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Neuroimmunol."},{"key":"10.1016\/j.phrs.2016.01.027_bib0910","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1093\/ajcn\/63.1.116","article-title":"The effect on human tumor necrosis factor alpha and interleukin 1 beta production of diets enriched in n-3 fatty acids from vegetable oil or fish oil","volume":"63","author":"Caughey","year":"1996","journal-title":"Am. J. Clin. 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Res."},{"key":"10.1016\/j.phrs.2016.01.027_bib0940","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.thromres.2012.11.028","article-title":"Platelet-leukocyte crosstalk: linking proinflammatory responses to procoagulant state","volume":"131","author":"Ghasemzadeh","year":"2013","journal-title":"Thromb. 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Haemost."},{"key":"10.1016\/j.phrs.2016.01.027_bib0975","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1038\/cgt.2015.21","article-title":"The receptor for advanced glycation end products (rage) enhances autophagy and neutrophil extracellular traps in pancreatic cancer","volume":"22","author":"Boone","year":"2015","journal-title":"Cancer Gene Ther."},{"key":"10.1016\/j.phrs.2016.01.027_bib0980","doi-asserted-by":"crossref","first-page":"2571","DOI":"10.1002\/eji.1830271016","article-title":"Chemoattractant receptor cross talk as a regulatory mechanism in leukocyte adhesion and migration","volume":"27","author":"Campbell","year":"1997","journal-title":"Eur. J. 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