{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T01:47:43Z","timestamp":1793411263557,"version":"4.5.0"},"reference-count":50,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100002947","name":"Anhui Medical University","doi-asserted-by":"publisher","award":["YJS20230185"],"award-info":[{"award-number":["YJS20230185"]}],"id":[{"id":"10.13039\/501100002947","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003995","name":"Natural Science Foundation of Anhui Province","doi-asserted-by":"publisher","award":["2308085QH277"],"award-info":[{"award-number":["2308085QH277"]}],"id":[{"id":"10.13039\/501100003995","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82370776"],"award-info":[{"award-number":["82370776"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82400905"],"award-info":[{"award-number":["82400905"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Phytomedicine"],"published-print":{"date-parts":[[2025,11]]},"DOI":"10.1016\/j.phymed.2025.157210","type":"journal-article","created":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T23:04:56Z","timestamp":1756335896000},"page":"157210","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"special_numbering":"C","title":["Lycium barbarum polysaccharides alleviate experimental autoimmune prostatitis by putrescine\/TRAF\/JAK\/STAT-mediated Th17 differentiation"],"prefix":"10.1016","volume":"147","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-1569-4583","authenticated-orcid":false,"given":"Xu","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shao-Yu","family":"Yue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jia","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-3734-6767","authenticated-orcid":false,"given":"Sheng-Ao","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chao-Jie","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rong-Rong","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ling-Fan","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"An-Dong","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qing-Wei","family":"Meng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Di","family":"Niu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chao-Zhao","family":"Liang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.phymed.2025.157210_bib0001","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1002\/pros.23252","article-title":"Chronic pelvic pain development and prostate inflammation in strains of mice with different susceptibility to experimental autoimmune prostatitis","volume":"77","author":"Breser","year":"2017","journal-title":"Prostate"},{"key":"10.1016\/j.phymed.2025.157210_bib0002","doi-asserted-by":"crossref","first-page":"383","DOI":"10.2174\/1573406410666141110153858","article-title":"Practical application of antidiabetic efficacy of lycium barbarum polysaccharide in patients with type 2 diabetes","volume":"11","author":"Cai","year":"2015","journal-title":"Med. Chem."},{"key":"10.1016\/j.phymed.2025.157210_bib0003","doi-asserted-by":"crossref","first-page":"4750","DOI":"10.1182\/blood-2009-09-242768","article-title":"TRAF6 inhibits Th17 differentiation and TGF-beta-mediated suppression of IL-2","volume":"115","author":"Cejas","year":"2010","journal-title":"Blood"},{"key":"10.1016\/j.phymed.2025.157210_bib0004","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1007\/s12026-007-8014-9","article-title":"Th17 cells: a new fate for differentiating helper T cells","volume":"41","author":"Chen","year":"2008","journal-title":"Immunol. Res."},{"key":"10.1016\/j.phymed.2025.157210_bib0005","first-page":"33","article-title":"An evidence-based update on the pharmacological activities and possible molecular targets of Lycium barbarum polysaccharides","volume":"9","author":"Cheng","year":"2015","journal-title":"Drug Des. Devel. Ther."},{"key":"10.1016\/j.phymed.2025.157210_bib0006","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.aax2220","article-title":"Gut microbiota dysbiosis and altered tryptophan catabolism contribute to autoimmunity in lupus-susceptible mice","volume":"12","author":"Choi","year":"2020","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.phymed.2025.157210_bib0007","doi-asserted-by":"crossref","first-page":"j5145","DOI":"10.1136\/bmj.j5145","article-title":"The role of the gut microbiome in systemic inflammatory disease","volume":"360","author":"Clemente","year":"2018","journal-title":"BMJ"},{"key":"10.1016\/j.phymed.2025.157210_bib0008","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1038\/nri1807","article-title":"Diversification of T-helper-cell lineages: finding the family root of IL-17-producing cells","volume":"6","author":"Dong","year":"2006","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.phymed.2025.157210_bib0009","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1007\/s10571-019-00723-2","article-title":"Experimental autoimmune prostatitis induces learning-memory impairment and structural neuroplastic changes in mice","volume":"40","author":"Du","year":"2020","journal-title":"Cell. Mol. Neurobiol."},{"key":"10.1016\/j.phymed.2025.157210_bib0010","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2022.915218","article-title":"Gut microflora modulates Th17\/treg cell differentiation in experimental autoimmune prostatitis via the short-chain fatty acid propionate","volume":"13","author":"Du","year":"2022","journal-title":"Front. Immunol."},{"key":"10.1016\/j.phymed.2025.157210_bib0011","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2024.112669","article-title":"Alcohol intake exacerbates experimental autoimmune prostatitis through gut microbiota driving cholesterol biosynthesis-mediated Th17 differentiation","volume":"139","author":"Du","year":"2024","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.phymed.2025.157210_bib0012","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.eururo.2009.08.020","article-title":"EAU guidelines on chronic pelvic pain","volume":"57","author":"Fall","year":"2010","journal-title":"Eur. Urol."},{"key":"10.1016\/j.phymed.2025.157210_bib0013","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2024.1325283","article-title":"Traditional uses, phytochemistry, pharmacology, toxicity and clinical application of traditional Chinese medicine Cynoglossum amabile: a review","volume":"15","author":"Fan","year":"2024","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.phymed.2025.157210_bib0014","article-title":"Pharmacological interventions for treating chronic prostatitis\/chronic pelvic pain syndrome","volume":"10","author":"Franco","year":"2019","journal-title":"Cochrane Database Syst. Rev."},{"key":"10.1016\/j.phymed.2025.157210_bib0015","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1016\/j.ijbiomac.2020.01.251","article-title":"Arabinogalactan derived from Lycium barbarum fruit inhibits cancer cell growth via cell cycle arrest and apoptosis","volume":"149","author":"Gong","year":"2020","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.phymed.2025.157210_bib0016","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1038\/s41568-022-00473-2","article-title":"Polyamines in cancer: integrating organismal metabolism and antitumour immunity","volume":"22","author":"Holbert","year":"2022","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.phymed.2025.157210_bib0017","doi-asserted-by":"crossref","first-page":"1268","DOI":"10.1126\/science.1223490","article-title":"Interactions between the microbiota and the immune system","volume":"336","author":"Hooper","year":"2012","journal-title":"Science"},{"key":"10.1016\/j.phymed.2025.157210_bib0018","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1016\/j.cell.2006.07.035","article-title":"The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells","volume":"126","author":"Ivanov","year":"2006","journal-title":"Cell"},{"key":"10.1016\/j.phymed.2025.157210_bib0019","doi-asserted-by":"crossref","DOI":"10.1016\/j.jaut.2023.103050","article-title":"Compositional and functional aberrance of the gut microbiota in treatment-na\u00efve patients with primary Sj\u00f6gren's syndrome","volume":"141","author":"Jia","year":"2023","journal-title":"J. Autoimmun."},{"key":"10.1016\/j.phymed.2025.157210_bib0020","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1186\/s12967-023-04648-9","article-title":"Lycium barbarum glycopeptide alleviates neuroinflammation in spinal cord injury via modulating docosahexaenoic acid to inhibiting MAPKs\/NF-kB and pyroptosis pathways","volume":"21","author":"Jiang","year":"2023","journal-title":"J. Transl. Med."},{"key":"10.1016\/j.phymed.2025.157210_bib0021","doi-asserted-by":"crossref","first-page":"1540","DOI":"10.1016\/j.scib.2023.06.027","article-title":"Sinomenine ameliorates rheumatoid arthritis by modulating tryptophan metabolism and activating aryl hydrocarbon receptor via gut microbiota regulation","volume":"68","author":"Jiang","year":"2023","journal-title":"Sci. Bull. (Beijing)"},{"key":"10.1016\/j.phymed.2025.157210_bib0022","doi-asserted-by":"crossref","first-page":"566","DOI":"10.4049\/jimmunol.177.1.566","article-title":"IL-17 plays an important role in the development of experimental autoimmune encephalomyelitis","volume":"177","author":"Komiyama","year":"2006","journal-title":"J. Immunol."},{"key":"10.1016\/j.phymed.2025.157210_bib0023","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1001\/jama.282.3.236","article-title":"NIH consensus definition and classification of prostatitis","volume":"282","author":"Krieger","year":"1999","journal-title":"JAMa"},{"key":"10.1016\/j.phymed.2025.157210_bib0024","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1080\/15548627.2019.1635384","article-title":"New insights into the interplay between autophagy, gut microbiota and inflammatory responses in IBD","volume":"16","author":"Larabi","year":"2020","journal-title":"Autophagy"},{"key":"10.1016\/j.phymed.2025.157210_bib0025","doi-asserted-by":"crossref","first-page":"1787","DOI":"10.1136\/gutjnl-2012-303816","article-title":"Intestinal microbiota determines development of non-alcoholic fatty liver disease in mice","volume":"62","author":"Le Roy","year":"2013","journal-title":"Gut"},{"key":"10.1016\/j.phymed.2025.157210_bib0026","doi-asserted-by":"crossref","DOI":"10.1080\/19490976.2024.2402547","article-title":"Prebiotic inulin controls Th17 cells mediated central nervous system autoimmunity through modulating the gut microbiota and short chain fatty acids","volume":"16","author":"Li","year":"2024","journal-title":"Gut. Microbes."},{"key":"10.1016\/j.phymed.2025.157210_bib0027","article-title":"Multi-omics analysis reveals changes in the intestinal microbiome, transcriptome, and methylome in a rat model of chronic non-bacterial prostatitis: indications for the existence of the gut-prostate axis","volume":"12","author":"Liu","year":"2021","journal-title":"Front. Physiol."},{"key":"10.1016\/j.phymed.2025.157210_bib0028","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.it.2020.12.005","article-title":"Systemic immunoregulatory consequences of gut commensal translocation","volume":"42","author":"McPherson","year":"2021","journal-title":"Trends. Immunol."},{"key":"10.1016\/j.phymed.2025.157210_bib0029","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1111\/bju.15117","article-title":"Patients with chronic prostatitis\/chronic pelvic pain syndrome show T helper type 1 (Th1) and Th17 self-reactive immune responses specific to prostate and seminal antigens and diminished semen quality","volume":"126","author":"Motrich","year":"2020","journal-title":"BJu Int."},{"key":"10.1016\/j.phymed.2025.157210_bib0030","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1038\/nrurol.2014.63","article-title":"Immune mediators of chronic pelvic pain syndrome","volume":"11","author":"Murphy","year":"2014","journal-title":"Nat. Rev. Urol."},{"key":"10.1016\/j.phymed.2025.157210_bib0031","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2024.111682","article-title":"High glucose intake exacerbates experimental autoimmune prostatitis through mitochondrial reactive oxygen species-dependent TGF-\u03b2 activation-mediated Th17 differentiation","volume":"130","author":"Niu","year":"2024","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.phymed.2025.157210_bib0032","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1038\/pcan.2016.8","article-title":"Chronic prostatitis\/chronic pelvic pain syndrome: a review of evaluation and therapy","volume":"19","author":"Polackwich","year":"2016","journal-title":"Prostate Cancer Prostatic. Dis."},{"key":"10.1016\/j.phymed.2025.157210_bib0033","doi-asserted-by":"crossref","first-page":"4186","DOI":"10.1016\/j.cell.2021.06.007","article-title":"Polyamine metabolism is a central determinant of helper T cell lineage fidelity","volume":"184","author":"Puleston","year":"2021","journal-title":"Cell"},{"key":"10.1016\/j.phymed.2025.157210_bib0034","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1038\/s41391-021-00464-8","article-title":"Outcomes and clinical predictors of extracorporeal shock wave therapy in the treatment of chronic prostatitis\/chronic pelvic pain syndrome: a prospective randomized double-blind placebo-controlled clinical trial","volume":"25","author":"Sakr","year":"2022","journal-title":"Prostate Cancer Prostatic. Dis."},{"key":"10.1016\/j.phymed.2025.157210_bib0035","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/j.juro.2016.02.2959","article-title":"Analysis of gut microbiome reveals significant differences between men with chronic prostatitis\/chronic pelvic pain syndrome and controls","volume":"196","author":"Shoskes","year":"2016","journal-title":"J. Urol."},{"key":"10.1016\/j.phymed.2025.157210_bib0036","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00535-016-1242-9","article-title":"Microbiota metabolite short chain fatty acids, GPCR, and inflammatory bowel diseases","volume":"52","author":"Sun","year":"2017","journal-title":"J. Gastroenterol."},{"key":"10.1016\/j.phymed.2025.157210_bib0037","doi-asserted-by":"crossref","first-page":"1357","DOI":"10.7326\/M21-1814","article-title":"Efficacy of acupuncture for chronic prostatitis\/chronic pelvic pain syndrome: a randomized trial","volume":"174","author":"Sun","year":"2021","journal-title":"Ann. Intern. Med."},{"key":"10.1016\/j.phymed.2025.157210_bib0038","doi-asserted-by":"crossref","first-page":"4231","DOI":"10.1039\/C8FO01751D","article-title":"Lycium barbarum polysaccharides extend the mean lifespan of Drosophila melanogaster","volume":"10","author":"Tang","year":"2019","journal-title":"Food Funct."},{"key":"10.1016\/j.phymed.2025.157210_bib0039","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1038\/s41586-018-0620-2","article-title":"The human gut microbiome in early-onset type 1 diabetes from the TEDDY study","volume":"562","author":"Vatanen","year":"2018","journal-title":"Nature"},{"key":"10.1016\/j.phymed.2025.157210_bib0040","article-title":"Lycium barbarum polysaccharide alleviates dextran sodium sulfate-induced inflammatory bowel disease by regulating M1\/M2 macrophage polarization via the STAT1 and STAT6 pathways","volume":"14","author":"Wang","year":"2023","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.phymed.2025.157210_bib0041","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0049567","article-title":"The ubiquitin ligase TRAF6 negatively regulates the JAK-STAT signaling pathway by binding to STAT3 and mediating its ubiquitination","volume":"7","author":"Wei","year":"2012","journal-title":"PLoS. One"},{"key":"10.1016\/j.phymed.2025.157210_bib0042","doi-asserted-by":"crossref","first-page":"5587","DOI":"10.1038\/srep05587","article-title":"Lycium barbarum polysaccharides therapeutically improve hepatic functions in non-alcoholic steatohepatitis rats and cellular steatosis model","volume":"4","author":"Xiao","year":"2014","journal-title":"Sci. Rep."},{"key":"10.1016\/j.phymed.2025.157210_bib0043","doi-asserted-by":"crossref","first-page":"798","DOI":"10.1038\/nrc2734","article-title":"STATs in cancer inflammation and immunity: a leading role for STAT3","volume":"9","author":"Yu","year":"2009","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.phymed.2025.157210_bib0044","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2024.1445304","article-title":"Causality investigation among gut microbiota, immune cells, and prostate diseases: a mendelian randomization study","volume":"15","author":"Yue","year":"2024","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.phymed.2025.157210_bib0045","doi-asserted-by":"crossref","DOI":"10.3390\/ijms20194790","article-title":"Polyamine catabolism in acute kidney injury","volume":"20","author":"Zahedi","year":"2019","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.phymed.2025.157210_bib0046","doi-asserted-by":"crossref","first-page":"14006","DOI":"10.1096\/fj.201902910RRR","article-title":"CaMK4-dependent phosphorylation of akt\/mTOR underlies Th17 excessive activation in experimental autoimmune prostatitis","volume":"34","author":"Zhan","year":"2020","journal-title":"FASEB J."},{"key":"10.1016\/j.phymed.2025.157210_bib0047","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2019.109591","article-title":"Prebiotic, immuno-stimulating and gut microbiota-modulating effects of Lycium barbarum polysaccharide","volume":"121","author":"Zhu","year":"2020","journal-title":"Biomed. PharmacOther"},{"key":"10.1016\/j.phymed.2025.157210_bib0048","doi-asserted-by":"crossref","first-page":"3445","DOI":"10.3892\/mmr.2014.3128","article-title":"Effects of Lycium barbarum polysaccharides on oxidative stress in hyperlipidemic mice following chronic composite psychological stress intervention","volume":"11","author":"Zhu","year":"2015","journal-title":"Mol. Med. Rep."},{"key":"10.1016\/j.phymed.2025.157210_bib0049","article-title":"The role of Th17 cells in endocrine organs: involvement of the gut, adipose tissue, liver and bone","volume":"13","author":"Zi","year":"2022","journal-title":"Front. Immunol."},{"key":"10.1016\/j.phymed.2025.157210_bib0050","doi-asserted-by":"crossref","first-page":"964","DOI":"10.14336\/AD.2022.1127","article-title":"Gut microbiota is an impact factor based on the brain-Gut axis to Alzheimer's Disease: a systematic review","volume":"14","author":"Zou","year":"2023","journal-title":"Aging Dis."}],"container-title":["Phytomedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0944711325008499?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0944711325008499?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T16:32:38Z","timestamp":1778776358000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0944711325008499"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11]]},"references-count":50,"alternative-id":["S0944711325008499"],"URL":"https:\/\/doi.org\/10.1016\/j.phymed.2025.157210","relation":{},"ISSN":["0944-7113"],"issn-type":[{"value":"0944-7113","type":"print"}],"subject":[],"published":{"date-parts":[[2025,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Lycium barbarum polysaccharides alleviate experimental autoimmune prostatitis by putrescine\/TRAF\/JAK\/STAT-mediated Th17 differentiation","name":"articletitle","label":"Article Title"},{"value":"Phytomedicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.phymed.2025.157210","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier GmbH. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"157210"}}