{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T16:06:34Z","timestamp":1790870794391,"version":"4.1.0"},"reference-count":53,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Phytomedicine"],"published-print":{"date-parts":[[2024,10]]},"DOI":"10.1016\/j.phymed.2024.155923","type":"journal-article","created":{"date-parts":[[2024,7,29]],"date-time":"2024-07-29T06:20:46Z","timestamp":1722234046000},"page":"155923","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"special_numbering":"C","title":["Radix rehmanniae praeparata extracts ameliorate hepatic ischemia-reperfusion injury by reversing LRP1-NOTCH1-C\/EBP\u03b2 axis-mediated senescence fate of LSECs"],"prefix":"10.1016","volume":"133","author":[{"given":"Yinhao","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiaorong","family":"Qu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ranyi","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kexin","family":"Jia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guifang","family":"Fan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fanghong","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruiyu","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianan","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0291-5856","authenticated-orcid":false,"given":"Xiaojiaoyang","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.phymed.2024.155923_bib0001","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1002\/ame2.12034","article-title":"Rehmannia glutinosa exhibits anti-aging effect through maintaining the quiescence and decreasing the senescence of hematopoietic stem cells","volume":"1","author":"Bai","year":"2018","journal-title":"Anim. Models Exp. Med."},{"key":"10.1016\/j.phymed.2024.155923_bib0002","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.hbpd.2022.08.009","article-title":"Polydatin ameliorates hepatic ischemia-reperfusion injury by modulating macrophage polarization","volume":"23","author":"Bao","year":"2024","journal-title":"Hepatobiliary Pancreat. Dis. Int."},{"key":"10.1016\/j.phymed.2024.155923_bib0003","doi-asserted-by":"crossref","DOI":"10.1016\/j.devcel.2021.09.015","article-title":"Low-density-lipoprotein-receptor-related protein 1 mediates Notch pathway activation","volume":"56","author":"Bian","year":"2021","journal-title":"Dev. Cell"},{"key":"10.1016\/j.phymed.2024.155923_bib0004","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1101\/gad.337394.120","article-title":"Blunting senescence boosts liver regeneration","volume":"34","author":"Birch","year":"2020","journal-title":"Genes Dev."},{"key":"10.1016\/j.phymed.2024.155923_bib0005","doi-asserted-by":"crossref","first-page":"1565","DOI":"10.1101\/gad.343129.120","article-title":"Senescence and the SASP: many therapeutic avenues","volume":"34","author":"Birch","year":"2020","journal-title":"Genes Dev."},{"key":"10.1016\/j.phymed.2024.155923_bib0006","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.aan1230","article-title":"TGF\u03b2 inhibition restores a regenerative response in acute liver injury by suppressing paracrine senescence","volume":"10","author":"Bird","year":"2018","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.phymed.2024.155923_bib0007","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0253475","article-title":"Iron overload inhibits BMP\/SMAD and IL-6\/STAT3 signaling to hepcidin in cultured hepatocytes","volume":"16","author":"Charlebois","year":"2021","journal-title":"PLoS One"},{"key":"10.1016\/j.phymed.2024.155923_bib0008","doi-asserted-by":"crossref","first-page":"111","DOI":"10.4149\/gpb-2018044","article-title":"Catalpol attenuates lipopolysaccharide-induced inflammatory responses in BV2 microglia through inhibiting the TLR4-mediated NF-\u03baB pathway","volume":"38","author":"Choi","year":"2019","journal-title":"Gen. Physiol. Biophys."},{"key":"10.1016\/j.phymed.2024.155923_bib0009","doi-asserted-by":"crossref","first-page":"3333","DOI":"10.1007\/s00018-020-03746-x","article-title":"Senescence under appraisal: hopes and challenges revisited","volume":"78","author":"Davan-Wetton","year":"2021","journal-title":"Cell Mol. Life Sci."},{"key":"10.1016\/j.phymed.2024.155923_bib0010","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1038\/s41580-020-00314-w","article-title":"Cellular senescence in ageing: from mechanisms to therapeutic opportunities","volume":"22","author":"Di Micco","year":"2021","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.phymed.2024.155923_bib0011","doi-asserted-by":"crossref","first-page":"3368","DOI":"10.1039\/D1FO03952K","article-title":"N-Acetylcysteine alleviates high fat diet-induced hepatic steatosis and liver injury via regulating the intestinal microecology in mice","volume":"13","author":"Ding","year":"2022","journal-title":"Food Funct."},{"key":"10.1016\/j.phymed.2024.155923_bib0012","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1038\/s43587-022-00348-z","article-title":"Age-related liver endothelial zonation triggers steatohepatitis by inactivating pericentral endothelium-derived C-kit","volume":"3","author":"Duan","year":"2023","journal-title":"Nat. Aging"},{"key":"10.1016\/j.phymed.2024.155923_bib0013","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1002\/hep.32209","article-title":"Shear stress-induced cellular senescence blunts liver regeneration through Notch-sirtuin 1-P21\/P16 axis","volume":"75","author":"Duan","year":"2022","journal-title":"Hepatology"},{"key":"10.1016\/j.phymed.2024.155923_bib0014","doi-asserted-by":"crossref","DOI":"10.3390\/ijms23020652","article-title":"The potential role of cellular senescence in non-alcoholic fatty liver disease","volume":"23","author":"Engelmann","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.phymed.2024.155923_bib0015","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1038\/s41575-020-00411-3","article-title":"Role of liver sinusoidal endothelial cells in liver diseases","volume":"18","author":"Gracia-Sancho","year":"2021","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"key":"10.1016\/j.phymed.2024.155923_bib0016","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1038\/ncb3397","article-title":"NOTCH1 mediates a switch between two distinct secretomes during senescence","volume":"18","author":"Hoare","year":"2016","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.phymed.2024.155923_bib0017","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1080\/15384101.2016.1248730","article-title":"NOTCH and the 2 SASPs of senescence","volume":"16","author":"Hoare","year":"2017","journal-title":"Cell Cycle"},{"key":"10.1016\/j.phymed.2024.155923_bib0018","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1038\/s41419-020-2648-0","article-title":"Inhibition of miR-450b-5p ameliorates hepatic ischemia\/reperfusion injury via targeting CRYAB","volume":"11","author":"Huang","year":"2020","journal-title":"Cell Death. Dis."},{"key":"10.1016\/j.phymed.2024.155923_bib0019","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1080\/09168451.2019.1569495","article-title":"MicroRNA-125b protects liver from ischemia\/reperfusion injury via inhibiting TRAF6 and NF-\u03baB pathway","volume":"83","author":"Huang","year":"2019","journal-title":"Biosci. Biotechnol. Biochem."},{"key":"10.1016\/j.phymed.2024.155923_bib0020","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1038\/s42003-021-01936-2","article-title":"Mechanical homeostasis of liver sinusoid is involved in the initiation and termination of liver regeneration","volume":"4","author":"Ishikawa","year":"2021","journal-title":"Commun. Biol."},{"key":"10.1016\/j.phymed.2024.155923_bib0021","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2023.115809","article-title":"Progress of research into the pharmacological effect and clinical application of the traditional Chinese medicine Rehmanniae Radix","volume":"168","author":"Jia","year":"2023","journal-title":"Biomed. PharmacOther"},{"key":"10.1016\/j.phymed.2024.155923_bib0022","doi-asserted-by":"crossref","first-page":"4967","DOI":"10.7150\/ijbs.87332","article-title":"Acteoside ameliorates hepatic ischemia-reperfusion injury via reversing the senescent fate of liver sinusoidal endothelial cells and restoring compromised sinusoidal networks","volume":"19","author":"Jia","year":"2023","journal-title":"Int. J. Biol. Sci."},{"key":"10.1016\/j.phymed.2024.155923_bib0023","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1186\/s12915-022-01272-9","article-title":"Dopamine D1- and D2-like receptors oppositely regulate lifespan via a dietary restriction mechanism in Caenorhabditis elegans","volume":"20","author":"Jiang","year":"2022","journal-title":"BMC Biol."},{"key":"10.1016\/j.phymed.2024.155923_bib0024","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1016\/j.hbpd.2022.04.004","article-title":"Exosome is involved in liver graft protection after remote ischemia reperfusion conditioning","volume":"22","author":"Li","year":"2023","journal-title":"Hepatobiliary Pancreat. Dis. Int."},{"key":"10.1016\/j.phymed.2024.155923_bib0025","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2021.107928","article-title":"FBXW5 aggravates hepatic ischemia\/reperfusion injury via promoting phosphorylation of ASK1 in a TRAF6-dependent manner","volume":"99","author":"Li","year":"2021","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.phymed.2024.155923_bib0026","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1186\/s13578-023-01014-6","article-title":"Aging aggravates acetaminophen-induced acute liver injury and inflammation through inordinate C\/EBP\u03b1-BMP9 crosstalk","volume":"13","author":"Liu","year":"2023","journal-title":"Cell Biosci."},{"key":"10.1016\/j.phymed.2024.155923_bib0027","doi-asserted-by":"crossref","DOI":"10.1002\/cbdv.202000341","article-title":"Phytochemical profiles and antioxidant activity of rehmannia glutinosa from different production locations","volume":"17","author":"Liu","year":"2020","journal-title":"Chem. Biodivers."},{"key":"10.1016\/j.phymed.2024.155923_bib0028","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2022.113834","article-title":"Si-Wu-Tang ameliorates bile duct ligation-induced liver fibrosis via modulating immune environment","volume":"155","author":"Ma","year":"2022","journal-title":"Biomed. PharmacOther"},{"key":"10.1016\/j.phymed.2024.155923_bib0029","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1016\/j.jhep.2016.04.018","article-title":"Sinusoidal communication in liver fibrosis and regeneration","volume":"65","author":"Marrone","year":"2016","journal-title":"J. Hepatol."},{"key":"10.1016\/j.phymed.2024.155923_bib0030","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1038\/nrm3823","article-title":"Cellular senescence: from physiology to pathology","volume":"15","author":"Mu\u00f1oz-Esp\u00edn","year":"2014","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.phymed.2024.155923_bib0031","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1002\/hep.30834","article-title":"The role of senescence in the development of nonalcoholic fatty liver disease and progression to nonalcoholic steatohepatitis","volume":"71","author":"Papatheodoridi","year":"2020","journal-title":"Hepatology"},{"key":"10.1016\/j.phymed.2024.155923_bib0032","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/S2095-4964(14)60044-3","article-title":"Liuwei Dihuang, a traditional Chinese herbal formula, suppresses chronic inflammation and oxidative stress in obese rats","volume":"12","author":"Perry","year":"2014","journal-title":"J. Integr. Med."},{"key":"10.1016\/j.phymed.2024.155923_bib0033","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1101\/gad.332643.119","article-title":"The senotherapeutic drug ABT-737 disrupts aberrant p21 expression to restore liver regeneration in adult mice","volume":"34","author":"Ritschka","year":"2020","journal-title":"Genes Dev."},{"key":"10.1016\/j.phymed.2024.155923_bib0034","doi-asserted-by":"crossref","DOI":"10.1016\/j.exger.2019.110752","article-title":"Regulation of senescence and the SASP by the transcription factor C\/EBP\u03b2","volume":"128","author":"Salotti","year":"2019","journal-title":"Exp. Gerontol."},{"key":"10.1016\/j.phymed.2024.155923_bib0035","doi-asserted-by":"crossref","first-page":"1594","DOI":"10.1002\/lt.21864","article-title":"Exaggerated up-regulation of tumor necrosis factor alpha-dependent apoptosis in the older mouse liver following reperfusion injury: targeting liver protective strategies to patient age","volume":"15","author":"Selzner","year":"2009","journal-title":"Liver Transpl."},{"key":"10.1016\/j.phymed.2024.155923_bib0036","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1093\/gerona\/glq108","article-title":"Age-related changes in scavenger receptor-mediated endocytosis in rat liver sinusoidal endothelial cells","volume":"65","author":"Simon-Santamaria","year":"2010","journal-title":"J. Gerontol. Biol. Sci. Med. Sci."},{"key":"10.1016\/j.phymed.2024.155923_bib0037","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2019.03.104","article-title":"Notch signaling mediates secondary senescence","volume":"27","author":"Teo","year":"2019","journal-title":"Cell Rep."},{"key":"10.1016\/j.phymed.2024.155923_bib0038","doi-asserted-by":"crossref","first-page":"2119","DOI":"10.1002\/hep.31215","article-title":"Transcriptional dynamics of hepatic sinusoid-associated cells after liver injury","volume":"72","author":"Terkelsen","year":"2020","journal-title":"Hepatology"},{"key":"10.1016\/j.phymed.2024.155923_bib0039","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1002\/hep.30508","article-title":"The role of complement in liver injury, regeneration, and transplantation","volume":"70","author":"Thorgersen","year":"2019","journal-title":"Hepatology"},{"key":"10.1016\/j.phymed.2024.155923_bib0040","doi-asserted-by":"crossref","DOI":"10.1155\/2020\/6708061","article-title":"Catalpol attenuates hepatic steatosis by regulating lipid metabolism via AMP-activated protein kinase activation","volume":"2020","author":"Tian","year":"2020","journal-title":"Biomed. Res. Int."},{"key":"10.1016\/j.phymed.2024.155923_bib0041","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1080\/14728222.2021.1992385","article-title":"Cellular senescence in liver fibrosis: implications for age-related chronic liver diseases","volume":"25","author":"Udomsinprasert","year":"2021","journal-title":"Expert Opin. Ther. Targets"},{"key":"10.1016\/j.phymed.2024.155923_bib0042","doi-asserted-by":"crossref","first-page":"3618","DOI":"10.1016\/j.apsb.2022.03.014","article-title":"Inhibition of ASCT2 induces hepatic stellate cell senescence with modified proinflammatory secretome through an IL-1\u03b1\/NF-\u03baB feedback pathway to inhibit liver fibrosis","volume":"12","author":"Wang","year":"2022","journal-title":"Acta Pharm. Sin. B"},{"key":"10.1016\/j.phymed.2024.155923_bib0043","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2021.111305","article-title":"The nephroprotective effects and mechanisms of rehmapicrogenin include ROS inhibition via an oestrogen-like pathway both in vivo and in vitro","volume":"138","author":"Wang","year":"2021","journal-title":"Biomed. PharmacOther"},{"key":"10.1016\/j.phymed.2024.155923_bib0044","article-title":"Catalpol protects against pulmonary fibrosis through inhibiting TGF-\u03b21\/Smad3 and Wnt\/\u03b2-catenin signaling pathways","volume":"11","author":"Yang","year":"2020","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.phymed.2024.155923_bib0045","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.aat9284","article-title":"Hyaluronan synthase 2-mediated hyaluronan production mediates Notch1 activation and liver fibrosis","volume":"11","author":"Yang","year":"2019","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.phymed.2024.155923_bib0046","first-page":"902","article-title":"Radix Rehmanniae Praeparata aqueous extract improves hepatic ischemia\/reperfusion injury by restoring intracellular iron homeostasis","volume":"20","author":"Yinhao","year":"2023","journal-title":"Chin. J. Nat. Med."},{"key":"10.1016\/j.phymed.2024.155923_bib0047","first-page":"1","article-title":"Radix Rehmanniae Praeparata aqueous extract improves hepatic ischemia\/reperfusion injury by restoring intracellular iron homeostasi","volume":"21","author":"Yinhao Zhang","year":"2023","journal-title":"Chin. J. Nat. Med."},{"key":"10.1016\/j.phymed.2024.155923_bib0048","doi-asserted-by":"crossref","DOI":"10.3390\/molecules24244592","article-title":"Study of the effect of neutral polysaccharides from rehmannia glutinosa on lifespan of caenorhabditis elegans","volume":"24","author":"Yuan","year":"2019","journal-title":"Molecules"},{"key":"10.1016\/j.phymed.2024.155923_bib0049","doi-asserted-by":"crossref","DOI":"10.1016\/j.mad.2021.111572","article-title":"Hepatic stellate cell senescence in liver fibrosis: characteristics, mechanisms and perspectives","volume":"199","author":"Zhang","year":"2021","journal-title":"Mech. Ageing Dev."},{"key":"10.1016\/j.phymed.2024.155923_bib0050","first-page":"1","article-title":"Radix Rehmanniae Praeparata aqueous extract improves hepatic ischemia\/reperfusion injury by restoring intracellular iron homeostasis","volume":"21","author":"Zhang","year":"2023","journal-title":"Chin. J. Nat. Med."},{"key":"10.1016\/j.phymed.2024.155923_bib0051","doi-asserted-by":"crossref","DOI":"10.1155\/2018\/2876350","article-title":"Activating the PGC-1\u03b1\/TERT pathway by catalpol ameliorates atherosclerosis via modulating ROS production, DNA damage, and telomere function: implications on mitochondria and telomere link","author":"Zhang","year":"2018","journal-title":"Oxid. Med. Cell Longev."},{"key":"10.1016\/j.phymed.2024.155923_bib0052","article-title":"Aurantio-obtusin attenuates non-alcoholic fatty liver disease through AMPK-mediated autophagy and fatty acid oxidation pathways","volume":"12","author":"Zhou","year":"2021","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.phymed.2024.155923_bib0053","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1186\/s12931-021-01620-3","article-title":"Resveratrol attenuates cigarette smoke induced endothelial apoptosis by activating Notch1 signaling mediated autophagy","volume":"22","author":"Zong","year":"2021","journal-title":"Respir. Res."}],"container-title":["Phytomedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0944711324005816?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0944711324005816?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,8,28]],"date-time":"2024-08-28T17:23:13Z","timestamp":1724865793000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0944711324005816"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10]]},"references-count":53,"alternative-id":["S0944711324005816"],"URL":"https:\/\/doi.org\/10.1016\/j.phymed.2024.155923","relation":{},"ISSN":["0944-7113"],"issn-type":[{"value":"0944-7113","type":"print"}],"subject":[],"published":{"date-parts":[[2024,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Radix rehmanniae praeparata extracts ameliorate hepatic ischemia-reperfusion injury by reversing LRP1-NOTCH1-C\/EBP\u03b2 axis-mediated senescence fate of LSECs","name":"articletitle","label":"Article Title"},{"value":"Phytomedicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.phymed.2024.155923","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier GmbH. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"155923"}}