{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,19]],"date-time":"2026-07-19T09:45:11Z","timestamp":1784454311132,"version":"3.55.0"},"reference-count":63,"publisher":"Elsevier BV","issue":"8-9","license":[{"start":{"date-parts":[[2011,6,1]],"date-time":"2011-06-01T00:00:00Z","timestamp":1306886400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Phytomedicine"],"published-print":{"date-parts":[[2011,6]]},"DOI":"10.1016\/j.phymed.2010.11.014","type":"journal-article","created":{"date-parts":[[2011,1,27]],"date-time":"2011-01-27T04:35:24Z","timestamp":1296102924000},"page":"731-738","source":"Crossref","is-referenced-by-count":83,"title":["The antidepressant effects and mechanism of action of total saponins from the caudexes and leaves of Panax notoginseng in animal models of depression"],"prefix":"10.1016","volume":"18","author":[{"given":"Hui","family":"Xiang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingxue","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baibing","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junhao","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bing","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhangxin","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feijun","family":"Xiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hualin","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.phymed.2010.11.014_bib0005","doi-asserted-by":"crossref","first-page":"2476","DOI":"10.1152\/jn.00797.2007","article-title":"BDNF induces calcium elevations associated with IBDNF, a nonselective cationic current mediated by TRPC channels","volume":"98","author":"Amaral","year":"2007","journal-title":"J. Neurophysiol."},{"key":"10.1016\/j.phymed.2010.11.014_bib0010","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1016\/j.pbb.2008.02.014","article-title":"Role for serotonin in the antidepressant-like effect of a flavonoid extract of Xiaobuxin-Tang","volume":"89","author":"An","year":"2008","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.phymed.2010.11.014_bib0015","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1016\/j.physbeh.2005.10.019","article-title":"Behavioral and physiological effects of chronic mild stress in female rats","volume":"87","author":"Baker","year":"2006","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.phymed.2010.11.014_bib0020","first-page":"212","article-title":"Action of caffeine on the spontaneous motility of the mouse","volume":"158","author":"Boissier","year":"1965","journal-title":"Arch. Int. Pharmacodyn. Ther."},{"key":"10.1016\/j.phymed.2010.11.014_bib0025","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1111\/j.1745-7254.2005.00034.x","article-title":"Anti-amnestic and anti-aging effects of ginsenoside Rg1 and Rb1 and its mechanism of action","volume":"26","author":"Cheng","year":"2005","journal-title":"Acta Pharmacol. Sin."},{"key":"10.1016\/j.phymed.2010.11.014_bib0030","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1016\/S0378-8741(00)00277-4","article-title":"Orally administered Panax notoginseng influence on rat spontaneous behaviour","volume":"73","author":"Cicero","year":"2000","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.phymed.2010.11.014_bib0035","first-page":"15","article-title":"The relevance of dopamine agonists in the treatment of depression","volume":"23","author":"Clausius","year":"2009","journal-title":"Neuropsychiatrie"},{"key":"10.1016\/j.phymed.2010.11.014_bib0040","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1111\/j.1476-5381.1963.tb01302.x","article-title":"A method for assessing the effects of drugs on the central actions of 5-hydroxytryptamine","volume":"20","author":"Corne","year":"1963","journal-title":"Br. J. Pharmacol. Chemother."},{"key":"10.1016\/j.phymed.2010.11.014_bib0045","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/S0031-9384(97)00042-5","article-title":"Diurnal variation in the effect of chronic mild stress on sucrose intake and preference","volume":"62","author":"D\u2019Aquila","year":"1997","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.phymed.2010.11.014_bib0050","doi-asserted-by":"crossref","first-page":"1417","DOI":"10.1016\/j.pnpbp.2009.07.020","article-title":"Antidepressant effects of ginseng total saponins in the forced swimming test and chronic mild stress models of depression","volume":"33","author":"Dang","year":"2009","journal-title":"Prog. Neuropsychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.phymed.2010.11.014_bib0055","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1037\/1064-1297.5.2.107","article-title":"Acute and chronic antidepressant drug treatment in the rat forced swimming test model of depression","volume":"5","author":"Detke","year":"1997","journal-title":"Exp. Clin. Psychopharmacol."},{"key":"10.1016\/j.phymed.2010.11.014_bib0060","doi-asserted-by":"crossref","first-page":"1300","DOI":"10.1016\/j.mehy.2006.09.040","article-title":"Is hippocampal atrophy a future drug target?","volume":"68","author":"Dhikav","year":"2007","journal-title":"Med. Hypotheses"},{"key":"10.1016\/j.phymed.2010.11.014_bib0065","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1002\/ptr.2024","article-title":"Chronic oral administration of ginseng extract results in behavioral change but has no effects in mice models of affective and anxiety disorders","volume":"21","author":"Einat","year":"2007","journal-title":"Phytother. Res."},{"key":"10.1016\/j.phymed.2010.11.014_bib0070","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.cpem.2007.11.003","article-title":"An update on antidepressant toxicity: an evolution of unique toxicities to master","volume":"9","author":"Erica","year":"2008","journal-title":"Clin. Pediatr. Emerg. Med."},{"key":"10.1016\/j.phymed.2010.11.014_bib0075","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/j.neuropharm.2005.09.005","article-title":"Blockade of intracellular calcium release induces an antidepressant-like effect in the mouse forced swimming test","volume":"50","author":"Galeotti","year":"2006","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.phymed.2010.11.014_bib0080","first-page":"173","article-title":"Observation of self-control about Seven Leaves Spirit Calmness Tablet toward anxiety neurosis","volume":"12","author":"Gong","year":"1998","journal-title":"Med. J. Commun."},{"key":"10.1016\/j.phymed.2010.11.014_bib0085","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1016\/j.pbb.2006.11.021","article-title":"Chronic mild stress inhibits BDNF protein expression and CREB activation in the dentate gyrus but not in the hippocampus proper","volume":"85","author":"Gr\u00f8nli","year":"2006","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.phymed.2010.11.014_bib0090","first-page":"132","article-title":"Effect of Chinese traditional medicine Sanchi on neuronal plasticity after focal cerebral ischemia reperfusion injury","volume":"18","author":"Guo","year":"2003","journal-title":"Chin. J. Rehabil."},{"issue":"Suppl 5","key":"10.1016\/j.phymed.2010.11.014_bib0095","doi-asserted-by":"crossref","first-page":"S625","DOI":"10.1016\/S0924-977X(06)70008-6","article-title":"Pharmacological profile of antidepressants: a likely basis for their efficacy and side effects?","volume":"16","author":"Hamon","year":"2006","journal-title":"Eur. Neuropsychopharmacol."},{"key":"10.1016\/j.phymed.2010.11.014_bib0100","first-page":"227","article-title":"Effect of Panax notoginseng Saponin on Ca2+, CaM in craniocerebral injury","volume":"19","author":"Han","year":"1999","journal-title":"Chin. J. Integr. Trad. West Med."},{"key":"10.1016\/j.phymed.2010.11.014_bib0105","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.expneurol.2006.03.013","article-title":"Immunohistochemical study of the serotonergic neuronal system in an animal model of the mood disorder","volume":"201","author":"Iritani","year":"2006","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.phymed.2010.11.014_bib0110","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1055\/s-2006-962058","article-title":"Effect of Panax ginseng root on the vertical and horizontal motor activities and on brain monoamine-related substances in mice","volume":"55","author":"Itoh","year":"1989","journal-title":"Planta Med."},{"key":"10.1016\/j.phymed.2010.11.014_bib0115","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1038\/sj.mp.4001920","article-title":"Serotonergic vulnerability and depression: assumptions, experimental evidence and implications","volume":"12","author":"Jans","year":"2007","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.phymed.2010.11.014_bib0120","doi-asserted-by":"crossref","first-page":"2395","DOI":"10.1038\/sj.npp.1301041","article-title":"Hippocampal cytogenesis correlates to escitalopram-mediated recovery in a chronic mild stress rat model of depression","volume":"31","author":"Jayatissa","year":"2006","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.phymed.2010.11.014_bib0125","first-page":"444","article-title":"The effect of ginsenoside Rb3 on the persistent sodium current in ischemic and normal neurons","volume":"15","author":"Jiang","year":"2007","journal-title":"Pharm. Clin. Res."},{"key":"10.1016\/j.phymed.2010.11.014_bib0130","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1034\/j.1399-5618.2002.40101.x","article-title":"Regulation of adult hippocampal neurogenesis: implications for novel theories of major depression","volume":"4","author":"Kempermann","year":"2001","journal-title":"Bipolar Disord."},{"key":"10.1016\/j.phymed.2010.11.014_bib0135","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1001\/archpsyc.62.6.617","article-title":"Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication","volume":"62","author":"Kessler","year":"2005","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.phymed.2010.11.014_bib0140","doi-asserted-by":"crossref","first-page":"6758","DOI":"10.1074\/jbc.275.10.6758","article-title":"Store-operated calcium entry in vascular endothelial cells is inhibited by cGMP via a protein kinase G-dependent mechanism","volume":"275","author":"Kwan","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.phymed.2010.11.014_bib0145","first-page":"354","article-title":"The chemical component of the leaves of Panax notoginseng","volume":"18","author":"Li","year":"2000","journal-title":"J. Pharm. Pract."},{"key":"10.1016\/j.phymed.2010.11.014_bib0150","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1093\/chromsci\/43.8.421","article-title":"Determination of four active saponins of Panax notoginseng in rat feces by high-performance liquid chromatography","volume":"43","author":"Li","year":"2005","journal-title":"J. Chromatogr. Sci."},{"key":"10.1016\/j.phymed.2010.11.014_bib0155","doi-asserted-by":"crossref","first-page":"2485","DOI":"10.1081\/JLC-120014269","article-title":"HPLC determination of ginsenosides content in ginseng dietary supplements using ultraviolet detection","volume":"25","author":"Li","year":"2002","journal-title":"J. Liq. Chromatogr. Relat. Technol."},{"key":"10.1016\/j.phymed.2010.11.014_bib0160","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1016\/j.eplepsyres.2006.05.010","article-title":"Anticonvulsant and neuroprotective effects of ginsenosides in rats","volume":"70","author":"Lian","year":"2006","journal-title":"Epilepsy Res."},{"key":"10.1016\/j.phymed.2010.11.014_bib0165","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.pbb.2007.09.019","article-title":"Stress and the brain: solving the puzzle using microdialysis","volume":"90","author":"Linthorst","year":"2008","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.phymed.2010.11.014_bib0170","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/j.seppur.2006.09.004","article-title":"Purification and quantification of ginsenoside Rb3 and Rc from crude extracts of caudexes and leaves of Panax notoginseng","volume":"54","author":"Liu","year":"2007","journal-title":"Sep. Purif. Technol."},{"key":"10.1016\/j.phymed.2010.11.014_bib0175","first-page":"213","article-title":"Effect of saponins of Panax notoginseng on synaptosomal 45Ca uptake","volume":"18","author":"Ma","year":"1997","journal-title":"Acta Pharmacol. Sin."},{"key":"10.1016\/j.phymed.2010.11.014_bib0180","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1016\/0014-2999(68)90126-X","article-title":"Aggressive behaviour induced by large doses of 2-(2,6-dichlorophenylamino)-2-imidazoline hydrochloride (ST 155) in mice","volume":"3","author":"Morpurgo","year":"1968","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.phymed.2010.11.014_bib0185","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1211\/jpp.58.8.0001","article-title":"Pharmacological activity of sanchi ginseng (Panax notoginseng)","volume":"58","author":"Ng","year":"2006","journal-title":"J. Pharm. Pharmacol."},{"key":"10.1016\/j.phymed.2010.11.014_bib0190","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1038\/266730a0","article-title":"Depression: a new animal model sensitive to antidepressant treatments","volume":"266","author":"Porsolt","year":"1977","journal-title":"Nature"},{"key":"10.1016\/j.phymed.2010.11.014_bib0195","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1016\/0028-3908(95)00102-C","article-title":"The effect of 5-HT1A receptor ligands in a mild stress model of depression","volume":"34","author":"Przegali\u0144ski","year":"1995","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.phymed.2010.11.014_bib0200","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.brainres.2004.06.030","article-title":"Ginsenosides Rb1 and Rg1 effects on mesencephalic dopaminergic cells stressed with glutamate","volume":"1021","author":"Radad","year":"2004","journal-title":"Brain Res."},{"key":"10.1016\/j.phymed.2010.11.014_bib0205","first-page":"86","article-title":"Comparative study on the antidepressant-like effect of Chaihu-jia-Longgu-Muli-Decoction (CLMD) and its relative decoctions","volume":"16","author":"Ren","year":"2008","journal-title":"Pharm. Clin. Res."},{"key":"10.1016\/j.phymed.2010.11.014_bib0210","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1016\/j.pbb.2007.01.006","article-title":"Depression and poor sleep: the effect of monoaminergic antidepressants in a pre-clinical model in rats","volume":"86","author":"Sanchez","year":"2007","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.phymed.2010.11.014_bib0215","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1001\/archpsyc.57.10.925","article-title":"Glucocorticoids and hippocampal atrophy in neuropsychiatric disorders","volume":"57","author":"Sapolsky","year":"2000","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.phymed.2010.11.014_bib0220","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1007\/s00276-005-0050-3","article-title":"Reduced hippocampal volume in drug-free depressed patients","volume":"28","author":"Saylam","year":"2006","journal-title":"Surg. Radiol. Anat."},{"key":"10.1016\/j.phymed.2010.11.014_bib0225","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1097\/FBP.0b013e3282ee2aa8","article-title":"The role of neurotrophic factors in adult hippocampal neurogenesis, antidepressant treatments and animal models of depressive-like behavior","volume":"18","author":"Schmidt","year":"2007","journal-title":"Behav. Pharmacol."},{"key":"10.1016\/j.phymed.2010.11.014_bib0230","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.febslet.2004.06.027","article-title":"Investigation on the binding and antioxidant properties of the plant flavonoid fisetin in model biomembranes","volume":"570","author":"Sengupta","year":"2004","journal-title":"FEBS Lett."},{"key":"10.1016\/j.phymed.2010.11.014_bib0235","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/0006-8993(90)91142-4","article-title":"Possible role of dopamine D1 receptor in the behavioral supersensitivity to dopamine agonists induced by chronic treatment with antidepressants","volume":"527","author":"Serra","year":"1990","journal-title":"Brain Res."},{"key":"10.1016\/j.phymed.2010.11.014_bib0240","series-title":"Pharmacology of Traditional Chinese Medicine","author":"Shen","year":"2000"},{"key":"10.1016\/j.phymed.2010.11.014_bib0245","first-page":"362","article-title":"The influence of ginsenoside Rb3 towards the NMDA induces calcium current increasing of rat hippocampus neurons","volume":"14","author":"Sheng","year":"2008","journal-title":"Chin. J. Basic Med. Tradit. Chin. Med."},{"key":"10.1016\/j.phymed.2010.11.014_bib0250","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1016\/0091-3057(82)90451-8","article-title":"Specificity of the learned helplessness model of depression","volume":"16","author":"Sherman","year":"1982","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.phymed.2010.11.014_bib0255","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/S0091-3057(96)00169-4","article-title":"Antidepressant-like effect of brain-derived neurotrophic factor (BDNF)","volume":"56","author":"Siuciak","year":"1997","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.phymed.2010.11.014_bib0260","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1002\/jat.1207","article-title":"Systems biology approaches for toxicology","volume":"27","author":"Slikker","year":"2007","journal-title":"J. Appl. Toxicol."},{"key":"10.1016\/j.phymed.2010.11.014_bib0265","doi-asserted-by":"crossref","first-page":"1621","DOI":"10.1007\/s00702-008-0115-7","article-title":"Antidepressant-like activity of zinc: further behavioral and molecular evidence","volume":"115","author":"Sowa-Kucma","year":"2008","journal-title":"J. Neural Transm."},{"key":"10.1016\/j.phymed.2010.11.014_bib0270","first-page":"2590","article-title":"Observation of curative effect about treatment of 600 examples by Seven Leaves Spirit Calmness Tablet toward neurasthenia neurosis","volume":"4","author":"Tan","year":"1999","journal-title":"Lishizhen Med. Mater. Med. Res."},{"key":"10.1016\/j.phymed.2010.11.014_bib0275","doi-asserted-by":"crossref","first-page":"1596","DOI":"10.1016\/j.jpba.2006.01.058","article-title":"Chemical characteristics for different parts of Panax notoginseng using pressurized liquid extraction and HPLC-ELSD","volume":"41","author":"Wan","year":"2006","journal-title":"J. Pharm. Biomed. Anal."},{"key":"10.1016\/j.phymed.2010.11.014_bib0280","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/j.seppur.2007.08.007","article-title":"Quantification and separation of protopanaxatriol and protopanaxadiol type saponins from Panax notoginseng with macroporous resins","volume":"60","author":"Wan","year":"2008","journal-title":"Sep. Purif. Technol."},{"key":"10.1016\/j.phymed.2010.11.014_bib0285","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1007\/s11418-005-0027-x","article-title":"Phytochemical and analytical studies of Panax notoginseng (Burk.) F.H","volume":"60","author":"Wang","year":"2006","journal-title":"Chin. J. Nat. Med."},{"key":"10.1016\/j.phymed.2010.11.014_bib0290","first-page":"14","article-title":"Effect of Chinese traditional medicine Sanchi on the expression of Nestin and BDNF after focal cerebral ischemia reperfusion injury","volume":"25","author":"Wang","year":"2007","journal-title":"J. Sichuan Tradit. Med."},{"key":"10.1016\/j.phymed.2010.11.014_bib0295","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1002\/hipo.20156","article-title":"Hippocampal neurogenesis: opposing effects of stress and antidepressant treatment","volume":"16","author":"Warner-Schmidt","year":"2006","journal-title":"Hippocampus"},{"key":"10.1016\/j.phymed.2010.11.014_bib0300","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1007\/BF00187257","article-title":"Reduction of sucrose preference by chronic unpredictable mild stress, and its restoration by a tricyclic antidepressant","volume":"93","author":"Willner","year":"1987","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.phymed.2010.11.014_bib0305","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/S0378-8741(02)00317-3","article-title":"Pharmacokinetics and bioavailability of ginsenoside Rb1 and Rg1 from Panax notoginseng in rats","volume":"84","author":"Xu","year":"2003","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.phymed.2010.11.014_bib0310","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.brainres.2004.12.044","article-title":"Inhibitory influence of ginsenoside Rb3 on activation of strychnine-sensitive glycine receptors in hippocampal neurons of rat","volume":"1037","author":"Xu","year":"2005","journal-title":"Brain Res."},{"key":"10.1016\/j.phymed.2010.11.014_bib0315","first-page":"32","article-title":"Observation of the result by using Seven Leaves Spirit Calmness Tablet to treat students\u2019 insomnia","volume":"27","author":"Zhao","year":"2005","journal-title":"Huaxia Med."}],"container-title":["Phytomedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0944711310004083?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0944711310004083?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,12,5]],"date-time":"2018-12-05T02:52:33Z","timestamp":1543978353000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0944711310004083"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,6]]},"references-count":63,"journal-issue":{"issue":"8-9","published-print":{"date-parts":[[2011,6]]}},"alternative-id":["S0944711310004083"],"URL":"https:\/\/doi.org\/10.1016\/j.phymed.2010.11.014","relation":{},"ISSN":["0944-7113"],"issn-type":[{"value":"0944-7113","type":"print"}],"subject":[],"published":{"date-parts":[[2011,6]]}}}