{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T22:29:08Z","timestamp":1792621748920,"version":"4.5.0"},"reference-count":71,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100008402","name":"Chengdu University of Traditional Chinese Medicine","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008402","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004829","name":"Science and Technology Department of Sichuan Province","doi-asserted-by":"publisher","award":["2024NSFSC0701"],"award-info":[{"award-number":["2024NSFSC0701"]}],"id":[{"id":"10.13039\/501100004829","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Phytomedicine"],"published-print":{"date-parts":[[2025,11]]},"DOI":"10.1016\/j.phymed.2025.157229","type":"journal-article","created":{"date-parts":[[2025,9,4]],"date-time":"2025-09-04T15:34:10Z","timestamp":1757000050000},"page":"157229","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"C","title":["Association between systemic immune-inflammation indexes and Nuodikang capsule\u2019s protection in LPS-induced acute lung injury in mice"],"prefix":"10.1016","volume":"147","author":[{"given":"Fuhan","family":"Fan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuying","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jierui","family":"Yan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaobo","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chuan","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dongsheng","family":"Ren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xianli","family":"Meng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ya","family":"Hou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.phymed.2025.157229_bib0001","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2021.108036","article-title":"Anti-SARS-CoV-2 and anti-cytokine storm neutralizing antibody therapies against COVID-19: update, challenges, and perspectives","volume":"99","author":"Batista","year":"2021","journal-title":"Int. Immunopharmacol."},{"issue":"5","key":"10.1016\/j.phymed.2025.157229_bib0002","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1165\/rcmb.2011-0392TR","article-title":"Role of chemokines in the pathogenesis of acute lung injury","volume":"46","author":"Bhatia","year":"2012","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"issue":"4","key":"10.1016\/j.phymed.2025.157229_bib0003","doi-asserted-by":"crossref","first-page":"345","DOI":"10.5858\/arpa.2015-0519-RA","article-title":"Acute lung injury: a clinical and molecular review","volume":"140","author":"Butt","year":"2016","journal-title":"Arch. Pathol. Lab. Med."},{"key":"10.1016\/j.phymed.2025.157229_bib0004","article-title":"Tibetan medicine Duoxuekang aapsule ameliorates high-altitude polycythemia accompanied by brain injury","volume":"12","author":"Chen","year":"2021","journal-title":"Front. Pharmacol."},{"issue":"1","key":"10.1016\/j.phymed.2025.157229_bib0005","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1186\/s10020-022-00502-8","article-title":"FGF1 alleviates LPS-induced acute lung injury via suppression of inflammation and oxidative stress","volume":"28","author":"Dhlamini","year":"2022","journal-title":"Mol. Med."},{"issue":"4","key":"10.1016\/j.phymed.2025.157229_bib0006","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1021\/acs.jproteome.1c00647","article-title":"Uncovering the metabolic mechanism of salidroside alleviating microglial hypoxia inflammation based on microfluidic chip-mass spectrometry","volume":"21","author":"Fan","year":"2022","journal-title":"J. Proteome Res."},{"key":"10.1016\/j.phymed.2025.157229_bib0007","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2020.110458","article-title":"Salidroside as a potential neuroprotective agent for ischemic stroke: a review of sources, pharmacokinetics, mechanism and safety","volume":"129","author":"Fan","year":"2020","journal-title":"Biomed. Pharmacother."},{"issue":"1","key":"10.1016\/j.phymed.2025.157229_bib0008","doi-asserted-by":"crossref","first-page":"131","DOI":"10.3892\/ijmm.2020.4599","article-title":"MicroRNA-17 contributes to the suppression of the inflammatory response in lipopolysaccharide-induced acute lung injury in mice via targeting the toll-like receptor 4\/nuclear factor-\u03baB pathway","volume":"46","author":"Fu","year":"2020","journal-title":"Int. J. Mol. Med."},{"key":"10.1016\/j.phymed.2025.157229_bib0009","doi-asserted-by":"crossref","DOI":"10.1016\/j.cbi.2024.111085","article-title":"Kaempferol mitigates sepsis-induced acute lung injury by modulating the SphK1\/S1P\/S1PR1\/MLC2 signaling pathway to restore the integrity of the pulmonary endothelial cell barrier","volume":"398","author":"Gao","year":"2024","journal-title":"Chem.-Biol. Interact."},{"key":"10.1016\/j.phymed.2025.157229_bib0010","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2024.116233","article-title":"S100A9-\/- alleviates LPS-induced acute lung injury by regulating M1 macrophage polarization and inhibiting pyroptosis via the TLR4\/MyD88\/NF-\u03baB signaling axis","volume":"172","author":"Gong","year":"2024","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.phymed.2025.157229_bib0011","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1186\/s13054-015-0782-3","article-title":"Neutralization of osteopontin attenuates neutrophil migration in sepsis-induced acute lung injury","volume":"19","author":"Hirano","year":"2015","journal-title":"Crit. Care"},{"key":"10.1016\/j.phymed.2025.157229_bib0012","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2024.155529","article-title":"Rhodiola crenulata alleviates hypobaric hypoxia-induced brain injury by maintaining BBB integrity and balancing energy metabolism dysfunction","volume":"128","author":"Hou","year":"2024","journal-title":"Phytomedicine"},{"key":"10.1016\/j.phymed.2025.157229_bib0013","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2022.154568","article-title":"Salidroside intensifies mitochondrial function of CoCl2-damaged HT22 cells by stimulating PI3K-AKT-MAPK signaling pathway","volume":"109","author":"Hou","year":"2023","journal-title":"Phytomedicine"},{"key":"10.1016\/j.phymed.2025.157229_bib0014","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2022.120782","article-title":"Deciphering the role of damage-associated molecular patterns and inflammatory responses in acute lung injury","volume":"305","author":"Hsieh","year":"2022","journal-title":"Life Sci."},{"key":"10.1016\/j.phymed.2025.157229_bib0015","doi-asserted-by":"crossref","first-page":"5709","DOI":"10.2147\/DDDT.S499037","article-title":"Quercetin: a flavonoid with potential for treating acute lung injury","volume":"18","author":"Huang","year":"2024","journal-title":"Drug Des. Dev. Ther."},{"issue":"1","key":"10.1016\/j.phymed.2025.157229_bib0016","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1186\/s13054-020-03112-0","article-title":"Incidence and outcomes of acute respiratory distress syndrome in intensive care units of mainland China: a multicentre prospective longitudinal study","volume":"24","author":"Huang","year":"2020","journal-title":"Crit. Care"},{"key":"10.1016\/j.phymed.2025.157229_bib0017","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2024.155997","article-title":"Xuanfei Baidu decoction ameliorates bleomycin-elicited idiopathic pulmonary fibrosis in mice by regulating the lung-gut crosstalk via IFN\u03b3\/STAT1\/STAT3 axis","volume":"135","author":"Jia","year":"2024","journal-title":"Phytomedicine"},{"key":"10.1016\/j.phymed.2025.157229_bib0018","doi-asserted-by":"crossref","DOI":"10.3389\/fphys.2022.1009607","article-title":"Time-dependent alteration in the chemoreflex post-acute lung injury","volume":"13","author":"Kamra","year":"2022","journal-title":"Front. Physiol."},{"issue":"1","key":"10.1016\/j.phymed.2025.157229_bib0019","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/cimb46010001","article-title":"Gallic acid protects from sepsis-induced acute lung injury","volume":"46","author":"Kardas","year":"2024","journal-title":"Curr. Issues Mol. Biol."},{"key":"10.1016\/j.phymed.2025.157229_bib0020","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1016\/j.fct.2017.09.053","article-title":"Tyrosol attenuates lipopolysaccharide-induced acute lung injury by inhibiting the inflammatory response and maintaining the alveolar capillary barrier","volume":"109","author":"Kim","year":"2017","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.phymed.2025.157229_bib0021","doi-asserted-by":"crossref","first-page":"1722","DOI":"10.3389\/fimmu.2020.01722","article-title":"Pulmonary innate immune response determines the outcome of inflammation during pneumonia and sepsis-associated acute lung injury","volume":"11","author":"Kumar","year":"2020","journal-title":"Front. Immunol."},{"issue":"5","key":"10.1016\/j.phymed.2025.157229_bib0022","doi-asserted-by":"crossref","first-page":"2374","DOI":"10.1002\/ptr.8062","article-title":"Jatrorrhizine alleviates cytokine storm secondary lung injury via regulating CD39-dominant purinergic braking and downstream NLRP3 inflammasome","volume":"39","author":"Lan","year":"2025","journal-title":"Phytother. Res."},{"key":"10.1016\/j.phymed.2025.157229_bib0023","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2024.155376","article-title":"Salidroside protects pulmonary artery endothelial cells against hypoxia-induced apoptosis via the AhR\/NF-\u03baB and Nrf2\/HO-1 pathways","volume":"128","author":"Lei","year":"2024","journal-title":"Phytomedicine"},{"issue":"4","key":"10.1016\/j.phymed.2025.157229_bib0024","doi-asserted-by":"crossref","first-page":"2251","DOI":"10.1128\/JVI.06209-11","article-title":"Natural killer cells are involved in acute lung immune injury caused by respiratory syncytial virus infection","volume":"86","author":"Li","year":"2012","journal-title":"J. Virol."},{"issue":"1","key":"10.1016\/j.phymed.2025.157229_bib0025","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1186\/s11658-022-00318-8","article-title":"Obacunone alleviates ferroptosis during lipopolysaccharide-induced acute lung injury by upregulating Nrf2-dependent antioxidant responses","volume":"27","author":"Li","year":"2022","journal-title":"Cell. Mol. Biol. Lett."},{"key":"10.1016\/j.phymed.2025.157229_bib0026","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/j.jare.2024.02.023","article-title":"Baicalein induces apoptosis by inhibiting the glutamine-mTOR metabolic pathway in lung cancer","volume":"68","author":"Li","year":"2025","journal-title":"J. Adv. Res."},{"key":"10.1016\/j.phymed.2025.157229_bib0027","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2020.113629","article-title":"Tibetan medicine Duoxuekang ameliorates hypobaric hypoxia-induced brain injury in mice by restoration of cerebrovascular function","volume":"270","author":"Li","year":"2021","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.phymed.2025.157229_bib0028","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.molimm.2024.02.001","article-title":"Hydrogen ameliorates endotoxin-induced acute lung injury through AMPK-mediated bidirectional regulation of Caspase3","volume":"168","author":"Li","year":"2024","journal-title":"Mol. Immunol."},{"issue":"1","key":"10.1016\/j.phymed.2025.157229_bib0029","doi-asserted-by":"crossref","first-page":"6690","DOI":"10.1038\/s41598-025-90870-y","article-title":"Suzi Daotan decoction alleviates asthmatic airway remodeling through the AMPK\/SIRT1\/PGC-1\u03b1 signaling pathway and PI3K\/AKT signaling pathway","volume":"15","author":"Liu","year":"2025","journal-title":"Sci. Rep."},{"issue":"4","key":"10.1016\/j.phymed.2025.157229_bib0030","doi-asserted-by":"crossref","first-page":"303","DOI":"10.3892\/etm.2021.9734","article-title":"Diammonium glycyrrhizinate lipid ligand ameliorates lipopolysaccharide-induced acute lung injury by modulating vascular endothelial barrier function","volume":"21","author":"Liu","year":"2021","journal-title":"Exp. Ther. Med."},{"issue":"10","key":"10.1016\/j.phymed.2025.157229_bib0031","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1042\/CS20210879","article-title":"Pathogenesis of pneumonia and acute lung injury","volume":"136","author":"Long","year":"2022","journal-title":"Clin. Sci."},{"issue":"1","key":"10.1016\/j.phymed.2025.157229_bib0032","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1186\/s12967-020-02410-z","article-title":"Mesenchymal stem cells activate Notch signaling to induce regulatory dendritic cells in LPS-induced acute lung injury","volume":"18","author":"Lu","year":"2020","journal-title":"J. Transl. Med."},{"issue":"5","key":"10.1016\/j.phymed.2025.157229_bib0033","doi-asserted-by":"crossref","first-page":"1763","DOI":"10.1021\/acsbiomaterials.2c00026","article-title":"Dexamethasone: insights into pharmacological aspects, therapeutic mechanisms, and delivery systems","volume":"8","author":"Madamsetty","year":"2022","journal-title":"Acs Biomater. Sci. Eng."},{"issue":"10300","key":"10.1016\/j.phymed.2025.157229_bib0034","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1016\/S0140-6736(21)00439-6","article-title":"Acute respiratory distress syndrome","volume":"398","author":"Meyer","year":"2021","journal-title":"Lancet"},{"issue":"4","key":"10.1016\/j.phymed.2025.157229_bib0035","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1165\/rcmb.2019-0399OC","article-title":"Impact of regulatory T cells on type 2 alveolar epithelial cell transcriptomes during resolution of acute lung injury and contributions of IFN-\u03b3","volume":"63","author":"Mock","year":"2020","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"key":"10.1016\/j.phymed.2025.157229_bib0036","first-page":"S353","article-title":"Acute lung injury - from pathophysiology to treatment","volume":"69","author":"Mokra","year":"2020","journal-title":"Physiol. Res."},{"issue":"5","key":"10.1016\/j.phymed.2025.157229_bib0037","doi-asserted-by":"crossref","DOI":"10.1016\/j.cpsurg.2020.100777","article-title":"Acute lung injury","volume":"57","author":"Mowery","year":"2020","journal-title":"Curr. Probl. Surg."},{"issue":"1","key":"10.1016\/j.phymed.2025.157229_bib0038","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1186\/s10020-022-00500-w","article-title":"ISM1 suppresses LPS-induced acute lung injury and post-injury lung fibrosis in mice","volume":"28","author":"Nguyen","year":"2022","journal-title":"Mol. Med."},{"issue":"11","key":"10.1016\/j.phymed.2025.157229_bib0039","doi-asserted-by":"crossref","DOI":"10.21037\/jtd-24-680","article-title":"Exacerbation of pulmonary fibrosis following acute lung injury via activin-A production by recruited alveolar macrophages","volume":"16","author":"Pan","year":"2024","journal-title":"J. Thorac. Dis."},{"issue":"7","key":"10.1016\/j.phymed.2025.157229_bib0040","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1016\/j.phymed.2010.02.002","article-title":"Rosenroot (Rhodiola rosea): traditional use, chemical composition, pharmacology and clinical efficacy","volume":"17","author":"Panossian","year":"2010","journal-title":"Phytomedicine"},{"key":"10.1016\/j.phymed.2025.157229_bib0041","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2019.109552","article-title":"Anti-inflammatory effects of Rhodiola rosea L.: a review","volume":"121","author":"Pu","year":"2020","journal-title":"Biomed. Pharmacother."},{"issue":"1","key":"10.1016\/j.phymed.2025.157229_bib0042","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1186\/s12964-024-01620-y","article-title":"Endothelial cell dynamics in sepsis-induced acute lung injury and acute respiratory distress syndrome: pathogenesis and therapeutic implications","volume":"22","author":"Qiao","year":"2024","journal-title":"Cell Commun. Signal."},{"issue":"5","key":"10.1016\/j.phymed.2025.157229_bib0043","article-title":"B-cells in pulmonary arterial hypertension: friend, foe or bystander?","volume":"63","author":"Sanges","year":"2024","journal-title":"Eur. Respir. J."},{"issue":"1","key":"10.1016\/j.phymed.2025.157229_bib0044","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1021\/acs.jmedchem.4c02030","article-title":"Design, synthesis, and biological evaluation of 2-arylaminopyrimidine derivatives as dual cathepsin L and JAK inhibitors for the treatment of acute lung injury","volume":"68","author":"Shen","year":"2024","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.phymed.2025.157229_bib0045","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2021.111949","article-title":"Salidroside attenuates acute lung injury via inhibition of inflammatory cytokine production","volume":"142","author":"Song","year":"2021","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.phymed.2025.157229_bib0046","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2024.155965","article-title":"Lentinan attenuates allergic airway inflammation and epithelial barrier dysfunction in asthma via inhibition of the PI3K\/AKT\/NF-\u03baB pathway","volume":"134","author":"Song","year":"2024","journal-title":"Phytomedicine"},{"issue":"2","key":"10.1016\/j.phymed.2025.157229_bib0047","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1111\/crj.13449","article-title":"Respiratory muscle weakness and its association with exercise capacity in patients with chronic obstructive pulmonary disease","volume":"16","author":"Souza","year":"2022","journal-title":"Clin. Respir. J."},{"key":"10.1016\/j.phymed.2025.157229_bib0048","doi-asserted-by":"crossref","DOI":"10.3389\/fphys.2021.690265","article-title":"Automated classification of whole body plethysmography waveforms to quantify breathing patterns","volume":"12","author":"Sunshine","year":"2021","journal-title":"Front. Physiol."},{"key":"10.1016\/j.phymed.2025.157229_bib0049","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejphar.2021.174617","article-title":"Salidroside attenuates CoCl2-simulated hypoxia injury in PC12 cells partly by mitochondrial protection","volume":"912","author":"Tang","year":"2021","journal-title":"Eur. J. Pharmacol."},{"issue":"8021","key":"10.1016\/j.phymed.2025.157229_bib0050","doi-asserted-by":"crossref","DOI":"10.1038\/s41586-024-07660-1","article-title":"Alveolar fibroblast lineage orchestrates lung inflammation and fibrosis","volume":"631","author":"Tsukui","year":"2024","journal-title":"Nature"},{"key":"10.1016\/j.phymed.2025.157229_bib0051","doi-asserted-by":"crossref","DOI":"10.1016\/j.rmed.2020.106272","article-title":"Pulmonary function and health-related quality of life after COVID-19 pneumonia","volume":"176","author":"Van der Sar-van der Brugge","year":"2021","journal-title":"Respir. Med."},{"issue":"5","key":"10.1016\/j.phymed.2025.157229_bib0052","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1248\/bpb.b16-00756","article-title":"Protective effects of tyrosol against LPS-induced acute lung injury via inhibiting NF-\u03baB and AP-1 activation and activating the HO-1\/Nrf2 pathways","volume":"40","author":"Wang","year":"2017","journal-title":"Biol. Pharm. Bull."},{"key":"10.1016\/j.phymed.2025.157229_bib0053","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2024.155591","article-title":"Syringic acid attenuates acute lung injury by modulating macrophage polarization in LPS-induced mice","volume":"129","author":"Wang","year":"2024","journal-title":"Phytomedicine"},{"issue":"11","key":"10.1016\/j.phymed.2025.157229_bib0054","doi-asserted-by":"crossref","first-page":"1284","DOI":"10.1002\/alr.22207","article-title":"Gallic acid attenuates allergic airway inflammation via suppressed interleukin-33 and group 2 innate lymphoid cells in ovalbumin-induced asthma in mice","volume":"8","author":"Wang","year":"2018","journal-title":"Int. Forum Allergy Rhinol."},{"key":"10.1016\/j.phymed.2025.157229_bib0055","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2022.115278","article-title":"Salidroside, a phenyl ethanol glycoside from Rhodiola crenulata, orchestrates hypoxic mitochondrial dynamics homeostasis by stimulating Sirt1\/p53\/Drp1 signaling","volume":"293","author":"Wang","year":"2022","journal-title":"J. Ethnopharmacol."},{"issue":"8","key":"10.1016\/j.phymed.2025.157229_bib0056","doi-asserted-by":"crossref","first-page":"2055","DOI":"10.1038\/s41401-021-00813-2","article-title":"STING inhibitor ameliorates LPS-induced ALI by preventing vascular endothelial cells-mediated immune cells chemotaxis and adhesion","volume":"43","author":"Wu","year":"2022","journal-title":"Acta Pharmacol. Sin."},{"issue":"6","key":"10.1016\/j.phymed.2025.157229_bib0057","doi-asserted-by":"crossref","first-page":"2928","DOI":"10.7150\/thno.69533","article-title":"AdMSC-derived exosomes alleviate acute lung injury via transferring mitochondrial component to improve homeostasis of alveolar macrophages","volume":"12","author":"Xia","year":"2022","journal-title":"Theranostics"},{"key":"10.1016\/j.phymed.2025.157229_bib0058","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2022.154240","article-title":"Rhodiola crenulate alleviates hypobaric hypoxia-induced brain injury via adjusting NF-\u03baB\/NLRP3-mediated inflammation","volume":"103","author":"Xie","year":"2022","journal-title":"Phytomedicine"},{"key":"10.1016\/j.phymed.2025.157229_bib0059","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2023.116572","article-title":"Integrating UPLC-Q-exactive orbitrap\/MS, network pharmacology and experimental validation to reveal the potential mechanism of Tibetan medicine Rhodiola granules in improving myocardial ischemia-reperfusion injury","volume":"314","author":"Xing","year":"2023","journal-title":"J. Ethnopharmacol."},{"issue":"4","key":"10.1016\/j.phymed.2025.157229_bib0060","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1038\/s41374-018-0170-0","article-title":"Glucagon-like peptide-1 receptor activation alleviates lipopolysaccharide-induced acute lung injury in mice via maintenance of endothelial barrier function","volume":"99","author":"Xu","year":"2019","journal-title":"Lab. Investig."},{"key":"10.1016\/j.phymed.2025.157229_bib0061","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2022.114988","article-title":"Dengzhan Xixin injection derived from a traditional Chinese herb Erigeron breviscapus ameliorates cerebral ischemia\/reperfusion injury in rats via modulation of mitophagy and mitochondrial apoptosis","volume":"288","author":"Yang","year":"2022","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.phymed.2025.157229_bib0062","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2024.117831","article-title":"A novel mechanism for regulating lung immune homeostasis: zukamu granules alleviated acute lung injury in mice by inhibiting NLRP3 inflammasome activation and regulating Th17\/Treg cytokine balance","volume":"324","author":"Yu","year":"2024","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.phymed.2025.157229_bib0063","article-title":"Noninvasive intratracheal lipopolysaccharide instillation in mice","volume":"193","author":"Yu","year":"2023","journal-title":"Jove-J. Vis. Exp."},{"issue":"9","key":"10.1016\/j.phymed.2025.157229_bib0064","doi-asserted-by":"crossref","DOI":"10.1002\/ctm2.70027","article-title":"IBR1, a novel endogenous IFIH1-binding dsRNA, governs IFIH1 activation and M1 macrophage polarisation in ARDS","volume":"14","author":"Zhang","year":"2024","journal-title":"Clin. Transl. Med."},{"issue":"1","key":"10.1016\/j.phymed.2025.157229_bib0065","doi-asserted-by":"crossref","first-page":"247","DOI":"10.14336\/AD.2020.0410","article-title":"The role of immune cells in the pathogenesis of idiopathic inflammatory myopathies","volume":"12","author":"Zhao","year":"2021","journal-title":"Aging Dis."},{"key":"10.1016\/j.phymed.2025.157229_bib0066","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/j.jconrel.2022.03.025","article-title":"Inhalation of MSC-EVs is a noninvasive strategy for ameliorating acute lung injury","volume":"345","author":"Zhao","year":"2022","journal-title":"J. Control. Release"},{"key":"10.1016\/j.phymed.2025.157229_bib0067","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2024.116773","article-title":"Exploring immune-related pathogenesis in lung injury: providing new insights Into ALI\/ARDS","volume":"175","author":"Zheng","year":"2024","journal-title":"Biomed. Pharmacother."},{"issue":"1","key":"10.1016\/j.phymed.2025.157229_bib0068","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1186\/s13054-019-2339-3","article-title":"Exosomes from endothelial progenitor cells improve outcomes of the lipopolysaccharide-induced acute lung injury","volume":"23","author":"Zhou","year":"2019","journal-title":"Crit. Care"},{"issue":"10","key":"10.1016\/j.phymed.2025.157229_bib0069","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1038\/s41419-020-03036-1","article-title":"Mesenchymal stem cells alleviate LPS-induced acute lung injury by inhibiting the proinflammatory function of Ly6C+ CD8+ T cells","volume":"11","author":"Zhu","year":"2020","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.phymed.2025.157229_bib0070","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2022.1103309","article-title":"Immunotherapy strategies and prospects for acute lung injury: focus on immune cells and cytokines","volume":"13","author":"Zhu","year":"2022","journal-title":"Front. Pharmacol."},{"issue":"3","key":"10.1016\/j.phymed.2025.157229_bib0071","doi-asserted-by":"crossref","first-page":"1601","DOI":"10.1007\/s00210-023-02705-0","article-title":"Costunolide attenuates LPS-induced inflammation and lung injury through inhibiting IKK\/NF-kappaB signaling","volume":"397","author":"Zhu","year":"2024","journal-title":"Naunyn-Schmiedeberg's Arch. Pharmacol."}],"container-title":["Phytomedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0944711325008682?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0944711325008682?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T16:25:11Z","timestamp":1773419111000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0944711325008682"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11]]},"references-count":71,"alternative-id":["S0944711325008682"],"URL":"https:\/\/doi.org\/10.1016\/j.phymed.2025.157229","relation":{},"ISSN":["0944-7113"],"issn-type":[{"value":"0944-7113","type":"print"}],"subject":[],"published":{"date-parts":[[2025,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Association between systemic immune-inflammation indexes and Nuodikang capsule\u2019s protection in LPS-induced acute lung injury in mice","name":"articletitle","label":"Article Title"},{"value":"Phytomedicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.phymed.2025.157229","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier GmbH. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"157229"}}