{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T00:01:34Z","timestamp":1758585694701,"version":"3.44.0"},"reference-count":40,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,10,1]],"date-time":"2016-10-01T00:00:00Z","timestamp":1475280000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,10,1]],"date-time":"2016-10-01T00:00:00Z","timestamp":1475280000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2016,10,1]],"date-time":"2016-10-01T00:00:00Z","timestamp":1475280000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2016,10,1]],"date-time":"2016-10-01T00:00:00Z","timestamp":1475280000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2016,10,1]],"date-time":"2016-10-01T00:00:00Z","timestamp":1475280000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2016,10,1]],"date-time":"2016-10-01T00:00:00Z","timestamp":1475280000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2016,10,1]],"date-time":"2016-10-01T00:00:00Z","timestamp":1475280000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Physiology & Behavior"],"published-print":{"date-parts":[[2016,10]]},"DOI":"10.1016\/j.physbeh.2016.04.037","type":"journal-article","created":{"date-parts":[[2016,4,30]],"date-time":"2016-04-30T22:33:49Z","timestamp":1462055629000},"page":"123-128","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"PA","title":["Serotonin release in the subfornical organ area induced by sodium and water intake in the rat"],"prefix":"10.1016","volume":"164","author":[{"given":"Makoto","family":"Takahashi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junichi","family":"Tanaka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.physbeh.2016.04.037_bb0005","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1016\/S0306-4522(00)00313-4","article-title":"Intrinsic osmosensitivity of subfornical organ neurons","volume":"100","author":"Anderson","year":"2000","journal-title":"Neuroscience"},{"key":"10.1016\/j.physbeh.2016.04.037_bb0015","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/S0006-8993(03)03015-4","article-title":"Central 5-HT2B\/2C and 5-HT3 receptor stimulation decreases salt intake in sodium-depleted rats","volume":"981","author":"Castro","year":"2003","journal-title":"Brain Res."},{"key":"10.1016\/j.physbeh.2016.04.037_bb0020","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1016\/S0091-3057(00)00226-4","article-title":"Central 5-HT4 receptors and drinking behavior","volume":"66","author":"Castro","year":"2002","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.physbeh.2016.04.037_bb0025","first-page":"R1470","article-title":"Forebrain angiotensin type 1 receptors and parabrachial serotonin in the control of NaCl and water intake","volume":"271","author":"Colombari","year":"1996","journal-title":"Am. J. Phys."},{"key":"10.1016\/j.physbeh.2016.04.037_bb0030","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1016\/S0091-3057(96)00457-1","article-title":"Effect of third ventricle administration of L-692,247, a selective 5-HT1D receptor agonist, on water intake in rats","volume":"57","author":"De Castro-e-Silva","year":"1997","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.physbeh.2016.04.037_bb0035","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/0304-3940(96)12931-1","article-title":"Effects of central \u03b1-adrenergic agonists on hormone-induced 3% NaCl and water intake","volume":"214","author":"De Paula","year":"1996","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.physbeh.2016.04.037_bb0040","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/0006-8993(91)91245-V","article-title":"Role of \u03b11- and \u03b12-adrenoceptors of the lateral hypothalamus in the dipsogenic response to central angiotesin II in rats","volume":"560","author":"Ferrari","year":"1991","journal-title":"Brain Res."},{"key":"10.1016\/j.physbeh.2016.04.037_bb0045","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1037\/0735-7044.105.5.721","article-title":"Effects of lesions of the ventral ventral median preoptic nucleus or subfornical organ on drinking and salt appetite after deoxycorticosterone acetate or yohimbine","volume":"105","author":"Fitts","year":"1991","journal-title":"Behav. Neurosci."},{"key":"10.1016\/j.physbeh.2016.04.037_bb0050","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0304-3940(92)90844-W","article-title":"c-Fos protein expression in the rat subfornical organ following osmotic stimulation","volume":"139","author":"Giovannelli","year":"1992","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.physbeh.2016.04.037_bb0055","first-page":"R882","article-title":"Effect of paraventricular nucleus lesions on drinking and pressor response to ANG II","volume":"255","author":"Gutman","year":"1988","journal-title":"Am. J. Phys."},{"key":"10.1016\/j.physbeh.2016.04.037_bb0060","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/0006-8993(95)01425-X","article-title":"Effect of lesions of forebrain circumventricular organs on c-Fos expression in the central nervous system to plasma hypernatremia","volume":"713","author":"Hochstenbach","year":"1996","journal-title":"Brain Res."},{"key":"10.1016\/j.physbeh.2016.04.037_bb0065","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1006\/frne.1997.0153","article-title":"The neuroendocrinology of thirst and salt appetite: visceral sensory signals and mechanisms of central integration","volume":"18","author":"Johnson","year":"1997","journal-title":"Front. Neuroendocrinol."},{"key":"10.1016\/j.physbeh.2016.04.037_bb0070","series-title":"Central Nervous System Mechanisms in Hypertension","first-page":"9","article-title":"Localization of aortic and carotid baroreceptor and chemoreceptor primary afferents in the brain stem","author":"Karia","year":"1981"},{"key":"10.1016\/j.physbeh.2016.04.037_bb0075","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1097\/00001756-199210000-00020","article-title":"Increased monoamine turnover in the subfornical organ area following body fluid depletion","volume":"3","author":"Kariya","year":"1992","journal-title":"Neuroreport"},{"key":"10.1016\/j.physbeh.2016.04.037_bb0080","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1016\/0006-8993(86)91161-3","article-title":"Bi-directional, chemically specified neural connections between the subfornical organ and the midbrain raphe system","volume":"384","author":"Lind","year":"1986","journal-title":"Brain Res."},{"key":"10.1016\/j.physbeh.2016.04.037_bb0085","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1523\/JNEUROSCI.02-08-01043.1982","article-title":"Subfornical organ-median preoptic connections and drinking and pressor responses to angiotensin II","volume":"2","author":"Lind","year":"1982","journal-title":"J. Neurosci."},{"key":"10.1016\/j.physbeh.2016.04.037_bb0090","first-page":"R382","article-title":"Subfornical organ: forebrain site of pressor and dipsogenic action of angiotensin II","volume":"239","author":"Mangiapane","year":"1980","journal-title":"Am. J. Phys."},{"key":"10.1016\/j.physbeh.2016.04.037_bb0095","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/S0006-8993(02)03486-8","article-title":"Central serotonergic and adrenergic\/imidazoline inhibitory mechanisms on sodium and water intake","volume":"956","author":"Margatho","year":"2002","journal-title":"Brain Res."},{"key":"10.1016\/j.physbeh.2016.04.037_bb0100","first-page":"91","article-title":"Circumventricular organ: neuroendocrine interfaces between the brain the hemal milieu","volume":"11","author":"McKinley","year":"1990","journal-title":"Front. Neuroendocrinol."},{"key":"10.1016\/j.physbeh.2016.04.037_bb0105","doi-asserted-by":"crossref","DOI":"10.1007\/978-3-642-55532-9","article-title":"Subfornical organ, OVLT and area postrema","author":"McKinley","year":"2003","journal-title":"Adv. Anat. Embryol. Cell Biol."},{"key":"10.1016\/j.physbeh.2016.04.037_bb0110","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/S0006-8993(98)00530-7","article-title":"Salt appetite: interaction of forebrain angiotensinergic and hindbrain serotonergic mechanisms","volume":"801","author":"Menani","year":"1998","journal-title":"Brain Res."},{"key":"10.1016\/j.physbeh.2016.04.037_bb0115","first-page":"R126","article-title":"Hindbrain serotonin and the rapid induction of sodium appetite","volume":"279","author":"Menani","year":"2000","journal-title":"Am. J. Phys."},{"key":"10.1016\/j.physbeh.2016.04.037_bb0120","first-page":"R1044","article-title":"Lateral parabrachial nucleus serotonergic mechanisms: angiotensin-induced pressor and drinking responses","volume":"269","author":"Menani","year":"1995","journal-title":"Am. J. Phys."},{"key":"10.1016\/j.physbeh.2016.04.037_bb0125","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/S0006-8993(02)02963-3","article-title":"Forebrain circumventricular organs mediate salt appetite induced by intravenous angiotensin II in rats","volume":"949","author":"Morris","year":"2002","journal-title":"Brain Res."},{"key":"10.1016\/j.physbeh.2016.04.037_bb0130","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/0006-8993(91)90760-S","article-title":"Intravenous hypertonic saline induces Fos immunoreactivity in neurons throughout the lamina terminalis","volume":"561","author":"Oldfield","year":"1991","journal-title":"Brain Res."},{"key":"10.1016\/j.physbeh.2016.04.037_bb0140","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/S0031-9384(01)00625-4","article-title":"Effects of SFO lesions on salt appetite during multiple sodium depletions","volume":"74","author":"Ruhf","year":"2001","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.physbeh.2016.04.037_bb0145","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/0006-8993(80)91117-8","article-title":"Efferent connections of the parabrachial nucleus in the rat","volume":"197","author":"Saper","year":"1980","journal-title":"Brain Res."},{"key":"10.1016\/j.physbeh.2016.04.037_bb0150","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/0006-8993(88)90251-X","article-title":"Osmosensitive neurons in the rat subfornical organ","volume":"461","author":"Sibbald","year":"1988","journal-title":"Brain Res."},{"key":"10.1016\/j.physbeh.2016.04.037_bb0155","first-page":"72","article-title":"The effects of biogenic amines, vasopressin and hypertonic saline on blood pressure and drinking at the subfornical organ (SFO)","volume":"8","author":"Simpson","year":"1982","journal-title":"Soc. Neurosci. Abstr."},{"key":"10.1016\/j.physbeh.2016.04.037_bb0160","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1006\/appe.1998.0169","article-title":"Influence of salt intake, ANG II synthesis, and SFO lesion on thirst and blood pressure during sodium depletion","volume":"31","author":"Starbuck","year":"1999","journal-title":"Appetite"},{"key":"10.1016\/j.physbeh.2016.04.037_bb0165","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/S0006-8993(02)03162-1","article-title":"Subfornical organ disconnection and Fos-like immunoreactivity in hypothalamic nuclei after intragastric hypertonic saline","volume":"951","author":"Starbuck","year":"2002","journal-title":"Brain Res."},{"key":"10.1016\/j.physbeh.2016.04.037_bb0170","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1037\/0735-7044.111.1.206","article-title":"Interaction of hydration and subfornical organ lesions in sodium-depletion induced salt appetite","volume":"111","author":"Starbuck","year":"1997","journal-title":"Behav. Neurosci."},{"key":"10.1016\/j.physbeh.2016.04.037_bb0175","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/S0091-3057(03)00195-3","article-title":"GABAergic modulation of the ANG II-induced drinking response in the rat medial preoptic area","volume":"76","author":"Tanaka","year":"2003","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.physbeh.2016.04.037_bb0180","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/S0166-4328(00)00320-X","article-title":"Angiotensinergic and noradrenergic mechanisms in the hypothalamic paraventricular nucleus participate in the drinking response induced by activation of the subfornical organ in rats","volume":"118","author":"Tanaka","year":"2001","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.physbeh.2016.04.037_bb0190","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1016\/S0196-9781(03)00164-5","article-title":"Angiotensin II reduces serotonin release in the rat subfornical organ area","volume":"24","author":"Tanaka","year":"2003","journal-title":"Peptides"},{"key":"10.1016\/j.physbeh.2016.04.037_bb0195","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1006\/exnr.1993.1025","article-title":"Involvement of neurons sensitive to angiotensin II in the median preoptic nucleus in the drinking response induced by angiotensin II activation of the subfornical organ in rats","volume":"119","author":"Tanaka","year":"1993","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.physbeh.2016.04.037_bb0200","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1006\/exnr.2000.7611","article-title":"Activation of serotonergic pathways from the midbrain raphe system to the subfornical organ by hemorrhage in the rat","volume":"169","author":"Tanaka","year":"2001","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.physbeh.2016.04.037_bb0205","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/S0361-9230(97)00371-7","article-title":"Responses of raphe nucleus projecting subfornical organ neurons to angiotensin II in rats","volume":"45","author":"Tanaka","year":"1998","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.physbeh.2016.04.037_bb0210","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/0006-8993(90)90245-7","article-title":"Subfornical organ lesion decreases sodium appetite in the sodium-depleted rat","volume":"526","author":"Weisinger","year":"1990","journal-title":"Brain Res."},{"key":"10.1016\/j.physbeh.2016.04.037_bb0215","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1016\/S0166-4328(02)00193-6","article-title":"Salt appetite of adrenalectomized rats after a lesion of the SFO","volume":"136","author":"Wilson","year":"2002","journal-title":"Behav. Brain Res."}],"container-title":["Physiology & Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0031938416301858?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0031938416301858?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T18:03:46Z","timestamp":1758477826000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0031938416301858"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,10]]},"references-count":40,"alternative-id":["S0031938416301858"],"URL":"https:\/\/doi.org\/10.1016\/j.physbeh.2016.04.037","relation":{},"ISSN":["0031-9384"],"issn-type":[{"type":"print","value":"0031-9384"}],"subject":[],"published":{"date-parts":[[2016,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Serotonin release in the subfornical organ area induced by sodium and water intake in the rat","name":"articletitle","label":"Article Title"},{"value":"Physiology & Behavior","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.physbeh.2016.04.037","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}