{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T23:07:07Z","timestamp":1788822427082,"version":"build-2803163510"},"reference-count":50,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Phytomedicine"],"published-print":{"date-parts":[[2025,6]]},"DOI":"10.1016\/j.phymed.2025.156548","type":"journal-article","created":{"date-parts":[[2025,3,13]],"date-time":"2025-03-13T15:11:19Z","timestamp":1741878679000},"page":"156548","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"special_numbering":"C","title":["TaoHeChengQi Decotion alleviate chronic renal failure via regulation of PHD2\/UCP1 and RIPK3\/AKT\/TGF-\u03b2 pathway"],"prefix":"10.1016","volume":"141","author":[{"given":"Wei","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheng","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaojing","family":"Qian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunfeng","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renze","family":"Gu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenglei","family":"Meng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dongmei","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingchuan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.phymed.2025.156548_bib0002","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1111\/jvim.15454","article-title":"The renin-angiotensin-aldosterone system and its suppression","volume":"33","author":"Ames","year":"2019","journal-title":"J. Vet. Intern. Med."},{"issue":"1","key":"10.1016\/j.phymed.2025.156548_bib0003","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1038\/s41581-021-00488-2","article-title":"Lipidomic approaches to dissect dysregulated lipid metabolism in kidney disease","volume":"18","author":"Baek","year":"2022","journal-title":"Nat. Rev. Nephrol."},{"issue":"16","key":"10.1016\/j.phymed.2025.156548_bib0004","doi-asserted-by":"crossref","DOI":"10.3390\/nu15163568","article-title":"Supplemented very low protein diet (sVLPD) in patients with advanced chronic renal failure: clinical and economic benefits","volume":"15","author":"Cecchi","year":"2023","journal-title":"Nutrients."},{"issue":"7597","key":"10.1016\/j.phymed.2025.156548_bib0005","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1038\/nature17399","article-title":"Mitochondrial ROS regulate thermogenic energy expenditure and sulfenylation of UCP1","volume":"532","author":"Chouchani","year":"2016","journal-title":"Nature"},{"issue":"7","key":"10.1016\/j.phymed.2025.156548_bib0006","doi-asserted-by":"crossref","DOI":"10.3390\/toxins12070439","article-title":"Immune dysfunction in Uremia 2020","volume":"12","author":"Cohen","year":"2020","journal-title":"Toxins. (Basel)"},{"issue":"1","key":"10.1016\/j.phymed.2025.156548_bib0007","doi-asserted-by":"crossref","first-page":"e116","DOI":"10.1097\/FJC.0000000000001148","article-title":"Catalpol alleviates Ang II-induced renal injury through NF-\u03bab pathway and TGF-\u03b21\/smads pathway","volume":"79","author":"Cong","year":"2022","journal-title":"J. Cardiovasc. Pharmacol."},{"issue":"9","key":"10.1016\/j.phymed.2025.156548_bib0008","doi-asserted-by":"crossref","first-page":"1675","DOI":"10.1038\/sj.ki.5000326","article-title":"Renal risk and renoprotection among ethnic groups with type 2 diabetic nephropathy: a post hoc analysis of RENAAL","volume":"69","author":"de Zeeuw","year":"2006","journal-title":"Kidney Int."},{"key":"10.1016\/j.phymed.2025.156548_bib0009","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2024.118404","article-title":"Exploring the anti-inflammatory and immune regulatory effects of Taohe Chengqi decoction in sepsis-induced lung injury","volume":"333","author":"Deng","year":"2024","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.phymed.2025.156548_bib0010","doi-asserted-by":"crossref","DOI":"10.1016\/j.jtemb.2024.127412","article-title":"Relationship between heavy metal concentrations and chronic kidney disease in population of Hoveyzeh cohort study: A cross-sectional study in Iran","volume":"83","author":"Drikvandi","year":"2024","journal-title":"J. Trace Elem. Med. Biol."},{"key":"10.1016\/j.phymed.2025.156548_bib0011","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2022.109429","article-title":"Neoxanthin alleviates the chronic renal failure-induced aging and fibrosis by regulating inflammatory process","volume":"114","author":"Fang","year":"2023","journal-title":"Int. Immunopharmacol."},{"issue":"1","key":"10.1016\/j.phymed.2025.156548_bib0012","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1007\/s00418-023-02237-x","article-title":"HK-2 cell response to TGF-\u03b2 highly depends on cell culture medium formulations","volume":"161","author":"Garmaa","year":"2024","journal-title":"Histochem. Cell Biol."},{"key":"10.1016\/j.phymed.2025.156548_bib0013","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2022.989995","article-title":"Tandem mass tag-based proteomics analysis reveals the multitarget mechanisms of Phyllanthus emblica against liver fibrosis","volume":"13","author":"Gong","year":"2022","journal-title":"Front. Pharmacol."},{"issue":"1","key":"10.1016\/j.phymed.2025.156548_bib0014","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.nefroe.2023.04.006","article-title":"RIPK3 and kidney disease","volume":"44","author":"Guerrero-Mauvecin","year":"2024","journal-title":"Nefrologia (Engl. Ed)"},{"issue":"3","key":"10.1016\/j.phymed.2025.156548_bib0015","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1007\/s12272-022-01375-5","article-title":"Renal tubular PAR2 promotes interstitial fibrosis by increasing inflammatory responses and EMT process","volume":"45","author":"Ha","year":"2022","journal-title":"Arch. Pharm. Res."},{"issue":"1","key":"10.1016\/j.phymed.2025.156548_bib0016","doi-asserted-by":"crossref","first-page":"78","DOI":"10.2478\/jtim-2023-0004","article-title":"Evaluation of plasma vitamin E and development of proteinuria in hypertensive patients","volume":"12","author":"He","year":"2024","journal-title":"J. Transl. Int. Med."},{"issue":"3","key":"10.1016\/j.phymed.2025.156548_bib0017","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1194\/jlr.P040501","article-title":"Altered renal lipid metabolism and renal lipid accumulation in human diabetic nephropathy","volume":"55","author":"Herman-Edelstein","year":"2014","journal-title":"J. Lipid Res."},{"issue":"1","key":"10.1016\/j.phymed.2025.156548_bib0018","doi-asserted-by":"crossref","DOI":"10.3390\/cells12010088","article-title":"Oxidative stress and mitochondrial dysfunction in chronic kidney disease","volume":"12","author":"Ho","year":"2022","journal-title":"Cells"},{"issue":"5","key":"10.1016\/j.phymed.2025.156548_bib0019","doi-asserted-by":"crossref","DOI":"10.3390\/ijms25052992","article-title":"Early pulmonary fibrosis-like changes in the setting of heat exposure: DNA damage and cell senescence","volume":"25","author":"Hou","year":"2024","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.phymed.2025.156548_bib0020","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2022.116059","article-title":"Jiawei Taohe Chengqi decoction attenuates hepatic fibrosis by preventing activation of HSCs through regulating Src\/ERK\/Smad3 signal pathway","volume":"305","author":"Huang","year":"2023","journal-title":"J. Ethnopharmacol."},{"issue":"1","key":"10.1016\/j.phymed.2025.156548_bib0021","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1186\/s12933-023-02025-w","article-title":"Klotho inhibits renal ox-LDL deposition via IGF-1R\/RAC1\/OLR1 signaling to ameliorate podocyte injury in diabetic kidney disease","volume":"22","author":"Jiang","year":"2023","journal-title":"Cardiovasc. Diabetol."},{"key":"10.1016\/j.phymed.2025.156548_bib0022","doi-asserted-by":"crossref","first-page":"3131","DOI":"10.2147\/DDDT.S310882","article-title":"Wogonin alleviates kidney tubular epithelial injury in diabetic nephropathy by inhibiting PI3K\/akt\/NF-\u03bab signaling pathways","volume":"15","author":"Lei","year":"2021","journal-title":"Drug Des. Devel. Ther."},{"key":"10.1016\/j.phymed.2025.156548_bib0023","doi-asserted-by":"crossref","DOI":"10.1016\/j.molmet.2023.101747","article-title":"Proline hydroxylase 2 (PHD2) promotes brown adipose thermogenesis by enhancing the hydroxylation of UCP1","volume":"73","author":"Li","year":"2023","journal-title":"Mol. Metab."},{"issue":"3","key":"10.1016\/j.phymed.2025.156548_bib0024","doi-asserted-by":"crossref","first-page":"294","DOI":"10.2478\/jtim-2023-0105","article-title":"FOSL2 participates in renal fibrosis via SGK1-mediated epithelial-mesenchymal transition of proximal tubular epithelial cells","volume":"11","author":"Liu","year":"2023","journal-title":"J. Transl. Int. Med."},{"key":"10.1016\/j.phymed.2025.156548_bib0025","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2024.155597","article-title":"TaoHe ChengQi decoction ameliorates sepsis-induced cardiac dysfunction through anti-ferroptosis via the Nrf2 pathway","volume":"129","author":"Lu","year":"2024","journal-title":"Phytomedicine"},{"key":"10.1016\/j.phymed.2025.156548_bib0026","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2023.154983","article-title":"Biancaea decapetala (Roth) O.Deg. Extract exerts an anti-inflammatory effect by regulating the TNF\/Akt\/NF-\u03bab pathway","volume":"119","author":"Meng","year":"2023","journal-title":"Phytomedicine"},{"issue":"1","key":"10.1016\/j.phymed.2025.156548_bib0027","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1080\/0886022X.2022.2079528","article-title":"Pro- and anti-fibrotic effects of vascular endothelial growth factor in chronic kidney diseases","volume":"44","author":"Miao","year":"2022","journal-title":"Ren. Fail."},{"issue":"1","key":"10.1016\/j.phymed.2025.156548_bib0028","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.cmet.2021.11.003","article-title":"Cysteine 253 of UCP1 regulates energy expenditure and sex-dependent adipose tissue inflammation","volume":"34","author":"Mills","year":"2022","journal-title":"Cell Metab."},{"issue":"1","key":"10.1016\/j.phymed.2025.156548_bib0029","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.cveq.2021.11.003","article-title":"Chronic renal failure-causes, clinical findings, treatments and prognosis","volume":"38","author":"Olsen","year":"2022","journal-title":"Vet. Clin. North Am. Equine Pract."},{"issue":"4","key":"10.1016\/j.phymed.2025.156548_bib0030","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1016\/S0889-8537(05)70196-6","article-title":"Physiologic acid-base and electrolyte changes in acute and chronic renal failure patients","volume":"18","author":"Prough","year":"2000","journal-title":"Anesthesiol. Clin. North Am."},{"issue":"3","key":"10.1016\/j.phymed.2025.156548_bib0031","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1681\/ASN.2019050523","article-title":"Inhibition of endothelial PHD2 suppresses post-ischemic kidney inflammation through hypoxia-inducible Factor-1","volume":"31","author":"Rajendran","year":"2020","journal-title":"J. Am. Soc. Nephrol."},{"issue":"8","key":"10.1016\/j.phymed.2025.156548_bib0032","article-title":"CCN2 Activates RIPK3, NLRP3 inflammasome, and NRF2\/oxidative pathways linked to","volume":"12","author":"Rayego-Mateos","year":"2023","journal-title":"Kidney Inflammation. Antioxidants (Basel)"},{"key":"10.1016\/j.phymed.2025.156548_bib0033","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2022.978337","article-title":"Lactacystin-induced kidney fibrosis: protection by melatonin and captopril","volume":"13","author":"Repova","year":"2022","journal-title":"Front. Pharmacol."},{"issue":"11","key":"10.1016\/j.phymed.2025.156548_bib0034","doi-asserted-by":"crossref","DOI":"10.3390\/toxins14110802","article-title":"Inflammation and oxidative stress in snakebite envenomation: A brief descriptive review and clinical implications","volume":"14","author":"Resiere","year":"2022","journal-title":"Toxins. (Basel)"},{"issue":"3","key":"10.1016\/j.phymed.2025.156548_bib0035","doi-asserted-by":"crossref","DOI":"10.3390\/ijms24032988","article-title":"Chronic kidney disease as a comorbidity in heart failure","volume":"24","author":"Szlagor","year":"2023","journal-title":"Int. J. Mol. Sci."},{"issue":"1","key":"10.1016\/j.phymed.2025.156548_bib0036","doi-asserted-by":"crossref","first-page":"6538","DOI":"10.1080\/21655979.2021.1973877","article-title":"Quercetin alleviates chronic renal failure by targeting the PI3k\/Akt pathway","volume":"12","author":"Tu","year":"2021","journal-title":"Bioengineered."},{"issue":"12","key":"10.1016\/j.phymed.2025.156548_bib0037","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.1007\/s00108-021-01199-3","article-title":"[What is evidence-based in the treatment of autosomal dominant polycystic kidney disease?]","volume":"62","author":"Wulfmeyer","year":"2021","journal-title":"Internist (Berl)"},{"key":"10.1016\/j.phymed.2025.156548_bib0038","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2020.153284","article-title":"Characterization of spirostanol glycosides and furostanol glycosides from anemarrhenae rhizoma as dual targeted inhibitors of 5-lipoxygenase and cyclooxygenase-2 by employing a combination of affinity ultrafiltration and HPLC\/MS","volume":"77","author":"Xie","year":"2020","journal-title":"Phytomedicine"},{"issue":"1","key":"10.1016\/j.phymed.2025.156548_bib0039","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1111\/nyas.15173","article-title":"NAcM-OPT protects keratinocytes from H(2)O(2)-induced cell damage by promoting autophagy","volume":"1537","author":"Xiong","year":"2024","journal-title":"Ann. N. Y. Acad. Sci."},{"issue":"1","key":"10.1016\/j.phymed.2025.156548_bib0040","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1186\/s12967-023-04376-0","article-title":"UCP1 alleviates renal interstitial fibrosis progression through oxidative stress pathway mediated by SIRT3 protein stability","volume":"21","author":"Xiong","year":"2023","journal-title":"J. Transl. Med."},{"issue":"10","key":"10.1016\/j.phymed.2025.156548_bib0041","doi-asserted-by":"crossref","first-page":"4637","DOI":"10.7150\/thno.56082","article-title":"Relieving lipid accumulation through UCP1 suppresses the progression of acute kidney injury by promoting the AMPK\/ULK1\/autophagy pathway","volume":"11","author":"Xiong","year":"2021","journal-title":"Theranostics."},{"issue":"1","key":"10.1016\/j.phymed.2025.156548_bib0042","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1097\/HJH.0000000000002605","article-title":"Effects of exercise training on renal interstitial fibrosis and renin-angiotensin system in rats with chronic renal failure","volume":"39","author":"Yamakoshi","year":"2021","journal-title":"J. Hypertens."},{"key":"10.1016\/j.phymed.2025.156548_bib0043","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2023.155311","article-title":"Jolkinolide B ameliorates rheumatoid arthritis by regulating the JAK2\/STAT3 signaling pathway","volume":"124","author":"Yan","year":"2024","journal-title":"Phytomedicine"},{"issue":"3","key":"10.1016\/j.phymed.2025.156548_bib0044","doi-asserted-by":"crossref","first-page":"265","DOI":"10.2478\/jtim-2021-0051","article-title":"Protective role of autophagy in triptolide-induced apoptosis of TM3 Leydig cells","volume":"11","author":"Ye","year":"2023","journal-title":"J. Transl. Int. Med."},{"issue":"35","key":"10.1016\/j.phymed.2025.156548_bib0045","doi-asserted-by":"crossref","first-page":"31928","DOI":"10.1021\/acsomega.3c03679","article-title":"Eremophila purpurascens: anti-oxidant, anti-hyperglycemic, and hepatoprotective potential of its polyphenolic rich leaf extract and its LC-ESI-MS\/MS chemical characterization and standardization","volume":"8","author":"Youssef","year":"2023","journal-title":"ACS. Omega"},{"issue":"1","key":"10.1016\/j.phymed.2025.156548_bib0046","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1186\/s13020-022-00671-y","article-title":"Nitidine chloride induces caspase 3\/GSDME-dependent pyroptosis by inhibting PI3K\/akt pathway in lung cancer","volume":"17","author":"Yu","year":"2022","journal-title":"Chin. Med."},{"key":"10.1016\/j.phymed.2025.156548_bib0047","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2023.155315","article-title":"Taohe Chengqi decoction alleviated metabolic-associated fatty liver disease by boosting branched chain amino acids catabolism in the skeletal muscles of type 2 diabetes mellitus","volume":"126","author":"Yuan","year":"2024","journal-title":"Phytomedicine"},{"issue":"2","key":"10.1016\/j.phymed.2025.156548_bib0048","doi-asserted-by":"crossref","first-page":"157","DOI":"10.2478\/jtim-2022-0049","article-title":"Irbesartan ameliorates diabetic kidney injury in db\/db mice by restoring circadian rhythm and cell cycle","volume":"12","author":"Zhao","year":"2024","journal-title":"J. Transl. Int. Med."},{"key":"10.1016\/j.phymed.2025.156548_bib0049","doi-asserted-by":"crossref","first-page":"425","DOI":"10.3389\/fphar.2020.00425","article-title":"Deciphering the pharmacological mechanisms of Taohe-Chengqi decoction extract against renal fibrosis through integrating network pharmacology and experimental validation In vitro and In vivo","volume":"11","author":"Zhou","year":"2020","journal-title":"Front. Pharmacol."},{"issue":"4","key":"10.1016\/j.phymed.2025.156548_bib0050","doi-asserted-by":"crossref","first-page":"1583","DOI":"10.7150\/thno.92848","article-title":"MAGL protects against renal fibrosis through inhibiting tubular cell lipotoxicity","volume":"14","author":"Zhou","year":"2024","journal-title":"Theranostics."},{"issue":"5","key":"10.1016\/j.phymed.2025.156548_bib0051","doi-asserted-by":"crossref","first-page":"611","DOI":"10.2337\/db22-0680","article-title":"Metrnl alleviates lipid accumulation by modulating mitochondrial homeostasis in diabetic nephropathy","volume":"72","author":"Zhou","year":"2023","journal-title":"Diabetes"}],"container-title":["Phytomedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0944711325001886?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0944711325001886?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T08:46:55Z","timestamp":1762332415000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0944711325001886"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":50,"alternative-id":["S0944711325001886"],"URL":"https:\/\/doi.org\/10.1016\/j.phymed.2025.156548","relation":{},"ISSN":["0944-7113"],"issn-type":[{"value":"0944-7113","type":"print"}],"subject":[],"published":{"date-parts":[[2025,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"TaoHeChengQi Decotion alleviate chronic renal failure via regulation of PHD2\/UCP1 and RIPK3\/AKT\/TGF-\u03b2 pathway","name":"articletitle","label":"Article Title"},{"value":"Phytomedicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.phymed.2025.156548","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Published by Elsevier GmbH.","name":"copyright","label":"Copyright"}],"article-number":"156548"}}