{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T22:38:36Z","timestamp":1790980716197,"version":"4.1.0"},"reference-count":20,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2004,2,1]],"date-time":"2004-02-01T00:00:00Z","timestamp":1075593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2004,2,1]],"date-time":"2004-02-01T00:00:00Z","timestamp":1075593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Physiology &amp; Behavior"],"published-print":{"date-parts":[[2004,2]]},"DOI":"10.1016\/j.physbeh.2003.11.005","type":"journal-article","created":{"date-parts":[[2004,1,27]],"date-time":"2004-01-27T05:23:12Z","timestamp":1075180992000},"page":"665-668","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":28,"title":["Effect of acute stress and gender on isatin in rat tissues and serum"],"prefix":"10.1016","volume":"80","author":[{"given":"Natalia","family":"Igosheva","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon","family":"Matta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vivette","family":"Glover","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.physbeh.2003.11.005_BIB1","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1111\/j.1471-4159.1988.tb01089.x","article-title":"Isatin: identity with the purified monoamine oxidase inhibitor tribulin","volume":"51","author":"Glover","year":"1988","journal-title":"J. Neurochem."},{"key":"10.1016\/j.physbeh.2003.11.005_BIB2","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/0197-0186(90)90154-L","article-title":"Isatin, regional distribution in rat brain and tissues","volume":"17","author":"Watkins","year":"1990","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.physbeh.2003.11.005_BIB3","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1046\/j.1471-4159.2003.01564.x","article-title":"In situ imaging of specific binding of 3H-isatin in rat brain","volume":"84","author":"Crumeyrolle-Arias","year":"2003","journal-title":"J. Neurochem."},{"key":"10.1016\/j.physbeh.2003.11.005_BIB4","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1016\/0006-2952(80)90534-1","article-title":"A monoamine oxidase inhibitor in human urine","volume":"29","author":"Glover","year":"1980","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.physbeh.2003.11.005_BIB5","doi-asserted-by":"crossref","first-page":"2073","DOI":"10.1016\/0024-3205(95)02189-P","article-title":"Isatin is a potent endogenous antagonist of guanylate cyclase-coupled atrial natriuretic peptide receptors","volume":"57","author":"Glover","year":"1995","journal-title":"Life Sci."},{"key":"10.1016\/j.physbeh.2003.11.005_BIB6","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/0006-2952(96)00206-7","article-title":"Isatin: a link between natriuretic peptides and monoamines?","volume":"52","author":"Medvedev","year":"1996","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.physbeh.2003.11.005_BIB7","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1016\/S0006-2952(01)00809-7","article-title":"Effect of isatin on nitric oxide-stimulated soluble guanylate cyclase from human platelets","volume":"63","author":"Medvedev","year":"2002","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.physbeh.2003.11.005_BIB8","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1177\/026988119100500304","article-title":"Anxiogenic activity of isatin, a putative biological factor in rodents","volume":"5","author":"Bhattacharya","year":"1991","journal-title":"J. Psychopharmacol."},{"key":"10.1016\/j.physbeh.2003.11.005_BIB9","first-page":"23","article-title":"Isatin inhibits food intake in mice","volume":"305","author":"Morley","year":"1996","journal-title":"J. Pharmacol."},{"key":"10.1016\/j.physbeh.2003.11.005_BIB10","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1002\/(SICI)1099-1700(1998100)14:4<225::AID-SMI801>3.0.CO;2-P","article-title":"The psychopharmacology of isatin: a brief review","volume":"14","author":"Glover","year":"1998","journal-title":"Stress Med."},{"key":"10.1016\/j.physbeh.2003.11.005_BIB11","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1016\/S0006-2952(98)00199-3","article-title":"Stress-induced increase in urinary isatin excretion in rats reversal by both dexamethasone and alpha-methyl-p-tyrosine","volume":"56","author":"Tozawa","year":"1998","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.physbeh.2003.11.005_BIB12","first-page":"353","article-title":"Sex differences in adrenocortical sensitivity and resistance to cerebrovascular damage in rats under strong stress","volume":"114","author":"Anishchenko","year":"1992","journal-title":"Bull. Eksp. Biol Med."},{"key":"10.1016\/j.physbeh.2003.11.005_BIB13","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1159\/000054555","article-title":"Contribution of sex and cellular context in the regulation of brain corticosteroid receptors following restraint stress","volume":"71","author":"Karandera","year":"2002","journal-title":"Neuroendocrinology"},{"key":"10.1016\/j.physbeh.2003.11.005_BIB14","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1055\/s-2007-1004926","article-title":"Sex differences in adrenocortical structure and function: XXVIII. ACTH and corticosterone in intact, gonadoectomised and gonadal hormone replaced rats","volume":"22","author":"Lesniewska","year":"1990","journal-title":"Horm. Metab. Res."},{"key":"10.1016\/j.physbeh.2003.11.005_BIB15","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/S0024-3205(98)00243-4","article-title":"Comparison of the neuroendocrine responses to stress in outbred, inbred and F hybrid rats","volume":"63","author":"Sarrieau","year":"1998","journal-title":"Life Sci."},{"key":"10.1016\/j.physbeh.2003.11.005_BIB16","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1111\/j.1749-6632.1995.tb44675.x","article-title":"Effects of various stressors on in vivo norepinephrine release in the hypothalamic paraventricular nucleus and on the pituitary\u2013adrenocortical axis","volume":"771","author":"Pacak","year":"1995","journal-title":"Ann. N.Y. Acad. Sci."},{"key":"10.1016\/j.physbeh.2003.11.005_BIB17","doi-asserted-by":"crossref","first-page":"2503","DOI":"10.1210\/endo-129-5-2503","article-title":"Variations in the hypothalamic\u2013pituitary\u2013adrenal response to stress during the estrous cycle in the rat","volume":"129","author":"Viau","year":"1991","journal-title":"Endocrinology"},{"key":"10.1016\/j.physbeh.2003.11.005_BIB18","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/S0014-2999(02)01310-9","article-title":"Peripheral 5-HT2A-receptor-mediated formation of an inhibitor of atrial natriuretic peptide binding involves inflammation","volume":"440","author":"Tozawa","year":"2002","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.physbeh.2003.11.005_BIB19","doi-asserted-by":"crossref","first-page":"1074","DOI":"10.1111\/j.1471-4159.1991.tb08259.x","article-title":"Urinary but not brain isatin levels are reduced in germ-free rats","volume":"57","author":"Sandler","year":"1991","journal-title":"J. Neurochem."},{"key":"10.1016\/j.physbeh.2003.11.005_BIB20","series-title":"Phylogeny and development of catecholamine systems in the CNS of vertebrates","first-page":"453","article-title":"Sexual differentiation of central catecholamine systems","author":"Reisert","year":"1990"}],"container-title":["Physiology &amp; Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0031938403003366?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0031938403003366?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T17:53:59Z","timestamp":1758477239000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0031938403003366"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,2]]},"references-count":20,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2004,2]]}},"alternative-id":["S0031938403003366"],"URL":"https:\/\/doi.org\/10.1016\/j.physbeh.2003.11.005","relation":{},"ISSN":["0031-9384"],"issn-type":[{"value":"0031-9384","type":"print"}],"subject":[],"published":{"date-parts":[[2004,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effect of acute stress and gender on isatin in rat tissues and serum","name":"articletitle","label":"Article Title"},{"value":"Physiology & Behavior","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.physbeh.2003.11.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"converted-article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2004 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}