{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T20:24:03Z","timestamp":1790886243516,"version":"4.1.0"},"reference-count":63,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,12,1]],"date-time":"2016-12-01T00:00:00Z","timestamp":1480550400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Ministerio de Econom\u00eda y Competitividad, Spain, and Fondo Europeo de Desarrollo Regional [FEDER]","award":["AGL2010-21578-C03-01"],"award-info":[{"award-number":["AGL2010-21578-C03-01"]}]},{"name":"Ministerio de Econom\u00eda y Competitividad, Spain, and Fondo Europeo de Desarrollo Regional [FEDER]","award":["AGL2011-30598-C03-02"],"award-info":[{"award-number":["AGL2011-30598-C03-02"]}]},{"DOI":"10.13039\/501100002809","name":"Generalitat de Catalunya","doi-asserted-by":"publisher","award":["2014 SGR4"],"award-info":[{"award-number":["2014 SGR4"]}],"id":[{"id":"10.13039\/501100002809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Physiology &amp; Behavior"],"published-print":{"date-parts":[[2016,12]]},"DOI":"10.1016\/j.physbeh.2016.10.005","type":"journal-article","created":{"date-parts":[[2016,10,15]],"date-time":"2016-10-15T07:16:57Z","timestamp":1476515817000},"page":"374-381","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":20,"special_numbering":"C","title":["Effect of handling on neurotransmitter profile in pig brain according to fear related behaviour"],"prefix":"10.1016","volume":"167","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9440-7236","authenticated-orcid":false,"given":"Laura","family":"Arroyo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ricard","family":"Carreras","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Valent","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raquel","family":"Pe\u00f1a","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva","family":"Mainau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2634-3138","authenticated-orcid":false,"given":"Antonio","family":"Velarde","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1456-4136","authenticated-orcid":false,"given":"Josefa","family":"Sabri\u00e0","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4213-2274","authenticated-orcid":false,"given":"Anna","family":"Bassols","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.physbeh.2016.10.005_bb0005","series-title":"Principles of Neural Science","author":"Kandel","year":"2013"},{"key":"10.1016\/j.physbeh.2016.10.005_bb0010","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.brainres.2011.12.049","article-title":"Stress, neurotransmitters, corticosterone and body-brain integration","volume":"1476","author":"Mora","year":"2012","journal-title":"Brain Res."},{"key":"10.1016\/j.physbeh.2016.10.005_bb0015","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1046\/j.1439-0442.2000.00262.x","article-title":"The effect of acute restraint stress on regional brain neurotransmitter levels in stress-susceptible pietrain pigs","volume":"47","author":"Piekarzewska","year":"2000","journal-title":"J. Vet. Med. A Physiol. Pathol. Clin. Med."},{"key":"10.1016\/j.physbeh.2016.10.005_bb0020","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/j.physbeh.2007.03.016","article-title":"A critical review of fear tests used on cattle, pigs, sheep, poultry and horses","volume":"92","author":"Forkman","year":"2007","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.physbeh.2016.10.005_bb0025","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1016\/j.brainresbull.2006.02.007","article-title":"Serotoninergic activation of the basolateral amygdala and modulation of tonic immobility in guinea pig","volume":"69","author":"Leite-Panissi","year":"2006","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.physbeh.2016.10.005_bb0030","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1016\/S0031-9384(97)00351-X","article-title":"Participation of the medial and anterior hypothalamus in the modulation of tonic immobility in guinea pigs","volume":"62","author":"De Oliveira","year":"1997","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.physbeh.2016.10.005_bb0035","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.domaniend.2013.11.005","article-title":"Differential expression of hypothalamic fear- and stress-related genes in broiler chickens showing short or long tonic immobility","volume":"47","author":"Wang","year":"2014","journal-title":"Domest. Anim. Endocrinol."},{"key":"10.1016\/j.physbeh.2016.10.005_bb0040","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.applanim.2008.11.004","article-title":"Consistency and influence on performance of behavioural differences in large white and landrace purebred pigs","volume":"117","author":"de Sevilla","year":"2009","journal-title":"Appl. Anim. Behav. Sci."},{"key":"10.1016\/j.physbeh.2016.10.005_bb0045","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/S0168-1591(99)00094-5","article-title":"Individual behavioural characteristics in pigs and their impact on production","volume":"66","author":"van Erp-van der Kooij","year":"2000","journal-title":"Appl. Anim. Behav. Sci."},{"key":"10.1016\/j.physbeh.2016.10.005_bb0050","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/S0168-1591(98)00196-8","article-title":"Tonic immobility and emergence time in pigs\u2014more evidence for behavioural strategies","volume":"61","author":"Erhard","year":"1999","journal-title":"Appl. Anim. Behav. Sci."},{"key":"10.1016\/j.physbeh.2016.10.005_bb0055","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/S0168-1591(99)00028-3","article-title":"Individual differences in tonic immobility may reflect behavioural strategies","volume":"64","author":"Erhard","year":"1999","journal-title":"Appl. Anim. Behav. Sci."},{"key":"10.1016\/j.physbeh.2016.10.005_bb0060","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/0168-1591(93)90118-9","article-title":"Individual behavioural characteristics in pigs","volume":"37","author":"Hessing","year":"1993","journal-title":"Appl. Anim. Behav. Sci."},{"key":"10.1016\/j.physbeh.2016.10.005_bb0065","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1016\/S0031-9384(02)00877-6","article-title":"Individual differences in behavioral and physiological responses to restraint stress in pigs","volume":"77","author":"Geverink","year":"2002","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.physbeh.2016.10.005_bb0070","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.2527\/2004.8241227x","article-title":"Backtest type and housing condition of pigs influence energy metabolism","volume":"82","author":"Geverink","year":"2004","journal-title":"J. Anim. Sci."},{"key":"10.1016\/j.physbeh.2016.10.005_bb0075","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.physbeh.2014.02.059","article-title":"Social support in pigs with different coping styles","volume":"129","author":"Reimert","year":"2014","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.physbeh.2016.10.005_bb0080","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/S0014-2999(99)00441-0","article-title":"Effects of conditioned fear stress on serotonin neurotransmission and freezing behavior in rats","volume":"378","author":"Hashimoto","year":"1999","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.physbeh.2016.10.005_bb0085","doi-asserted-by":"crossref","first-page":"249","DOI":"10.2527\/1997.751249x","article-title":"Assessment of stress during handling and transport","volume":"75","author":"Grandin","year":"1997","journal-title":"J. Anim. Sci."},{"key":"10.1016\/j.physbeh.2016.10.005_bb0090","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/S0309-1740(99)00130-8","article-title":"A survey of pre-slaughter conditions, halothane gene frequency, and carcass and meat quality in five Spanish pig commercial abattoirs","volume":"55","author":"Gispert","year":"2000","journal-title":"Meat Sci."},{"key":"10.1016\/j.physbeh.2016.10.005_bb0095","doi-asserted-by":"crossref","first-page":"968","DOI":"10.2527\/1993.714968x","article-title":"Regional brain neurotransmitter concentrations in stress-susceptible pigs","volume":"71","author":"Adeola","year":"1993","journal-title":"J. Anim. Sci."},{"key":"10.1016\/j.physbeh.2016.10.005_bb0100","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1046\/j.1439-0388.2003.00380.x","article-title":"Genetic differences in brain monoamines level in Pietrain and Duroc pigs exposed to acute restraint stress","volume":"120","author":"Rosochacki","year":"2003","journal-title":"J. Anim. Breed. Genet."},{"key":"10.1016\/j.physbeh.2016.10.005_bb0105","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.applanim.2009.11.015","article-title":"Aggression in replacement grower and finisher gilts fed a short-term high-tryptophan diet and the effect of long-term human\u2013animal interaction","volume":"122","author":"Poletto","year":"2010","journal-title":"Appl. Anim. Behav. Sci."},{"key":"10.1016\/j.physbeh.2016.10.005_bb0110","doi-asserted-by":"crossref","first-page":"3107","DOI":"10.2527\/jas.2009-1876","article-title":"Aggressiveness and brain amine concentration in dominant and subordinate finishing pigs fed the \u03b2-adrenoreceptor agonist ractopamine","volume":"88","author":"Poletto","year":"2010","journal-title":"J. Anim. Sci."},{"key":"10.1016\/j.physbeh.2016.10.005_bb0115","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.brainres.2010.11.035","article-title":"Gene expression of serotonin and dopamine receptors and monoamine oxidase-A in the brain of dominant and subordinate pubertal domestic pigs (Sus scrofa) fed a \u03b2-adrenoreceptor agonist","volume":"1381","author":"Poletto","year":"2011","journal-title":"Brain Res."},{"key":"10.1016\/j.physbeh.2016.10.005_bb0120","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.physbeh.2015.02.049","article-title":"Evidence for a link between tail biting and central monoamine metabolism in pigs (Sus scrofa domestica)","volume":"143","author":"Valros","year":"2015","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.physbeh.2016.10.005_bb0125","doi-asserted-by":"crossref","first-page":"1888","DOI":"10.2527\/1992.7061888x","article-title":"Hypothalamic neurotransmitter concentrations and meat quality in stressed pigs offered excess dietary tryptophan and tyrosine","volume":"70","author":"Adeola","year":"1992","journal-title":"J. Anim. Sci."},{"key":"10.1016\/j.physbeh.2016.10.005_bb0130","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1080\/13556210310001602194","article-title":"Release of neurotransmitters from rat brain nerve terminals after chronic ethanol ingestion: differential effects in cortex and hippocampus","volume":"8","author":"Sabria","year":"2003","journal-title":"Addict. Biol."},{"key":"10.1016\/j.physbeh.2016.10.005_bb0135","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1007\/s00418-013-1081-1","article-title":"Serotonergic innervation of the amygdala: targets, receptors, and implications for stress and anxiety","volume":"139","author":"Asan","year":"2013","journal-title":"Histochem. Cell Biol."},{"key":"10.1016\/j.physbeh.2016.10.005_bb0140","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0166-4328(99)00121-7","article-title":"Amygdala, hippocampus and discriminative fear conditioning to context","volume":"108","author":"Antoniadis","year":"2000","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.physbeh.2016.10.005_bb0145","doi-asserted-by":"crossref","first-page":"199","DOI":"10.3389\/fnbeh.2014.00199","article-title":"Serotonin-prefrontal cortical circuitry in anxiety and depression phenotypes: pivotal role of pre- and post-synaptic 5-HT1A receptor expression","volume":"8","author":"Albert","year":"2014","journal-title":"Front. Behav. Neurosci."},{"key":"10.1016\/j.physbeh.2016.10.005_bb0150","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1111\/j.1749-6632.2010.05896.x","article-title":"Hippocampus, amygdala, and stress: interacting systems that affect susceptibility to addiction","volume":"1216","author":"Belujon","year":"2011","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.physbeh.2016.10.005_bb0155","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1038\/nrn3945","article-title":"Neuronal circuits for fear and anxiety","volume":"16","author":"Tovote","year":"2015","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.physbeh.2016.10.005_bb0160","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1002\/da.10016","article-title":"Circuits and systems in stress. I. Preclinical studies","volume":"15","author":"Vermetten","year":"2002","journal-title":"Depress. Anxiety"},{"key":"10.1016\/j.physbeh.2016.10.005_bb0165","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/S0006-8993(00)02950-4","article-title":"The neurobiology of stress: from serendipity to clinical relevance","volume":"886","author":"McEwen","year":"2000","journal-title":"Brain Res."},{"key":"10.1016\/j.physbeh.2016.10.005_bb0170","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1038\/nrn2632","article-title":"The neuro-symphony of stress","volume":"10","author":"Jo\u00ebls","year":"2009","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.physbeh.2016.10.005_bb0175","doi-asserted-by":"crossref","first-page":"20142516","DOI":"10.1098\/rspb.2014.2516","article-title":"Regulation of dopamine system responsivity and its adaptive and pathological response to stress","volume":"282","author":"Belujon","year":"2015","journal-title":"Proc. Biol. Sci."},{"key":"10.1016\/j.physbeh.2016.10.005_bb0180","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.ejphar.2014.10.031","article-title":"Serotonin: a never-ending story","volume":"753","author":"Olivier","year":"2015","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.physbeh.2016.10.005_bb0185","doi-asserted-by":"crossref","first-page":"1174","DOI":"10.1016\/j.neubiorev.2008.04.006","article-title":"Corticosteroid\u2013serotonin interactions in the neurobiological mechanisms of stress-related disorders","volume":"32","author":"Lanfumey","year":"2008","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.physbeh.2016.10.005_bb0190","doi-asserted-by":"crossref","first-page":"1683","DOI":"10.1016\/0024-3205(96)00066-5","article-title":"Serotonin and the regulation of hypothalamic-pituitary-adrenal axis function","volume":"58","author":"Dinan","year":"1996","journal-title":"Life Sci."},{"key":"10.1016\/j.physbeh.2016.10.005_bb0195","doi-asserted-by":"crossref","first-page":"R79","DOI":"10.1016\/j.cub.2012.11.055","article-title":"The biology of fear","volume":"23","author":"Adolphs","year":"2013","journal-title":"Curr. Biol."},{"key":"10.1016\/j.physbeh.2016.10.005_bb0200","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/0006-8993(95)00349-U","article-title":"Regional differences in the effects of forced swimming on extracellular levels of 5-hydroxytryptamine and 5-hydroxyindoleacetic acid","volume":"682","author":"Kirby","year":"1995","journal-title":"Brain Res."},{"key":"10.1016\/j.physbeh.2016.10.005_bb0205","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/S0006-8993(98)00368-0","article-title":"Escapable and inescapable stress differentially and selectively alter extracellular levels of 5-HT in the ventral hippocampus and dorsal periaqueductal gray of the rat","volume":"797","author":"Amat","year":"1998","journal-title":"Brain Res."},{"key":"10.1016\/j.physbeh.2016.10.005_bb0210","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1111\/j.1460-9568.1994.tb00619.x","article-title":"Comparison of stress-induced changes in noradrenergic and serotonergic neurons in the rat hippocampus using microdialysis","volume":"6","author":"Vahabzadeh","year":"1994","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.physbeh.2016.10.005_bb0215","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/0304-3940(96)12982-7","article-title":"Conflict situation increases serotonin release in rat dorsal hippocampus: in vivo study with microdialysis and Vogel test","volume":"215","author":"Matsuo","year":"1996","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.physbeh.2016.10.005_bb0220","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/S0006-8993(96)00809-8","article-title":"A microdialysis examination of serotonin release in the rat forebrain induced by behavioral\/environmental manipulations","volume":"739","author":"Rueter","year":"1996","journal-title":"Brain Res."},{"key":"10.1016\/j.physbeh.2016.10.005_bb0225","doi-asserted-by":"crossref","first-page":"1479","DOI":"10.1111\/j.1460-9568.1996.tb01610.x","article-title":"Dissociations in hippocampal 5-hydroxytryptamine release in the rat following Pavlovian aversive conditioning to discrete and contextual stimuli","volume":"8","author":"Wilkinson","year":"1996","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.physbeh.2016.10.005_bb0230","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1016\/S0091-3057(02)01047-X","article-title":"Rapid habituation of hippocampal serotonin and norepinephrine release and anxiety-related behaviors, but not plasma corticosterone levels, to repeated footshock","volume":"74","author":"Hajos-Korcsok","year":"2003","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.physbeh.2016.10.005_bb0235","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1080\/00071660600610534","article-title":"Corticosterone and fear behaviour in white and brown caged laying hens","volume":"47","author":"Fraisse","year":"2006","journal-title":"Br. Poult. Sci."},{"key":"10.1016\/j.physbeh.2016.10.005_bb0240","first-page":"359","article-title":"Modulation of fear extinction by stress, stress hormones and estradiol: a review","volume":"9","author":"Stockhorst","year":"2015","journal-title":"Front. Behav. Neurosci."},{"key":"10.1016\/j.physbeh.2016.10.005_bb0245","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1086\/418981","article-title":"Fear and fearfulness in animals","volume":"70","author":"Boissy","year":"1995","journal-title":"Q. Rev. Biol."},{"key":"10.1016\/j.physbeh.2016.10.005_bb0250","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.physbeh.2013.05.018","article-title":"Relations between peripheral and brain serotonin measures and behavioural responses in a novelty test in pigs","volume":"118","author":"Ursinus","year":"2013","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.physbeh.2016.10.005_bb0255","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1016\/j.bbr.2013.07.043","article-title":"Effects of early serotonin programming on behavior and central monoamine concentrations in an avian model","volume":"253","author":"Dennis","year":"2013","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.physbeh.2016.10.005_bb0260","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/S0014-2999(03)01279-2","article-title":"A robust animal model of state anxiety: fear-potentiated behaviour in the elevated plus-maze","volume":"463","author":"Korte","year":"2003","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.physbeh.2016.10.005_bb0265","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1002\/hipo.10178","article-title":"Endogenous 5-HT inhibits firing activity of hippocampal CA1 pyramidal neurons during conditioned fear stress-induced freezing behavior through stimulating 5-HT1A","volume":"14","author":"Tada","year":"2004","journal-title":"Hippocampus"},{"key":"10.1016\/j.physbeh.2016.10.005_bb0270","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1016\/S0006-3223(00)01041-6","article-title":"Altered fear circuits in 5-HT 1A receptor KO mice","volume":"48","author":"Gross","year":"2000","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.physbeh.2016.10.005_bb0275","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/0166-4328(95)80001-8","article-title":"Brain microdialysis and its application for the study of animal behaviour","volume":"70","author":"Westerink","year":"1995","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.physbeh.2016.10.005_bb0280","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.bbr.2014.07.052","article-title":"Serotonin and stress coping","volume":"277","author":"Puglisi-Allegra","year":"2015","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.physbeh.2016.10.005_bb0285","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.jchemneu.2011.05.002","article-title":"Development by environment interactions controlling tryptophan hydroxylase expression","volume":"41","author":"Hale","year":"2011","journal-title":"J. Chem. Neuroanat."},{"key":"10.1016\/j.physbeh.2016.10.005_bb0290","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1016\/j.euroneuro.2008.12.005","article-title":"Spatio-temporal expression of tryptophan hydroxylase isoforms in murine and human brain: convergent data from Tph2 knockout mice","volume":"19","author":"Gutknecht","year":"2009","journal-title":"Eur. Neuropsychopharmacol."},{"key":"10.1016\/j.physbeh.2016.10.005_bb0295","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.abb.2010.12.017","article-title":"Tyrosine hydroxylase and regulation of dopamine synthesis","volume":"508","author":"Daubner","year":"2011","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.physbeh.2016.10.005_bb0300","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/S0166-2236(00)01687-8","article-title":"Stress-triggered activation of gene expression in catecholaminergic systems: dynamics of transcriptional events","volume":"24","author":"Sabban","year":"2001","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.physbeh.2016.10.005_bb0305","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1042\/BJ20071033","article-title":"Activation and stabilization of human tryptophan hydroxylase 2 by phosphorylation and 14-3-3 binding","volume":"410","author":"Winge","year":"2008","journal-title":"Biochem. J."},{"key":"10.1016\/j.physbeh.2016.10.005_bb0310","doi-asserted-by":"crossref","first-page":"1567","DOI":"10.1111\/j.1471-4159.2007.04855.x","article-title":"Phosphorylation and activation of tryptophan hydroxylase 2: identification of serine-19 as the substrate site for calcium, calmodulin-dependent protein kinase II","volume":"103","author":"Kuhn","year":"2007","journal-title":"J. Neurochem."},{"key":"10.1016\/j.physbeh.2016.10.005_bb0315","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1111\/jnc.12779","article-title":"Functional characterization of the S41Y (C2755A) polymorphism of tryptophan hydroxylase 2","volume":"130","author":"Carkaci-Salli","year":"2014","journal-title":"J. Neurochem."}],"container-title":["Physiology &amp; Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0031938416303900?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0031938416303900?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,7]],"date-time":"2018-09-07T13:20:37Z","timestamp":1536326437000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0031938416303900"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,12]]},"references-count":63,"alternative-id":["S0031938416303900"],"URL":"https:\/\/doi.org\/10.1016\/j.physbeh.2016.10.005","relation":{},"ISSN":["0031-9384"],"issn-type":[{"value":"0031-9384","type":"print"}],"subject":[],"published":{"date-parts":[[2016,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effect of handling on neurotransmitter profile in pig brain according to fear related behaviour","name":"articletitle","label":"Article Title"},{"value":"Physiology & Behavior","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.physbeh.2016.10.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}