","journal-title":"Biochem Pharmacol"},{"key":"10.1016\/j.phrs.2012.03.002_bib0840","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1016\/S0006-8993(00)03280-7","article-title":"Does CDP-choline modulate phospholipase activities after transient forebrain ischemia","volume":"893","author":"Rao","year":"2001","journal-title":"Brain Res"},{"key":"10.1016\/j.phrs.2012.03.002_bib0845","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1007\/BF00238608","article-title":"Electroretinographic responses to alternating gratings in the cat","volume":"48","author":"Maffei","year":"1982","journal-title":"Exp Brain Res"},{"key":"10.1016\/j.phrs.2012.03.002_bib0850","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1038\/eye.1997.231","article-title":"The pattern electroretinogram in anterior visual pathway dysfunction and its relationship to the pattern visual evoked potential: a personal clinical review of 743 eyes","volume":"11","author":"Holder","year":"1997","journal-title":"Eye (Lond)"},{"key":"10.1016\/j.phrs.2012.03.002_bib0855","first-page":"2520","article-title":"Correlation between morphological and functional retinal impairment in multiple sclerosis patients","volume":"40","author":"Parisi","year":"1999","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.phrs.2012.03.002_bib0860","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/0013-4694(93)90157-Q","article-title":"Recommended standards for electroretinograms and visual evoked potentials. Report of an IFCN committee","volume":"87","author":"Celesia","year":"1993","journal-title":"Electroencephalogr Clin Neurophysiol"},{"key":"10.1016\/j.phrs.2012.03.002_bib0865","doi-asserted-by":"crossref","first-page":"1126","DOI":"10.1016\/S0161-6420(99)90269-5","article-title":"Cytidine-5\u2032-diphosphocholine (citicoline) improves retinal and cortical responses in patients with glaucoma","volume":"106","author":"Parisi","year":"1999","journal-title":"Ophthalmology"},{"key":"10.1016\/j.phrs.2012.03.002_bib0870","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1007\/s10633-005-7348-7","article-title":"Electrophysiological assessment of glaucomatous visual dysfunction during treatment with cytidine-5\u2032-diphosphocholine (citicoline): a study of 8 years of follow-up","volume":"110","author":"Parisi","year":"2005","journal-title":"Doc Ophthalmol"},{"key":"10.1016\/j.phrs.2012.03.002_bib0875","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/S0079-6123(08)01137-0","article-title":"Evidence of the neuroprotective role of citicoline in glaucoma patients","volume":"173","author":"Parisi","year":"2008","journal-title":"Prog Brain Res"},{"key":"10.1016\/j.phrs.2012.03.002_bib0880","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1007\/BF00177654","article-title":"Effect of citicoline on visual acuity in amblyopia: preliminary results","volume":"233","author":"Campos","year":"1995","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"10.1016\/j.phrs.2012.03.002_bib0885","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1076\/ceyr.17.2.141.5606","article-title":"Cytidine-5\u2032-diphosphocholine improves visual acuity, contrast sensitivity and visually-evoked potentials of amblyopic subjects","volume":"17","author":"Porciatti","year":"1998","journal-title":"Curr Eye Res"},{"key":"10.1016\/j.phrs.2012.03.002_bib0890","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/0306-3623(90)90598-G","article-title":"Changes in brain biogenic monoamines induced by the nootropic drugs adafenoxate and meclofenoxate and by citicholine (experiments on rats)","volume":"21","author":"Petkov","year":"1990","journal-title":"Gen Pharmacol"},{"key":"10.1016\/j.phrs.2012.03.002_bib0895","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1159\/000063658","article-title":"Citicoline treatment increases retinal dopamine content in rabbits","volume":"34","author":"Rejdak","year":"2002","journal-title":"Ophthalmic Res"},{"key":"10.1016\/j.phrs.2012.03.002_bib0900","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1007\/BF02172892","article-title":"Effect of levodopa on the human pattern electroretinogram and pattern visual evoked potentials","volume":"227","author":"Gottlob","year":"1989","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"10.1016\/j.phrs.2012.03.002_bib0905","first-page":"307","article-title":"Physiological and pharmacological influences on dopaminergic receptors in the retina","volume":"16","author":"Spano","year":"1977","journal-title":"Adv Biochem Psychopharmacol"},{"key":"10.1016\/j.phrs.2012.03.002_bib0910","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1016\/0006-8993(77)90695-3","article-title":"Dopamine receptor sensitivity in brain and retina of rats during aging","volume":"138","author":"Govoni","year":"1977","journal-title":"Brain Res"},{"key":"10.1016\/j.phrs.2012.03.002_bib0915","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/0197-0186(95)00038-A","article-title":"Are there dopaminergic ganglion cells in the mammalian retina","volume":"27","author":"Simon","year":"1995","journal-title":"Neurochem Int"},{"key":"10.1016\/j.phrs.2012.03.002_bib0920","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/0197-0186(95)00038-A","article-title":"Beta-adrenergic receptors in ciliary processes of the rabbit","volume":"19","author":"Bromberg","year":"1980","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.phrs.2012.03.002_bib0925","first-page":"798","article-title":"Human ciliary process adrenergic receptor: pharmacological characterization","volume":"21","author":"Nathanson","year":"1981","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.phrs.2012.03.002_bib0930","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/j.ophtha.2005.10.044","article-title":"Clinical ability of pattern electroretinograms and visual evoked potentials in detecting visual dysfunction in ocular hypertension and glaucoma","volume":"113","author":"Parisi","year":"2006","journal-title":"Ophthalmology"},{"key":"10.1016\/j.phrs.2012.03.002_bib0935","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/S0002-9394(14)71283-8","article-title":"Lateral geniculate nucleus in glaucoma","volume":"116","author":"Chaturvedi","year":"1993","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.phrs.2012.03.002_bib0940","first-page":"1370","article-title":"Experimental glaucoma and cell size, density, and number in the primate lateral geniculate nucleus","volume":"41","author":"Weber","year":"2000","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.phrs.2012.03.002_bib0945","first-page":"3216","article-title":"Atrophy of relay neurons in magno- and parvocellular layers in the lateral geniculate nucleus in experimental glaucoma","volume":"42","author":"Y\u00fccel","year":"2001","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.phrs.2012.03.002_bib0950","doi-asserted-by":"crossref","first-page":"940","DOI":"10.1007\/BF01190471","article-title":"Regenerated synapses persist in the superior colliculus after the regrowth of retinal ganglion cell axons","volume":"20","author":"Vidal-Sanz","year":"1991","journal-title":"J Neurocytol"},{"key":"10.1016\/j.phrs.2012.03.002_bib0955","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1007\/BF01190471","article-title":"Reinnervation of the pretectum in adult rats by regenerated retinal ganglion cell axons: anatomical and functional studies","volume":"137","author":"Vidal-Sanz","year":"2002","journal-title":"Prog Brain Res"},{"key":"10.1016\/j.phrs.2012.03.002_bib0960","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/S0079-6123(02)37035-3","article-title":"Retinal ganglion cells lose trophic responsiveness after axotomy","volume":"23","author":"Shen","year":"1999","journal-title":"Neuron"},{"key":"10.1016\/j.phrs.2012.03.002_bib0965","doi-asserted-by":"crossref","first-page":"2578","DOI":"10.1016\/S0896-6273(00)80780-1","article-title":"Functional and morphological effects of laser-induced ocular hypertension in retinas of adult albino Swiss mice","volume":"15","author":"Salinas-Navarro","year":"2009","journal-title":"Mol Vis"},{"key":"10.1016\/j.phrs.2012.03.002_bib0970","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.exer.2009.10.003","article-title":"Ocular hypertension impairs optic nerve axonal transport leading to progressive retinal ganglion cell degeneration","volume":"90","author":"Salinas-Navarro","year":"2010","journal-title":"Exp Eye Res"},{"key":"10.1016\/j.phrs.2012.03.002_bib0975","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/j.exer.2009.10.003","article-title":"Changes in the inner and outer retinal layers after acute increase of the intraocular pressure in adult albino Swiss mice","volume":"91","author":"Cuenca","year":"2010","journal-title":"Exp Eye Res"},{"key":"10.1016\/j.phrs.2012.03.002_bib0980","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.exer.2010.05.020","article-title":"Understanding glaucomatous damage: anatomical and functional data from ocular hypertensive rodent retinas","volume":"31","author":"Vidal-Sanz","year":"2012","journal-title":"Prog Retin Eye Res"},{"key":"10.1016\/j.phrs.2012.03.002_bib0985","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1016\/j.preteyeres.2011.08.001","article-title":"Specific amacrine cell changes in an induced mouse model of glaucoma","volume":"39","author":"Gunn","year":"2011","journal-title":"Clin Experiment Ophthalmol"},{"key":"10.1016\/j.phrs.2012.03.002_bib0990","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1111\/j.1442-9071.2010.02488.x","article-title":"Reaction of M\u00fcller cells in an experimental rat model of increased intraocular pressure following timolol, latanoprost and brimonidine","volume":"82","author":"Vidal","year":"2010","journal-title":"Brain Res Bull"},{"key":"10.1016\/j.phrs.2012.03.002_bib0995","doi-asserted-by":"crossref","first-page":"2696","DOI":"10.1016\/j.brainresbull.2010.02.011","article-title":"Immunohistochemical changes in rat retinas at various time periods of elevated intraocular pressure","volume":"15","author":"Hernandez","year":"2009","journal-title":"Mol Vis"},{"key":"10.1016\/j.phrs.2012.03.002_bib1000","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1007\/s10571-007-9155-z","article-title":"Up-regulated endogenous erythropoietin\/erythropoietin receptor system and exogenous erythropoietin rescue retinal ganglion cells after chronic ocular hypertension","volume":"28","author":"Fu","year":"2008","journal-title":"Cell Mol Neurobiol"},{"key":"10.1016\/j.phrs.2012.03.002_bib1005","doi-asserted-by":"crossref","first-page":"1272","DOI":"10.1007\/s10571-007-9155-z","article-title":"Decrease of cone opsin mRNA in experimental ocular hypertension","volume":"12","author":"Pelzel","year":"2006","journal-title":"Mol Vis"},{"key":"10.1016\/j.phrs.2012.03.002_bib1010","first-page":"71","article-title":"Specific expression of E-Tmod (Tmod1) in horizontal cells: implications in neuronal cell mechanics and glaucomatous retina","volume":"6","author":"Yao","year":"2009","journal-title":"Mol Cell Biomech"},{"key":"10.1016\/j.phrs.2012.03.002_bib1015","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1083\/jcb.200506099","article-title":"Retinal ganglion cell degeneration is topological but not cell type specific in DBA\/2J mice","volume":"171","author":"Jakobs","year":"2005","journal-title":"J Cell Biol"},{"key":"10.1016\/j.phrs.2012.03.002_bib1020","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1083\/jcb.200506099","article-title":"Evidence for glaucoma-induced horizontal cell alterations in the human retina","volume":"5","author":"Janssen","year":"1996","journal-title":"Ger J Ophthalmol"},{"key":"10.1016\/j.phrs.2012.03.002_bib1025","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1001\/archopht.118.2.235","article-title":"Swelling and loss of photoreceptors in chronic human and experimental glaucomas","volume":"118","author":"Nork","year":"2000","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.phrs.2012.03.002_bib1030","doi-asserted-by":"crossref","first-page":"1216","DOI":"10.1167\/iovs.09-3409","article-title":"Electrophysiological evidence of early functional damage in glaucoma and ocular hypertension","volume":"51","author":"North","year":"2010","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.phrs.2012.03.002_bib1035","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1167\/iovs.09-3409","article-title":"Mapping of macular substructures with optical coherence tomography for glaucoma diagnosis","volume":"115","author":"Tan","year":"2008","journal-title":"Ophthalmology"},{"key":"10.1016\/j.phrs.2012.03.002_bib1040","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/j.ophtha.2007.08.011","article-title":"Effects of axotomy and intraocular administration of NT-4, NT-3, and brain-derived neurotrophic factor on the survival of adult rat retinal ganglion cells. A quantitative in vivo study","volume":"37","author":"Peinado-Ram\u00f3n","year":"1996","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.phrs.2012.03.002_bib1045","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1097\/IJG.0b013e3181d787e5","article-title":"Ocular application of nerve growth factor protects degenerating retinal ganglion cells in a rat model of glaucoma","volume":"20","author":"Colafrancesco","year":"2011","journal-title":"J Glaucoma"},{"key":"10.1016\/j.phrs.2012.03.002_bib1050","doi-asserted-by":"crossref","first-page":"2194","DOI":"10.1167\/iovs.08-3013","article-title":"Effect of CNTF on retinal ganglion cell survival in experimental glaucoma","volume":"50","author":"Pease","year":"2009","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.phrs.2012.03.002_bib1055","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1097\/IJG.0b013e3181d787e5","article-title":"Neuroprotective effect of citicoline on retinal cell damage induced by kainic acid in rats","volume":"19","author":"Han","year":"2005","journal-title":"Korean J Ophthalmol"},{"key":"10.1016\/j.phrs.2012.03.002_bib1060","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1167\/iovs.08-3013","article-title":"Enhanced survival and regeneration of axotomized retinal ganglion cells by a mixture of herbal extracts","volume":"19","author":"Cheung","year":"2002","journal-title":"J Neurotrauma"},{"key":"10.1016\/j.phrs.2012.03.002_bib1065","doi-asserted-by":"crossref","first-page":"323","DOI":"10.3341\/kjo.2005.19.3.219","article-title":"Short-term effects of Ginkgo Biloba extract on peripapillary retinal blood flow in normal tension glaucoma","volume":"25","author":"Park","year":"2011","journal-title":"Korean J Ophthalmol"},{"key":"10.1016\/j.phrs.2012.03.002_bib1070","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1089\/089771502753594936","article-title":"Fatty acid use in glaucomatous optic neuropathy treatment","volume":"227","author":"Cellini","year":"1998","journal-title":"Acta Ophthalmol Scand Suppl"},{"key":"10.1016\/j.phrs.2012.03.002_bib1075","doi-asserted-by":"crossref","first-page":"243","DOI":"10.3341\/kjo.2011.25.5.323","article-title":"Transient ischemia of the retina results in altered retrograde axoplasmic transport: neuroprotection with brimonidine","volume":"178","author":"Lafuente L\u00f3pez-Herrera","year":"2002","journal-title":"Exp Neurol"},{"key":"10.1016\/j.phrs.2012.03.002_bib1080","first-page":"2849","article-title":"Neuroprotection of retinal ganglion cells by brimonidine in rats with laser-induced chronic ocular hypertension","volume":"42","author":"WoldeMussie","year":"2001","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.phrs.2012.03.002_bib1085","doi-asserted-by":"crossref","first-page":"5420","DOI":"10.1006\/exnr.2002.8043","article-title":"A key role for calpains in retinal ganglion cell death","volume":"48","author":"McKernan","year":"2007","journal-title":"Invest Ophthalmol Vis Sci"}],"container-title":["Pharmacological Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1043661812000424?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1043661812000424?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,4,21]],"date-time":"2024-04-21T15:21:42Z","timestamp":1713712902000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1043661812000424"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,7]]},"references-count":217,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012,7]]}},"alternative-id":["S1043661812000424"],"URL":"https:\/\/doi.org\/10.1016\/j.phrs.2012.03.002","relation":{},"ISSN":["1043-6618"],"issn-type":[{"value":"1043-6618","type":"print"}],"subject":[],"published":{"date-parts":[[2012,7]]}}}