{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T01:01:41Z","timestamp":1785200501510,"version":"3.55.0"},"reference-count":17,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,3,1]],"date-time":"2019-03-01T00:00:00Z","timestamp":1551398400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100005672","name":"Apoio ao Desenvolvimento do Ensino, Ci\u00eancia e Tecnologia do Estado de Mato Grosso do Sul","doi-asserted-by":"publisher","award":["59\/300.046\/2015"],"award-info":[{"award-number":["59\/300.046\/2015"]}],"id":[{"id":"10.13039\/501100005672","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005672","name":"FUNDECT","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005672","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"CNPq","doi-asserted-by":"publisher","award":["449464\/2014-8"],"award-info":[{"award-number":["449464\/2014-8"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Phytomedicine"],"published-print":{"date-parts":[[2019,3]]},"DOI":"10.1016\/j.phymed.2018.08.014","type":"journal-article","created":{"date-parts":[[2018,8,11]],"date-time":"2018-08-11T02:24:15Z","timestamp":1533954255000},"page":"74-82","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"special_numbering":"C","title":["Influence of Luehea divaricata Mart. extracts on peripheral vascular resistance and the role of nitric oxide and both Ca+2-sensitive and Kir6.1 ATP-sensitive K+ channels in the vasodilatory effects of isovitexin on isolated perfused mesenteric beds"],"prefix":"10.1016","volume":"56","author":[{"given":"Cleide Adriane Signor","family":"Tirloni","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rhanany Alan Calloi","family":"Palozi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maysa Isernhagen","family":"Schaedler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucas Pires","family":"Guarnier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aniely Oliveira","family":"Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcia Arantes","family":"Marques","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3433-5098","authenticated-orcid":false,"given":"Francielly Mour\u00e3o","family":"Gasparotto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emerson Luiz Botelho","family":"Louren\u00e7o","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lauro Mera","family":"de Souza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arquimedes","family":"Gasparotto Junior","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.phymed.2018.08.014_bib0001","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/j.indcrop.2014.08.038","article-title":"Luehea divaricata Mart. anticholinesterase and antioxidant activity in a Caenorhabditis elegans model system","volume":"62","author":"Arantes","year":"2014","journal-title":"Ind. Crops Prod"},{"key":"10.1016\/j.phymed.2018.08.014_bib0002","doi-asserted-by":"crossref","first-page":"1424","DOI":"10.1152\/ajpcell.1996.271.5.C1424","article-title":"Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly","volume":"271","author":"Beckman","year":"1996","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.phymed.2018.08.014_bib0003","doi-asserted-by":"crossref","DOI":"10.1155\/2012\/272749","article-title":"Ethnopharmacology of medicinal plants of the pantanal region (Mato Grosso, Brazil)","author":"Bieski","year":"2012","journal-title":"Evidence Based Complementary Altern. Med."},{"issue":"12","key":"10.1016\/j.phymed.2018.08.014_bib0020","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1111\/j.1440-1681.1996.tb01172.x","article-title":"Potassium channels in vascular smooth muscle","volume":"23","author":"Brayden","year":"1996","journal-title":"Clin. Exp. Pharmacol. Physiol."},{"key":"10.1016\/j.phymed.2018.08.014_bib0004","doi-asserted-by":"crossref","DOI":"10.1155\/2015\/723431","article-title":"Protective effects of aqueous extract of Luehea divaricata against behavioral and oxidative changes induced by 3-nitropropionic acid in rats","author":"Courtes","year":"2015","journal-title":"Evidence Based Complementary Altern. Med."},{"issue":"4","key":"10.1016\/j.phymed.2018.08.014_bib0005","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1111\/bju.13105","article-title":"Pharmacological characterisation of the relaxation induced by the soluble guanylate cyclase activator, BAY 60-2770 in rabbit corpus cavernosum","volume":"116","author":"Estancial","year":"2015","journal-title":"BJU Int."},{"issue":"1","key":"10.1016\/j.phymed.2018.08.014_bib0006","doi-asserted-by":"crossref","first-page":"16","DOI":"10.4238\/vol10-1gmr982","article-title":"Mutagenic potential and modulatory effects of the medicinal plant Luehea divaricata (Malvaceae) in somatic cells of Drosophila melanogaster: SMART\/wing","volume":"10","author":"Fel\u00edcio","year":"2011","journal-title":"Genet. Mol. Res."},{"issue":"9","key":"10.1016\/j.phymed.2018.08.014_bib0007","doi-asserted-by":"crossref","first-page":"e108","DOI":"10.1161\/ATVBAHA.117.309813","article-title":"Endothelial functions","volume":"37","author":"Godo","year":"2017","journal-title":"Arterioscler. Thromb Vasc. Biol."},{"key":"10.1016\/j.phymed.2018.08.014_bib0008","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.fitote.2016.09.011","article-title":"A review on the pharmacological effects of vitexin and isovitexin","volume":"115","author":"He","year":"2016","journal-title":"Fitoterapia"},{"key":"10.1016\/j.phymed.2018.08.014_bib0009","series-title":"Manual De Identifica\u00e7\u00e3o e Cultivo De Plantas Arb\u00f3reas Nativas Do Brasil: \u00e1rvores Brasileiras","author":"Lorenzi","year":"1992"},{"key":"10.1016\/j.phymed.2018.08.014_bib0010","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1113\/jphysiol.1965.sp007572","article-title":"The effect of sympathetic nerve stimulation of vasoconstrictor responses in perfused mesenteric blood vessels of the rat","volume":"177","author":"McGregor","year":"1965","journal-title":"J. Physiol."},{"issue":"2","key":"10.1016\/j.phymed.2018.08.014_bib0011","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1002\/cphy.c150047","article-title":"Renal nerves and long-term control of arterial pressure","volume":"7","author":"Osborn","year":"2017","journal-title":"Compr. Physiol."},{"issue":"1","key":"10.1016\/j.phymed.2018.08.014_bib0012","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1161\/HYPERTENSIONAHA.117.09870","article-title":"Evidence for a role of vascular endothelium in the control of arterial wall viscosity in humans","volume":"71","author":"Roca","year":"2018","journal-title":"Hypertension"},{"issue":"5","key":"10.1016\/j.phymed.2018.08.014_bib0013","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1590\/S0100-40422005000500020","article-title":"Chemical constituents of Luehea divaricata Mart. (TILIACEAE)","volume":"28","author":"Tanaka","year":"2005","journal-title":"Quim. Nova"},{"key":"10.1016\/j.phymed.2018.08.014_bib0014","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.jep.2017.09.020","article-title":"Ethnopharmacological approaches to kidney disease-prospecting an indigenous species from Brazilian Pantanal","volume":"211","author":"Tirloni","year":"2017","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.phymed.2018.08.014_bib0015","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1007\/978-3-319-55330-6_18","article-title":"Nitrite-nitric oxide signaling and cardioprotection","volume":"982","author":"Totzeck","year":"2017","journal-title":"Adv. Exp. Med. Biol"},{"issue":"2","key":"10.1016\/j.phymed.2018.08.014_bib0016","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1002\/cphy.c160011","article-title":"Smooth muscle ion channels and regulation of vascular tone in resistance arteries and arterioles","volume":"7","author":"Tykocki","year":"2017","journal-title":"Compr. Physiol."}],"container-title":["Phytomedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0944711318302794?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0944711318302794?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,8,8]],"date-time":"2019-08-08T16:39:25Z","timestamp":1565282365000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0944711318302794"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,3]]},"references-count":17,"alternative-id":["S0944711318302794"],"URL":"https:\/\/doi.org\/10.1016\/j.phymed.2018.08.014","relation":{},"ISSN":["0944-7113"],"issn-type":[{"value":"0944-7113","type":"print"}],"subject":[],"published":{"date-parts":[[2019,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Influence of Luehea divaricata Mart. extracts on peripheral vascular resistance and the role of nitric oxide and both Ca+2-sensitive and Kir6.1 ATP-sensitive K+ channels in the vasodilatory effects of isovitexin on isolated perfused mesenteric beds","name":"articletitle","label":"Article Title"},{"value":"Phytomedicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.phymed.2018.08.014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier GmbH. All rights reserved.","name":"copyright","label":"Copyright"}]}}