{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T14:30:06Z","timestamp":1791297006277,"version":"4.1.0"},"reference-count":57,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2014,9,1]],"date-time":"2014-09-01T00:00:00Z","timestamp":1409529600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Pharmacological Research"],"published-print":{"date-parts":[[2014,9]]},"DOI":"10.1016\/j.phrs.2014.05.008","type":"journal-article","created":{"date-parts":[[2014,5,24]],"date-time":"2014-05-24T08:48:37Z","timestamp":1400921317000},"page":"144-150","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":68,"special_numbering":"C","title":["Classical and pleiotropic actions of dipyridamole: Not enough light to illuminate the dark tunnel?"],"prefix":"10.1016","volume":"87","author":[{"given":"Pitchai","family":"Balakumar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying Hui","family":"Nyo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raja","family":"Renushia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Devarajan","family":"Raaginey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ann Nah","family":"Oh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajavel","family":"Varatharajan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sokkalingam A.","family":"Dhanaraj","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.phrs.2014.05.008_bib0005","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.vph.2007.12.004","article-title":"Dipyridamole, cerebrovascular disease, and the vasculature","volume":"48","author":"Chakrabarti","year":"2008","journal-title":"Vascul Pharmacol"},{"key":"10.1016\/j.phrs.2014.05.008_bib0010","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1111\/j.1749-6632.2010.05732.x","article-title":"Effect of intravenous administration of dipyridamole in a rat model of chronic cerebral ischemia","volume":"1207","author":"Melani","year":"2010","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.phrs.2014.05.008_bib0015","doi-asserted-by":"crossref","first-page":"1588","DOI":"10.1253\/circj.CJ-08-0242","article-title":"Dipyridamole therapy improves long-term survival after complete revascularization in patients with impaired cardiac function: a propensity analysis","volume":"72","author":"Ikeda","year":"2008","journal-title":"Circ J"},{"key":"10.1016\/j.phrs.2014.05.008_bib0020","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1016\/j.freeradbiomed.2010.10.714","article-title":"Dipyridamole reverses peripheral ischemia and induces angiogenesis in the Db\/Db diabetic mouse hind-limb model by decreasing oxidative stress","volume":"50","author":"Pattillo","year":"2011","journal-title":"Free Radic Biol Med"},{"key":"10.1016\/j.phrs.2014.05.008_bib0025","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1093\/cvr\/cvq002","article-title":"Dipyridamole enhances ischaemia-induced arteriogenesis through an endocrine nitrite\/nitric oxide-dependent pathway","volume":"85","author":"Venkatesh","year":"2010","journal-title":"Cardiovasc Res"},{"key":"10.1016\/j.phrs.2014.05.008_bib0030","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1007\/s12975-010-0062-0","article-title":"Dipyridamole treatment prior to stroke onset: examining post-stroke cerebral circulation and outcome in rabbits","volume":"2","author":"d\u2019Esterre","year":"2011","journal-title":"Transl Stroke Res"},{"key":"10.1016\/j.phrs.2014.05.008_bib0035","doi-asserted-by":"crossref","first-page":"s39","DOI":"10.1161\/ATVBAHA.107.160226","article-title":"Translational therapeutics of dipyridamole","volume":"28","author":"Kim","year":"2008","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.phrs.2014.05.008_bib0040","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1007\/s13311-011-0060-2","article-title":"Antiplatelet agents for stroke prevention","volume":"8","author":"Yip","year":"2011","journal-title":"Neurotherapeutics"},{"key":"10.1016\/j.phrs.2014.05.008_bib0045","doi-asserted-by":"crossref","first-page":"1358","DOI":"10.1161\/STROKEAHA.107.496281","article-title":"Aspirin plus dipyridamole versus aspirin for prevention of vascular events after stroke or TIA: a meta-analysis","volume":"39","author":"Verro","year":"2008","journal-title":"Stroke"},{"key":"10.1016\/j.phrs.2014.05.008_bib0050","doi-asserted-by":"crossref","first-page":"1218","DOI":"10.1136\/jnnp.2008.143875","article-title":"Dipyridamole plus aspirin versus aspirin alone in secondary prevention after TIA or stroke: a meta-analysis by risk","volume":"79","author":"Halkes","year":"2008","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.phrs.2014.05.008_bib0055","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3310\/hta15310","article-title":"Clopidogrel and modified-release dipyridamole for the prevention of occlusive vascular events (review of Technology Appraisal No. 90): a systematic review and economic analysis","volume":"15","author":"Greenhalgh","year":"2011","journal-title":"Health Technol Assess"},{"issue":"3","key":"10.1016\/j.phrs.2014.05.008_bib0060","first-page":"CD001820","article-title":"Dipyridamole for preventing stroke and other vascular events in patients with vascular disease","author":"De Schryver","year":"2007","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.phrs.2014.05.008_bib0065","doi-asserted-by":"crossref","first-page":"2684","DOI":"10.1161\/STROKEAHA.110.586453","article-title":"Prevention with low-dose aspirin plus dipyridamole in patients with disabling stroke","volume":"41","author":"Dippel","year":"2010","journal-title":"Stroke"},{"key":"10.1016\/j.phrs.2014.05.008_bib0070","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1097\/MJT.0b013e31814b17bf","article-title":"Targeting the inflammatory response in secondary stroke prevention: a role for combining aspirin and extended-release dipyridamole","volume":"16","author":"Weyrich","year":"2009","journal-title":"Am J Ther"},{"key":"10.1016\/j.phrs.2014.05.008_bib0075","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1136\/ebm.14.2.46","article-title":"Aspirin plus extended-release dipyridamole and clopidogrel were similarly effective for preventing recurrent stroke","volume":"14","author":"Sloan","year":"2009","journal-title":"Evid Based Med"},{"key":"10.1016\/j.phrs.2014.05.008_bib0080","doi-asserted-by":"crossref","first-page":"728","DOI":"10.2146\/ajhp080645","article-title":"Safety of fixed-dose aspirin-extended-release dipyridamole in patients with ischemic heart disease","volume":"67","author":"Crown","year":"2010","journal-title":"Am J Health Syst Pharm"},{"key":"10.1016\/j.phrs.2014.05.008_bib0085","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1186\/1471-2377-12-67","article-title":"Comparative evaluation of treatment with low-dose aspirin plus dipyridamole versus aspirin only in patients with acute ischaemic stroke","volume":"12","author":"Arnarsdottir","year":"2012","journal-title":"BMC Neurol"},{"key":"10.1016\/j.phrs.2014.05.008_bib0090","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.jns.2013.06.025","article-title":"The efficacy and safety of aspirin plus dipyridamole versus aspirin in secondary prevention following TIA or stroke: a meta-analysis of randomized controlled trials","volume":"332","author":"Li","year":"2013","journal-title":"J Neurol Sci"},{"key":"10.1016\/j.phrs.2014.05.008_bib0095","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1159\/000351915","article-title":"Antithrombotic therapy in transient ischemic attack patients","volume":"33","author":"Held","year":"2014","journal-title":"Front Neurol Neurosci"},{"key":"10.1016\/j.phrs.2014.05.008_bib0100","doi-asserted-by":"crossref","first-page":"1706","DOI":"10.1056\/NEJMoa060989","article-title":"Clopidogrel and aspirin versus aspirin alone for the prevention of atherothrombotic events","volume":"354","author":"Bhatt","year":"2006","journal-title":"N Engl J Med"},{"key":"10.1016\/j.phrs.2014.05.008_bib0105","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/S0140-6736(04)16721-4","article-title":"Aspirin and clopidogrel compared with clopidogrel alone after recent ischaemic stroke or transient ischaemic attack in high-risk patients (MATCH): randomised, double-blind, placebo-controlled trial","volume":"364","author":"Diener","year":"2004","journal-title":"Lancet"},{"key":"10.1016\/j.phrs.2014.05.008_bib0110","doi-asserted-by":"crossref","first-page":"1665","DOI":"10.1016\/S0140-6736(06)68734-5","article-title":"Aspirin plus dipyridamole versus aspirin alone after cerebral ischemia of arterial origin (ESPRIT): randomised controlled trial","volume":"367","author":"Halkes","year":"2006","journal-title":"Lancet"},{"key":"10.1016\/j.phrs.2014.05.008_bib0115","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1161\/01.CIR.0000154607.90506.45","article-title":"Dipyridamole selectively inhibits inflammatory gene expression in platelet-monocyte aggregates","volume":"111","author":"Weyrich","year":"2005","journal-title":"Circulation"},{"key":"10.1016\/j.phrs.2014.05.008_bib0120","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1160\/TH12-05-0326","article-title":"Dipyridamole decreases inflammatory metalloproteinase-9 expression and release by human monocytes","volume":"109","author":"Massaro","year":"2013","journal-title":"Thromb Haemost"},{"key":"10.1016\/j.phrs.2014.05.008_bib0125","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1159\/000319072","article-title":"Amelioration of inflammation and cytotoxicity by dipyridamole in brain endothelial cells","volume":"30","author":"Guo","year":"2010","journal-title":"Cerebrovasc Dis"},{"key":"10.1016\/j.phrs.2014.05.008_bib0130","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.ejphar.2011.12.038","article-title":"Treatment with dipyridamole improves cardiac function and prevent injury in a rat model of hemorrhage","volume":"678","author":"Soliman","year":"2012","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.phrs.2014.05.008_bib0135","doi-asserted-by":"crossref","first-page":"R289","DOI":"10.1186\/cc10576","article-title":"Dipyridamole augments the antiinflammatory response during human endotoxemia","volume":"15","author":"Ramakers","year":"2011","journal-title":"Crit Care"},{"key":"10.1016\/j.phrs.2014.05.008_bib0140","doi-asserted-by":"crossref","first-page":"1406","DOI":"10.1016\/j.intimp.2010.08.006","article-title":"Influence of dipyridamole and its combination with NO donor or NO synthase inhibitor on adjuvant arthritis","volume":"10","author":"Gomaa","year":"2010","journal-title":"Int Immunopharmacol"},{"key":"10.1016\/j.phrs.2014.05.008_bib0145","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1186\/1742-2094-10-89","article-title":"Reduction of microglial activity in a model of multiple sclerosis by dipyridamole","volume":"10","author":"Sloka","year":"2013","journal-title":"J. Neuroinflammation"},{"key":"10.1016\/j.phrs.2014.05.008_bib0150","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1097\/FJC.0b013e31813542db","article-title":"Redox state of dipyridamole is a critical determinant for its beneficial antioxidant and antiinflammatory effects","volume":"50","author":"Chakrabarti","year":"2007","journal-title":"J Cardiovasc Pharmacol"},{"key":"10.1016\/j.phrs.2014.05.008_bib0155","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1159\/000338053","article-title":"Dipyridamole in antithrombotic treatment","volume":"47","author":"Eisert","year":"2012","journal-title":"Adv Cardiol"},{"key":"10.1016\/j.phrs.2014.05.008_bib0160","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1002\/ccd.22724","article-title":"Dipyridamole versus verapamil for treatment of no-reflow during primary angioplasty","volume":"76","author":"Tanzilli","year":"2010","journal-title":"Catheter Cardiovasc Interv"},{"key":"10.1016\/j.phrs.2014.05.008_bib0165","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1679\/aohc.71.235","article-title":"Dipyridamole inhibits intracellular calcium transients in isolated rat arteriole smooth muscle cells","volume":"71","author":"Saino","year":"2008","journal-title":"Arch Histol Cytol"},{"key":"10.1016\/j.phrs.2014.05.008_bib0170","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1111\/j.1742-7843.2006.pto_516.x","article-title":"Mechanism of dipyridamole's action in inhibition of venous and arterial smooth muscle cell proliferation","volume":"99","author":"Zhuplatov","year":"2006","journal-title":"Basic Clin Pharmacol Toxicol"},{"key":"10.1016\/j.phrs.2014.05.008_bib0175","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.ejphar.2009.03.063","article-title":"Dipyridamole inhibits cobalt chloride-induced osteopontin expression in NRK52E cells","volume":"613","author":"Chen","year":"2009","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.phrs.2014.05.008_bib0180","doi-asserted-by":"crossref","first-page":"1242","DOI":"10.1253\/circj.CJ-09-0561","article-title":"Dipyridamole suppresses high glucose-induced osteopontin secretion and mRNA expression in rat aortic smooth muscle cells","volume":"74","author":"Hsieh","year":"2010","journal-title":"Circ J"},{"key":"10.1016\/j.phrs.2014.05.008_bib0185","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.cellsig.2011.09.007","article-title":"Healing the diabetic heart: does myocardial preconditioning work","volume":"24","author":"Balakumar","year":"2012","journal-title":"Cell Signal"},{"key":"10.1016\/j.phrs.2014.05.008_bib0190","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1016\/j.cellsig.2011.11.003","article-title":"Preconditioning the hyperlipidemic myocardium: fact or fantasy","volume":"24","author":"Balakumar","year":"2012","journal-title":"Cell Signal"},{"key":"10.1016\/j.phrs.2014.05.008_bib0195","doi-asserted-by":"crossref","first-page":"1148","DOI":"10.1016\/S0022-3565(25)12166-6","article-title":"Ischemic preconditioning, adenosine and bethanechol protect spontaneously hypertensive isolated rat hearts","volume":"275","author":"Boutros","year":"1995","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1016\/j.phrs.2014.05.008_bib0200","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1016\/0003-4975(95)00332-F","article-title":"Protective effects of adenosine in the reversibly injured heart","volume":"60","author":"Lasley","year":"1995","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.phrs.2014.05.008_bib0205","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/S1010-7940(00)00605-9","article-title":"Pretreatment of human myocardium with adenosine","volume":"19","author":"Wasir","year":"2001","journal-title":"Eur J Cardiothorac Surg"},{"key":"10.1016\/j.phrs.2014.05.008_bib0210","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/j.yjmcc.2005.06.001","article-title":"Adenosine triggers preconditioning through MEK\/ERK1\/2 signalling pathway during hypoxia\/reoxygenation in neonatal rat cardiomyocytes","volume":"39","author":"Germack","year":"2005","journal-title":"J Mol Cell Cardiol"},{"key":"10.1016\/j.phrs.2014.05.008_bib0215","first-page":"2313","article-title":"Adenosine preconditioning reduces myocardial injury in patients undergoing off-pump coronary artery bypass grafting surgery","volume":"87","author":"Yang","year":"2007","journal-title":"Zhonghua Yi Xue Za Zhi"},{"key":"10.1016\/j.phrs.2014.05.008_bib0220","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1007\/s12012-012-9182-y","article-title":"Adenosine transport blockade restores attenuated cardioprotective effects of adenosine preconditioning in the isolated diabetic rat heart: potential crosstalk with opioid receptors","volume":"13","author":"Sharma","year":"2013","journal-title":"Cardiovasc Toxicol"},{"key":"10.1016\/j.phrs.2014.05.008_bib0225","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1007\/s10557-010-6252-x","article-title":"Dipyridamole with low-dose aspirin augments the infarct size-limiting effects of simvastatin","volume":"24","author":"Ye","year":"2010","journal-title":"Cardiovasc Drugs Ther"},{"key":"10.1016\/j.phrs.2014.05.008_bib0230","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1152\/ajpheart.00210.2007","article-title":"Enhanced cardioprotection against ischemia\u2013reperfusion injury with a dipyridamole and low-dose atorvastatin combination","volume":"293","author":"Ye","year":"2007","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"10.1016\/j.phrs.2014.05.008_bib0235","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.jsha.2011.01.004","article-title":"Nucleoside transport inhibitor, dipyridamole, induced myocardial protection following hemorrhagic shock in ex vivo perfused rat hearts","volume":"23","author":"Soliman","year":"2011","journal-title":"J Saudi Heart Assoc"},{"key":"10.1016\/j.phrs.2014.05.008_bib0240","first-page":"140","article-title":"Administration of aspirin\u2013dipyridamole reduces proteinuria in diabetic nephropathy","volume":"4","author":"Hopper","year":"1989","journal-title":"Nephrol Dial Transplant"},{"key":"10.1016\/j.phrs.2014.05.008_bib0245","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1080\/003655902753679454","article-title":"A comparative randomized and placebo-controlled short-term trial of aspirin and dipyridamole for overt type-2 diabetic nephropathy","volume":"36","author":"Khajehdehi","year":"2002","journal-title":"Scand J Urol Nephrol"},{"key":"10.1016\/j.phrs.2014.05.008_bib0250","first-page":"130","article-title":"Dipyridamole reduces urinary albumin excretion in diabetic patients with normo- or microalbuminuria","volume":"33","author":"Aizawa","year":"1990","journal-title":"Clin Nephrol"},{"key":"10.1016\/j.phrs.2014.05.008_bib0255","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1016\/j.ijcard.2014.01.053","article-title":"Low-dose dipyridamole treatment partially prevents diabetes mellitus-induced vascular endothelial and renal abnormalities in rats","volume":"172","author":"Sharma","year":"2014","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.phrs.2014.05.008_bib0260","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1136\/jnnp.2008.147918","article-title":"Risk indicators for development of headache during dipyridamole treatment after cerebral ischaemia of arterial origin","volume":"80","author":"Halkes","year":"2009","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.phrs.2014.05.008_bib0265","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1159\/000222782","article-title":"Dipyridamole-associated headache in stroke patients\u2014interindividual differences","volume":"62","author":"L\u00f6kk","year":"2009","journal-title":"Eur Neurol"},{"key":"10.1016\/j.phrs.2014.05.008_bib0270","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1161\/01.CIR.57.6.1103","article-title":"Conditions for vasodilator-induced coronary steal in experimental myocardial ischemia","volume":"57","author":"Becker","year":"1978","journal-title":"Circulation"},{"key":"10.1016\/j.phrs.2014.05.008_bib0275","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1536\/ihj.23.79","article-title":"Conditions for coronary steal caused by coronary vasodilator in man","volume":"23","author":"Ando","year":"1982","journal-title":"Jpn Heart J"},{"key":"10.1016\/j.phrs.2014.05.008_bib0280","doi-asserted-by":"crossref","first-page":"759103","DOI":"10.1155\/2013\/759103","article-title":"Pivotal roles of monocytes\/macrophages in stroke","volume":"2013","author":"Chiba","year":"2013","journal-title":"Mediators Inflamm"},{"key":"10.1016\/j.phrs.2014.05.008_bib0285","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1053\/euhj.2000.2172","article-title":"The coronary no-reflow phenomenon: a review of mechanisms and therapies","volume":"22","author":"Eeckhout","year":"2001","journal-title":"Eur Heart J"}],"container-title":["Pharmacological Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1043661814000747?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1043661814000747?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,5,3]],"date-time":"2025-05-03T02:46:10Z","timestamp":1746240370000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1043661814000747"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,9]]},"references-count":57,"alternative-id":["S1043661814000747"],"URL":"https:\/\/doi.org\/10.1016\/j.phrs.2014.05.008","relation":{},"ISSN":["1043-6618"],"issn-type":[{"value":"1043-6618","type":"print"}],"subject":[],"published":{"date-parts":[[2014,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Classical and pleiotropic actions of dipyridamole: Not enough light to illuminate the dark tunnel?","name":"articletitle","label":"Article Title"},{"value":"Pharmacological Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.phrs.2014.05.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}