{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T22:48:03Z","timestamp":1769726883887,"version":"3.49.0"},"reference-count":30,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2014,6,1]],"date-time":"2014-06-01T00:00:00Z","timestamp":1401580800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,6,1]],"date-time":"2014-06-01T00:00:00Z","timestamp":1401580800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Physiology & Behavior"],"published-print":{"date-parts":[[2014,6]]},"DOI":"10.1016\/j.physbeh.2014.04.047","type":"journal-article","created":{"date-parts":[[2014,5,9]],"date-time":"2014-05-09T11:08:16Z","timestamp":1399633696000},"page":"66-72","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"special_numbering":"C","title":["The anorectic effects of alpha-lipoicacid are mediated by central AMPK and are not due to taste aversion in chicken (Gallus gallus)"],"prefix":"10.1016","volume":"132","author":[{"given":"Yufeng","family":"Wang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhigang","family":"Song","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nadia","family":"Everaert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bart","family":"De Ketelaere","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hilke","family":"Willemsen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eddy","family":"Decuypere","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johan","family":"Buyse","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.physbeh.2014.04.047_bb0005","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1152\/physrev.00011.2008","article-title":"AMPK in health and disease","volume":"89","author":"Steinberg","year":"2009","journal-title":"Physiol Rev"},{"key":"10.1016\/j.physbeh.2014.04.047_bb0010","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1038\/nature02440","article-title":"AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus","volume":"428","author":"Minokoshi","year":"2004","journal-title":"Nature"},{"key":"10.1016\/j.physbeh.2014.04.047_bb0015","doi-asserted-by":"crossref","first-page":"19970","DOI":"10.1074\/jbc.M402165200","article-title":"C75, a fatty acid synthase inhibitor, reduces food intake via hypothalamic AMP-activated protein kinase","volume":"279","author":"Kim","year":"2004","journal-title":"J Biol Chem"},{"key":"10.1016\/j.physbeh.2014.04.047_bb0020","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1113\/jphysiol.2006.113217","article-title":"AMPK integrates nutrient and hormonal signals to regulate food intake and energy balance through effects in the hypothalamus and peripheral tissues","volume":"574","author":"Xue","year":"2006","journal-title":"J Physiol"},{"key":"10.1016\/j.physbeh.2014.04.047_bb0025","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.cbpb.2005.10.009","article-title":"Characterization of the AMP-activated protein kinase pathway in chickens","volume":"143","author":"Proszkowiec-Weglarz","year":"2006","journal-title":"Comp Biochem Physiol B Biochem Mol Biol"},{"key":"10.1016\/j.physbeh.2014.04.047_bb0030","doi-asserted-by":"crossref","first-page":"159","DOI":"10.3382\/ps.2008-00262","article-title":"Expression and activity of the 5\u2032-adenosine monophosphate-activated protein kinase pathway in selected tissues during chicken embryonic development","volume":"88","author":"Proszkowiec-Weglarz","year":"2009","journal-title":"Poult Sci"},{"key":"10.1016\/j.physbeh.2014.04.047_bb0035","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1016\/j.ygcen.2012.06.026","article-title":"Fasting alters protein expression of AMP-activated protein kinase in the hypothalamus of broiler chicks (Gallus gallus domesticus)","volume":"178","author":"Song","year":"2012","journal-title":"Gen Comp Endocrinol"},{"key":"10.1016\/j.physbeh.2014.04.047_bb0040","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1038\/nm0704-681","article-title":"Cellular energy sensor balances the scales","volume":"10","author":"Small","year":"2004","journal-title":"Nat Med"},{"key":"10.1016\/j.physbeh.2014.04.047_bb0045","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1016\/j.amjmed.2010.08.005","article-title":"Effects of alpha-lipoic acid on body weight in obese subjects","volume":"124","author":"Koh","year":"2011","journal-title":"Am J Med"},{"key":"10.1016\/j.physbeh.2014.04.047_bb0050","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1038\/nm1061","article-title":"Anti-obesity effects of alpha-lipoic acid mediated by suppression of hypothalamic AMP-activated protein kinase","volume":"10","author":"Kim","year":"2004","journal-title":"Nat Med"},{"key":"10.1016\/j.physbeh.2014.04.047_bb0055","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.1097\/gme.0b013e31820db576","article-title":"Reciprocal effects of alpha-lipoic acid on adenosine monophosphate-activated protein kinase activity in obesity induced by ovariectomy in rats","volume":"18","author":"Cheng","year":"2011","journal-title":"Menopause"},{"key":"10.1016\/j.physbeh.2014.04.047_bb0060","doi-asserted-by":"crossref","first-page":"218","DOI":"10.3164\/jcbn.08-215","article-title":"The degradation and regeneration of alpha-lipoic acid under the irradiation of UV light in the existence of homocysteine","volume":"44","author":"Wada","year":"2009","journal-title":"J Clin Biochem Nutr"},{"key":"10.1016\/j.physbeh.2014.04.047_bb0065","series-title":"A stereotaxic atlas of the brain of the chick (Gallus domesticus)","author":"Kuenzel","year":"1988"},{"key":"10.1016\/j.physbeh.2014.04.047_bb0070","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1016\/j.cbpa.2012.08.009","article-title":"Chicken FTO gene: tissue-specific expression, brain distribution, breed difference and effect of fasting","volume":"163","author":"Wang","year":"2012","journal-title":"Comp Biochem Physiol A Mol Integr Physiol"},{"key":"10.1016\/j.physbeh.2014.04.047_bb0075","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2(\u2212delta delta C(T)) Method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"10.1016\/j.physbeh.2014.04.047_bb0080","doi-asserted-by":"crossref","first-page":"254","DOI":"10.2141\/jpsa.42.254","article-title":"Aversion to quinine is associated with taste sensation in chicks","volume":"42","author":"Ueda","year":"2005","journal-title":"J Poult Sci"},{"key":"10.1016\/j.physbeh.2014.04.047_bb0085","doi-asserted-by":"crossref","first-page":"2611","DOI":"10.2527\/2005.83112611x","article-title":"Effect of dietary alpha-lipoic acid on growth, body composition, muscle pH, and AMP-activated protein kinase phosphorylation in mice","volume":"83","author":"Shen","year":"2005","journal-title":"J Anim Sci"},{"key":"10.1016\/j.physbeh.2014.04.047_bb0090","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/S0091-6773(79)90171-8","article-title":"Food intake reduction: satiation or aversion?","volume":"24","author":"Deutsch","year":"1978","journal-title":"Behav Biol"},{"key":"10.1016\/j.physbeh.2014.04.047_bb0095","doi-asserted-by":"crossref","first-page":"1478","DOI":"10.1093\/ps\/86.7.1478","article-title":"Mechanisms regulating feed intake, energy expenditure, and body weight in poultry","volume":"86","author":"Richards","year":"2007","journal-title":"Poult Sci"},{"key":"10.1016\/j.physbeh.2014.04.047_bb0100","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.ygcen.2013.05.006","article-title":"The endocrine control of energy homeostasis in chickens","volume":"190","author":"Song","year":"2013","journal-title":"Gen Comp Endocrinol"},{"key":"10.1016\/j.physbeh.2014.04.047_bb0105","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1038\/1082","article-title":"Coexpression of AgRP and NPY in fasting-activated hypothalamic neurons","volume":"1","author":"Hahn","year":"1998","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.physbeh.2014.04.047_bb0110","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1677\/joe.1.06783","article-title":"The melanocortin circuit in obese and lean strains of chicks","volume":"190","author":"Hen","year":"2006","journal-title":"J Endocrinol"},{"key":"10.1016\/j.physbeh.2014.04.047_bb0115","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1158\/0008-5472.CAN-03-0145","article-title":"Nur77 activated by hypoxia-inducible factor-1alpha overproduces proopiomelanocortin in von Hippel-Lindau-mutated renal cell carcinoma","volume":"64","author":"Choi","year":"2004","journal-title":"Cancer Res"},{"key":"10.1016\/j.physbeh.2014.04.047_bb0120","doi-asserted-by":"crossref","first-page":"e1001112","DOI":"10.1371\/journal.pbio.1001112","article-title":"Hypoxia-inducible factor directs POMC gene to mediate hypothalamic glucose sensing and energy balance regulation","volume":"9","author":"Zhang","year":"2011","journal-title":"PLoS Biol"},{"key":"10.1016\/j.physbeh.2014.04.047_bb0125","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1016\/S0031-9384(98)00340-0","article-title":"Inhibition of food intake by CRF in chickens","volume":"66","author":"Denbow","year":"1999","journal-title":"Physiol Behav"},{"key":"10.1016\/j.physbeh.2014.04.047_bb0130","first-page":"1991","article-title":"Peripheral administration of human corticotropin-releasing hormone: a novel method to increase energy expenditure and fat oxidation in man","volume":"86","author":"Smith","year":"2001","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.physbeh.2014.04.047_bb0135","doi-asserted-by":"crossref","first-page":"2461","DOI":"10.2337\/db11-1278","article-title":"S6K1 in the central nervous system regulates energy expenditure via MC4R\/CRH pathways in response to deprivation of an essential amino acid","volume":"61","author":"Xia","year":"2012","journal-title":"Diabetes"},{"key":"10.1016\/j.physbeh.2014.04.047_bb0140","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1089\/thy.2007.0251","article-title":"The role of the thyrotropin-releasing hormone (TRH) neuron as a metabolic sensor","volume":"18","author":"Hollenberg","year":"2008","journal-title":"Thyroid"},{"key":"10.1016\/j.physbeh.2014.04.047_bb0145","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1016\/j.metabol.2009.10.018","article-title":"Alpha-lipoic acid increases energy expenditure by enhancing adenosine monophosphate-activated protein kinase-peroxisome proliferator-activated receptor-gamma coactivator-1alpha signaling in the skeletal muscle of aged mice","volume":"59","author":"Wang","year":"2010","journal-title":"Metabolism"},{"key":"10.1016\/j.physbeh.2014.04.047_bb0150","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/j.cbpa.2011.04.004","article-title":"AICAR and compound C regulate food intake independently of AMP-activated protein kinase in lines of chickens selected for high or low body weight","volume":"159","author":"Xu","year":"2011","journal-title":"Comp Biochem Physiol A Mol Integr Physiol"}],"container-title":["Physiology & Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0031938414002388?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0031938414002388?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T18:00:01Z","timestamp":1758477601000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0031938414002388"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,6]]},"references-count":30,"alternative-id":["S0031938414002388"],"URL":"https:\/\/doi.org\/10.1016\/j.physbeh.2014.04.047","relation":{},"ISSN":["0031-9384"],"issn-type":[{"value":"0031-9384","type":"print"}],"subject":[],"published":{"date-parts":[[2014,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The anorectic effects of alpha-lipoicacid are mediated by central AMPK and are not due to taste aversion in chicken (Gallus gallus)","name":"articletitle","label":"Article Title"},{"value":"Physiology & Behavior","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.physbeh.2014.04.047","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}