{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T19:07:11Z","timestamp":1791054431453,"version":"4.1.0"},"reference-count":23,"publisher":"Elsevier BV","issue":"2","content-domain":{"domain":["phytomedicinejournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Phytomedicine"],"published-print":{"date-parts":[[2014,1]]},"DOI":"10.1016\/j.phymed.2013.08.001","type":"journal-article","created":{"date-parts":[[2013,9,13]],"date-time":"2013-09-13T00:46:17Z","timestamp":1379033177000},"page":"184-194","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":21,"title":["Effect of chito-oligosaccharide on the oral absorptions of phenolic acids of Flos Lonicerae extract"],"prefix":"10.1016","volume":"21","author":[{"given":"Wei","family":"Zhou","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinjun","family":"Shan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaobin","family":"Tan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiashuang","family":"Zou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ailing","family":"Yin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baochang","family":"Cai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liuqing","family":"Di","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.phymed.2013.08.001_bib0005","doi-asserted-by":"crossref","first-page":"3181","DOI":"10.1002\/jssc.200700204","article-title":"Simultaneous determination of iridoids, phenolic acids, flavonoids, and saponins in Flos Lonicerae and Flos Lonicerae Japonicae by HPLC-DAD-ELSD coupled with principal component analysis","volume":"30","author":"Chen","year":"2007","journal-title":"J. Sep. Sci."},{"key":"10.1016\/j.phymed.2013.08.001_bib0010","series-title":"The research of fingerprints atlas about Lonicera japonica Thunb","author":"Chen","year":"2007"},{"key":"10.1016\/j.phymed.2013.08.001_bib0015","series-title":"The Pharmacopoeia of the People's Republic of China Version (2010)","author":"Chinese Pharmacopoeia Commission","year":"2010"},{"key":"10.1016\/j.phymed.2013.08.001_bib0020","first-page":"922","article-title":"Intestinal absorption of daphnetin by rats single pass perfusion in situ","volume":"44","author":"Du","year":"2009","journal-title":"Yao Xue Xue Bao"},{"key":"10.1016\/j.phymed.2013.08.001_bib0025","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.jconrel.2005.05.017","article-title":"Nitric oxide donors can enhance the intestinal transport and absorption of insulin and [Asu(1,7)]-eel calcitonin in rats","volume":"106","author":"Fetih","year":"2005","journal-title":"J. Control. Release"},{"key":"10.1016\/j.phymed.2013.08.001_bib0030","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.ijpharm.2008.03.016","article-title":"Improvement of intestinal absorption of insulin and water-soluble macromolecular compounds by chitosan oligomers in rats","volume":"359","author":"Gao","year":"2008","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.phymed.2013.08.001_bib0035","doi-asserted-by":"crossref","first-page":"1186","DOI":"10.1023\/A:1018901302450","article-title":"Chitosan as a novel nasal delivery system for peptide drugs","volume":"11","author":"Illum","year":"1994","journal-title":"Pharm. Res."},{"key":"10.1016\/j.phymed.2013.08.001_bib0040","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/S0378-5173(02)00068-6","article-title":"Intestinal paracelluar permeation enhancement with quaternised chitosan: in situ and in vitro evaluation","volume":"238","author":"Jonker","year":"2002","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.phymed.2013.08.001_bib0045","first-page":"487","article-title":"Research and comprehensive utilization of honeysuckle","volume":"28","author":"Jiao","year":"2009","journal-title":"Qilu Pharm. Aff."},{"key":"10.1016\/j.phymed.2013.08.001_bib0050","doi-asserted-by":"crossref","first-page":"2518","DOI":"10.1021\/jf035407c","article-title":"Transepithelial transport of chlorogenic acid, caffeic acid, and their colonic metabolites in intestinal Caco-2 cell monolayers","volume":"52","author":"Konishi","year":"2004","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.phymed.2013.08.001_bib0055","first-page":"88","article-title":"In vitro antiviral effect of \u201cNanosilver\u201d on influenza virus","volume":"17","author":"Mehrbod","year":"2009","journal-title":"Drug"},{"key":"10.1016\/j.phymed.2013.08.001_bib0060","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jep.2011.08.016","article-title":"Lonicera japonica Thunb.: ethnopharmacology, phytochemistry and pharmacology of an important traditional Chinese medicine","volume":"138","author":"Shang","year":"2011","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.phymed.2013.08.001_bib0065","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.addr.2006.01.003","article-title":"Tight junction modulation and its relationship to drug delivery","volume":"58","author":"Salama","year":"2006","journal-title":"Adv. Drug Deliv. Rev."},{"key":"10.1016\/j.phymed.2013.08.001_bib0070","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1002\/1520-6017(200101)90:1<38::AID-JPS5>3.0.CO;2-3","article-title":"Mono-N-Carboxymethyl Chitosan (MCC), a polyampholytic chitosan derivative, enhances the intestinal absorption of low molecular weight heparin across intestinal epithelia in vitro and in vivo","volume":"90","author":"Thanou","year":"2001","journal-title":"J. Pharm. Sci."},{"key":"10.1016\/j.phymed.2013.08.001_bib0075","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.jconrel.2006.11.002","article-title":"N-sulfonato-N, O-carboxymethylchitosan: a novel polymeric absorption enhancer for the oral delivery of macromolecular","volume":"117","author":"Thanou","year":"2007","journal-title":"J. Control. Release"},{"key":"10.1016\/j.phymed.2013.08.001_bib0080","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1211\/0022357991776976","article-title":"Enhanced permeability of insulin across the rat intestinal membrane by various absorption enhancers: their intestinal mucosal toxicity and absorption-enhancing mechanism of n-lauryl-\u03b2-d-maltopyranoside","volume":"51","author":"Uchiyama","year":"1999","journal-title":"J. Pharm. Pharmacol."},{"key":"10.1016\/j.phymed.2013.08.001_bib0085","series-title":"Studies on antiviral effect and immunopotentiating activity of Lonicera japonica Thunb. and flos lonicerae in vitro","author":"Wang","year":"2008"},{"key":"10.1016\/j.phymed.2013.08.001_bib0090","series-title":"Study of effective substances screening for flos lonicerae based on the \u201cspectrum-effect\u201d combination","author":"Wang","year":"2010"},{"key":"10.1016\/j.phymed.2013.08.001_bib0095","series-title":"Flos Lonicerae Japonicae. Chromatographic Fingerprint Analysis of Herbal Medicines","first-page":"587","author":"Wagner","year":"2011"},{"key":"10.1016\/j.phymed.2013.08.001_bib0100","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.1111\/j.2042-7158.1996.tb03937.x","article-title":"Effectiveness and toxicity screening of various absorption enhancers in the rat small intestine: effects of absorption enhancers on the intestinal absorption of phenol red and the release of protein and phospholipids from the intestinal membrane","volume":"48","author":"Yamamoto","year":"1996","journal-title":"J. Pharm. Pharmacol."},{"key":"10.1016\/j.phymed.2013.08.001_bib0105","series-title":"Novel patterns of efficient components recognition and quality control for flos lonicerae japonicae based on constituent knock-out\/knock-in","author":"Zhang","year":"2011"},{"key":"10.1016\/j.phymed.2013.08.001_bib0110","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.phymed.2012.09.014","article-title":"Improvement of intestinal absorption of forsythoside A in weeping forsythia extract by various absorption enhancers based on tight junctions","volume":"20","author":"Zhou","year":"2012","journal-title":"Phytomedicine"},{"key":"10.1016\/j.phymed.2013.08.001_bib0115","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1038\/aps.2012.58","article-title":"Intestinal absorption of forsythoside A in in situ single-pass intestinal perfusion and in vitro Caco-2 cell models","volume":"33","author":"Zhou","year":"2012","journal-title":"Acta Pharmacol. Sin."}],"container-title":["Phytomedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0944711313002833?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0944711313002833?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,10,13]],"date-time":"2018-10-13T04:23:32Z","timestamp":1539404612000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0944711313002833"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,1]]},"references-count":23,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2014,1]]}},"alternative-id":["S0944711313002833"],"URL":"https:\/\/doi.org\/10.1016\/j.phymed.2013.08.001","relation":{},"ISSN":["0944-7113"],"issn-type":[{"value":"0944-7113","type":"print"}],"subject":[],"published":{"date-parts":[[2014,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effect of chito-oligosaccharide on the oral absorptions of phenolic acids of Flos Lonicerae extract","name":"articletitle","label":"Article Title"},{"value":"Phytomedicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.phymed.2013.08.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier GmbH. All rights reserved.","name":"copyright","label":"Copyright"}]}}