{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T05:16:43Z","timestamp":1791091003166,"version":"4.1.0"},"reference-count":58,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2013,4,1]],"date-time":"2013-04-01T00:00:00Z","timestamp":1364774400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,4,1]],"date-time":"2013-04-01T00:00:00Z","timestamp":1364774400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2013,4,1]],"date-time":"2013-04-01T00:00:00Z","timestamp":1364774400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2013,4,1]],"date-time":"2013-04-01T00:00:00Z","timestamp":1364774400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2013,4,1]],"date-time":"2013-04-01T00:00:00Z","timestamp":1364774400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2013,4,1]],"date-time":"2013-04-01T00:00:00Z","timestamp":1364774400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2013,4,1]],"date-time":"2013-04-01T00:00:00Z","timestamp":1364774400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Pharmacological Research"],"published-print":{"date-parts":[[2013,4]]},"DOI":"10.1016\/j.phrs.2013.01.010","type":"journal-article","created":{"date-parts":[[2013,2,1]],"date-time":"2013-02-01T01:50:45Z","timestamp":1359683445000},"page":"147-154","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":26,"title":["Bradykinin modulates spontaneous nerve growth factor production and stretch-induced ATP release in human urothelium"],"prefix":"10.1016","volume":"70","author":[{"given":"Peter","family":"Ochodnick\u00fd","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martina B.","family":"Michel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan J.","family":"Butter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jai","family":"Seth","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jalesh N.","family":"Panicker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin C.","family":"Michel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.phrs.2013.01.010_bib0005","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1038\/sj.ki.5002439","article-title":"The uroepithelial-associated sensory web","volume":"72","author":"Apodaca","year":"2007","journal-title":"Kidney International"},{"key":"10.1016\/j.phrs.2013.01.010_bib0010","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1038\/ncpuro0672","article-title":"Mechanisms of disease: involvement of the urothelium in bladder dysfunction","volume":"4","author":"Birder","year":"2007","journal-title":"Nature Clinical Practice: Urology"},{"key":"10.1016\/j.phrs.2013.01.010_bib0015","doi-asserted-by":"crossref","first-page":"5670","DOI":"10.1523\/JNEUROSCI.21-15-05670.2001","article-title":"P2X3 knock-out mice reveal a major sensory role for urothelially released ATP","volume":"21","author":"Vlaskovska","year":"2001","journal-title":"Journal of Neuroscience"},{"key":"10.1016\/j.phrs.2013.01.010_bib0020","first-page":"F226","article-title":"Adrenergic- and capsaicin-evoked nitric oxide release from urothelium and afferent nerves in urinary bladder","volume":"275","author":"Birder","year":"1998","journal-title":"American Journal of Physiology"},{"key":"10.1016\/j.phrs.2013.01.010_bib0025","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1016\/j.urology.2005.08.014","article-title":"Non-neuronal cholinergic system in human bladder urothelium","volume":"67","author":"Yoshida","year":"2006","journal-title":"Urology"},{"issue":"Pt 2","key":"10.1016\/j.phrs.2013.01.010_bib0030","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1111\/j.1469-7793.1997.503bb.x","article-title":"ATP is released from rabbit urinary bladder epithelial cells by hydrostatic pressure changes \u2013 a possible sensory mechanism?","volume":"505","author":"Ferguson","year":"1997","journal-title":"Journal of Physiology"},{"key":"10.1016\/j.phrs.2013.01.010_bib0035","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.1016\/j.eururo.2009.11.042","article-title":"In vitro release of adenosine triphosphate from the urothelium of human bladders with detrusor overactivity, both neurogenic and idiopathic","volume":"57","author":"Kumar","year":"2010","journal-title":"European Urology"},{"key":"10.1016\/j.phrs.2013.01.010_bib0040","doi-asserted-by":"crossref","first-page":"1951","DOI":"10.1016\/S0022-5347(05)65726-6","article-title":"Augmented stretch activated adenosine triphosphate release from bladder uroepithelial cells in patients with interstitial cystitis","volume":"166","author":"Sun","year":"2001","journal-title":"Journal of Urology"},{"key":"10.1016\/j.phrs.2013.01.010_bib0045","first-page":"R534","article-title":"Overexpression of NGF in mouse urothelium leads to neuronal hyperinnervation, pelvic sensitivity, and changes in urinary bladder function","volume":"298","author":"Schnegelsberg","year":"2010","journal-title":"American Journal of Physiology: Regulatory Integrative and Comparative Physiology"},{"key":"10.1016\/j.phrs.2013.01.010_bib0050","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1002\/nau.21022","article-title":"Nerve growth factor in bladder dysfunction: contributing factor, biomarker, and therapeutic target","volume":"30","author":"Ochodnicky","year":"2011","journal-title":"Neurourology and Urodynamics"},{"key":"10.1016\/j.phrs.2013.01.010_bib0055","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1038\/nrurol.2012.178","article-title":"Neurotrophins as regulators of urinary bladder function","volume":"9","author":"Ochodnicky","year":"2012","journal-title":"Nature Reviews Urology"},{"key":"10.1016\/j.phrs.2013.01.010_bib0060","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1016\/S0022-5347(05)65931-9","article-title":"Histological and neurotrophic changes triggered by varying models of bladder inflammation","volume":"166","author":"Dupont","year":"2001","journal-title":"Journal of Urology"},{"key":"10.1016\/j.phrs.2013.01.010_bib0065","doi-asserted-by":"crossref","first-page":"2440","DOI":"10.1016\/j.juro.2010.02.003","article-title":"Increased urinary nerve growth factor as a predictor of persistent detrusor overactivity after bladder outlet obstruction relief in a rat model","volume":"183","author":"Lee","year":"2010","journal-title":"Journal of Urology"},{"key":"10.1016\/j.phrs.2013.01.010_bib0070","doi-asserted-by":"crossref","first-page":"2270","DOI":"10.1016\/j.juro.2008.01.146","article-title":"Urinary nerve growth factor level could be a potential biomarker for diagnosis of overactive bladder","volume":"179","author":"Liu","year":"2008","journal-title":"Journal of Urology"},{"key":"10.1016\/j.phrs.2013.01.010_bib0075","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1016\/j.eururo.2010.02.031","article-title":"Trigonal injection of botulinum toxin A in patients with refractory bladder pain syndrome\/interstitial cystitis","volume":"58","author":"Pinto","year":"2010","journal-title":"European Urology"},{"key":"10.1016\/j.phrs.2013.01.010_bib0080","doi-asserted-by":"crossref","first-page":"2944","DOI":"10.1016\/j.juro.2009.08.022","article-title":"Functional transient receptor potential vanilloid 1 is expressed in human urothelial cells","volume":"182","author":"Charrua","year":"2009","journal-title":"Journal of Urology"},{"key":"10.1016\/j.phrs.2013.01.010_bib0085","doi-asserted-by":"crossref","first-page":"13396","DOI":"10.1073\/pnas.231243698","article-title":"Vanilloid receptor expression suggests a sensory role for urinary bladder epithelial cells","volume":"98","author":"Birder","year":"2001","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"10.1016\/j.phrs.2013.01.010_bib0090","doi-asserted-by":"crossref","first-page":"21257","DOI":"10.1074\/jbc.M109.020206","article-title":"The TRPV4 cation channel mediates stretch-evoked Ca2+ influx and ATP release in primary urothelial cell cultures","volume":"284","author":"Mochizuki","year":"2009","journal-title":"Journal of Biological Chemistry"},{"key":"10.1016\/j.phrs.2013.01.010_bib0095","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1016\/j.phrs.2011.06.009","article-title":"Muscarinic receptors stimulate cell proliferation in the human urothelium-derived cell line UROtsa","volume":"64","author":"Arrighi","year":"2011","journal-title":"Pharmacological Research"},{"key":"10.1016\/j.phrs.2013.01.010_bib0100","doi-asserted-by":"crossref","first-page":"E293","DOI":"10.1111\/j.1464-410X.2012.011145.x","article-title":"Expression profiling of G-protein-coupled receptors in human urothelium and related cell lines","volume":"110","author":"Ochodnicky","year":"2012","journal-title":"BJU International"},{"key":"10.1016\/j.phrs.2013.01.010_bib0105","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1007\/BF00165395","article-title":"Evidence for the involvement of bradykinin in chemically-evoked cystitis in anaesthetized rats","volume":"347","author":"Maggi","year":"1993","journal-title":"Naunyn-Schmiedebergs Archives of Pharmacology"},{"key":"10.1016\/j.phrs.2013.01.010_bib0110","doi-asserted-by":"crossref","first-page":"1757","DOI":"10.1016\/S0022-5347(05)67102-9","article-title":"Up-regulation of bradykinin response in rat and human bladder smooth muscle","volume":"164","author":"Sjuve","year":"2000","journal-title":"Journal of Urology"},{"key":"10.1016\/j.phrs.2013.01.010_bib0115","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1046\/j.1464-410X.1997.00092.x","article-title":"Spontaneously released substance P and bradykinin from isolated guinea-pig bladder","volume":"79","author":"Saban","year":"1997","journal-title":"British Journal of Urology"},{"key":"10.1016\/j.phrs.2013.01.010_bib0120","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1038\/sj.bjp.0702769","article-title":"Pharmacological and molecular evidence for kinin B1 receptor expression in urinary bladder of cyclophosphamide-treated rats","volume":"128","author":"Belichard","year":"1999","journal-title":"British Journal of Pharmacology"},{"key":"10.1016\/j.phrs.2013.01.010_bib0125","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1038\/sj.bjp.0706976","article-title":"Characterization of kinin receptors in human cultured detrusor smooth muscle cells","volume":"150","author":"Bellucci","year":"2007","journal-title":"British Journal of Pharmacology"},{"key":"10.1016\/j.phrs.2013.01.010_bib0130","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1111\/j.1476-5381.1995.tb17196.x","article-title":"Pharmacological analysis of the local and reflex responses to bradykinin on rat urinary bladder motility in vivo","volume":"114","author":"Lecci","year":"1995","journal-title":"British Journal of Pharmacology"},{"key":"10.1016\/j.phrs.2013.01.010_bib0135","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1113\/jphysiol.2004.071159","article-title":"Expression and function of bradykinin B1 and B2 receptors in normal and inflamed rat urinary bladder urothelium","volume":"562","author":"Chopra","year":"2005","journal-title":"Journal of Physiology"},{"key":"10.1016\/j.phrs.2013.01.010_bib0140","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1007\/BF00698738","article-title":"Immortalisation of human urothelial cells","volume":"23","author":"Petzoldt","year":"1995","journal-title":"Urological Research"},{"key":"10.1016\/j.phrs.2013.01.010_bib0145","doi-asserted-by":"crossref","first-page":"1014","DOI":"10.1016\/S0022-5347(17)35677-X","article-title":"Effect of bradykinin and tachykinin receptor antagonist on xylene-induced cystitis in rats","volume":"150","author":"Giuliani","year":"1993","journal-title":"Journal of Urology"},{"key":"10.1016\/j.phrs.2013.01.010_bib0150","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/S0014-2999(99)00833-X","article-title":"Prostaglandin-release impairment in the bladder epithelium of streptozotocin-induced diabetic rats","volume":"388","author":"Pinna","year":"2000","journal-title":"European Journal of Pharmacology"},{"key":"10.1016\/j.phrs.2013.01.010_bib0155","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1016\/j.ejphar.2010.09.050","article-title":"Biochemical and functional correlates of an increased membrane density of caveolae in hypertrophic rat urinary bladder","volume":"649","author":"Shakirova","year":"2010","journal-title":"European Journal of Pharmacology"},{"key":"10.1016\/j.phrs.2013.01.010_bib0160","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/S0022-3565(24)37773-0","article-title":"Inflammation modifies the role of cyclooxygenases in the contractile responses of the rat detrusor smooth muscle to kinin agonists","volume":"287","author":"Meini","year":"1998","journal-title":"Journal of Pharmacology and Experimental Therapeutics"},{"key":"10.1016\/j.phrs.2013.01.010_bib0165","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/j.peptides.2009.12.003","article-title":"Bradykinin increases the secretion and expression of endothelin-1 through kinin B2 receptors in melanoma cells","volume":"31","author":"Andoh","year":"2010","journal-title":"Peptides"},{"key":"10.1016\/j.phrs.2013.01.010_bib0170","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.ejphar.2004.10.004","article-title":"Pharmacological and functional characterization of bradykinin B2 receptor in human prostate","volume":"504","author":"Srinivasan","year":"2004","journal-title":"European Journal of Pharmacology"},{"key":"10.1016\/j.phrs.2013.01.010_bib0175","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/S0167-0115(99)00009-9","article-title":"Kinin B1 receptor-mediated motor responses in normal or inflamed rat urinary bladder in vivo","volume":"80","author":"Lecci","year":"1999","journal-title":"Regulatory Peptides"},{"key":"10.1016\/j.phrs.2013.01.010_bib0180","doi-asserted-by":"crossref","first-page":"E397","DOI":"10.1111\/j.1464-410X.2012.10966.x","article-title":"Inhibition of stretching-evoked ATP release from bladder mucosa by anticholinergic agents","volume":"110","author":"Young","year":"2012","journal-title":"BJU International"},{"key":"10.1016\/j.phrs.2013.01.010_bib0185","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1016\/j.ceca.2011.03.008","article-title":"Intracellular Ca(2+) regulation and electrophysiological properties of bladder urothelium subjected to stretch and exogenous agonists","volume":"49","author":"Wu","year":"2011","journal-title":"Cell Calcium"},{"key":"10.1016\/j.phrs.2013.01.010_bib0190","first-page":"F332","article-title":"Kinetics of urothelial ATP release","volume":"291","author":"Lewis","year":"2006","journal-title":"American Journal of Physiology: Renal Physiology"},{"key":"10.1016\/j.phrs.2013.01.010_bib0195","doi-asserted-by":"crossref","first-page":"2412","DOI":"10.1172\/JCI24086","article-title":"ATP and purinergic receptor-dependent membrane traffic in bladder umbrella cells","volume":"115","author":"Wang","year":"2005","journal-title":"Journal of Clinical Investigation"},{"key":"10.1016\/j.phrs.2013.01.010_bib0200","first-page":"F423","article-title":"Feline interstitial cystitis results in mechanical hypersensitivity and altered ATP release from bladder urothelium","volume":"285","author":"Birder","year":"2003","journal-title":"American Journal of Physiology: Renal Physiology"},{"key":"10.1016\/j.phrs.2013.01.010_bib0205","first-page":"F821","article-title":"Expression and function of rat urothelial P2Y receptors","volume":"294","author":"Chopra","year":"2008","journal-title":"American Journal of Physiology: Renal Physiology"},{"key":"10.1016\/j.phrs.2013.01.010_bib0210","first-page":"F971","article-title":"Heterogeneity of muscarinic receptor-mediated Ca2+ responses in cultured urothelial cells from rat","volume":"294","author":"Kullmann","year":"2008","journal-title":"American Journal of Physiology: Renal Physiology"},{"key":"10.1016\/j.phrs.2013.01.010_bib0215","doi-asserted-by":"crossref","first-page":"2434","DOI":"10.1097\/01.ju.0000143549.29867.4e","article-title":"Cyclophosphamide induced cystitis alters neurotrophin and receptor tyrosine kinase expression in pelvic ganglia and bladder","volume":"172","author":"Murray","year":"2004","journal-title":"Journal of Urology"},{"key":"10.1016\/j.phrs.2013.01.010_bib0220","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/1044-7431(91)90008-C","article-title":"Nerve growth factor gene expression: involvement of a downstream AP-1 element in basal and modulated transcription","volume":"2","author":"D\u2019Melo","year":"1991","journal-title":"Molecular and Cellular Neurosciences"},{"key":"10.1016\/j.phrs.2013.01.010_bib0225","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1046\/j.1523-1747.2003.12428.x","article-title":"Histamine enhances the production of nerve growth factor in human keratinocytes","volume":"121","author":"Kanda","year":"2003","journal-title":"Journal of Investigative Dermatology"},{"key":"10.1016\/j.phrs.2013.01.010_bib0230","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/0006-8993(94)01337-H","article-title":"Interactions between second messenger pathways influence NGF synthesis in mouse primary astrocytes","volume":"672","author":"Jehan","year":"1995","journal-title":"Brain Research"},{"key":"10.1016\/j.phrs.2013.01.010_bib0235","doi-asserted-by":"crossref","first-page":"C1018","DOI":"10.1152\/ajpcell.1995.269.4.C1018","article-title":"Protein kinase C in cyclic stretch-induced nerve growth factor production by urinary tract smooth muscle cells","volume":"269","author":"Persson","year":"1995","journal-title":"American Journal of Physiology"},{"key":"10.1016\/j.phrs.2013.01.010_bib0240","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1002\/(SICI)1097-4652(200006)183:3<289::AID-JCP1>3.0.CO;2-6","article-title":"Stretch-activated signaling of nerve growth factor secretion in bladder and vascular smooth muscle cells from hypertensive and hyperactive rats","volume":"183","author":"Clemow","year":"2000","journal-title":"Journal of Cellular Physiology"},{"key":"10.1016\/j.phrs.2013.01.010_bib0245","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1111\/j.1464-410X.2006.06207.x","article-title":"Effects of intravesical instillation of cyclooxygenase-2 inhibitor on the expression of inducible nitric oxide synthase and nerve growth factor in cyclophosphamide-induced overactive bladder","volume":"98","author":"Jang","year":"2006","journal-title":"BJU International"},{"key":"10.1016\/j.phrs.2013.01.010_bib0250","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1006\/exnr.1999.7254","article-title":"Changes in urinary bladder neurotrophic factor mRNA and NGF protein following urinary bladder dysfunction","volume":"161","author":"Vizzard","year":"2000","journal-title":"Experimental Neurology"},{"key":"10.1016\/j.phrs.2013.01.010_bib0255","doi-asserted-by":"crossref","first-page":"1737","DOI":"10.1111\/j.1476-5381.2012.02127.x","article-title":"Effects of kinin B(1) and B(2) receptor antagonists on overactive urinary bladder syndrome induced by spinal cord injury in rats","volume":"167","author":"Forner","year":"2012","journal-title":"British Journal of Pharmacology"},{"key":"10.1016\/j.phrs.2013.01.010_bib0260","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.autneu.2011.09.005","article-title":"Rat detrusor overactivity induced by chronic spinalization can be abolished by a transient receptor potential vanilloid 1 (TRPV1) antagonist","volume":"166","author":"Santos-Silva","year":"2012","journal-title":"Autonomic Neuroscience"},{"key":"10.1016\/j.phrs.2013.01.010_bib0265","doi-asserted-by":"crossref","first-page":"1537","DOI":"10.1016\/j.juro.2006.11.046","article-title":"Transient receptor potential vanilloid subfamily 1 is essential for the generation of noxious bladder input and bladder overactivity in cystitis","volume":"177","author":"Charrua","year":"2007","journal-title":"Journal of Urology"},{"key":"10.1016\/j.phrs.2013.01.010_bib0270","first-page":"F49","article-title":"Expression and distribution of transient receptor potential (TRP) channels in bladder epithelium","volume":"300","author":"Yu","year":"2011","journal-title":"American Journal of Physiology: Renal Physiology"},{"key":"10.1016\/j.phrs.2013.01.010_bib0275","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1038\/nn902","article-title":"Altered urinary bladder function in mice lacking the vanilloid receptor TRPV1","volume":"5","author":"Birder","year":"2002","journal-title":"Nature Neuroscience"},{"key":"10.1016\/j.phrs.2013.01.010_bib0280","first-page":"F692","article-title":"Functional characterization of transient receptor potential channels in mouse urothelial cells","volume":"298","author":"Everaerts","year":"2010","journal-title":"American Journal of Physiology: Renal Physiology"},{"key":"10.1016\/j.phrs.2013.01.010_bib0285","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.ejphar.2004.07.076","article-title":"Sensitization of vanilloid receptor 1 induced by bradykinin via the activation of second messenger signaling cascades in rat primary afferent neurons","volume":"498","author":"Tang","year":"2004","journal-title":"European Journal of Pharmacology"},{"key":"10.1016\/j.phrs.2013.01.010_bib0290","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1038\/35082088","article-title":"Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns(4,5)P2-mediated inhibition","volume":"411","author":"Chuang","year":"2001","journal-title":"Nature"}],"container-title":["Pharmacological Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1043661813000200?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1043661813000200?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,7]],"date-time":"2026-03-07T10:44:16Z","timestamp":1772880256000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1043661813000200"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,4]]},"references-count":58,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,4]]}},"alternative-id":["S1043661813000200"],"URL":"https:\/\/doi.org\/10.1016\/j.phrs.2013.01.010","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.717977219.793470755","asserted-by":"object"}]},"ISSN":["1043-6618"],"issn-type":[{"value":"1043-6618","type":"print"}],"subject":[],"published":{"date-parts":[[2013,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Bradykinin modulates spontaneous nerve growth factor production and stretch-induced ATP release in human urothelium","name":"articletitle","label":"Article Title"},{"value":"Pharmacological Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.phrs.2013.01.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}