{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,30]],"date-time":"2026-03-30T16:48:23Z","timestamp":1774889303405,"version":"3.50.1"},"reference-count":67,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,10,1]],"date-time":"2018-10-01T00:00:00Z","timestamp":1538352000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,10,1]],"date-time":"2018-10-01T00:00:00Z","timestamp":1538352000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"Aomori university"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Physiology & Behavior"],"published-print":{"date-parts":[[2018,10]]},"DOI":"10.1016\/j.physbeh.2018.07.007","type":"journal-article","created":{"date-parts":[[2018,7,4]],"date-time":"2018-07-04T23:19:58Z","timestamp":1530746398000},"page":"505-514","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":22,"special_numbering":"C","title":["Monoamine system disruption induces functional somatic syndromes associated symptomatology in mice"],"prefix":"10.1016","volume":"194","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3264-8808","authenticated-orcid":false,"given":"Yukinori","family":"Nagakura","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nana","family":"Ohsaka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryutarou","family":"Azuma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saeri","family":"Takahashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuuka","family":"Takebayashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saori","family":"Kawasaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuhei","family":"Murai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masaya","family":"Miwa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroko","family":"Saito","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.physbeh.2018.07.007_bb0005","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.7326\/0003-4819-71-5-1013","article-title":"Functional or organic? A pointless question","volume":"71","author":"Lipkin","year":"1969","journal-title":"Ann. Intern. Med."},{"key":"10.1016\/j.physbeh.2018.07.007_bb0010","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1007\/BF02598318","article-title":"Somatization disorder: defining its role in clinical medicine","volume":"6","author":"Smith","year":"1991","journal-title":"J. Gen. Intern. Med."},{"key":"10.1016\/j.physbeh.2018.07.007_bb0015","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1002\/acr.20140","article-title":"The American College of Rheumatology preliminary diagnostic criteria for fibromyalgia and measurement of symptom severity","volume":"62","author":"Wolfe","year":"2010","journal-title":"Arthritis Care Res."},{"key":"10.1016\/j.physbeh.2018.07.007_bb0020","doi-asserted-by":"crossref","first-page":"151","DOI":"10.5056\/jnm16214","article-title":"What is new in Rome IV","volume":"23","author":"Schmulson","year":"2017","journal-title":"J. Neurogastroenterol. Motil."},{"key":"10.1016\/j.physbeh.2018.07.007_bb0025","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1111\/j.1365-2796.2011.02428.x","article-title":"Myalgic encephalomyelitis: international consensus criteria","volume":"270","author":"Carruthers","year":"2011","journal-title":"J. Intern. Med."},{"key":"10.1016\/j.physbeh.2018.07.007_bb0030","doi-asserted-by":"crossref","first-page":"910","DOI":"10.7326\/0003-4819-130-11-199906010-00016","article-title":"Functional somatic syndromes","volume":"130","author":"Barsky","year":"1999","journal-title":"Ann. Intern. Med."},{"key":"10.1016\/j.physbeh.2018.07.007_bb0035","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1016\/S0140-6736(98)08320-2","article-title":"Functional somatic syndromes: one or many?","volume":"354","author":"Wessely","year":"1999","journal-title":"Lancet"},{"key":"10.1016\/j.physbeh.2018.07.007_bb0040","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1097\/PSY.0b013e31815b001a","article-title":"The association or otherwise of the functional somatic syndromes","volume":"69","author":"Kanaan","year":"2007","journal-title":"Psychosom. Med."},{"key":"10.1016\/j.physbeh.2018.07.007_bb0045","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1007\/s11606-007-0140-5","article-title":"Feeling bad in more ways than one: comorbidity patterns of medically unexplained and psychiatric conditions","volume":"22","author":"Schur","year":"2007","journal-title":"J. Gen. Intern. Med."},{"key":"10.1016\/j.physbeh.2018.07.007_bb0050","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1017\/S0033291708003784","article-title":"A population-based twin study of functional somatic syndromes","volume":"39","author":"Kato","year":"2009","journal-title":"Psychol. Med."},{"key":"10.1016\/j.physbeh.2018.07.007_bb0055","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1192\/bjp.bp.108.051813","article-title":"Comparative epidemiology of chronic fatigue syndrome in Brazilian and British primary care: prevalence and recognition","volume":"194","author":"Cho","year":"2009","journal-title":"Br. J. Psychiatry"},{"key":"10.1016\/j.physbeh.2018.07.007_bb0060","doi-asserted-by":"crossref","first-page":"1547","DOI":"10.1001\/jama.2014.3266","article-title":"Fibromyalgia: a clinical review","volume":"311","author":"Clauw","year":"2014","journal-title":"JAMA"},{"key":"10.1016\/j.physbeh.2018.07.007_bb0065","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1001\/jama.2015.0954","article-title":"Irritable bowel syndrome: a clinical review","volume":"313","author":"Chey","year":"2015","journal-title":"JAMA"},{"key":"10.1016\/j.physbeh.2018.07.007_bb0070","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1097\/PSY.0000000000000502","article-title":"Core outcome domains for clinical trials on somatic symptom disorder, bodily distress disorder, and functional somatic syndromes: European network on somatic symptom disorders recommendations","volume":"79","author":"Rief","year":"2017","journal-title":"Psychosom. Med."},{"key":"10.1016\/j.physbeh.2018.07.007_bb0075","doi-asserted-by":"crossref","first-page":"946","DOI":"10.1016\/S0140-6736(07)60159-7","article-title":"Management of functional somatic syndromes","volume":"369","author":"Henningsen","year":"2007","journal-title":"Lancet"},{"key":"10.1016\/j.physbeh.2018.07.007_bb0080","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1097\/PSY.0b013e31815b00c4","article-title":"Efficacy of treatment for somatoform disorders: a review of randomized controlled trials","volume":"69","author":"Kroenke","year":"2007","journal-title":"Psychosom. Med."},{"key":"10.1016\/j.physbeh.2018.07.007_bb0085","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1097\/YCO.0b013e3282f51254","article-title":"Recent developments in the understanding and management of functional somatic symptoms in primary care","volume":"21","author":"Fink","year":"2008","journal-title":"Curr. Opin. Psychiatry"},{"key":"10.1016\/j.physbeh.2018.07.007_bb0090","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1186\/1472-6963-13-520","article-title":"Patients with unexplained physical symptoms have poorer quality of life and higher costs than other patient groups: a cross-sectional study on burden","volume":"13","author":"Zonneveld","year":"2013","journal-title":"BMC Health Serv. Res."},{"key":"10.1016\/j.physbeh.2018.07.007_bb0095","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.jpsychores.2015.05.004","article-title":"Functional limitations in functional somatic syndromes and well-defined medical diseases. Results from the general population cohort LifeLines","volume":"79","author":"Joustra","year":"2015","journal-title":"J. Psychosom. Res."},{"key":"10.1016\/j.physbeh.2018.07.007_bb0100","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.berh.2015.04.018","article-title":"Update on the genetics of the fibromyalgia syndrome","volume":"29","author":"Ablin","year":"2015","journal-title":"Best Pract. Res. Clin. Rheumatol."},{"key":"10.1016\/j.physbeh.2018.07.007_bb0105","doi-asserted-by":"crossref","first-page":"2967","DOI":"10.1093\/hmg\/ddn195","article-title":"First evidence for an association of a functional variant in the microRNA-510 target site of the serotonin receptor-type 3E gene with diarrhea predominant irritable bowel syndrome","volume":"17","author":"Kapeller","year":"2008","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.physbeh.2018.07.007_bb0110","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1016\/j.psyneuen.2007.11.001","article-title":"Genetic evaluation of the serotonergic system in chronic fatigue syndrome","volume":"33","author":"Smith","year":"2008","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.physbeh.2018.07.007_bb0115","doi-asserted-by":"crossref","first-page":"107","DOI":"10.3109\/09540261.2012.729758","article-title":"Psychopharmacotherapy of somatic symptoms disorders","volume":"25","author":"Somashekar","year":"2013","journal-title":"Int. Rev. Psychiatry"},{"key":"10.1016\/j.physbeh.2018.07.007_bb0120","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1016\/j.jpain.2008.12.008","article-title":"Changes in gray matter density in fibromyalgia: correlation with dopamine metabolism","volume":"10","author":"Wood","year":"2009","journal-title":"J. Pain"},{"key":"10.1016\/j.physbeh.2018.07.007_bb0125","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/j.biopsycho.2013.06.002","article-title":"Norepinephrine and epinephrine responses to physiological and pharmacological stimulation in chronic fatigue syndrome","volume":"94","author":"Strahler","year":"2013","journal-title":"Biol. Psychol."},{"key":"10.1016\/j.physbeh.2018.07.007_bb0130","doi-asserted-by":"crossref","first-page":"52","DOI":"10.3389\/fneur.2015.00052","article-title":"The dopamine imbalance hypothesis of fatigue in multiple sclerosis and other neurological disorders","volume":"6","author":"Dobryakova","year":"2015","journal-title":"Front. Neurol."},{"key":"10.1016\/j.physbeh.2018.07.007_bb0135","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1186\/ar4402","article-title":"Animal models of fibromyalgia","volume":"15","author":"Desantana","year":"2013","journal-title":"Arthritis Res. Ther."},{"key":"10.1016\/j.physbeh.2018.07.007_bb0140","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1080\/24708593.2016.1273986","article-title":"Recent advancements in animal models of fibromyalgia","volume":"23","author":"Nagakura","year":"2015","journal-title":"MYOPAIN"},{"key":"10.1016\/j.physbeh.2018.07.007_bb0145","doi-asserted-by":"crossref","first-page":"15","DOI":"10.3389\/fpsyt.2015.00015","article-title":"Stress-induced visceral pain: toward animal models of irritable-bowel syndrome and associated comorbidities","volume":"6","author":"Moloney","year":"2015","journal-title":"Front. Psychiatry"},{"key":"10.1016\/j.physbeh.2018.07.007_bb0150","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.pain.2009.05.024","article-title":"Biogenic amine depletion causes chronic muscular pain and tactile allodynia accompanied by depression: a putative animal model of fibromyalgia","volume":"146","author":"Nagakura","year":"2009","journal-title":"Pain"},{"key":"10.1016\/j.physbeh.2018.07.007_bb0155","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.pbb.2013.04.007","article-title":"Systemic administration of 5-HT(2C) receptor agonists attenuates muscular hyperalgesia in reserpine-induced myalgia model","volume":"108","author":"Ogino","year":"2013","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.physbeh.2018.07.007_bb0160","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1016\/j.physbeh.2015.07.033","article-title":"Depressive-like symptoms in a reserpine-induced model of fibromyalgia in rats","volume":"151","author":"Blasco-Serra","year":"2015","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.physbeh.2018.07.007_bb0165","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1097\/01.j.pain.0000460334.49525.5e","article-title":"Peripheral and spinal mechanisms of nociception in a rat reserpine-induced pain model","volume":"156","author":"Taguchi","year":"2015","journal-title":"Pain"},{"key":"10.1016\/j.physbeh.2018.07.007_bb0170","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.3390\/ijms18071389","article-title":"Oral supplementation of melatonin protects against fibromyalgia-related skeletal muscle alterations in reserpine-induced myalgia rats","volume":"18","author":"Favero","year":"2017","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.physbeh.2018.07.007_bb0175","doi-asserted-by":"crossref","DOI":"10.1038\/srep38325","article-title":"Functional MRI of the reserpine-induced putative rat model of fibromyalgia reveals discriminatory patterns of functional augmentation to acute nociceptive stimuli","volume":"7","author":"Wells","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.physbeh.2018.07.007_bb0180","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.yhbeh.2017.10.011","article-title":"Sex differences and estradiol involvement in hyperalgesia and allodynia in an experimental model of fibromyalgia","volume":"97","author":"Hernandez-Leon","year":"2018","journal-title":"Horm. Behav."},{"key":"10.1016\/j.physbeh.2018.07.007_bb0185","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.ejphar.2018.03.011","article-title":"Effects of pregabalin and duloxetine on neurotransmitters in the dorsal horn of the spinal cord in a rat model of fibromyalgia","volume":"827","author":"Kiso","year":"2018","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.physbeh.2018.07.007_bb0190","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.toxicon.2014.01.015","article-title":"The effects of Ph\u03b11\u03b2, a spider toxin, calcium channel blocker, in a mouse fibromyalgia model","volume":"81","author":"de Souza","year":"2014","journal-title":"Toxicon"},{"key":"10.1016\/j.physbeh.2018.07.007_bb0195","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.neuropharm.2014.05.043","article-title":"Effects of D-series resolvins on behavioral and neurochemical changes in a fibromyalgia-like model in mice","volume":"86","author":"Klein","year":"2014","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.physbeh.2018.07.007_bb0200","first-page":"3191638","article-title":"Coadministration of resveratrol and rice oil mitigates nociception and oxidative state in a mouse fibromyalgia-like model","author":"Klein","year":"2016","journal-title":"Pain Res. Treat."},{"key":"10.1016\/j.physbeh.2018.07.007_bb0205","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1007\/s12017-013-8280-8","article-title":"Attenuation of reserpine-induced pain\/depression dyad by gentiopicroside through downregulation of GluN2B receptors in the amygdala of mice","volume":"16","author":"Liu","year":"2014","journal-title":"NeuroMolecular Med."},{"key":"10.1016\/j.physbeh.2018.07.007_bb0210","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1007\/s11011-013-9404-4","article-title":"Ferulic acid increases pain threshold and ameliorates depression-like behaviors in reserpine-treated mice: behavioral and neurobiological analyses","volume":"28","author":"Xu","year":"2013","journal-title":"Metab. Brain Dis."},{"key":"10.1016\/j.physbeh.2018.07.007_bb0215","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pbio.1000412","article-title":"Improving bioscience research reporting: the ARRIVE guidelines for reporting animal research","volume":"8","author":"Kilkenny","year":"2010","journal-title":"PLoS Biol."},{"key":"10.1016\/j.physbeh.2018.07.007_bb0220","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/0165-0270(94)90144-9","article-title":"Quantitative assessment of tactile allodynia in the rat paw","volume":"53","author":"Chaplan","year":"1994","journal-title":"J. Neurosci. Methods"},{"key":"10.1016\/j.physbeh.2018.07.007_bb0225","doi-asserted-by":"crossref","first-page":"G1266","DOI":"10.1152\/ajpgi.00444.2004","article-title":"Acute colitis induction by oil of mustard results in later development of an IBS-like accelerated upper GI transit in mice","volume":"288","author":"Kimball","year":"2005","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol."},{"key":"10.1016\/j.physbeh.2018.07.007_bb0230","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/0091-3057(92)90539-R","article-title":"Rapid and simultaneous assay of monoamine neurotransmitters and their metabolites in discrete brain areas of mice by HPLC with coulometric detection","volume":"42","author":"Saito","year":"1992","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.physbeh.2018.07.007_bb0235","doi-asserted-by":"crossref","first-page":"1885","DOI":"10.1016\/0016-5085(87)90620-2","article-title":"Altered small bowel motility in irritable bowel syndrome is correlated with symptoms","volume":"92","author":"Kellow","year":"1987","journal-title":"Gastroenterology"},{"key":"10.1016\/j.physbeh.2018.07.007_bb0240","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1136\/gut.48.1.14","article-title":"Impaired transit and tolerance of intestinal gas in the irritable bowel syndrome","volume":"48","author":"Serra","year":"2001","journal-title":"Gut"},{"key":"10.1016\/j.physbeh.2018.07.007_bb0245","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1016\/S0022-3956(97)00039-3","article-title":"Physical activity in chronic fatigue syndrome: assessment and its role in fatigue","volume":"31","author":"Vercoulen","year":"1997","journal-title":"J. Psychiatr. Res."},{"key":"10.1016\/j.physbeh.2018.07.007_bb0250","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/S0022-3999(00)00197-5","article-title":"Identifying physical activity patterns in chronic fatigue syndrome using actigraphic assessment","volume":"49","author":"van der Werf","year":"2000","journal-title":"J. Psychosom. Res."},{"key":"10.1016\/j.physbeh.2018.07.007_bb0255","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/S0022-3565(25)32540-1","article-title":"Effects of reserpine on monoamines and intestinal transit in the rat","volume":"217","author":"Stewart","year":"1981","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.physbeh.2018.07.007_bb0260","doi-asserted-by":"crossref","first-page":"1860","DOI":"10.1016\/j.neuroscience.2010.06.061","article-title":"Reserpine causes biphasic nociceptive sensitivity alteration in conjunction with brain biogenic amine tones in rats","volume":"169","author":"Oe","year":"2010","journal-title":"Neuroscience"},{"key":"10.1016\/j.physbeh.2018.07.007_bb0265","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1111\/j.1476-5381.1971.tb07118.x","article-title":"3,4-dihydroxyphenylacetic acid and 4-hydroxy-3-methoxyphenylacetic acid in the mouse striatum: a reflection of intra- and extra-neuronal metabolism of dopamine?","volume":"42","author":"Roffler-Tarlov","year":"1971","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.physbeh.2018.07.007_bb0270","doi-asserted-by":"crossref","first-page":"2841","DOI":"10.1016\/j.lfs.2004.08.004","article-title":"Hyperforin depletes synaptic vesicles content and induces compartmental redistribution of nerve ending monoamines","volume":"75","author":"Roz","year":"2004","journal-title":"Life Sci."},{"key":"10.1016\/j.physbeh.2018.07.007_bb0275","doi-asserted-by":"crossref","first-page":"1803","DOI":"10.1097\/j.pain.0000000000000240","article-title":"Diffuse noxious inhibitory controls and nerve injury: restoring an imbalance between descending monoamine inhibitions and facilitations","volume":"156","author":"Bannister","year":"2015","journal-title":"Pain"},{"key":"10.1016\/j.physbeh.2018.07.007_bb0280","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1097\/AJP.0b013e318183cfa4","article-title":"The deficit of pain inhibition in fibromyalgia is more pronounced in patients with comorbid depressive symptoms","volume":"25","author":"de Souza","year":"2009","journal-title":"Clin. J. Pain"},{"key":"10.1016\/j.physbeh.2018.07.007_bb0290","doi-asserted-by":"crossref","first-page":"4071","DOI":"10.2174\/138161206778743637","article-title":"CRF1 receptors as a therapeutic target for irritable bowel syndrome","volume":"12","author":"Martinez","year":"2006","journal-title":"Curr. Pharm. Des."},{"key":"10.1016\/j.physbeh.2018.07.007_bb0295","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1053\/j.gastro.2006.11.002","article-title":"The serotonin signaling system: from basic understanding to drug development for functional GI disorders","volume":"132","author":"Gershon","year":"2007","journal-title":"Gastroenterology"},{"key":"10.1016\/j.physbeh.2018.07.007_bb0300","doi-asserted-by":"crossref","first-page":"1651","DOI":"10.1053\/j.gastro.2003.09.028","article-title":"Relative importance of enterochromaffin cell hyperplasia, anxiety, and depression in postinfectious IBS","volume":"125","author":"Dunlop","year":"2003","journal-title":"Gastroenterology"},{"key":"10.1016\/j.physbeh.2018.07.007_bb0305","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/S1542-3565(04)00726-8","article-title":"Abnormalities of 5-hydroxytryptamine metabolism in irritable bowel syndrome","volume":"3","author":"Dunlop","year":"2005","journal-title":"Clin. Gastroenterol. Hepatol."},{"key":"10.1016\/j.physbeh.2018.07.007_bb0310","doi-asserted-by":"crossref","first-page":"1434","DOI":"10.1053\/j.gastro.2011.01.052","article-title":"Impaired uptake of serotonin by platelets from patients with irritable bowel syndrome correlates with duodenal immune activation","volume":"140","author":"Foley","year":"2011","journal-title":"Gastroenterology"},{"key":"10.1016\/j.physbeh.2018.07.007_bb0315","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1111\/apt.13459","article-title":"Alterations in serotonin metabolism in the irritable bowel syndrome","volume":"43","author":"Thijssen","year":"2016","journal-title":"Aliment. Pharmacol. Ther."},{"key":"10.1016\/j.physbeh.2018.07.007_bb0320","doi-asserted-by":"crossref","first-page":"15141","DOI":"10.1038\/s41598-017-15548-6","article-title":"Induction of glucose uptake in skeletal muscle by central leptin is mediated by muscle \u03b22-adrenergic receptor but not by AMPK","volume":"7","author":"Shiuchi","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.physbeh.2018.07.007_bb0325","doi-asserted-by":"crossref","first-page":"S17","DOI":"10.1038\/ijosup.2014.6","article-title":"Coordinate control of adipose 'browning' and energy expenditure by \u03b2-adrenergic and natriuretic peptide signalling","volume":"4","author":"Collins","year":"2014","journal-title":"Int. J. Obes."},{"key":"10.1016\/j.physbeh.2018.07.007_bb0330","doi-asserted-by":"crossref","first-page":"7634","DOI":"10.1074\/jbc.M114.592519","article-title":"Catecholamine stress hormones regulate cellular iron homeostasis by a posttranscriptional mechanism mediated by iron regulatory protein: implication in energy homeostasis","volume":"290","author":"Tapryal","year":"2015","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.physbeh.2018.07.007_bb0335","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1016\/S0026-895X(25)12427-9","article-title":"Inhibition by serotonin of amino acid release and protein degradation in skeletal muscle","volume":"13","author":"Garber","year":"1977","journal-title":"Mol. Pharmacol."},{"key":"10.1016\/j.physbeh.2018.07.007_bb0340","doi-asserted-by":"crossref","first-page":"14825","DOI":"10.1074\/jbc.272.23.14825","article-title":"Identification and localization of a skeletal muscle serotonin 5-HT2A receptor coupled to the Jak\/STAT pathway","volume":"272","author":"Guilliett-Deniau","year":"1997","journal-title":"J. Biol. Chem."}],"container-title":["Physiology & Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0031938418304487?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0031938418304487?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T18:11:20Z","timestamp":1758478280000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0031938418304487"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10]]},"references-count":67,"alternative-id":["S0031938418304487"],"URL":"https:\/\/doi.org\/10.1016\/j.physbeh.2018.07.007","relation":{},"ISSN":["0031-9384"],"issn-type":[{"value":"0031-9384","type":"print"}],"subject":[],"published":{"date-parts":[[2018,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Monoamine system disruption induces functional somatic syndromes associated symptomatology in mice","name":"articletitle","label":"Article Title"},{"value":"Physiology & Behavior","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.physbeh.2018.07.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}