{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T13:37:41Z","timestamp":1793194661259,"version":"4.5.0"},"reference-count":52,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82472303"],"award-info":[{"award-number":["82472303"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82525062"],"award-info":[{"award-number":["82525062"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82321004"],"award-info":[{"award-number":["82321004"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82272344"],"award-info":[{"award-number":["82272344"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2022YFA1303501"],"award-info":[{"award-number":["2022YFA1303501"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100021171","name":"Basic and Applied Basic Research Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2024A1515011489"],"award-info":[{"award-number":["2024A1515011489"]}],"id":[{"id":"10.13039\/501100021171","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100021171","name":"Basic and Applied Basic Research Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2024A1515011320"],"award-info":[{"award-number":["2024A1515011320"]}],"id":[{"id":"10.13039\/501100021171","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Phytomedicine"],"published-print":{"date-parts":[[2026,11]]},"DOI":"10.1016\/j.phymed.2026.158711","type":"journal-article","created":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T15:20:29Z","timestamp":1786548029000},"page":"158711","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["A novel natural compound from Cleistocalyx operculatus enhances the anti-mycobacterial response by inhibiting ferroptosis"],"prefix":"10.1016","volume":"161","author":[{"given":"Ke","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-2081-9580","authenticated-orcid":false,"given":"Xue","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenxin","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3843-355X","authenticated-orcid":false,"given":"Jianguo","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-9466-4819","authenticated-orcid":false,"given":"Yaoxin","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4256-8927","authenticated-orcid":false,"given":"Zhenyu","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-4402-5589","authenticated-orcid":false,"given":"Pengli","family":"Xin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-2362-6896","authenticated-orcid":false,"given":"Xiao","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-7484-4198","authenticated-orcid":false,"given":"Zhiying","family":"Ding","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-1814-0075","authenticated-orcid":false,"given":"Minna","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5599-3068","authenticated-orcid":false,"given":"Xinying","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4188-9630","authenticated-orcid":false,"given":"Chaoying","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5973-7873","authenticated-orcid":false,"given":"Liang","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4524-1812","authenticated-orcid":false,"given":"Ying","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5935-6237","authenticated-orcid":false,"given":"Qian","family":"Wen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2810-1001","authenticated-orcid":false,"given":"Wencai","family":"Ye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5847-2375","authenticated-orcid":false,"given":"Li","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.phymed.2026.158711_bib0001","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1084\/jem.20181776","article-title":"A major role for ferroptosis in Mycobacterium tuberculosis-induced cell death and tissue necrosis","volume":"216","author":"Amaral","year":"2019","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.phymed.2026.158711_bib0002","doi-asserted-by":"crossref","DOI":"10.1084\/jem.20220504","article-title":"GPX4 regulates cellular necrosis and host resistance in mycobacterium tuberculosis infection","volume":"219","author":"Amaral","year":"2022","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.phymed.2026.158711_bib0003","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1038\/s41564-023-01523-7","article-title":"BACH1 promotes tissue necrosis and mycobacterium tuberculosis susceptibility","volume":"9","author":"Amaral","year":"2024","journal-title":"Nat. Microbiol."},{"key":"10.1016\/j.phymed.2026.158711_bib0004","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1146\/annurev.arplant.55.031903.141701","article-title":"Reactive oxygen species: metabolism, oxidative stress, and signal transduction","volume":"55","author":"Apel","year":"2004","journal-title":"Annu Rev. Plant Biol."},{"key":"10.1016\/j.phymed.2026.158711_bib0005","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1080\/20477724.2020.1751388","article-title":"Is glucose-6-phosphate dehydrogenase enzyme deficiency a factor in Coronavirus-19 (COVID-19) infections and deaths?","volume":"114","author":"Aydemir","year":"2020","journal-title":"Pathog. Glob. Health"},{"key":"10.1016\/j.phymed.2026.158711_bib0006","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1016\/j.immuni.2024.03.019","article-title":"Ironing out the role of ferroptosis in immunity","volume":"57","author":"Bell","year":"2024","journal-title":"Immunity"},{"key":"10.1016\/j.phymed.2026.158711_bib0007","doi-asserted-by":"crossref","first-page":"20723","DOI":"10.1021\/acs.jmedchem.4c02736","article-title":"Natural products driven medicinal chemistry","volume":"67","author":"Bharate","year":"2024","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.phymed.2026.158711_bib0008","doi-asserted-by":"crossref","DOI":"10.1155\/2016\/5698931","article-title":"Does the interdependence between oxidative stress and inflammation explain the antioxidant paradox?","volume":"2016","author":"Biswas","year":"2016","journal-title":"Oxid. Med. Cell Longev."},{"key":"10.1016\/j.phymed.2026.158711_bib0009","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1038\/ni1001-907","article-title":"Nitric oxide and the immune response","volume":"2","author":"Bogdan","year":"2001","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.phymed.2026.158711_bib0010","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1038\/s41422-025-01107-6","article-title":"Pyroptosis: molecular mechanisms and roles in disease","volume":"35","author":"Broz","year":"2025","journal-title":"Cell Res."},{"key":"10.1016\/j.phymed.2026.158711_bib0013","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1007\/s00011-020-01378-2","article-title":"Macrophage polarization and its role in the pathogenesis of acute lung injury\/acute respiratory distress syndrome","volume":"69","author":"Chen","year":"2020","journal-title":"Inflamm. Res."},{"key":"10.1016\/j.phymed.2026.158711_bib0011","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1038\/s41571-020-00462-0","article-title":"Broadening horizons: the role of ferroptosis in cancer","volume":"18","author":"Chen","year":"2021","journal-title":"Nat. Rev. Clin. Oncol."},{"key":"10.1016\/j.phymed.2026.158711_bib0012","doi-asserted-by":"crossref","first-page":"2054","DOI":"10.1080\/15548627.2020.1810918","article-title":"Ferroptosis: machinery and regulation","volume":"17","author":"Chen","year":"2021","journal-title":"Autophagy"},{"key":"10.1016\/j.phymed.2026.158711_bib0014","doi-asserted-by":"crossref","first-page":"5879","DOI":"10.1038\/s41467-024-49629-8","article-title":"Asymmetric total synthesis of polycyclic xanthenes and discovery of a WalK activator active against MRSA","volume":"15","author":"Cheng","year":"2024","journal-title":"Nat. Commun."},{"key":"10.1016\/j.phymed.2026.158711_bib0015","doi-asserted-by":"crossref","DOI":"10.1002\/cpz1.210","article-title":"Measurement of cell death in mammalian cells","volume":"1","author":"Cummings","year":"2021","journal-title":"Curr. Protoc."},{"key":"10.1016\/j.phymed.2026.158711_bib0016","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.freeradbiomed.2025.06.002","article-title":"Glucose-6-phosphate dehydrogenase (G6PD) shields pancreatic cancer from autophagy-dependent ferroptosis by suppressing redox imbalance induced AMPK\/mTOR signaling","volume":"237","author":"Deepak","year":"2025","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.phymed.2026.158711_bib0017","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.arcmed.2011.01.003","article-title":"Glucose-6-phosphate-dehydrogenase deficiency may impart susceptibility to the development of AIDS","volume":"42","author":"Feily","year":"2011","journal-title":"Arch. Med. Res."},{"key":"10.1016\/j.phymed.2026.158711_bib0018","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1016\/j.tips.2021.07.002","article-title":"Treatment strategies for glucose-6-phosphate dehydrogenase deficiency: past and future perspectives","volume":"42","author":"Garcia","year":"2021","journal-title":"Trends. Pharmacol. Sci."},{"key":"10.1016\/j.phymed.2026.158711_bib0019","unstructured":"Global Tuberculosis Report 2024 [WWW Document], 2025. URL https:\/\/www.who.int\/publications\/i\/item\/9789240101531 (Accessed 9 April 2025)."},{"key":"10.1016\/j.phymed.2026.158711_bib0020","doi-asserted-by":"crossref","first-page":"1294","DOI":"10.15252\/emmm.201607315","article-title":"MG132-induced progerin clearance is mediated by autophagy activation and splicing regulation","volume":"9","author":"Harhouri","year":"2017","journal-title":"EMBo Mol. Med."},{"key":"10.1016\/j.phymed.2026.158711_bib0021","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1038\/s41580-020-00324-8","article-title":"Ferroptosis: mechanisms, biology and role in disease","volume":"22","author":"Jiang","year":"2021","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.phymed.2026.158711_bib0022","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1093\/ndt\/gfk047","article-title":"Macrophages contribute to the initiation of ischaemic acute renal failure in rats","volume":"21","author":"Jo","year":"2006","journal-title":"Nephrol. Dial. TransPlant"},{"key":"10.1016\/j.phymed.2026.158711_bib0023","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1186\/s12916-017-0930-5","article-title":"Macrophage activation-like syndrome: an immunological entity associated with rapid progression to death in sepsis","volume":"15","author":"Kyriazopoulou","year":"2017","journal-title":"BMC. Med."},{"key":"10.1016\/j.phymed.2026.158711_bib0024","doi-asserted-by":"crossref","first-page":"3611","DOI":"10.1111\/cas.13788","article-title":"Resibufogenin suppresses transforming growth factor-\u03b2-activated kinase 1-mediated nuclear factor-\u03bab activity through protein kinase C-dependent inhibition of glycogen synthase kinase 3","volume":"109","author":"Liu","year":"2018","journal-title":"Cancer Sci."},{"key":"10.1016\/j.phymed.2026.158711_bib0025","first-page":"195","article-title":"Progress in approved drugs from natural product resources","volume":"22","author":"Luo","year":"2024","journal-title":"Chin. J. Nat. Med."},{"key":"10.1016\/j.phymed.2026.158711_bib0026","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1021\/acs.jnatprod.9b01285","article-title":"Natural products as sources of new drugs over the nearly four decades from 01\/1981 to 09\/2019","volume":"83","author":"Newman","year":"2020","journal-title":"J. Nat. Prod."},{"key":"10.1016\/j.phymed.2026.158711_bib0027","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1016\/j.it.2021.04.007","article-title":"Tissue-resident macrophages: guardians of organ homeostasis","volume":"42","author":"Nobs","year":"2021","journal-title":"Trends. Immunol."},{"key":"10.1016\/j.phymed.2026.158711_bib0028","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1038\/nchembio.2229","article-title":"DPP8 and DPP9 inhibition induces pro-caspase-1-dependent monocyte and macrophage pyroptosis","volume":"13","author":"Okondo","year":"2017","journal-title":"Nat. Chem. Biol."},{"key":"10.1016\/j.phymed.2026.158711_bib0029","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1016\/j.jhep.2014.03.031","article-title":"Modulation of monocyte\/macrophage function: a therapeutic strategy in the treatment of acute liver failure","volume":"61","author":"Possamai","year":"2014","journal-title":"J. Hepatol."},{"key":"10.1016\/j.phymed.2026.158711_bib0030","doi-asserted-by":"crossref","first-page":"1430","DOI":"10.1038\/s41467-023-37148-x","article-title":"A mycobacterial effector promotes ferroptosis-dependent pathogenicity and dissemination","volume":"14","author":"Qiang","year":"2023","journal-title":"Nat. Commun."},{"key":"10.1016\/j.phymed.2026.158711_bib0031","doi-asserted-by":"crossref","first-page":"839","DOI":"10.3390\/pathogens12060839","article-title":"Virulence factors of mycobacterium tuberculosis as modulators of cell death mechanisms","volume":"12","author":"Ramon-Luing","year":"2023","journal-title":"Pathogens"},{"key":"10.1016\/j.phymed.2026.158711_bib0032","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.1002\/cmdc.201900341","article-title":"Small-molecule activators of glucose-6-phosphate dehydrogenase (G6PD) bridging the dimer interface","volume":"14","author":"Raub","year":"2019","journal-title":"Chem. Med. Chem."},{"key":"10.1016\/j.phymed.2026.158711_bib0033","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1016\/j.cellsig.2012.01.008","article-title":"Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling","volume":"24","author":"Ray","year":"2012","journal-title":"Cell Signal."},{"key":"10.1016\/j.phymed.2026.158711_bib0034","doi-asserted-by":"crossref","first-page":"449","DOI":"10.3390\/ijms24010449","article-title":"Lipid peroxidation and iron metabolism: two corner stones in the homeostasis control of ferroptosis","volume":"24","author":"Rochette","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.phymed.2026.158711_bib0035","doi-asserted-by":"crossref","first-page":"6425","DOI":"10.1002\/jcp.26429","article-title":"Macrophage plasticity, polarization, and function in health and disease","volume":"233","author":"Shapouri-Moghaddam","year":"2018","journal-title":"J. Cell Physiol."},{"key":"10.1016\/j.phymed.2026.158711_bib0036","doi-asserted-by":"crossref","first-page":"4443","DOI":"10.1016\/j.apsb.2024.04.031","article-title":"Targeted isolation of antiviral cinnamoylphloroglucinol-terpene adducts from Cleistocalyx operculatus by building blocks-based molecular networking approach","volume":"14","author":"Song","year":"2024","journal-title":"Acta Pharm. Sin. B"},{"key":"10.1016\/j.phymed.2026.158711_bib0038","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/j.cell.2017.09.021","article-title":"Ferroptosis: a regulated cell death nexus linking metabolism, redox biology, and disease","volume":"171","author":"Stockwell","year":"2017","journal-title":"Cell"},{"key":"10.1016\/j.phymed.2026.158711_bib0037","doi-asserted-by":"crossref","first-page":"2401","DOI":"10.1016\/j.cell.2022.06.003","article-title":"Ferroptosis turns 10: emerging mechanisms, physiological functions, and therapeutic applications","volume":"185","author":"Stockwell","year":"2022","journal-title":"Cell"},{"key":"10.1016\/j.phymed.2026.158711_bib0039","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1080\/15548627.2022.2084862","article-title":"Mitochondria ROS and mitophagy in acute kidney injury","volume":"19","author":"Su","year":"2023","journal-title":"Autophagy"},{"key":"10.1016\/j.phymed.2026.158711_bib0040","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.1038\/s41419-021-04306-2","article-title":"Fin56-induced ferroptosis is supported by autophagy-mediated GPX4 degradation and functions synergistically with mTOR inhibition to kill bladder cancer cells","volume":"12","author":"Sun","year":"2021","journal-title":"Cell Death. Dis."},{"key":"10.1016\/j.phymed.2026.158711_bib0041","doi-asserted-by":"crossref","first-page":"e183","DOI":"10.1016\/S1473-3099(18)30110-5","article-title":"Tuberculosis: progress and advances in development of new drugs, treatment regimens, and host-directed therapies","volume":"18","author":"Tiberi","year":"2018","journal-title":"Lancet Infect. Dis."},{"key":"10.1016\/j.phymed.2026.158711_bib0042","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.mehy.2015.05.006","article-title":"Glucose-6-phosphate dehydrogenase deficiency and Alzheimer\u2019s disease: partners in crime? The hypothesis","volume":"85","author":"Ulusu","year":"2015","journal-title":"Med. Hypotheses."},{"key":"10.1016\/j.phymed.2026.158711_bib0043","article-title":"Biomimetic synthesis of an antiviral cinnamoylphloroglucinol collection from Cleistocalyx operculatus: a synthetic strategy based on biogenetic building blocks","volume":"62","author":"Wang","year":"2023","journal-title":"Angew. Chem. Int. Ed. Engl."},{"key":"10.1016\/j.phymed.2026.158711_bib0044","doi-asserted-by":"crossref","first-page":"12544","DOI":"10.1021\/acs.jmedchem.5c00256","article-title":"Discovery of phloroglucinol derivatives as a new type of nonnucleoside inhibitors with anti-herpes simplex virus type 1 activity","volume":"68","author":"Wang","year":"2025","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.phymed.2026.158711_bib0045","doi-asserted-by":"crossref","first-page":"2619","DOI":"10.1172\/JCI124615","article-title":"The role of macrophages in the resolution of inflammation","volume":"129","author":"Watanabe","year":"2019","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.phymed.2026.158711_bib0046","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2119695119","article-title":"Allosteric role of a structural NADP+ molecule in glucose-6-phosphate dehydrogenase activity","volume":"119","author":"Wei","year":"2022","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.phymed.2026.158711_bib0047","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2023.110291","article-title":"Cisatracurium besylate rescues mycobacterium tuberculosis-infected macrophages from necroptosis and enhances the bactericidal effect of isoniazid","volume":"120","author":"Wen","year":"2023","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.phymed.2026.158711_bib0048","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1038\/nature09973","article-title":"TLR signalling augments macrophage bactericidal activity through mitochondrial ROS","volume":"472","author":"West","year":"2011","journal-title":"Nature"},{"key":"10.1016\/j.phymed.2026.158711_bib0049","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1038\/cdd.2015.158","article-title":"Ferroptosis: process and function","volume":"23","author":"Xie","year":"2016","journal-title":"Cell Death. Differ."},{"key":"10.1016\/j.phymed.2026.158711_bib0050","doi-asserted-by":"crossref","first-page":"3913","DOI":"10.7150\/jca.93208","article-title":"TXNDC12 inhibits pancreatic tumor cells ferroptosis by regulating GSH\/GGT7 and promotes its growth and metastasis","volume":"15","author":"Xu","year":"2024","journal-title":"J. Cancer"},{"key":"10.1016\/j.phymed.2026.158711_bib0051","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1038\/nature05859","article-title":"RAS-RAF-MEK-dependent oxidative cell death involving voltage-dependent anion channels","volume":"447","author":"Yagoda","year":"2007","journal-title":"Nature"},{"key":"10.1016\/j.phymed.2026.158711_bib0052","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1038\/s41419-022-04775-z","article-title":"Interaction between macrophages and ferroptosis","volume":"13","author":"Yang","year":"2022","journal-title":"Cell Death. Dis."}],"container-title":["Phytomedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0944711326009426?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0944711326009426?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T13:05:22Z","timestamp":1793192722000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0944711326009426"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,11]]},"references-count":52,"alternative-id":["S0944711326009426"],"URL":"https:\/\/doi.org\/10.1016\/j.phymed.2026.158711","relation":{},"ISSN":["0944-7113"],"issn-type":[{"value":"0944-7113","type":"print"}],"subject":[],"published":{"date-parts":[[2026,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A novel natural compound from Cleistocalyx operculatus enhances the anti-mycobacterial response by inhibiting ferroptosis","name":"articletitle","label":"Article Title"},{"value":"Phytomedicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.phymed.2026.158711","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier GmbH. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"158711"}}