{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T02:27:21Z","timestamp":1791685641144,"version":"4.3.4"},"reference-count":55,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100007846","name":"Yunnan Provincial Department of Education","doi-asserted-by":"publisher","award":["2024Y029"],"award-info":[{"award-number":["2024Y029"]}],"id":[{"id":"10.13039\/501100007846","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100018531","name":"Major Science and Technology Projects in Yunnan Province","doi-asserted-by":"publisher","award":["202301AT070109"],"award-info":[{"award-number":["202301AT070109"]}],"id":[{"id":"10.13039\/501100018531","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100018531","name":"Major Science and Technology Projects in Yunnan Province","doi-asserted-by":"publisher","award":["202501AS070056"],"award-info":[{"award-number":["202501AS070056"]}],"id":[{"id":"10.13039\/501100018531","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100018531","name":"Major Science and Technology Projects in Yunnan Province","doi-asserted-by":"publisher","award":["202301BF070001-017"],"award-info":[{"award-number":["202301BF070001-017"]}],"id":[{"id":"10.13039\/501100018531","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["U24A20805"],"award-info":[{"award-number":["U24A20805"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82301535"],"award-info":[{"award-number":["82301535"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007839","name":"Yunnan University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007839","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Phytomedicine"],"published-print":{"date-parts":[[2025,7]]},"DOI":"10.1016\/j.phymed.2025.156866","type":"journal-article","created":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T19:34:46Z","timestamp":1747251286000},"page":"156866","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"special_numbering":"C","title":["Evodiamine inhibits NLRP3 inflammasome-mediated microglial pyroptosis and promotes remyelination via SLC2A4-regulated autophagy"],"prefix":"10.1016","volume":"143","author":[{"given":"Yunjie","family":"Zhao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xingzong","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Faling","family":"Shao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lin","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weilie","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chengyang","family":"Gu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunqian","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yue","family":"Jia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lili","family":"Dai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongliang","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7563-0520","authenticated-orcid":false,"given":"Hongkun","family":"Bao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.phymed.2025.156866_bib0001","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1080\/15548627.2023.2259281","article-title":"The beneficial role of autophagy in multiple sclerosis: yes or no?","volume":"20","author":"AL-KURAISHY","year":"2023","journal-title":"Autophagy."},{"key":"10.1016\/j.phymed.2025.156866_bib0002","doi-asserted-by":"crossref","first-page":"1756","DOI":"10.1152\/jn.00224.2021","article-title":"Temporal and spatial evolution of various functional neurons during demyelination induced by cuprizone","volume":"126","author":"AN","year":"2021","journal-title":"J. Neurophysiol."},{"key":"10.1016\/j.phymed.2025.156866_bib0003","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1038\/nrmicro2070","article-title":"Pyroptosis: host cell death and inflammation","volume":"7","author":"BERGSBAKEN","year":"2009","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.phymed.2025.156866_bib0004","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1038\/nri.2016.100","article-title":"Crosstalk between autophagy and inflammatory signalling pathways: balancing defence and homeostasis","volume":"16","author":"CADWELL","year":"2016","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.phymed.2025.156866_bib0005","first-page":"7","article-title":"Functional inflammatory profiles distinguish myelin-reactive T cells from patients with multiple sclerosis","author":"CAO","year":"2015","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.phymed.2025.156866_bib0006","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.1093\/abbs\/gmz098","article-title":"Interaction between autophagy and the NLRP3 inflammasome","volume":"51","author":"CAO","year":"2019","journal-title":"Acta Biochim. Biophys. Sin. (Shanghai)"},{"key":"10.1016\/j.phymed.2025.156866_bib0007","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jneuroim.2018.02.015","article-title":"The roles of macrophages and microglia in multiple sclerosis and experimental autoimmune encephalomyelitis","volume":"318","author":"CHU","year":"2018","journal-title":"J. Neuroimmunol."},{"key":"10.1016\/j.phymed.2025.156866_bib0008","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1111\/j.1476-5381.2011.01302.x","article-title":"Experimental autoimmune encephalomyelitis (EAE) as a model for multiple sclerosis (MS)","volume":"164","author":"CONSTANTINESCU","year":"2012","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.phymed.2025.156866_bib0009","first-page":"15","article-title":"Focus on the role of the NLRP3 inflammasome in multiple sclerosis: pathogenesis, diagnosis, and therapeutics","author":"CUI","year":"2022","journal-title":"Front. Mol. Neurosci."},{"key":"10.1016\/j.phymed.2025.156866_bib0010","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/j.coi.2010.02.013","article-title":"Inflammatory cytokines as a third signal for T cell activation","volume":"22","author":"CURTSINGER","year":"2010","journal-title":"Curr. Opin. Immunol."},{"key":"10.1016\/j.phymed.2025.156866_bib0011","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1038\/nri3871","article-title":"Immunopathology of multiple sclerosis","volume":"15","author":"DENDROU","year":"2015","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.phymed.2025.156866_bib0012","first-page":"15","article-title":"Traditional Chinese medicine for anti-Alzheimer\u2019s disease: berberine and evodiamine from Evodia rutaecarpa","author":"FANG","year":"2020","journal-title":"Chin. Med."},{"key":"10.1016\/j.phymed.2025.156866_bib0013","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1038\/nrn.2017.136","article-title":"Regenerating CNS myelin \u2014 From mechanisms to experimental medicines","volume":"18","author":"FRANKLIN","year":"2017","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.phymed.2025.156866_bib0014","first-page":"22","article-title":"Microglia: the missing link to decipher and therapeutically control MS progression?","author":"GELADARIS","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.phymed.2025.156866_bib0015","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2021\/9925059","article-title":"Autophagy regulation on pyroptosis: mechanism and medical implication in sepsis","volume":"2021","author":"GUO","year":"2021","journal-title":"Mediators. Inflamm."},{"key":"10.1016\/j.phymed.2025.156866_bib0016","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.molimm.2017.02.013","article-title":"Autophagy and inflammasomes","volume":"86","author":"HARRIS","year":"2017","journal-title":"Mol. Immunol."},{"key":"10.1016\/j.phymed.2025.156866_bib0017","doi-asserted-by":"crossref","first-page":"2218","DOI":"10.1523\/JNEUROSCI.20-06-02218.2000","article-title":"Proliferation and differentiation of progenitor cells throughout the intact adult rat spinal cord","volume":"20","author":"HORNER","year":"2000","journal-title":"J. Neurosci."},{"key":"10.1016\/j.phymed.2025.156866_bib0018","first-page":"20","article-title":"Huc-MSCs-derived exosomes attenuate inflammatory pain by regulating microglia pyroptosis and autophagy via the miR-146a-5p\/TRAF6 axis","author":"HUA","year":"2022","journal-title":"J. Nanobiotechnology."},{"key":"10.1016\/j.phymed.2025.156866_bib0019","series-title":"Pharmaceutics.","first-page":"12","article-title":"Monocarboxylate transporter 6-mediated interactions with prostaglandin F2\u03b1: in Vitro and In vivo evidence utilizing a knockout mouse model","author":"JONES","year":"2020"},{"key":"10.1016\/j.phymed.2025.156866_bib0020","doi-asserted-by":"crossref","first-page":"E974","DOI":"10.1152\/ajpendo.00407.2001","article-title":"Nomenclature of the GLUT\/SLC2A family of sugar\/polyol transport facilitators","volume":"282","author":"JOOST","year":"2002","journal-title":"Am. J. Physiol. -Endocrinol. Metab."},{"key":"10.1016\/j.phymed.2025.156866_bib0021","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1080\/09687680110090456","article-title":"The extended GLUT-family of sugar\/polyol transport facilitators: nomenclature, sequence characteristics, and potential function of its novel members","volume":"18","author":"JOOST","year":"2009","journal-title":"Mol. Membr. Biol."},{"key":"10.1016\/j.phymed.2025.156866_bib0022","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1038\/s41577-023-00907-4","article-title":"Microglia regulation of central nervous system myelin health and regeneration","volume":"24","author":"KENT","year":"2023","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.phymed.2025.156866_bib0023","doi-asserted-by":"crossref","first-page":"4062","DOI":"10.1080\/15548627.2021.1900498","article-title":"Combination of autophagy and NFE2L2\/NRF2 activation as a treatment approach for neuropathic pain","volume":"17","author":"LI","year":"2021","journal-title":"Autophagy."},{"key":"10.1016\/j.phymed.2025.156866_bib0024","first-page":"22","article-title":"Research progress on evodiamine, a bioactive alkaloid of Evodiae fructus: focus on its anti\u2011cancer activity and bioavailability (Review)","author":"LUO","year":"2021","journal-title":"Exp. Ther. Med."},{"key":"10.1016\/j.phymed.2025.156866_bib0025","first-page":"115","article-title":"Caspase-1 inhibition prevents glial inflammasome activation and pyroptosis in models of multiple sclerosis","author":"MCKENZIE","year":"2018","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.phymed.2025.156866_bib0026","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1530\/rep.1.00203","article-title":"Two insulin-responsive glucose transporter isoforms and the insulin receptor are developmentally expressed in rabbit preimplantation embryos","volume":"128","author":"NAVARRETE SANTOS","year":"2004","journal-title":"Reproduction."},{"key":"10.1016\/j.phymed.2025.156866_bib0027","doi-asserted-by":"crossref","first-page":"1180","DOI":"10.1172\/JCI58649","article-title":"Multiple sclerosis","volume":"122","author":"NYLANDER","year":"2012","journal-title":"J. Clin. Investig."},{"key":"10.1016\/j.phymed.2025.156866_bib0028","doi-asserted-by":"crossref","first-page":"1596","DOI":"10.1161\/01.ATV.0000170137.41079.ab","article-title":"GLUT4 Facilitative glucose transporter specifically and differentially contributes to agonist-induced vascular reactivity in mouse aorta","volume":"25","author":"PARK","year":"2005","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.phymed.2025.156866_bib0029","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1111\/ene.15593","article-title":"Diagnosis and treatment of progressive multiple sclerosis: a position paper","volume":"30","author":"POZZILLI","year":"2022","journal-title":"Eur. J. Neurol."},{"key":"10.1016\/j.phymed.2025.156866_bib0030","article-title":"The experimental autoimmune encephalomyelitis (EAE) model of MS","author":"ROBINSON","year":"2014","journal-title":"Mult. Scler. Relat. Disord."},{"key":"10.1016\/j.phymed.2025.156866_bib0031","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1111\/cns.12349","article-title":"Activating cannabinoid receptor 2 alleviates pathogenesis of experimental autoimmune encephalomyelitis via activation of autophagy and inhibiting NLRP3 inflammasome","volume":"20","author":"SHAO","year":"2014","journal-title":"CNS. Neurosci. Ther."},{"key":"10.1016\/j.phymed.2025.156866_bib0032","doi-asserted-by":"crossref","first-page":"2234","DOI":"10.1016\/j.cell.2022.05.020","article-title":"Bone marrow hematopoiesis drives multiple sclerosis progression","volume":"185","author":"SHI","year":"2022","journal-title":"Cell"},{"key":"10.1016\/j.phymed.2025.156866_bib0033","first-page":"13","article-title":"Th17 cells and inflammation in neurological disorders: possible mechanisms of action","author":"SHI","year":"2022","journal-title":"Front. Immunol."},{"key":"10.1016\/j.phymed.2025.156866_bib0034","series-title":"Antioxidants","first-page":"9","article-title":"ROS generation in microglia: understanding oxidative stress and inflammation in neurodegenerative disease","author":"SIMPSON","year":"2020"},{"key":"10.1016\/j.phymed.2025.156866_bib0035","doi-asserted-by":"crossref","first-page":"188","DOI":"10.2119\/molmed.2017.00077","article-title":"Inflammasome and autophagy regulation: a two-way street","volume":"23","author":"SUN","year":"2017","journal-title":"Mol. Med."},{"key":"10.1016\/j.phymed.2025.156866_bib0036","first-page":"13","article-title":"HMGB1 released from GSDME-mediated pyroptotic epithelial cells participates in the tumorigenesis of colitis-associated colorectal cancer through the ERK1\/2 pathway","author":"TAN","year":"2020","journal-title":"J. Hematol. Oncol."},{"key":"10.1016\/j.phymed.2025.156866_bib0037","first-page":"10","article-title":"Induction of microglia activation after infection with the non-neurotropic A\/CA\/04\/2009 H1N1 influenza virus","author":"TANSEY","year":"2015","journal-title":"PLoS. One"},{"key":"10.1016\/j.phymed.2025.156866_bib0038","first-page":"47","article-title":"Endothelin antagonism: effects of FP receptor agonists prostaglandin F2\u03b1and fluprostenol on trabecular meshwork contractility","author":"THIEME","year":"2006","journal-title":"Investig. Opthalmol. Vis. Sci."},{"key":"10.1016\/j.phymed.2025.156866_bib0039","first-page":"208","article-title":"Expression of the insulin-responsive glucose transporter isoform 4 in blastocysts of C57\/BL6 mice","author":"TONACK","year":"2004","journal-title":"Anat. Embryol."},{"key":"10.1016\/j.phymed.2025.156866_bib0040","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1016\/j.aanat.2009.06.002","article-title":"Expression of glucose transporter isoforms and the insulin receptor during hamster preimplantation embryo development","volume":"191","author":"TONACK","year":"2009","journal-title":"Ann. Anat. - Anatomischer Anzeiger"},{"key":"10.1016\/j.phymed.2025.156866_bib0041","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.brainresbull.2019.05.003","article-title":"Mild hypothermia alleviates diabetes aggravated cerebral ischemic injury via activating autophagy and inhibiting pyroptosis","volume":"150","author":"TU","year":"2019","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.phymed.2025.156866_bib0042","first-page":"69","article-title":"Pyroptosis-induced inflammation and tissue damage","author":"VASUDEVAN","year":"2023","journal-title":"Semin. Immunol."},{"key":"10.1016\/j.phymed.2025.156866_bib0043","doi-asserted-by":"crossref","first-page":"129","DOI":"10.2174\/1570159X15666170717120343","article-title":"Five decades of cuprizone, an updated model to replicate demyelinating diseases","volume":"17","author":"VEGA-RIQUER","year":"2019","journal-title":"Curr. Neuropharmacol."},{"key":"10.1016\/j.phymed.2025.156866_bib0044","first-page":"90","article-title":"Nicotinamide adenine dinucleotide treatment alleviates the symptoms of experimental autoimmune encephalomyelitis by activating autophagy and inhibiting the NLRP3 inflammasome","author":"WANG","year":"2021","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.phymed.2025.156866_bib0045","first-page":"9","article-title":"Induction of pyroptosis and its implications in cancer management","author":"WANG","year":"2019","journal-title":"Front. Oncol."},{"key":"10.1016\/j.phymed.2025.156866_bib0046","first-page":"220","article-title":"Forsythoside B ameliorates neuroinflammation via inhibiting NLRP3 inflammasome of glial cells in experimental autoimmune encephalomyelitis mice","author":"WANG","year":"2025","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.phymed.2025.156866_bib0047","first-page":"14","article-title":"IRAK-M suppresses the activation of microglial NLRP3 inflammasome and GSDMD-mediated pyroptosis through inhibiting IRAK1 phosphorylation during experimental autoimmune encephalomyelitis","author":"WANG","year":"2023","journal-title":"Cell Death. Dis."},{"key":"10.1016\/j.phymed.2025.156866_bib0048","first-page":"20","article-title":"Regulatory T cells alleviate myelin loss and cognitive dysfunction by regulating neuroinflammation and microglial pyroptosis via TLR4\/MyD88\/NF-\u03bab pathway in LPC-induced demyelination","author":"WANG","year":"2023","journal-title":"J. Neuroinflamm."},{"key":"10.1016\/j.phymed.2025.156866_bib0049","first-page":"22","article-title":"Multiple sclerosis and pregnancy: pathogenesis, influencing factors, and treatment options","author":"WANG","year":"2023","journal-title":"Autoimmun. Rev."},{"key":"10.1016\/j.phymed.2025.156866_bib0050","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1210\/er.2003-0011","article-title":"Regulated membrane trafficking of the insulin-responsive glucose transporter 4 in adipocytes","volume":"25","author":"WATSON","year":"2004","journal-title":"Endocr. Rev."},{"key":"10.1016\/j.phymed.2025.156866_bib0051","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1038\/s41418-018-0105-8","article-title":"lincRNA-Cox2 regulates NLRP3 inflammasome and autophagy mediated neuroinflammation","volume":"26","author":"XUE","year":"2018","journal-title":"Cell Death Different."},{"key":"10.1016\/j.phymed.2025.156866_bib0052","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/s40164-022-00263-4","article-title":"Targeting PD-1\/PD-L1 pathway in myelodysplastic syndromes and acute myeloid leukemia","author":"YANG","year":"2022","journal-title":"Exp. Hematol. Oncol."},{"key":"10.1016\/j.phymed.2025.156866_bib0053","doi-asserted-by":"crossref","first-page":"1981","DOI":"10.1007\/s00011-024-01945-x","article-title":"Cynarin inhibits microglia-induced pyroptosis and neuroinflammation via Nrf2\/ROS\/NLRP3 axis after spinal cord injury","volume":"73","author":"ZHANG","year":"2024","journal-title":"Inflamm. Res."},{"key":"10.1016\/j.phymed.2025.156866_bib0054","first-page":"23","article-title":"Paeonol regulates NLRP3 inflammasomes and pyroptosis to alleviate spinal cord injury of rat","author":"ZHAO","year":"2022","journal-title":"BMC. Neurosci."},{"key":"10.1016\/j.phymed.2025.156866_bib0055","first-page":"116","article-title":"Microglial pyroptosis in hippocampus mediates sevolfurane-induced cognitive impairment in aged mice via ROS-NLRP3 inflammasome pathway","author":"ZHOU","year":"2023","journal-title":"Int. Immunopharmacol."}],"container-title":["Phytomedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0944711325005045?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0944711325005045?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T08:53:42Z","timestamp":1762332822000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0944711325005045"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7]]},"references-count":55,"alternative-id":["S0944711325005045"],"URL":"https:\/\/doi.org\/10.1016\/j.phymed.2025.156866","relation":{},"ISSN":["0944-7113"],"issn-type":[{"value":"0944-7113","type":"print"}],"subject":[],"published":{"date-parts":[[2025,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Evodiamine inhibits NLRP3 inflammasome-mediated microglial pyroptosis and promotes remyelination via SLC2A4-regulated autophagy","name":"articletitle","label":"Article Title"},{"value":"Phytomedicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.phymed.2025.156866","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier GmbH. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"156866"}}