{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T20:37:02Z","timestamp":1793738222165,"version":"4.6.1"},"reference-count":41,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82073978"],"award-info":[{"award-number":["82073978"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82104441"],"award-info":[{"award-number":["82104441"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81,725,024"],"award-info":[{"award-number":["81,725,024"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Phytomedicine"],"published-print":{"date-parts":[[2025,1]]},"DOI":"10.1016\/j.phymed.2024.156260","type":"journal-article","created":{"date-parts":[[2024,11,14]],"date-time":"2024-11-14T17:31:45Z","timestamp":1731605505000},"page":"156260","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":59,"special_numbering":"C","title":["Salvianolic acid B alleviated myocardial ischemia-reperfusion injury via modulating SIRT3-mediated crosstalk between mitochondrial ROS and NLRP3"],"prefix":"10.1016","volume":"136","author":[{"given":"Xiao-Hong","family":"Wei","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xue-Fen","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qian","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gui-Yang","family":"Xia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin-Yu","family":"Chu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huan","family":"Xia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheng","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong-Cai","family":"Shang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.phymed.2024.156260_bib0001","doi-asserted-by":"crossref","unstructured":"Chen, M.L., Zhu, X.H., Ran, L., Lang, H.D., Yi, L., Mi, M.T., 2017. Trimethylamine-N-oxide induces vascular inflammation by activating the NLRP3 inflammasome through the SIRT3-SOD2-mtROS signaling pathway. 6. https:\/\/doi.org\/10.1161\/jaha.117.006347.","DOI":"10.1161\/JAHA.117.006347"},{"key":"10.1016\/j.phymed.2024.156260_bib0002","doi-asserted-by":"crossref","unstructured":"Chouchani, E.T., Pell, V.R., Gaude, E., Aksentijevi\u0107, D., Sundier, S.Y., Robb, E.L., Logan, A., Nadtochiy, S.M., Ord, E.N.J., Smith, A.C., Eyassu, F., Shirley, R., Hu, C.H., Dare, A.J., James, A.M., Rogatti, S., Hartley, R.C., Eaton, S., Costa, A.S.H., Brookes, P.S., Davidson, S.M., Duchen, M.R., Saeb-Parsy, K., Shattock, M.J., Robinson, A.J., Work, L.M., Frezza, C., Krieg, T., Murphy, M.P., 2014. Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS. 515, 431\u2013435. https:\/\/doi.org\/10.1038\/nature13909.","DOI":"10.1038\/nature13909"},{"key":"10.1016\/j.phymed.2024.156260_bib0003","doi-asserted-by":"crossref","unstructured":"Coll, R.C., Robertson, A.A., Chae, J.J., Higgins, S.C., Mu\u00f1oz-Planillo, R., Inserra, M.C., Vetter, I., Dungan, L.S., Monks, B.G., Stutz, A., Croker, D.E., Butler, M.S., Haneklaus, M., Sutton, C.E., N\u00fa\u00f1ez, G., Latz, E., Kastner, D.L., Mills, K.H., Masters, S.L., Schroder, K., Cooper, M.A., O'Neill, L.A., 2015. A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases. 21, 248\u2013255. https:\/\/doi.org\/10.1038\/nm.3806.","DOI":"10.1038\/nm.3806"},{"key":"10.1016\/j.phymed.2024.156260_bib0004","doi-asserted-by":"crossref","unstructured":"Cui, M., Atmanli, A., Morales, M.G., Tan, W., Chen, K., Xiao, X., Xu, L., Liu, N., Bassel-Duby, R., Olson, E.N., 2021. Nrf1 promotes heart regeneration and repair by regulating proteostasis and redox balance. 12, 5270. https:\/\/doi.org\/10.1038\/s41467-021-25653-w.","DOI":"10.1038\/s41467-021-25653-w"},{"key":"10.1016\/j.phymed.2024.156260_bib0005","doi-asserted-by":"crossref","unstructured":"Darwesh, A.M., Bassiouni, W., Adebesin, A.M., Mohammad, A.S., Falck, J.R., Seubert, J.M., 2020. A synthetic epoxydocosapentaenoic acid analogue ameliorates cardiac ischemia\/reperfusion injury: the involvement of the Sirtuin 3-NLRP3 pathway. 21. https:\/\/doi.org\/10.3390\/ijms21155261.","DOI":"10.3390\/ijms21155261"},{"key":"10.1016\/j.phymed.2024.156260_bib0006","doi-asserted-by":"crossref","unstructured":"Ding, X., Zhu, C., Wang, W., Li, M., Ma, C., Gao, B., 2024. SIRT1 is a regulator of autophagy: implications for the progression and treatment of myocardial ischemia-reperfusion. 199, 106957. https:\/\/doi.org\/10.1016\/j.phrs.2023.106957.","DOI":"10.1016\/j.phrs.2023.106957"},{"key":"10.1016\/j.phymed.2024.156260_bib0007","doi-asserted-by":"crossref","unstructured":"Du, K., Ramachandran, A., Weemhoff, J.L., Woolbright, B.L., Jaeschke, A.H., Chao, X., Ding, W.X., Jaeschke, H., 2019. Mito-tempo protects against acute liver injury but induces limited secondary apoptosis during the late phase of acetaminophen hepatotoxicity. 93, 163\u2013178. https:\/\/doi.org\/10.1007\/s00204-018-2331-8.","DOI":"10.1007\/s00204-018-2331-8"},{"key":"10.1016\/j.phymed.2024.156260_bib0008","doi-asserted-by":"crossref","unstructured":"Eltzschig, H.K., Eckle, T., 2011. Ischemia and reperfusion\u2013from mechanism to translation. 17, 1391\u20131401. https:\/\/doi.org\/10.1038\/nm.2507.","DOI":"10.1038\/nm.2507"},{"key":"10.1016\/j.phymed.2024.156260_bib0009","doi-asserted-by":"crossref","unstructured":"Feng, J., Chen, X., Liu, R., Cao, C., Zhang, W., Zhao, Y., Nie, S., 2018. Melatonin protects against myocardial ischemia-reperfusion injury by elevating Sirtuin3 expression and manganese superoxide dismutase activity. 52, 840\u2013849. https:\/\/doi.org\/10.1080\/10715762.2018.1461215.","DOI":"10.1080\/10715762.2018.1461215"},{"key":"10.1016\/j.phymed.2024.156260_bib0010","doi-asserted-by":"crossref","unstructured":"Guo, S.S., Wang, Z.G., 2022. Salvianolic acid B from Salvia miltiorrhiza bunge: A potential antitumor agent. 13, 1042745. https:\/\/doi.org\/10.3389\/fphar.2022.1042745.","DOI":"10.3389\/fphar.2022.1042745"},{"key":"10.1016\/j.phymed.2024.156260_bib0011","doi-asserted-by":"crossref","unstructured":"Hu, J., Liu, T., Fu, F., Cui, Z., Lai, Q., Zhang, Y., Yu, B., Liu, F., Kou, J., Li, F., 2022. Omentin1 ameliorates myocardial ischemia-induced heart failure via SIRT3\/FOXO3a-dependent mitochondrial dynamical homeostasis and mitophagy. 20, 447. https:\/\/doi.org\/10.1186\/s12967-022-03642-x.","DOI":"10.1186\/s12967-022-03642-x"},{"key":"10.1016\/j.phymed.2024.156260_bib0012","doi-asserted-by":"crossref","unstructured":"Huang, D.D., Wei, X.H., Mu, H.N., Pan, C.S., Li, Q., Hu, B.H., Chang, X., Yan, L., Fan, J.Y., Liu, Y.Y., Luo, J.Y., Han, J.Y., 2019. Total salvianolic acid injection prevents ischemia\/reperfusion-induced myocardial injury via antioxidant mechanism involving mitochondrial respiratory chain through the upregulation of sirtuin1 and sirtuin3. 51, 745\u2013756. https:\/\/doi.org\/10.1097\/shk.0000000000001185.","DOI":"10.1097\/SHK.0000000000001185"},{"key":"10.1016\/j.phymed.2024.156260_bib0013","doi-asserted-by":"crossref","unstructured":"Huang, Y., Xu, W., Zhou, R., 2021. NLRP3 inflammasome activation and cell death. 18, 2114\u20132127. https:\/\/doi.org\/10.1038\/s41423-021-00740-6.","DOI":"10.1038\/s41423-021-00740-6"},{"key":"10.1016\/j.phymed.2024.156260_bib0014","doi-asserted-by":"crossref","unstructured":"Ichihara, G., Katsumata, Y., Sugiura, Y., Matsuoka, Y., Maeda, R., Endo, J., Anzai, A., Shirakawa, K., Moriyama, H., Kitakata, H., Hiraide, T., Goto, S., Ko, S., Iwasawa, Y., Sugai, K., Daigo, K., Goto, S., Sato, K., Yamada, K.I., Suematsu, M., Ieda, M., Sano, M., 2023. MRP1-dependent extracellular release of glutathione induces cardiomyocyte ferroptosis after ischemia-reperfusion. 133, 861\u2013876. https:\/\/doi.org\/10.1161\/circresaha.123.323517.","DOI":"10.1161\/CIRCRESAHA.123.323517"},{"key":"10.1016\/j.phymed.2024.156260_bib0015","doi-asserted-by":"crossref","unstructured":"Jia, Y., Pan, J., 2024. CKLF1, transcriptionally activated by FOXC1, promotes hypoxia\/reoxygenation\u2011induced oxidative stress and inflammation in H9c2 cells by NLRP3 inflammasome activation. 27, 59. https:\/\/doi.org\/10.3892\/etm.2023.12347.","DOI":"10.3892\/etm.2023.12347"},{"key":"10.1016\/j.phymed.2024.156260_bib0016","doi-asserted-by":"crossref","unstructured":"Jiang, L., Yin, X., Chen, Y.H., Chen, Y., Jiang, W., Zheng, H., Huang, F.Q., Liu, B., Zhou, W., Qi, L.W., Li, J., 2021. Proteomic analysis reveals ginsenoside Rb1 attenuates myocardial ischemia\/reperfusion injury through inhibiting ROS production from mitochondrial complex I. 11, 1703\u20131720. https:\/\/doi.org\/10.7150\/thno.43895.","DOI":"10.7150\/thno.43895"},{"key":"10.1016\/j.phymed.2024.156260_bib0017","doi-asserted-by":"crossref","unstructured":"Liu, C.S., Chen, N.H., Zhang, J.T., 2007. Protection of PC12 cells from hydrogen peroxide-induced cytotoxicity by salvianolic acid B, a new compound isolated from Radix Salviae miltiorrhizae. 14, 492\u2013497. https:\/\/doi.org\/10.1016\/j.phymed.2006.11.002.","DOI":"10.1016\/j.phymed.2006.11.002"},{"key":"10.1016\/j.phymed.2024.156260_bib0018","doi-asserted-by":"crossref","unstructured":"Lu, J., Zhang, H., Chen, X., Zou, Y., Li, J., Wang, L., Wu, M., Zang, J., Yu, Y., Zhuang, W., Xia, Q., Wang, J., 2017. A small molecule activator of SIRT3 promotes deacetylation and activation of manganese superoxide dismutase. 112, 287\u2013297. https:\/\/doi.org\/10.1016\/j.freeradbiomed.2017.07.012.","DOI":"10.1016\/j.freeradbiomed.2017.07.012"},{"key":"10.1016\/j.phymed.2024.156260_bib0019","doi-asserted-by":"crossref","unstructured":"Luan, F., Rao, Z., Peng, L., Lei, Z., Zeng, J., Peng, X., Yang, R., Liu, R., Zeng, N., 2022. Cinnamic acid preserves against myocardial ischemia\/reperfusion injury via suppression of NLRP3\/Caspase-1\/GSDMD signaling pathway. 100, 154047. https:\/\/doi.org\/10.1016\/j.phymed.2022.154047.","DOI":"10.1016\/j.phymed.2022.154047"},{"key":"10.1016\/j.phymed.2024.156260_bib0020","doi-asserted-by":"crossref","unstructured":"Maroni, L., Agostinelli, L., Saccomanno, S., Pinto, C., Giordano, D.M., Rychlicki, C., De Minicis, S., Trozzi, L., Banales, J.M., Melum, E., Karlsen, T.H., Benedetti, A., Baroni, G.S., Marzioni, M., 2017. Nlrp3 activation induces Il-18 synthesis and affects the epithelial barrier function in reactive cholangiocytes. 187, 366\u2013376. https:\/\/doi.org\/10.1016\/j.ajpath.2016.10.010.","DOI":"10.1016\/j.ajpath.2016.10.010"},{"key":"10.1016\/j.phymed.2024.156260_bib0021","doi-asserted-by":"crossref","unstructured":"Okoye, C.N., Koren, S.A., Wojtovich, A.P., 2023. Mitochondrial complex I ROS production and redox signaling in hypoxia. 67, 102926. https:\/\/doi.org\/10.1016\/j.redox.2023.102926.","DOI":"10.1016\/j.redox.2023.102926"},{"key":"10.1016\/j.phymed.2024.156260_bib0022","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2020.153238","article-title":"Inhibitory effects of phytochemicals on NLRP3 inflammasome activation: A review","volume":"75","author":"Olcum","year":"2020","journal-title":"Phytomedicine"},{"key":"10.1016\/j.phymed.2024.156260_bib0023","doi-asserted-by":"crossref","unstructured":"Onyango, P., Celic, I., McCaffery, J.M., Boeke, J.D., Feinberg, A.P., 2002. SIRT3, a human SIR2 homologue, is an NAD-dependent deacetylase localized to mitochondria. 99, 13653\u201313658. https:\/\/doi.org\/10.1073\/pnas.222538099.","DOI":"10.1073\/pnas.222538099"},{"key":"10.1016\/j.phymed.2024.156260_bib0024","doi-asserted-by":"crossref","unstructured":"Shafique, E., Torina, A., Reichert, K., Colantuono, B., Nur, N., Zeeshan, K., Ravichandran, V., Liu, Y., Feng, J., Zeeshan, K., Benjamin, L.E., Irani, K., Harrington, E.O., Sellke, F.W., Abid, M.R., 2017. Mitochondrial redox plays a critical role in the paradoxical effects of NAPDH oxidase-derived ROS on coronary endothelium. 113, 234\u2013246. https:\/\/doi.org\/10.1093\/cvr\/cvw249.","DOI":"10.1093\/cvr\/cvw249"},{"key":"10.1016\/j.phymed.2024.156260_bib0025","doi-asserted-by":"crossref","unstructured":"Srinivas, U.S., Tan, B.W.Q., Vellayappan, B.A., Jeyasekharan, A.D., 2019. ROS and the DNA damage response in cancer. 25, 101084. https:\/\/doi.org\/10.1016\/j.redox.2018.101084.","DOI":"10.1016\/j.redox.2018.101084"},{"key":"10.1016\/j.phymed.2024.156260_bib0026","doi-asserted-by":"crossref","unstructured":"Teixeira, R.B., Pfeiffer, M., Zhang, P., Shafique, E., Rayta, B., Karbasiafshar, C., Ahsan, N., Sellke, F.W., Abid, M.R., 2023. Reduction in mitochondrial ROS improves oxidative phosphorylation and provides resilience to coronary endothelium in non-reperfused myocardial infarction. 118, 3. https:\/\/doi.org\/10.1007\/s00395-022-00976-x.","DOI":"10.1007\/s00395-022-00976-x"},{"key":"10.1016\/j.phymed.2024.156260_bib0027","doi-asserted-by":"crossref","unstructured":"Toldo, S., Abbate, A., 2018. The NLRP3 inflammasome in acute myocardial infarction. 15, 203\u2013214. https:\/\/doi.org\/10.1038\/nrcardio.2017.161.","DOI":"10.1038\/nrcardio.2017.161"},{"key":"10.1016\/j.phymed.2024.156260_bib0028","doi-asserted-by":"crossref","unstructured":"Wang, M., Ding, Y., Hu, Y., Li, Z., Luo, W., Liu, P., Li, Z., 2023. SIRT3 improved peroxisomes-mitochondria interplay and prevented cardiac hypertrophy via preserving PEX5 expression. 62, 102652. https:\/\/doi.org\/10.1016\/j.redox.2023.102652.","DOI":"10.1016\/j.redox.2023.102652"},{"key":"10.1016\/j.phymed.2024.156260_bib0029","doi-asserted-by":"crossref","unstructured":"Wang, T., Cao, Y., Zheng, Q., Tu, J., Zhou, W., He, J., Zhong, J., Chen, Y., Wang, J., Cai, R., Zuo, Y., Wei, B., Fan, Q., Yang, J., Wu, Y., Yi, J., Li, D., Liu, M., Wang, C., Zhou, A., Li, Y., Wu, X., Yang, W., Chin, Y.E., Chen, G., Cheng, J., 2019. SENP1-Sirt3 signaling controls mitochondrial protein acetylation and metabolism. 75, 823-834.e825. https:\/\/doi.org\/10.1016\/j.molcel.2019.06.008.","DOI":"10.1016\/j.molcel.2019.06.008"},{"key":"10.1016\/j.phymed.2024.156260_bib0030","doi-asserted-by":"crossref","unstructured":"Wang, Z., Sun, R., Wang, G., Chen, Z., Li, Y., Zhao, Y., Liu, D., Zhao, H., Zhang, F., Yao, J., Tian, X., 2020. SIRT3-mediated deacetylation of PRDX3 alleviates mitochondrial oxidative damage and apoptosis induced by intestinal ischemia\/reperfusion injury. 28, 101343. https:\/\/doi.org\/10.1016\/j.redox.2019.101343.","DOI":"10.1016\/j.redox.2019.101343"},{"key":"10.1016\/j.phymed.2024.156260_bib0031","doi-asserted-by":"crossref","unstructured":"Wei, X., Wu, Y., Pan, H., Zhang, Q., He, K., Xia, G., Xia, H., Lin, S., Shang, H.C., 2022a. Proteomics revealed that mitochondrial function contributed to the protective effect of Herba Siegesbeckiae against cardiac ischemia\/reperfusion injury. 9, 895797. https:\/\/doi.org\/10.3389\/fcvm.2022.895797.","DOI":"10.3389\/fcvm.2022.895797"},{"key":"10.1016\/j.phymed.2024.156260_bib0032","doi-asserted-by":"crossref","unstructured":"Wei, X., Zhang, B., Wei, F., Ding, M., Luo, Z., Han, X., Tan, X., 2022b. Gegen Qinlian pills alleviate carrageenan-induced thrombosis in mice model by regulating the HMGB1\/NF-kappaB\/NLRP3 signaling. 100, 154083. https:\/\/doi.org\/10.1016\/j.phymed.2022.154083.","DOI":"10.1016\/j.phymed.2022.154083"},{"key":"10.1016\/j.phymed.2024.156260_bib0033","unstructured":"Wu, X.F., Wei, X.H., Wu, Y.Z., Xia, G.Y., Xia, H., Wang, L.Y., Shang, H.C., Lin, S., 2022. Progress of target determination and mechanism of bioactive components of traditional Chinese medicine. 47, 4565\u20134573. https:\/\/doi.org\/10.19540\/j.cnki.cjcmm.20220330.201."},{"key":"10.1016\/j.phymed.2024.156260_bib0034","doi-asserted-by":"crossref","unstructured":"Xia, B., Tong, Y., Xia, C., Chen, C., Shan, X., 2020. \u03b1-Cyperone confers antidepressant-like effects in mice via neuroplasticity enhancement by SIRT3\/ROS mediated NLRP3 inflammasome deactivation. 11, 577062. https:\/\/doi.org\/10.3389\/fphar.2020.577062.","DOI":"10.3389\/fphar.2020.577062"},{"key":"10.1016\/j.phymed.2024.156260_bib0035","doi-asserted-by":"crossref","unstructured":"Xu, L.J., Chen, R.C., Ma, X.Y., Zhu, Y., Sun, G.B., Sun, X.B., 2020. Scutellarin protects against myocardial ischemia-reperfusion injury by suppressing NLRP3 inflammasome activation. 68, 153169. https:\/\/doi.org\/10.1016\/j.phymed.2020.153169.","DOI":"10.1016\/j.phymed.2020.153169"},{"key":"10.1016\/j.phymed.2024.156260_bib0036","doi-asserted-by":"crossref","unstructured":"Xu, X., Mao, C., Zhang, C., Zhang, M., Gong, J., Wang, X., 2023. Salvianolic acid B inhibits ferroptosis and apoptosis during myocardial ischemia\/reperfusion injury via decreasing the ubiquitin-proteasome degradation of GPX4 and the ROS-JNK\/MAPK pathways. 28. https:\/\/doi.org\/10.3390\/molecules28104117.","DOI":"10.3390\/molecules28104117"},{"key":"10.1016\/j.phymed.2024.156260_bib0037","doi-asserted-by":"crossref","unstructured":"Zhang, J., Xiang, H., Liu, J., Chen, Y., He, R.R., Liu, B., 2020. Mitochondrial Sirtuin 3: new emerging biological function and therapeutic target. 10, 8315\u20138342. https:\/\/doi.org\/10.7150\/thno.45922.","DOI":"10.7150\/thno.45922"},{"key":"10.1016\/j.phymed.2024.156260_bib0038","doi-asserted-by":"crossref","unstructured":"Zhang, J., Zhao, Y., Wang, S., Li, G., Xu, K., 2022. CREBH alleviates mitochondrial oxidative stress through SIRT3 mediating deacetylation of MnSOD and suppression of Nlrp3 inflammasome in NASH. 190, 28\u201341. https:\/\/doi.org\/10.1016\/j.freeradbiomed.2022.07.018.","DOI":"10.1016\/j.freeradbiomed.2022.07.018"},{"key":"10.1016\/j.phymed.2024.156260_bib0039","doi-asserted-by":"crossref","unstructured":"Zhao, J., Wang, G., Han, K., Wang, Y., Wang, L., Gao, J., Zhao, S., Wang, G., Chen, S., Luo, A., Wu, J., Wang, G., 2022. Mitochondrial PKM2 deacetylation by procyanidin B2-induced SIRT3 upregulation alleviates lung ischemia\/reperfusion injury. 13, 594. https:\/\/doi.org\/10.1038\/s41419-022-05051-w.","DOI":"10.1038\/s41419-022-05051-w"},{"key":"10.1016\/j.phymed.2024.156260_bib0040","doi-asserted-by":"crossref","unstructured":"Zhao, Y., Shao, C., Zhou, H., Yu, L., Bao, Y., Mao, Q., Yang, J., Wan, H., 2023. Salvianolic acid B inhibits atherosclerosis and TNF-\u03b1-induced inflammation by regulating NF-\u03baB\/NLRP3 signaling pathway. 119, 155002. https:\/\/doi.org\/10.1016\/j.phymed.2023.155002.","DOI":"10.1016\/j.phymed.2023.155002"},{"key":"10.1016\/j.phymed.2024.156260_bib0041","doi-asserted-by":"crossref","unstructured":"Zou, X., Santa-Maria, C.A., O'Brien, J., Gius, D., Zhu, Y., 2016. Manganese superoxide dismutase acetylation and dysregulation, due to loss of SIRT3 activity, promote a luminal B-like breast carcinogenic-permissive phenotype. 25, 326\u2013336. https:\/\/doi.org\/10.1089\/ars.2016.6641.","DOI":"10.1089\/ars.2016.6641"}],"container-title":["Phytomedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0944711324009176?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0944711324009176?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,1,11]],"date-time":"2025-01-11T14:26:30Z","timestamp":1736605590000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0944711324009176"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":41,"alternative-id":["S0944711324009176"],"URL":"https:\/\/doi.org\/10.1016\/j.phymed.2024.156260","relation":{},"ISSN":["0944-7113"],"issn-type":[{"value":"0944-7113","type":"print"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Salvianolic acid B alleviated myocardial ischemia-reperfusion injury via modulating SIRT3-mediated crosstalk between mitochondrial ROS and NLRP3","name":"articletitle","label":"Article Title"},{"value":"Phytomedicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.phymed.2024.156260","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier GmbH. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"156260"}}