{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,13]],"date-time":"2025-09-13T15:45:15Z","timestamp":1757778315206},"reference-count":86,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,12,1]],"date-time":"2017-12-01T00:00:00Z","timestamp":1512086400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Physiology &amp; Behavior"],"published-print":{"date-parts":[[2017,12]]},"DOI":"10.1016\/j.physbeh.2017.09.014","type":"journal-article","created":{"date-parts":[[2017,9,16]],"date-time":"2017-09-16T03:47:35Z","timestamp":1505533655000},"page":"1-9","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["The effect of directed photic stimulation of the pineal on experimental Parkinson's disease"],"prefix":"10.1016","volume":"182","author":[{"given":"Gregory L.","family":"Willis","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher B.","family":"Freelance","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.physbeh.2017.09.014_bb0005","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1007\/s00441-002-0574-3","article-title":"Neurotransmitters of the retino-hypothalamic tract","volume":"309","author":"Hannibal","year":"2002","journal-title":"Cell Tissue Res."},{"issue":"4","key":"10.1016\/j.physbeh.2017.09.014_bb0010","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1111\/j.1442-9071.1987.tb00092.x","article-title":"The human pineal gland: a review of the \u201cthird eye\u201d and the effect of light","volume":"15","author":"Booth","year":"1987","journal-title":"Aust. N. Z. J. Ophthalmol."},{"issue":"3388","key":"10.1016\/j.physbeh.2017.09.014_bb0015","doi-asserted-by":"crossref","first-page":"1573","DOI":"10.1126\/science.130.3388.1573","article-title":"Parietal eye nerve in the fence lizard","volume":"130","author":"Eakin","year":"1959","journal-title":"Science (New York, N.Y.)"},{"issue":"1","key":"10.1016\/j.physbeh.2017.09.014_bb0020","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1562\/2006-02-24-IR-813","article-title":"A median third eye: pineal gland retraces evolution of vertebrate photoreceptive organs","volume":"83","author":"Mano","year":"2007","journal-title":"Photochem. Photobiol."},{"issue":"4","key":"10.1016\/j.physbeh.2017.09.014_bb0025","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1007\/BF01252023","article-title":"Morphogenesis of the parietal complex of Lacerta vivipara J. Considerations on the origin of the third eye of lacertilians","volume":"41","author":"Meiniel","year":"1977","journal-title":"J. Neural Transm."},{"issue":"1\u20132","key":"10.1016\/j.physbeh.2017.09.014_bb0030","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1080\/07420520500464551","article-title":"Period2 expression pattern and its role in the development of the pineal circadian clock in zebrafish","volume":"23","author":"Ziv","year":"2006","journal-title":"Chronobiol. Int."},{"issue":"1","key":"10.1016\/j.physbeh.2017.09.014_bb0035","first-page":"13","article-title":"Manganese and extrapyramidal disorders (a critical review and tribute to Dr. George C. Cotzias)","volume":"5","author":"Barbeau","year":"1984","journal-title":"Neurotoxicology"},{"issue":"5","key":"10.1016\/j.physbeh.2017.09.014_bb0040","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1111\/j.1600-0749.2004.00185.x","article-title":"Melatonin, melatonin receptors and melanophores: a moving story","volume":"17","author":"Sugden","year":"2004","journal-title":"Pigment Cell Res."},{"key":"10.1016\/j.physbeh.2017.09.014_bb0045","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1046\/j.1471-4159.2002.00885.x","article-title":"Desensitization of pigment granule aggregation in Xenopus leavis melanophores: melatonin degradation rather than receptor down-regulation is responsible","volume":"81","author":"Teh","year":"2002","journal-title":"J. Neurochem."},{"issue":"4\u20135","key":"10.1016\/j.physbeh.2017.09.014_bb0050","first-page":"245","article-title":"Parkinson's disease as a neuroendocrine disorder of circadian function: dopamine-melatonin imbalance and the visual system in the genesis and progression of the degenerative process","volume":"19","author":"Willis","year":"2008","journal-title":"Rev. Neurosci."},{"issue":"5","key":"10.1016\/j.physbeh.2017.09.014_bb0055","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1016\/S0031-9384(99)00023-2","article-title":"A therapeutic role for melatonin antagonism in experimental models of Parkinson's disease","volume":"66","author":"Willis","year":"1999","journal-title":"Physiol. Behav."},{"issue":"2","key":"10.1016\/j.physbeh.2017.09.014_bb0060","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1515\/revneuro-2011-0072","article-title":"A historical justification for and retrospective analysis of the systematic application of light therapy in Parkinson's disease","volume":"23","author":"Willis","year":"2012","journal-title":"Rev. Neurosci."},{"issue":"3","key":"10.1016\/j.physbeh.2017.09.014_bb0065","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1080\/07420520701420717","article-title":"Primary and secondary features of Parkinson's disease improve with strategic exposure to bright light: a case series study","volume":"24","author":"Willis","year":"2007","journal-title":"Chronobiol. Int."},{"key":"10.1016\/j.physbeh.2017.09.014_bb0070","article-title":"Management of sleep disorders in Parkinson's disease and multiple system atrophy","volume":"24","author":"Videnovic","year":"2017","journal-title":"Mov. Disord."},{"key":"10.1016\/j.physbeh.2017.09.014_bb0075","first-page":"195","article-title":"Depigmentation in the nerve cells of the substantia nigra and locus ceruleus in Parkinsonism","volume":"5","author":"Forno","year":"1974","journal-title":"Adv. Neurol."},{"issue":"3","key":"10.1016\/j.physbeh.2017.09.014_bb0080","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1111\/ene.12613","article-title":"Substantia nigra neuromelanin magnetic resonance imaging in de novo Parkinson's disease patients","volume":"22","author":"Reimao","year":"2015","journal-title":"Eur. J. Neurol."},{"issue":"4","key":"10.1016\/j.physbeh.2017.09.014_bb0085","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1007\/BF02263482","article-title":"The apparent autoxidation rate of catechols in dopamine-rich regions of human brains increases with the degree of depigmentation of substantia nigra","volume":"1","author":"Fornstedt","year":"1989","journal-title":"J. Neural Transm. Park. Dis. Dement. Sect."},{"key":"10.1016\/j.physbeh.2017.09.014_bb0090","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.bbr.2004.11.030","article-title":"The therapeutic effects of dopmaine replecement therapy and its psychiatric side effects are mediated by pineal function","volume":"160","author":"Willis","year":"2005","journal-title":"Behav. Brain Res."},{"issue":"7","key":"10.1016\/j.physbeh.2017.09.014_bb0095","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1358\/dnp.2005.18.7.939349","article-title":"The role of ML-23 and other melatonin analogues in the treatment and management of Parkinson's disease","volume":"18","author":"Willis","year":"2005","journal-title":"Drug News Perspect."},{"key":"10.1016\/j.physbeh.2017.09.014_bb0100","doi-asserted-by":"crossref","first-page":"317879","DOI":"10.1155\/2014\/317879","article-title":"Eyes as gateways for environmental light to the substantia nigra: relevance in Parkinson's disease","volume":"2014","author":"Romeo","year":"2014","journal-title":"Sci. World J."},{"key":"10.1016\/j.physbeh.2017.09.014_bb0105","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1038\/srep01395","article-title":"Bright light exposure reduces TH-positive dopamine neurons: implications of light pollution in Parkinson's disease epidemiology","volume":"3","author":"Romeo","year":"2013","journal-title":"Sci Rep"},{"issue":"11","key":"10.1016\/j.physbeh.2017.09.014_bb0110","doi-asserted-by":"crossref","DOI":"10.1093\/ijnp\/pyv079","article-title":"Making Sense of optogenetics","volume":"18","author":"Guru","year":"2015","journal-title":"Int. J. Neuropsychopharmacol."},{"key":"10.1016\/j.physbeh.2017.09.014_bb0115","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/B978-0-12-404706-8.00010-3","article-title":"Optogenetic neuromodulation","volume":"107","author":"Kalanithi","year":"2012","journal-title":"Int. Rev. Neurobiol."},{"issue":"5","key":"10.1016\/j.physbeh.2017.09.014_bb0120","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1002\/mds.26184","article-title":"Spotlight on movement disorders: What optogenetics has to offer","volume":"30","author":"Rossi","year":"2015","journal-title":"Mov. Disord."},{"key":"10.1016\/j.physbeh.2017.09.014_bb0125","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.bbr.2013.07.007","article-title":"Optogenetic cell control in experimental models of neurological disorders","volume":"255","author":"Tonnesen","year":"2013","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.physbeh.2017.09.014_bb0130","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.brainres.2013.01.021","article-title":"New tricks for old dogmas: optogenetic and designer receptor insights for Parkinson's disease","volume":"1511","author":"Vazey","year":"2013","journal-title":"Brain Res."},{"key":"10.1016\/j.physbeh.2017.09.014_bb0135","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.bbacli.2016.09.002","article-title":"Shining light on the head: photobiomodulation for brain disorders","volume":"6","author":"Hamblin","year":"2016","journal-title":"BBA Clin."},{"issue":"Pt A","key":"10.1016\/j.physbeh.2017.09.014_bb0140","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.brainres.2016.07.005","article-title":"Effects of a higher dose of near-infrared light on clinical signs and neuroprotection in a monkey model of Parkinson's disease","volume":"1648","author":"Moro","year":"2016","journal-title":"Brain Res."},{"key":"10.1016\/j.physbeh.2017.09.014_bb0145","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/0091-3057(76)90038-1","article-title":"Intracranial injections of 6-OHDA: comparison of catechoilamine depleting effects of different volumnes and concentrations","volume":"76","author":"Willis","year":"1976","journal-title":"Pharmacol. Biochem. Behav."},{"issue":"1","key":"10.1016\/j.physbeh.2017.09.014_bb0150","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.bbr.2008.04.017","article-title":"Compromised circadian function in Parkinson's disease: enucleation augments disease severity in the unilateral model","volume":"193","author":"Willis","year":"2008","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.physbeh.2017.09.014_bb0155","series-title":"Stereotaxic Atlas of the Rat Brain","author":"Pelligrino","year":"1979"},{"issue":"2","key":"10.1016\/j.physbeh.2017.09.014_bb0160","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/0091-3057(76)90038-1","article-title":"Intracranial injections of 6-OHDA. Comparison of catecholamine-depleting effects of different volumes and concentrations","volume":"5","author":"Willis","year":"1976","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.physbeh.2017.09.014_bb0165","doi-asserted-by":"crossref","first-page":"3921","DOI":"10.1038\/srep03921","article-title":"Parkinson's disease, lights and melanocytes: looking beyond the retina","volume":"4","author":"Willis","year":"2014","journal-title":"Sci Rep"},{"key":"10.1016\/j.physbeh.2017.09.014_bb0170","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/0031-9384(69)90166-8","article-title":"The effect of diencephalic lesions on food intake and motor activity","volume":"4","author":"Balagura","year":"1969","journal-title":"Physiol. Behav."},{"issue":"3","key":"10.1016\/j.physbeh.2017.09.014_bb0175","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1002\/mds.26509","article-title":"Circadian system - a novel diagnostic and therapeutic target in Parkinson's disease?","volume":"31","author":"Videnovic","year":"2016","journal-title":"Mov. Disord."},{"issue":"1","key":"10.1016\/j.physbeh.2017.09.014_bb0180","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.bbr.2004.11.030","article-title":"The therapeutic effects of dopamine replacement therapy and its psychiatric side effects are mediated by pineal function","volume":"160","author":"Willis","year":"2005","journal-title":"Behav. Brain Res."},{"issue":"24","key":"10.1016\/j.physbeh.2017.09.014_bb0185","doi-asserted-by":"crossref","first-page":"3509","DOI":"10.1016\/S0042-6989(97)00129-6","article-title":"Neurobiology of retinal dopamine in relation to degenerative states of the tissue","volume":"37","author":"Djamgoz","year":"1997","journal-title":"Vis. Res."},{"issue":"10","key":"10.1016\/j.physbeh.2017.09.014_bb0190","doi-asserted-by":"crossref","first-page":"2587","DOI":"10.1021\/ja01543a060","article-title":"Isolation of melatonin, the pineal gland factor that lightens melanocytes","volume":"80","author":"Lerner","year":"1958","journal-title":"J. Am. Chem. Soc."},{"issue":"2","key":"10.1016\/j.physbeh.2017.09.014_bb0195","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/0361-9230(90)90208-H","article-title":"The influence of striatum on the substantia nigra: a study using the spreading depression technique","volume":"24","author":"Albe-Fessard","year":"1990","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.physbeh.2017.09.014_bb0200","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.brainres.2013.06.016","article-title":"Oxygen and glucose deprivation (OGD)-induced spreading depression in the Substantia Nigra","volume":"1527","author":"Karunasinghe","year":"2013","journal-title":"Brain Res."},{"issue":"1","key":"10.1016\/j.physbeh.2017.09.014_bb0205","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.expneurol.2005.07.005","article-title":"Spreading depression in the cortex differently modulates dopamine release in rat mesolimbic and nigrostriatal terminal fields","volume":"196","author":"Yavich","year":"2005","journal-title":"Exp. Neurol."},{"issue":"2","key":"10.1016\/j.physbeh.2017.09.014_bb0210","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1111\/j.1749-6632.1969.tb12923.x","article-title":"Stages of recovery and development of lateral hypothalamic control of food and water intaker","volume":"157","author":"Teitelbaum","year":"1969","journal-title":"Ann. N. Y. Acad. Sci."},{"issue":"3","key":"10.1016\/j.physbeh.2017.09.014_bb0215","first-page":"355","article-title":"The influence of cortical and thalamic spreading depression on feeding bahavior of rats wih lateral hypothalamic lesions","volume":"27","author":"Balinska","year":"1967","journal-title":"Acta Biol. Exp. (Warsz)"},{"issue":"3653","key":"10.1016\/j.physbeh.2017.09.014_bb0220","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1126\/science.147.3653.61","article-title":"Spreading depression and recovery from lateral hypothalamic damage","volume":"147","author":"Teitelbaum","year":"1965","journal-title":"Science (New York, N.Y.)"},{"issue":"6","key":"10.1016\/j.physbeh.2017.09.014_bb0225","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1016\/0091-3057(78)90365-9","article-title":"Effects of nigro-striatal 6-OHDA lesions on turning elicited by cortical spreading depression","volume":"9","author":"Huston","year":"1978","journal-title":"Pharmacol. Biochem. Behav."},{"issue":"1 Suppl","key":"10.1016\/j.physbeh.2017.09.014_bb0230","first-page":"15","article-title":"Direct fiber connections between the frontal cortex and the hypothalamus in the rat: an electron microscope study","volume":"3","author":"Yamamoto","year":"1975","journal-title":"Pharmacol. Biochem. Behav."},{"issue":"1","key":"10.1016\/j.physbeh.2017.09.014_bb0235","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1097\/00002826-200401000-00009","article-title":"Dopaminergic hypersensitivity in patients with Parkinson disease and migraine","volume":"27","author":"Cubo","year":"2004","journal-title":"Clin. Neuropharmacol."},{"issue":"14","key":"10.1016\/j.physbeh.2017.09.014_bb0240","doi-asserted-by":"crossref","first-page":"1316","DOI":"10.1177\/0333102416630577","article-title":"Migraine is related to an increased risk of Parkinson's disease: a population-based, propensity score-matched, longitudinal follow-up study","volume":"36","author":"Wang","year":"2016","journal-title":"Cephalalgia"},{"issue":"8","key":"10.1016\/j.physbeh.2017.09.014_bb0245","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1111\/j.1468-2982.2000.00123.x","article-title":"Dopamine and migraine: does Parkinson's disease modify migraine course?","volume":"20","author":"Barbanti","year":"2000","journal-title":"Cephalalgia"},{"issue":"8","key":"10.1016\/j.physbeh.2017.09.014_bb0250","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1177\/0333102413515344","article-title":"Increased susceptibility to cortical spreading depression in an animal model of medication-overuse headache","volume":"34","author":"Green","year":"2014","journal-title":"Cephalalgia"},{"issue":"5","key":"10.1016\/j.physbeh.2017.09.014_bb0255","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1016\/j.pharep.2016.05.001","article-title":"Involvement of CGRP receptors in retinal spreading depression","volume":"68","author":"Wang","year":"2016","journal-title":"Pharmacol. Rep."},{"issue":"4","key":"10.1016\/j.physbeh.2017.09.014_bb0260","first-page":"405","article-title":"Effect of cortical spreading depression on spontaneous firing activities of STN neurones in rats","volume":"22","author":"Liu","year":"2006","journal-title":"Zhongguo Ying Yong Sheng Li Xue Za Zhi"},{"issue":"5","key":"10.1016\/j.physbeh.2017.09.014_bb0265","doi-asserted-by":"crossref","first-page":"1641","DOI":"10.1177\/0271678X16645113","article-title":"Optogenetic induction of cortical spreading depression in anesthetized and freely behaving mice","volume":"37","author":"Houben","year":"2017","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1016\/j.physbeh.2017.09.014_bb0270","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.smrv.2014.06.005","article-title":"Diurnal and twenty-four hour patterning of human diseases: acute and chronic common and uncommon medical conditions","volume":"21","author":"Smolensky","year":"2015","journal-title":"Sleep Med. Rev."},{"key":"10.1016\/j.physbeh.2017.09.014_bb0275","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1037\/h0039285","article-title":"The lateral hypothalamic syndrome: recovery of feeding and drinking after lateral hypothalamic lesions","volume":"69","author":"Teitelbaum","year":"1962","journal-title":"Psychol. Rev."},{"key":"10.1016\/j.physbeh.2017.09.014_bb0280","article-title":"Timed light therapy for sleep and daytime sleepiness associated with Parkinson disease: a randomized clinical trial","volume":"20","author":"Videnovic","year":"2017","journal-title":"JAMA Neurol."},{"key":"10.1016\/j.physbeh.2017.09.014_bb0285","doi-asserted-by":"crossref","first-page":"723","DOI":"10.2147\/NDT.S113998","article-title":"The role of deep brain stimulation in Parkinson's disease: an overview and update on new developments","volume":"13","author":"Fang","year":"2017","journal-title":"Neuropsychiatr. Dis. Treat."},{"issue":"1","key":"10.1016\/j.physbeh.2017.09.014_bb0290","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/0304-3940(83)90122-2","article-title":"Ipsilateral projections to the terminal nuclei of the accessory optic system in the albino rat","volume":"43","author":"Wree","year":"1983","journal-title":"Neurosci. Lett."},{"issue":"2","key":"10.1016\/j.physbeh.2017.09.014_bb0295","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/0006-8993(80)91070-7","article-title":"Cortical activity and sleep in the rat lateral hypothalamic syndrome","volume":"185","author":"Danguir","year":"1980","journal-title":"Brain Res."},{"issue":"5","key":"10.1016\/j.physbeh.2017.09.014_bb0300","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1007\/BF01959946","article-title":"Melatonin modulates apomorphine-induced rotational behaviour","volume":"47","author":"Burton","year":"1991","journal-title":"Experientia"},{"key":"10.1016\/j.physbeh.2017.09.014_bb0305","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.brainres.2008.03.083","article-title":"Intraocular microinjections repair experimental Parkinson's disease","volume":"1217","author":"Willis","year":"2008","journal-title":"Brain Res."},{"issue":"3","key":"10.1016\/j.physbeh.2017.09.014_bb0310","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/j.pbb.2004.08.011","article-title":"Recovery of experimental Parkinson's disease with the melatonin analogues ML-23 and S-20928 in a chronic, bilateral 6-OHDA model: a new mechanism involving antagonism of the melatonin receptor","volume":"79","author":"Willis","year":"2004","journal-title":"Pharmacol. Biochem. Behav."},{"issue":"6","key":"10.1016\/j.physbeh.2017.09.014_bb0315","doi-asserted-by":"crossref","first-page":"741","DOI":"10.3109\/07420528.2012.762011","article-title":"Lack of long-term changes in circadian, locomotor, and cognitive functions in acute and chronic MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) mouse models of Parkinson's disease","volume":"30","author":"Fifel","year":"2013","journal-title":"Chronobiol. Int."},{"issue":"1","key":"10.1016\/j.physbeh.2017.09.014_bb0320","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0086240","article-title":"Alteration of daily and circadian rhythms following dopamine depletion in MPTP treated non-human primates","volume":"9","author":"Fifel","year":"2014","journal-title":"PLoS One"},{"issue":"8","key":"10.1016\/j.physbeh.2017.09.014_bb0325","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1016\/j.jocn.2010.08.043","article-title":"Neuromelanin magnetic resonance imaging of nigral volume loss in patients with Parkinson's disease","volume":"18","author":"Kashihara","year":"2011","journal-title":"J. Clin. Neurosci."},{"key":"10.1016\/j.physbeh.2017.09.014_bb0330","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.brainres.2017.02.026","article-title":"Fluorescent light induces neurodegeneration in the rodent nigrostriatal system but near infrared LED light does not","volume":"1662","author":"Romeo","year":"2017","journal-title":"Brain Res."},{"key":"10.1016\/j.physbeh.2017.09.014_bb0335","first-page":"1","article-title":"Studies on the prevalence of paralysis agitans by tracer methodology","volume":"112","author":"de Pedro Cuesta","year":"1987","journal-title":"Acta Neurol. Scand. Suppl."},{"issue":"5","key":"10.1016\/j.physbeh.2017.09.014_bb0340","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1111\/j.1600-0404.1991.tb04974.x","article-title":"Parkinson's disease incidence: magnitude, comparability, time trends","volume":"84","author":"de Pedro-Cuesta","year":"1991","journal-title":"Acta Neurol. Scand."},{"issue":"8","key":"10.1016\/j.physbeh.2017.09.014_bb0345","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1093\/aje\/kwj096","article-title":"A prospective study of night shift work, sleep duration, and risk of Parkinson's disease","volume":"163","author":"Chen","year":"2006","journal-title":"Am. J. Epidemiol."},{"issue":"11","key":"10.1016\/j.physbeh.2017.09.014_bb0350","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD011269.pub2","article-title":"Light therapy for preventing seasonal affective disorder","volume":"08","author":"Nussbaumer","year":"2015","journal-title":"Cochrane Database Syst. Rev."},{"issue":"1","key":"10.1016\/j.physbeh.2017.09.014_bb0355","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1001\/archpsyc.1984.01790120076010","article-title":"Seasonal affective disorder. A description of the syndrome and preliminary findings with light therapy","volume":"41","author":"Rosenthal","year":"1984","journal-title":"Arch. Gen. Psychiatry"},{"issue":"7","key":"10.1016\/j.physbeh.2017.09.014_bb0360","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1080\/01612840591008410","article-title":"Effects of light therapy on sleep, mood, and temperature in women with nonseasonal major depression","volume":"26","author":"McEnany","year":"2005","journal-title":"Issues in Ment. Health Nurs."},{"issue":"8","key":"10.1016\/j.physbeh.2017.09.014_bb0365","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1017\/S1092852900019611","article-title":"Light therapy for seasonal and nonseasonal depression: efficacy, protocol, safety, and side effects","volume":"10","author":"Terman","year":"2005","journal-title":"CNS Spectr."},{"issue":"4","key":"10.1016\/j.physbeh.2017.09.014_bb0370","doi-asserted-by":"crossref","first-page":"403","DOI":"10.3233\/THC-1996-4405","article-title":"Bright light therapy in focus: lamp emission spectra and ocular safety","volume":"4","author":"Reme","year":"1996","journal-title":"Technol. Health Care"},{"issue":"6","key":"10.1016\/j.physbeh.2017.09.014_bb0375","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/j.smrv.2007.06.003","article-title":"Evolving applications of light therapy","volume":"11","author":"Terman","year":"2007","journal-title":"Sleep Med. Rev."},{"issue":"2","key":"10.1016\/j.physbeh.2017.09.014_bb0380","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/S0002-9394(14)73874-7","article-title":"Ophthalmologic examination of patients with seasonal affective disorder, before and after bright light therapy","volume":"119","author":"Gallin","year":"1995","journal-title":"Am J. Ophthalmol."},{"issue":"1","key":"10.1016\/j.physbeh.2017.09.014_bb0385","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1177\/074873049100600105","article-title":"The visual input stage of the mammalian circadian pacemaking system: II. The effect of light and drugs on retinal function","volume":"6","author":"Terman","year":"1991","journal-title":"J. Biol. Rhythm."},{"issue":"4","key":"10.1016\/j.physbeh.2017.09.014_bb0390","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1111\/j.1751-1097.1979.tb07759.x","article-title":"Sensitivity of the retina to radiation damage as a function of wavelength","volume":"29","author":"Ham","year":"1979","journal-title":"Photochem. Photobiol."},{"issue":"6","key":"10.1016\/j.physbeh.2017.09.014_bb0395","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1016\/0002-9394(79)90413-6","article-title":"Retinal damage from light","volume":"88","author":"Hochheimer","year":"1979","journal-title":"Am J. Ophthalmol."},{"issue":"2","key":"10.1016\/j.physbeh.2017.09.014_bb0400","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/0006-8993(93)91748-H","article-title":"Rod outer segment disk shedding in rats with lesions of the superchiamatic nucleus","volume":"605","author":"Terman","year":"1993","journal-title":"Brain Res."},{"issue":"324","key":"10.1016\/j.physbeh.2017.09.014_bb0405","first-page":"1","article-title":"Neurochemical systems of the retina involved in the control of movement","volume":"8","author":"Willis","year":"2017","journal-title":"Front. Neurol."},{"issue":"10","key":"10.1016\/j.physbeh.2017.09.014_bb0410","doi-asserted-by":"crossref","first-page":"1495","DOI":"10.1002\/mds.21542","article-title":"Bright light therapy in Parkinson's disease: a pilot study","volume":"22","author":"Paus","year":"2007","journal-title":"Mov. Disord."},{"issue":"3","key":"10.1016\/j.physbeh.2017.09.014_bb0415","first-page":"63","article-title":"The phototherapy of parkinsonism patients","volume":"96","author":"Artemenko","year":"1996","journal-title":"Zh. Nevrol. Psikhiatr. Im. SS Korsakova"},{"key":"10.1016\/j.physbeh.2017.09.014_bb0420","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/j.neuropharm.2016.04.001","article-title":"Muscarinic acetylcholine receptor-mediated stimulation of retinal ganglion cell photoreceptors","volume":"108","author":"Sodhi","year":"2016","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.physbeh.2017.09.014_bb0425","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.brainres.2017.02.026","article-title":"Fluorescent light induced neurodegeneration in the rodent nigristriatal system but near infrared light does not. Brain research","volume":"1662","author":"Romeo","year":"2017","journal-title":"Brain Res. Rev."},{"issue":"4","key":"10.1016\/j.physbeh.2017.09.014_bb0430","doi-asserted-by":"crossref","first-page":"574","DOI":"10.4103\/1673-5374.205092","article-title":"Why and how does light therapy offer neuroprotection in Parkinson's disease?","volume":"12","author":"Mitrofanis","year":"2017","journal-title":"Neural Regen. Res."}],"container-title":["Physiology &amp; Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0031938417303001?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0031938417303001?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,6,27]],"date-time":"2024-06-27T00:22:10Z","timestamp":1719447730000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0031938417303001"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,12]]},"references-count":86,"alternative-id":["S0031938417303001"],"URL":"https:\/\/doi.org\/10.1016\/j.physbeh.2017.09.014","relation":{},"ISSN":["0031-9384"],"issn-type":[{"value":"0031-9384","type":"print"}],"subject":[],"published":{"date-parts":[[2017,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The effect of directed photic stimulation of the pineal on experimental Parkinson's disease","name":"articletitle","label":"Article Title"},{"value":"Physiology & Behavior","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.physbeh.2017.09.014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}