{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T19:15:20Z","timestamp":1790018120356,"version":"4.0.1"},"reference-count":77,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2011,8,1]],"date-time":"2011-08-01T00:00:00Z","timestamp":1312156800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Physiology & Behavior"],"published-print":{"date-parts":[[2011,8]]},"DOI":"10.1016\/j.physbeh.2010.11.015","type":"journal-article","created":{"date-parts":[[2010,11,17]],"date-time":"2010-11-17T09:20:34Z","timestamp":1289985634000},"page":"205-214","source":"Crossref","is-referenced-by-count":33,"title":["Disruption of the neuregulin 1 gene in the rat alters HPA axis activity and behavioral responses to environmental stimuli"],"prefix":"10.1016","volume":"104","author":[{"given":"S.B.","family":"Taylor","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.R.","family":"Taylor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.A.","family":"Markham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.M.","family":"Geurts","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.Z.","family":"Kanaskie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.I.","family":"Koenig","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.physbeh.2010.11.015_bb0005","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1146\/annurev.clinpsy.4.022007.141248","article-title":"Stress and the hypothalamic pituitary adrenal axis in the developmental course of schizophrenia","volume":"4","author":"Walker","year":"2008","journal-title":"Annu. Rev. Clin. Psychol."},{"key":"10.1016\/j.physbeh.2010.11.015_bb0010","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1176\/ajp.156.6.837","article-title":"Causal relationship between stressful life events and the onset of major depression","volume":"156","author":"Kendler","year":"1999","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.physbeh.2010.11.015_bb0015","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1521\/jscp.2007.26.4.460","article-title":"Childhood stressful life events and bipolar spectrum disorders","volume":"26","author":"Grandin","year":"2007","journal-title":"J. Soc. Clin. Psychol."},{"key":"10.1016\/j.physbeh.2010.11.015_bb0020","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.neuron.2007.09.006","article-title":"Response variation following trauma: a translational neuroscience approach to understanding PTSD","volume":"56","author":"Yehuda","year":"2007","journal-title":"Neuron"},{"key":"10.1016\/j.physbeh.2010.11.015_bb0025","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/S0893-133X(01)00396-7","article-title":"Glucocorticoid hormones and early brain development in schizophrenia","volume":"27","author":"Koenig","year":"2002","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.physbeh.2010.11.015_bb0030","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1210\/er.19.3.269","article-title":"Brain corticosteroid receptor balance in health and disease","volume":"19","author":"de Kloet","year":"1998","journal-title":"Endocr. Rev."},{"key":"10.1016\/j.physbeh.2010.11.015_bb0035","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/0306-4530(87)90040-0","article-title":"Feedback action and tonic influence of corticosteroids on brain function: a concept arising from the heterogeneity of brain receptor systems","volume":"12","author":"de Kloet","year":"1987","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.physbeh.2010.11.015_bb0040","doi-asserted-by":"crossref","first-page":"1971","DOI":"10.1523\/JNEUROSCI.2173-05.2006","article-title":"Forebrain glucocorticoid receptors modulate anxiety-associated locomotor activation and adrenal responsiveness","volume":"26","author":"Boyle","year":"2006","journal-title":"J. Neurosci."},{"key":"10.1016\/j.physbeh.2010.11.015_bb0045","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.brainres.2009.03.061","article-title":"Defining brain region-specific glucocorticoid action during stress by conditional gene disruption in mice","volume":"1293","author":"Kolber","year":"2009","journal-title":"Brain Res."},{"key":"10.1016\/j.physbeh.2010.11.015_bb0050","doi-asserted-by":"crossref","first-page":"12004","DOI":"10.1073\/pnas.0803216105","article-title":"Central amygdala glucocorticoid receptor action promotes fear-associated CRH activation and conditioning","volume":"105","author":"Kolber","year":"2008","journal-title":"Proc. Natl Acad. Sci. USA"},{"issue":"Suppl 1","key":"10.1016\/j.physbeh.2010.11.015_bb0055","doi-asserted-by":"crossref","first-page":"S87","DOI":"10.1016\/S0306-4530(97)00020-6","article-title":"Behavioral and neuroendocrine responses controlled by the concerted action of central mineralocorticoid (MRS) and glucocorticoid receptors (GRS)","volume":"22","author":"Oitzl","year":"1997","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.physbeh.2010.11.015_bb0060","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1267\/ahc.08013","article-title":"Expressions of hippocampal mineralocorticoid receptor (MR) and glucocorticoid receptor (GR) in the single-prolonged stress-rats","volume":"41","author":"Zhe","year":"2008","journal-title":"Acta Histochem. Cytochem."},{"key":"10.1016\/j.physbeh.2010.11.015_bb0065","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1086\/342734","article-title":"Neuregulin 1 and susceptibility to schizophrenia","volume":"71","author":"Stefansson","year":"2002","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.physbeh.2010.11.015_bb0070","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1086\/345442","article-title":"Association of neuregulin 1 with schizophrenia confirmed in a Scottish population","volume":"72","author":"Stefansson","year":"2003","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.physbeh.2010.11.015_bb0075","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.biopsych.2005.11.002","article-title":"Neuregulin 1 and schizophrenia: genetics, gene expression, and neurobiology","volume":"60","author":"Harrison","year":"2006","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.physbeh.2010.11.015_bb0080","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1097\/YPG.0b013e32832a4f69","article-title":"An association study of the neuregulin 1 gene, bipolar affective disorder and psychosis","volume":"19","author":"Prata","year":"2009","journal-title":"Psychiatr. Genet."},{"key":"10.1016\/j.physbeh.2010.11.015_bb0085","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/S0014-4827(02)00102-7","article-title":"Neuregulins: functions, forms, and signaling strategies","volume":"284","author":"Falls","year":"2003","journal-title":"Exp. Cell Res."},{"key":"10.1016\/j.physbeh.2010.11.015_bb0090","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.brainresrev.2005.11.006","article-title":"Neuregulins: versatile growth and differentiation factors in nervous system development and human disease","volume":"51","author":"Esper","year":"2006","journal-title":"Brain Res. Rev."},{"key":"10.1016\/j.physbeh.2010.11.015_bb0095","doi-asserted-by":"crossref","first-page":"24343","DOI":"10.1074\/jbc.M702953200","article-title":"Molecular cloning of a brain-specific, developmentally regulated neuregulin 1 (NRG1) isoform and identification of a functional promoter variant associated with schizophrenia","volume":"282","author":"Tan","year":"2007","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.physbeh.2010.11.015_bb0100","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.1111\/j.1471-4159.2010.06677.x","article-title":"Molecular and cellular characterization of Neuregulin-1 type IV isoforms","volume":"113","author":"Shamir","year":"2010","journal-title":"J. Neurochem."},{"key":"10.1016\/j.physbeh.2010.11.015_bb0105","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.gene.2004.07.029","article-title":"Multiple novel transcription initiation sites for NRG1","volume":"342","author":"Steinthorsdottir","year":"2004","journal-title":"Gene"},{"key":"10.1016\/j.physbeh.2010.11.015_bb0110","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1038\/nrn2392","article-title":"Neuregulin 1 in neural development, synaptic plasticity and schizophrenia","volume":"9","author":"Mei","year":"2008","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.physbeh.2010.11.015_bb0115","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/j.schres.2007.10.013","article-title":"Increased levels of serotonin 2A receptors and serotonin transporter in the CNS of neuregulin 1 hypomorphic\/mutant mice","volume":"99","author":"Dean","year":"2008","journal-title":"Schizophr. Res."},{"key":"10.1016\/j.physbeh.2010.11.015_bb0120","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1523\/JNEUROSCI.23-01-00230.2003","article-title":"Normal female sexual development requires neuregulin-erbB receptor signaling in hypothalamic astrocytes","volume":"23","author":"Prevot","year":"2003","journal-title":"J. Neurosci."},{"key":"10.1016\/j.physbeh.2010.11.015_bb0125","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1002\/cne.903490306","article-title":"Expression of multiple neuregulin transcripts in postnatal rat brains","volume":"349","author":"Chen","year":"1994","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.physbeh.2010.11.015_bb0130","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1002\/cne.1127","article-title":"ErbB transmembrane tyrosine kinase receptors are differentially expressed throughout the adult rat central nervous system","volume":"433","author":"Gerecke","year":"2001","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.physbeh.2010.11.015_bb0135","doi-asserted-by":"crossref","first-page":"9913","DOI":"10.1523\/JNEUROSCI.19-22-09913.1999","article-title":"Neuregulins signaling via a glial erbB-2\u2013erbB-4 receptor complex contribute to the neuroendocrine control of mammalian sexual development","volume":"19","author":"Ma","year":"1999","journal-title":"J. Neurosci."},{"key":"10.1016\/j.physbeh.2010.11.015_bb0140","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1002\/ajmg.b.30812","article-title":"A polymorphism of the neuregulin 1 gene (SNP8NRG243177\/rs6994992) affects reactivity to expressed emotion in schizophrenia","volume":"150B","author":"Keri","year":"2009","journal-title":"Am. J. Med. Genet. B Neuropsychiatr. Genet."},{"key":"10.1016\/j.physbeh.2010.11.015_bb0145","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1007\/BF02879896","article-title":"Neuregulin-1 genotype moderates the association between job strain and early atherosclerosis in young men","volume":"33","author":"Hintsanen","year":"2007","journal-title":"Ann. Behav. Med."},{"key":"10.1016\/j.physbeh.2010.11.015_bb0150","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1007\/s00335-007-9025-5","article-title":"Generation of rat mutants using a coat color-tagged Sleeping Beauty transposon system","volume":"18","author":"Lu","year":"2007","journal-title":"Mamm. Genome"},{"key":"10.1016\/j.physbeh.2010.11.015_bb0155","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1080\/01677060802669766","article-title":"Survey of schizophrenia and bipolar disorder candidate genes using chromatin immunoprecipitation and tiled microarrays (ChIP-chip)","volume":"23","author":"Pedrosa","year":"2009","journal-title":"J. Neurogenet."},{"key":"10.1016\/j.physbeh.2010.11.015_bb0160","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/j.yhbeh.2007.03.017","article-title":"Evidence for the involvement of ERbeta and RGS9-2 in 17-beta estradiol enhancement of amphetamine-induced place preference behavior","volume":"52","author":"Silverman","year":"2007","journal-title":"Horm. Behav."},{"key":"10.1016\/j.physbeh.2010.11.015_bb0165","series-title":"The rat brain in stereotaxic coordinates","author":"Paxinos","year":"1986"},{"key":"10.1016\/j.physbeh.2010.11.015_bb0170","doi-asserted-by":"crossref","DOI":"10.1002\/0471142301.ns0815s17","article-title":"Parental behaviors in rats and mice","author":"Lonstein","year":"2002","journal-title":"Curr. Protoc. Neurosci."},{"key":"10.1016\/j.physbeh.2010.11.015_bb0175","doi-asserted-by":"crossref","first-page":"E823","DOI":"10.1152\/ajpendo.00122.2005","article-title":"Comparative analysis of ACTH and corticosterone sampling methods in rats","volume":"289","author":"Vahl","year":"2005","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"key":"10.1016\/j.physbeh.2010.11.015_bb0180","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/j.bbr.2004.05.030","article-title":"Prenatal exposure to a repeated variable stress paradigm elicits behavioral and neuroendocrinological changes in the adult offspring: potential relevance to schizophrenia","volume":"156","author":"Koenig","year":"2005","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.physbeh.2010.11.015_bb0185","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1023\/B:NEUR.0000020614.83883.be","article-title":"Neuregulins and the neuromuscular system: 10years of answers and questions","volume":"32","author":"Falls","year":"2003","journal-title":"J. Neurocytol."},{"key":"10.1016\/j.physbeh.2010.11.015_bb0190","doi-asserted-by":"crossref","first-page":"1659","DOI":"10.1126\/science.277.5332.1659","article-title":"Maternal care, hippocampal glucocorticoid receptors, and hypothalamic\u2013pituitary\u2013adrenal responses to stress","volume":"277","author":"Liu","year":"1997","journal-title":"Science"},{"key":"10.1016\/j.physbeh.2010.11.015_bb0195","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1111\/j.1749-6632.1994.tb39245.x","article-title":"The ontogeny of the hypothalamic\u2013pituitary\u2013adrenal axis. The influence of maternal factors","volume":"746","author":"Levine","year":"1994","journal-title":"Ann. NY Acad. Sci."},{"key":"10.1016\/j.physbeh.2010.11.015_bb0200","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/0169-328X(93)90189-V","article-title":"Early, postnatal experience alters hypothalamic corticotropin-releasing factor (CRF) mRNA, median eminence CRF content and stress-induced release in adult rats","volume":"18","author":"Plotsky","year":"1993","journal-title":"Brain Res. Mol. Brain Res."},{"key":"10.1016\/j.physbeh.2010.11.015_bb0205","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.neuroscience.2007.03.051","article-title":"Phenotypic characterization of spatial cognition and social behavior in mice with \u2018knockout\u2019 of the schizophrenia risk gene neuregulin 1","volume":"147","author":"O'Tuathaigh","year":"2007","journal-title":"Neuroscience"},{"key":"10.1016\/j.physbeh.2010.11.015_bb0210","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1111\/j.1601-183X.2006.00298.x","article-title":"Altered motor activity, exploration and anxiety in heterozygous neuregulin 1 mutant mice: implications for understanding schizophrenia","volume":"6","author":"Karl","year":"2007","journal-title":"Genes Brain Behav."},{"key":"10.1016\/j.physbeh.2010.11.015_bb0215","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1007\/s00213-007-0721-3","article-title":"Heterozygous neuregulin 1 mice are more sensitive to the behavioural effects of Delta9-tetrahydrocannabinol","volume":"192","author":"Boucher","year":"2007","journal-title":"Psychopharmacology (Berl.)"},{"key":"10.1016\/j.physbeh.2010.11.015_bb0220","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/S0166-4328(99)00175-8","article-title":"Heregulin, but not ErbB2 or ErbB3, heterozygous mutant mice exhibit hyperactivity in multiple behavioral tasks","volume":"109","author":"Gerlai","year":"2000","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.physbeh.2010.11.015_bb0225","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1097\/00001756-200502280-00014","article-title":"Neuregulin-1 immunoglobulin-like domain mutant mice: clozapine sensitivity and impaired latent inhibition","volume":"16","author":"Rimer","year":"2005","journal-title":"NeuroReport"},{"key":"10.1016\/j.physbeh.2010.11.015_bb0230","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1038\/sj.mp.4001434","article-title":"Expression analysis of neuregulin-1 in the dorsolateral prefrontal cortex in schizophrenia","volume":"9","author":"Hashimoto","year":"2004","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.physbeh.2010.11.015_bb0235","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.yfrne.2003.07.001","article-title":"Central mechanisms of stress integration: hierarchical circuitry controlling hypothalamo\u2013pituitary\u2013adrenocortical responsiveness","volume":"24","author":"Herman","year":"2003","journal-title":"Front. Neuroendocrinol."},{"key":"10.1016\/j.physbeh.2010.11.015_bb0240","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/0006-8993(93)90196-T","article-title":"Stress response, adrenal steroid receptor levels and corticosteroid-binding globulin levels\u2014a comparison between Sprague\u2212Dawley, Fischer 344 and Lewis rats","volume":"616","author":"Dhabhar","year":"1993","journal-title":"Brain Res."},{"key":"10.1016\/j.physbeh.2010.11.015_bb0245","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/0165-5728(94)00135-B","article-title":"Differential activation of adrenal steroid receptors in neural and immune tissues of Sprague Dawley, Fischer 344, and Lewis rats","volume":"56","author":"Dhabhar","year":"1995","journal-title":"J. Neuroimmunol."},{"key":"10.1016\/j.physbeh.2010.11.015_bb0250","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1159\/000126298","article-title":"Differential startle amplitude and corticosterone response in rats","volume":"56","author":"Glowa","year":"1992","journal-title":"Neuroendocrinology"},{"key":"10.1016\/j.physbeh.2010.11.015_bb0255","doi-asserted-by":"crossref","first-page":"2718","DOI":"10.1210\/en.139.6.2718","article-title":"Evidence for mineralocorticoid receptor facilitation of glucocorticoid receptor-dependent regulation of hypothalamic\u2013pituitary\u2013adrenal axis activity","volume":"139","author":"Spencer","year":"1998","journal-title":"Endocrinology"},{"key":"10.1016\/j.physbeh.2010.11.015_bb0260","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1210\/edrv-12-2-118","article-title":"The role of the hippocampus in feedback regulation of the hypothalamic\u2013pituitary\u2013adrenocortical axis","volume":"12","author":"Jacobson","year":"1991","journal-title":"Endocr. Rev."},{"key":"10.1016\/j.physbeh.2010.11.015_bb0265","first-page":"95","article-title":"Brain corticosteroid receptor balance and homeostatic control","volume":"12","author":"de Kloet","year":"1991","journal-title":"Front. Neuroendocrinol."},{"key":"10.1016\/j.physbeh.2010.11.015_bb0270","doi-asserted-by":"crossref","first-page":"2250","DOI":"10.1111\/j.1460-9568.2008.06218.x","article-title":"Characterization of the vulnerability to repeated stress in Fischer 344 rats: possible involvement of microRNA-mediated down-regulation of the glucocorticoid receptor","volume":"27","author":"Uchida","year":"2008","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.physbeh.2010.11.015_bb0275","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1183\/09031936.06.00132305","article-title":"ErbB receptor regulation by dexamethasone in mouse type II epithelial cells","volume":"28","author":"Dammann","year":"2006","journal-title":"Eur. Respir. J."},{"key":"10.1016\/j.physbeh.2010.11.015_bb0280","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1037\/0735-7044.122.4.748","article-title":"Behavioral profile of a heterozygous mutant mouse model for EGF-like domain neuregulin 1","volume":"122","author":"Duffy","year":"2008","journal-title":"Behav. Neurosci."},{"key":"10.1016\/j.physbeh.2010.11.015_bb0285","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1097\/01.wnr.0000192738.31029.0a","article-title":"Sexually dimorphic changes in the exploratory and habituation profiles of heterozygous neuregulin-1 knockout mice","volume":"17","author":"O'Tuathaigh","year":"2006","journal-title":"NeuroReport"},{"key":"10.1016\/j.physbeh.2010.11.015_bb0290","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.bbr.2005.04.007","article-title":"Movements of exploration intact in rats with hippocampal lesions","volume":"163","author":"Clark","year":"2005","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.physbeh.2010.11.015_bb0295","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1176\/ajp.150.4.653","article-title":"Association of nonsuppression of cortisol on the DST with primary polydipsia in chronic schizophrenia","volume":"150","author":"Goldman","year":"1993","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.physbeh.2010.11.015_bb0300","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1016\/j.psyneuen.2003.08.011","article-title":"Evidence of basal pituitary\u2013adrenal overactivity in first episode, drug naive patients with schizophrenia","volume":"29","author":"Ryan","year":"2004","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.physbeh.2010.11.015_bb0305","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1016\/0006-3223(91)90353-N","article-title":"Dexamethasone suppression test in schizophrenia: relationship to symptomatology, ventricular enlargement, and outcome","volume":"29","author":"Tandon","year":"1991","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.physbeh.2010.11.015_bb0310","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.schres.2009.12.021","article-title":"Higher cortisol levels are associated with smaller left hippocampal volume in first-episode psychosis","volume":"119","author":"Mondelli","year":"2010","journal-title":"Schizophr. Res."},{"key":"10.1016\/j.physbeh.2010.11.015_bb0315","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1038\/nrn1683","article-title":"Stress and the brain: from adaptation to disease","volume":"6","author":"de Kloet","year":"2005","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.physbeh.2010.11.015_bb0320","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1001\/archpsyc.1991.01810320017003","article-title":"Loss of glucocorticoid fast feedback in depression","volume":"48","author":"Young","year":"1991","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.physbeh.2010.11.015_bb0325","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/S0893-133X(97)00144-9","article-title":"Hormonal response pattern in the combined DEX-CRH test is stable over time in subjects at high familial risk for affective disorders","volume":"18","author":"Modell","year":"1998","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.physbeh.2010.11.015_bb0330","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/j.biopsych.2005.04.018","article-title":"Pituitary volume predicts future transition to psychosis in individuals at ultra-high risk of developing psychosis","volume":"58","author":"Garner","year":"2005","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.physbeh.2010.11.015_bb0335","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1016\/j.biopsych.2006.08.043","article-title":"The relations among putative biorisk markers in schizotypal adolescents: minor physical anomalies, movement abnormalities, and salivary cortisol","volume":"61","author":"Mittal","year":"2007","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.physbeh.2010.11.015_bb0340","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1111\/j.1749-6632.2009.04978.x","article-title":"Risk factors for development of depression and psychosis. Glucocorticoid receptors and pituitary implications for treatment with antidepressant and glucocorticoids","volume":"1179","author":"Pariante","year":"2009","journal-title":"Ann. NY Acad. Sci."},{"key":"10.1016\/j.physbeh.2010.11.015_bb0345","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1111\/j.1749-6632.2009.04979.x","article-title":"Status of glucocorticoid alterations in post-traumatic stress disorder","volume":"1179","author":"Yehuda","year":"2009","journal-title":"Ann. NY Acad. Sci."},{"key":"10.1016\/j.physbeh.2010.11.015_bb0350","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1159\/000087097","article-title":"Chronic mild stress (CMS) revisited: consistency and behavioural\u2013neurobiological concordance in the effects of CMS","volume":"52","author":"Willner","year":"2005","journal-title":"Neuropsychobiology"},{"key":"10.1016\/j.physbeh.2010.11.015_bb0355","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1016\/j.yhbeh.2006.06.033","article-title":"Stress sensitivity and the development of affective disorders","volume":"50","author":"Bale","year":"2006","journal-title":"Horm. Behav."},{"key":"10.1016\/j.physbeh.2010.11.015_bb0360","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/j.brainres.2007.04.042","article-title":"Prenatal stress generates deficits in rat social behavior: reversal by oxytocin","volume":"1156","author":"Lee","year":"2007","journal-title":"Brain Res."},{"key":"10.1016\/j.physbeh.2010.11.015_bb0365","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/S0079-6123(07)67002-2","article-title":"Glucocorticoids, developmental \u2018programming\u2019 and the risk of affective dysfunction","volume":"167","author":"Seckl","year":"2008","journal-title":"Prog. Brain Res."},{"key":"10.1016\/j.physbeh.2010.11.015_bb0370","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.1093\/schbul\/sbn101","article-title":"Psychosocial stress and psychosis. A review of the neurobiological mechanisms and the evidence for gene\u2013stress interaction","volume":"34","author":"van Winkel","year":"2008","journal-title":"Schizophr. Bull."},{"key":"10.1016\/j.physbeh.2010.11.015_bb0375","doi-asserted-by":"crossref","first-page":"1110","DOI":"10.1002\/da.20629","article-title":"Single prolonged stress: toward an animal model of posttraumatic stress disorder","volume":"26","author":"Yamamoto","year":"2009","journal-title":"Depress. Anxiety"},{"key":"10.1016\/j.physbeh.2010.11.015_bb0380","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1196\/annals.1364.026","article-title":"The contribution of an animal model toward uncovering biological risk factors for PTSD","volume":"1071","author":"Cohen","year":"2006","journal-title":"Ann. NY Acad. Sci."},{"key":"10.1016\/j.physbeh.2010.11.015_bb0385","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1046\/j.1365-2826.1999.00288.x","article-title":"Differential regulation of hippocampal glucocorticoid receptors mRNA and fast feedback: relevance to post-traumatic stress disorder","volume":"11","author":"Liberzon","year":"1999","journal-title":"J. Neuroendocrinol."}],"container-title":["Physiology & Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0031938410004038?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0031938410004038?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T08:27:12Z","timestamp":1711960032000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0031938410004038"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,8]]},"references-count":77,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2011,8]]}},"alternative-id":["S0031938410004038"],"URL":"https:\/\/doi.org\/10.1016\/j.physbeh.2010.11.015","relation":{},"ISSN":["0031-9384"],"issn-type":[{"value":"0031-9384","type":"print"}],"subject":[],"published":{"date-parts":[[2011,8]]}}}