{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T20:04:49Z","timestamp":1779912289826,"version":"3.53.1"},"reference-count":55,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100010971","name":"Yunnan Province","doi-asserted-by":"publisher","award":["YNWR QNbJ-2020-246"],"award-info":[{"award-number":["YNWR QNbJ-2020-246"]}],"id":[{"id":"10.13039\/501100010971","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010971","name":"Yunnan Province","doi-asserted-by":"publisher","award":["202401AT070353"],"award-info":[{"award-number":["202401AT070353"]}],"id":[{"id":"10.13039\/501100010971","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010971","name":"Yunnan Province","doi-asserted-by":"publisher","award":["YNWR-QNbJ-2020-226"],"award-info":[{"award-number":["YNWR-QNbJ-2020-226"]}],"id":[{"id":"10.13039\/501100010971","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010971","name":"Yunnan Province","doi-asserted-by":"publisher","award":["202401AS070608"],"award-info":[{"award-number":["202401AS070608"]}],"id":[{"id":"10.13039\/501100010971","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010971","name":"Yunnan Province","doi-asserted-by":"publisher","award":["2022SCP003"],"award-info":[{"award-number":["2022SCP003"]}],"id":[{"id":"10.13039\/501100010971","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Phytomedicine"],"published-print":{"date-parts":[[2026,4]]},"DOI":"10.1016\/j.phymed.2026.157942","type":"journal-article","created":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T00:27:03Z","timestamp":1771288023000},"page":"157942","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Rosa chinensis cv. \u2018JinBian\u2019 flowers alleviates brain damage and cognitive deficit by inhibiting ferroptosis via the Keap1\/Nrf2\/GPX4 pathway and regulating gut microbiota"],"prefix":"10.1016","volume":"153","author":[{"given":"Li","family":"Zhen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianhong","family":"Peng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huimin","family":"Cui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junhong","family":"Tao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaping","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianxin","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hesham R","family":"El-Seedi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guiguang","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhengxuan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.phymed.2026.157942_bib0001","doi-asserted-by":"crossref","DOI":"10.3389\/fped.2021.652208","article-title":"Fecal and duodenal microbiota in pediatric celiac disease","volume":"9","author":"Abdukhakimova","year":"2021","journal-title":"Front. Pediatr."},{"issue":"14","key":"10.1016\/j.phymed.2026.157942_bib0002","doi-asserted-by":"crossref","first-page":"16089","DOI":"10.1021\/acsomega.3c09792","article-title":"Evaluation of the binding mechanism of dietary phytochemical, ellagic acid, with human transferrin: spectroscopic, calorimetric, and computational approaches targeting neurodegenerative diseases","volume":"9","author":"Alrouji","year":"2024","journal-title":"ACS Omega"},{"issue":"3","key":"10.1016\/j.phymed.2026.157942_bib0004","doi-asserted-by":"crossref","first-page":"1206","DOI":"10.1002\/fft2.261","article-title":"Targeting mitochondrial quality control in muscle aging: Natural dietary products as potential interventions","volume":"4","author":"Chen","year":"2023","journal-title":"Food Front"},{"key":"10.1016\/j.phymed.2026.157942_bib0005","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodres.2025.116323","article-title":"E se tea aqueous-ethanol extract ameliorates D-galactose induced oxidative stress and inflammation via the Nrf2 signal pathway","volume":"209","author":"Cheng","year":"2025","journal-title":"Food Res. Int."},{"key":"10.1016\/j.phymed.2026.157942_bib0006","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2023.155101","article-title":"Natural products for the treatment of neurodegenerative diseases","volume":"121","author":"Cui","year":"2023","journal-title":"Phytomedicine"},{"key":"10.1016\/j.phymed.2026.157942_bib0007","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2024.155942","article-title":"Lingguizhugan decoction ameliorates cognitive impairment in AD-like mice by influencing the microbiome\u2013gut\u2013brain axis mediated by SCFAs","volume":"133","author":"Du","year":"2024","journal-title":"Phytomedicine"},{"key":"10.1016\/j.phymed.2026.157942_bib0008","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodchem.2020.126512","article-title":"UHPLC-ESI-HRMS\/MS analysis on phenolic compositions of different E Se tea extracts and their antioxidant and cytoprotective activities","volume":"318","author":"Fan","year":"2020","journal-title":"Food Chem."},{"issue":"9","key":"10.1016\/j.phymed.2026.157942_bib0009","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1038\/cr.2016.95","article-title":"Ferroptosis is an autophagic cell death process","volume":"26","author":"Gao","year":"2016","journal-title":"Cell Res."},{"key":"10.1016\/j.phymed.2026.157942_bib0010","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodchem.2021.131752","article-title":"Phenolic constituents, antioxidant activity and neuroprotective effects of ethanol extracts of fruits, leaves and flower buds from Vaccinium dunalianum wight","volume":"374","author":"Gao","year":"2022","journal-title":"Food Chem."},{"key":"10.1016\/j.phymed.2026.157942_bib0011","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2022.154365","article-title":"Ginseng under forest exerts stronger anti-aging effects compared to garden ginseng probably via regulating PI3K\/AKT\/mTOR pathway, SIRT1\/NF-\u03baB pathway and intestinal flora","volume":"105","author":"Hao","year":"2022","journal-title":"Phytomedicine"},{"key":"10.1016\/j.phymed.2026.157942_bib0012","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodres.2022.111977","article-title":"Edible rose flowers: a doorway to gastronomic and nutraceutical research","volume":"162","author":"Hegde","year":"2022","journal-title":"Food Res. Int."},{"issue":"1","key":"10.1016\/j.phymed.2026.157942_bib0013","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1186\/s12967-024-05120-y","article-title":"Quinic acid regulated TMA\/TMAO-related lipid metabolism and vascular endothelial function through gut microbiota to inhibit atherosclerotic","volume":"22","author":"Jin","year":"2024","journal-title":"J. Transl. Med."},{"issue":"2","key":"10.1016\/j.phymed.2026.157942_bib0014","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1080\/08830185.2018.1450947","article-title":"In this issue: Effect of gut microbiome on mucosal immunity and enteric diseases","volume":"37","author":"Kumar","year":"2018","journal-title":"Int. Rev. Immunol."},{"key":"10.1016\/j.phymed.2026.157942_bib0015","doi-asserted-by":"crossref","first-page":"654","DOI":"10.3390\/antiox13060654","article-title":"Preliminary investigation of Astragalus arpilobus subsp. hauarensis: LC-MS\/MS chemical profiling, in vitro evaluation of antioxidant, anti-inflammatory properties, cytotoxicity, and in silico analysis against COX-2","volume":"13","author":"Lekmine","year":"2024","journal-title":"Antioxidants"},{"key":"10.1016\/j.phymed.2026.157942_bib0016","doi-asserted-by":"crossref","DOI":"10.1016\/j.indcrop.2020.112922","article-title":"Targeted isolation of terpenoid indole alkaloids from Melodinus cochinchinensis (Lour.) Merr. using molecular networking and their biological activities","volume":"157","author":"Li","year":"2020","journal-title":"Ind. Crops Prod."},{"key":"10.1016\/j.phymed.2026.157942_bib0017","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodchem.2023.135978","article-title":"Acteoside palliates d-galactose induced cognitive impairment by regulating intestinal homeostasis","volume":"421","author":"Li","year":"2023","journal-title":"Food Chem."},{"key":"10.1016\/j.phymed.2026.157942_bib0018","doi-asserted-by":"crossref","DOI":"10.1016\/j.indcrop.2020.113059","article-title":"Anti-aging potential, anti-tyrosinase and antibacterial activities of extracts and compounds isolated from Rosa chinensis cv. \u2018JinBian\u2019","volume":"159","author":"Li","year":"2021","journal-title":"Ind. Crops Prod."},{"key":"10.1016\/j.phymed.2026.157942_bib0019","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodres.2025.116572","article-title":"Anti-aging effect of tea and its phytochemicals","volume":"214","author":"Liang","year":"2025","journal-title":"Food Res. Int."},{"key":"10.1016\/j.phymed.2026.157942_bib0020","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1186\/s10020-024-00825-8","article-title":"AMPK activation eliminates senescent cells in diabetic wound by inducing NCOA4 mediated ferritinophagy","volume":"30","author":"Liu","year":"2024","journal-title":"Mol. Med."},{"issue":"27","key":"10.1016\/j.phymed.2026.157942_bib0021","doi-asserted-by":"crossref","first-page":"16890","DOI":"10.1021\/acs.jafc.5c00835","article-title":"Flavonoids from Shiliangcha (Chimonanthus salicifolius) alleviate brain aging in D-galactose-induced senescent mice through gut microbiota","volume":"73","author":"Liu","year":"2025","journal-title":"J. Agric. Food Chem."},{"issue":"127","key":"10.1016\/j.phymed.2026.157942_bib0022","first-page":"221","article-title":"N-methyl-D-aspartate receptors mediate epilepsy-induced axonal impairment and tau phosphorylation via activating glycogen synthase kinase-3\u03b2 and cyclin-dependent kinase 5","volume":"23","author":"Liu","year":"2017","journal-title":"Discov. Med."},{"issue":"1","key":"10.1016\/j.phymed.2026.157942_bib0023","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1039\/C5FO00913H","article-title":"Quercitrin offers protection against brain injury in mice by inhibiting oxidative stress and inflammation","volume":"7","author":"Ma","year":"2016","journal-title":"Food Funct."},{"key":"10.1016\/j.phymed.2026.157942_bib0024","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2025.140945","article-title":"Dynamic changes in the gut microbiota play a critical role in age-associated cognitive dysfunction via SCFAs and LPS synthesis metabolic pathways during brain aging","volume":"304","author":"Ma","year":"2025","journal-title":"Int. J. Biol. Macromol."},{"issue":"2-3","key":"10.1016\/j.phymed.2026.157942_bib0025","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.1016\/j.foodchem.2012.11.022","article-title":"Neuroprotective effects of oral gallic acid against oxidative stress induced by 6-hydroxydopamine in rats","volume":"138","author":"Mansouri","year":"2013","journal-title":"Food Chem."},{"issue":"8","key":"10.1016\/j.phymed.2026.157942_bib0026","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1038\/s41580-023-00594-y","article-title":"BCL-2 proteins in senescence: Beyond a simple target for senolysis?","volume":"24","author":"Martin","year":"2023","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.phymed.2026.157942_bib0027","first-page":"221","article-title":"Striking while the iron is hot: iron metabolism and ferroptosis in neurodegeneration. Free Radic","volume":"133","author":"Masaldan","year":"2019","journal-title":"Biol. Med."},{"issue":"1","key":"10.1016\/j.phymed.2026.157942_bib0028","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1038\/s41577-022-00727-y","article-title":"The impact of the gut microbiome on extra-intestinal autoimmune diseases","volume":"23","author":"Miyauchi","year":"2023","journal-title":"Nat. Rev. Immunol."},{"issue":"11","key":"10.1016\/j.phymed.2026.157942_bib0029","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1038\/s41580-024-00757-5","article-title":"Mechanisms of autophagy-lysosome dysfunction in neurodegenerative diseases","volume":"25","author":"Nixon","year":"2024","journal-title":"Nat. Rev. Mol. Cell Biol."},{"issue":"6265","key":"10.1016\/j.phymed.2026.157942_bib0030","doi-asserted-by":"crossref","first-page":"1214","DOI":"10.1126\/science.aac8469","article-title":"Gut microbiota and aging","volume":"350","author":"O\u2019Toole","year":"2015","journal-title":"Science"},{"issue":"1","key":"10.1016\/j.phymed.2026.157942_bib0031","doi-asserted-by":"crossref","DOI":"10.1111\/jfpp.13323","article-title":"Volatiles, polysaccharides and total polyphenols in Chinese rose tea infusions and their antioxidant activities","volume":"42","author":"Qin","year":"2018","journal-title":"Food Process. Preserv."},{"issue":"13","key":"10.1016\/j.phymed.2026.157942_bib0032","doi-asserted-by":"crossref","first-page":"2041","DOI":"10.3390\/nu16132041","article-title":"Gut-Brain Axis in Focus: Polyphenols, Microbiota, and Their influence on \u03b1-synuclein in Parkinson\u2019s disease","volume":"16","author":"Riegelman","year":"2024","journal-title":"Nutrients"},{"issue":"S1","key":"10.1016\/j.phymed.2026.157942_bib0033","doi-asserted-by":"crossref","DOI":"10.1002\/alz.086335","article-title":"Spermidine treatment attenuates systemic and gut oxidative stress, neuropathology and cognitive deficits in D-galactose induced aging rats","volume":"20","author":"Saiyasit","year":"2024","journal-title":"Alzheimer\u2019s Dement."},{"key":"10.1016\/j.phymed.2026.157942_bib0034","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2024.117937","article-title":"Water extract of moschus alleviates erastin-induced ferroptosis by regulating the Keap1\/Nrf2 pathway in HT22 cells","volume":"326","author":"Song","year":"2024","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.phymed.2026.157942_bib0035","doi-asserted-by":"crossref","DOI":"10.1016\/j.biortech.2024.131451","article-title":"Antioxidants alleviated low-temperature stress in microalgae by modulating reactive oxygen species to improve lipid production and antioxidant defense","volume":"413","author":"Song","year":"2024","journal-title":"Bioresour. Technol."},{"key":"10.1016\/j.phymed.2026.157942_bib0036","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2023.125517","article-title":"Lonicera japonica polysaccharides alleviate D-galactose-induced oxidative stress and restore gut microbiota in ICR mice","volume":"245","author":"Sun","year":"2023","journal-title":"Int. J. Biol. Macromol."},{"issue":"13","key":"10.1016\/j.phymed.2026.157942_bib0037","doi-asserted-by":"crossref","first-page":"7725","DOI":"10.1021\/acs.jafc.4c10497","article-title":"Saponins from Astragalus membranaceus (Fisch.) Bge alleviated neuronal ferroptosis in Alzheimer\u2019s disease by regulating the NOX4\/Nrf2 signaling pathway","volume":"73","author":"Wang","year":"2025","journal-title":"J. Agric. Food Chem."},{"issue":"1","key":"10.1016\/j.phymed.2026.157942_bib0038","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1002\/fsh3.12026","article-title":"Acute, subacute, and sub-chronic toxicity evaluation of Bletilla formosana tubers in rats","volume":"2","author":"Wang","year":"2024","journal-title":"Food Saf. Health"},{"key":"10.1016\/j.phymed.2026.157942_bib0039","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2022.154113","article-title":"Protective effects of E Se tea extracts against alcoholic fatty liver disease induced by high fat\/alcohol diet: in vivo biological evaluation and molecular docking study","volume":"101","author":"Wang","year":"2022","journal-title":"Phytomedicine"},{"key":"10.1016\/j.phymed.2026.157942_bib0040","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2025.156710","article-title":"6\u2032-O-caffeoylarbutin attenuates D-galactose-induced brain and liver damage in aging mice via regulating SIRT1\/NF-\u03baB pathway","volume":"141","author":"Wang","year":"2025","journal-title":"Phytomedicine"},{"key":"10.1016\/j.phymed.2026.157942_bib0041","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejmech.2022.114806","article-title":"Design, synthesis and evaluation of fused hybrids with acetylcholinesterase inhibiting and Nrf2 activating functions for Alzheimer\u2019s disease","volume":"244","author":"Wang","year":"2022","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.phymed.2026.157942_bib0042","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2023.154854","article-title":"E Se tea extract ameliorates CCl4 induced liver fibrosis via regulating Nrf2\/NF-\u03baB\/TGF-\u03b21\/Smad pathway","volume":"115","author":"Wang","year":"2023","journal-title":"Phytomedicine"},{"key":"10.1016\/j.phymed.2026.157942_bib0043","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2025.156476","article-title":"Yinaoxin granule alleviates cerebral ischemia-reperfusion injury by ferroptosis inhibition through Nrf2 pathway activation","volume":"139","author":"Weng","year":"2025","journal-title":"Phytomedicine"},{"key":"10.1016\/j.phymed.2026.157942_bib0044","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2024.155744","article-title":"Trilobatin suppresses aging-induced cognitive impairment by targeting SIRT2: Involvement of remodeling gut microbiota to mediate the brain-gut axis","volume":"130","author":"Xie","year":"2024","journal-title":"Phytomedicine"},{"issue":"1","key":"10.1016\/j.phymed.2026.157942_bib0045","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1002\/pca.3420","article-title":"Comparative study on metabolite variations of two rose teas by plant metabolomics and revealing their skin-whitening candidates by spectrum-effect relationship analysis","volume":"36","author":"Xu","year":"2025","journal-title":"Phytochem. Anal."},{"issue":"9","key":"10.1016\/j.phymed.2026.157942_bib0046","doi-asserted-by":"crossref","first-page":"1974","DOI":"10.3390\/molecules30091974","article-title":"Identification of chemical components in three types of rose essential oils based on gas chromatography-mass spectrometry (GC-MS) and chemometric methods","volume":"30","author":"Xu","year":"2025","journal-title":"Molecules"},{"key":"10.1016\/j.phymed.2026.157942_bib0047","doi-asserted-by":"crossref","DOI":"10.1016\/j.indcrop.2019.05.082","article-title":"Phenolic constituents, antioxidant and cytoprotective activities of crude extract and fractions from cultivated artichoke inflorescence","volume":"143","author":"Yang","year":"2020","journal-title":"Ind. Crops Prod."},{"issue":"8","key":"10.1016\/j.phymed.2026.157942_bib0048","doi-asserted-by":"crossref","first-page":"4095","DOI":"10.1039\/D3FO04575G","article-title":"Bifidobacterium pseudocatenulatum NCU-08 ameliorated senescence via modulation of the AMPK\/Sirt1 signaling pathway and gut microbiota in mice","volume":"15","author":"Zeng","year":"2024","journal-title":"Food Funct."},{"key":"10.1016\/j.phymed.2026.157942_bib0049","doi-asserted-by":"crossref","first-page":"1927","DOI":"10.1002\/fft2.306","article-title":"The protective effect and mechanism of mangiferin on D-galactose-induced oxidative stress and cognitive impairment in aging mice by an integrated network pharmacology and experimental validation strategy","volume":"4","author":"Zhang","year":"2023","journal-title":"Food Front."},{"key":"10.1016\/j.phymed.2026.157942_bib0050","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodchem.2021.130864","article-title":"The effect of ultra-high pretreatment on free, esterified and insoluble-bound phenolics from mango leaves and their antioxidant and cytoprotective activities","volume":"368","author":"Zhang","year":"2022","journal-title":"Food Chem."},{"key":"10.1016\/j.phymed.2026.157942_bib0051","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2022.154341","article-title":"Evaluating the effects of mitochondrial autophagy flux on ginsenoside Rg2 for delaying D-galactose induced brain aging in mice","volume":"104","author":"Zhang","year":"2022","journal-title":"Phytomedicine"},{"issue":"13","key":"10.1016\/j.phymed.2026.157942_bib0052","doi-asserted-by":"crossref","first-page":"1864","DOI":"10.26599\/FSHW.2022.9250155","article-title":"Reduction of the oxidative damage to H2O2-induced HepG2 cells via the Nrf2 signalling pathway by plant flavonoids Quercetin and Hyperoside","volume":"13","author":"Zhang","year":"2024","journal-title":"Food Sci. Hum. Wellness"},{"issue":"2","key":"10.1016\/j.phymed.2026.157942_bib0053","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1007\/s11130-023-01071-9","article-title":"Influence of ultra-high-pressure pretreatment method on chemical constituents, antioxidant and cytoprotective Activities of free, esterified, and bound phenolics from Anneslea fragrans wall leaves","volume":"78","author":"Zhen","year":"2023","journal-title":"Plant Food Hum. Nutr."},{"key":"10.1016\/j.phymed.2026.157942_bib0054","first-page":"894","article-title":"Hypoglycemic effects of Goji tea in streptozotocin-induced diabetic mice via IRS1\/PI3K\/AKT\/AMPK pathway","volume":"6-5","author":"Zhen","year":"2025","journal-title":"J. Future Foods"},{"issue":"38","key":"10.1016\/j.phymed.2026.157942_bib0055","doi-asserted-by":"crossref","first-page":"24139","DOI":"10.1021\/acs.jafc.5c06844","article-title":"Ginsenoside Rk3 alleviates neuroinflammation and gastrointestinal dysfunction in Parkinson\u2019s disease via modulation of gut microbiota-mediated butyric acid metabolism","volume":"73","author":"Zhou","year":"2025","journal-title":"J. Agric. Food Chem."},{"issue":"11","key":"10.1016\/j.phymed.2026.157942_bib0056","doi-asserted-by":"crossref","first-page":"4646","DOI":"10.1021\/acs.jafc.3c00652","article-title":"Bifidobacterium breve HNXY26M4 attenuates cognitive deficits and neuroinflammation by regulating the gut-brain axis in APP\/PS1 mice","volume":"71","author":"Zhu","year":"2023","journal-title":"J. Agric. Food Chem."}],"container-title":["Phytomedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0944711326001807?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0944711326001807?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T23:54:25Z","timestamp":1777593265000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0944711326001807"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":55,"alternative-id":["S0944711326001807"],"URL":"https:\/\/doi.org\/10.1016\/j.phymed.2026.157942","relation":{},"ISSN":["0944-7113"],"issn-type":[{"value":"0944-7113","type":"print"}],"subject":[],"published":{"date-parts":[[2026,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Rosa chinensis cv. \u2018JinBian\u2019 flowers alleviates brain damage and cognitive deficit by inhibiting ferroptosis via the Keap1\/Nrf2\/GPX4 pathway and regulating gut microbiota","name":"articletitle","label":"Article Title"},{"value":"Phytomedicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.phymed.2026.157942","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier GmbH. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"157942"}}