{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T15:31:05Z","timestamp":1759073465543,"version":"3.44.0"},"reference-count":42,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100005716","name":"Babol University of Medical Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005716","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Physiology &amp; Behavior"],"published-print":{"date-parts":[[2021,2]]},"DOI":"10.1016\/j.physbeh.2020.113214","type":"journal-article","created":{"date-parts":[[2020,10,20]],"date-time":"2020-10-20T01:03:37Z","timestamp":1603155817000},"page":"113214","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"special_numbering":"C","title":["Role of D1- and D2-like dopamine receptors within the dentate gyrus in antinociception induced by chemical stimulation of the lateral hypothalamus in an animal model of acute pain"],"prefix":"10.1016","volume":"229","author":[{"given":"Hossein","family":"Khaleghzadeh-Ahangar","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mina","family":"Rashvand","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abbas","family":"Haghparast","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.physbeh.2020.113214_bib0001","doi-asserted-by":"crossref","first-page":"78","DOI":"10.3389\/fncir.2019.00078","article-title":"VTA GABA neurons at the interface of stress and reward","volume":"13","author":"Bouarab","year":"2019","journal-title":"Front. Neural Circuits"},{"key":"10.1016\/j.physbeh.2020.113214_bib0002","doi-asserted-by":"crossref","DOI":"10.1016\/j.physbeh.2019.112595","article-title":"Role of orexin receptors within the dentate gyrus of the hippocampus in antinociception induced by chemical stimulation of the lateral hypothalamus in the tail-flick test as a model of acute pain in rats","volume":"209","author":"Brojeni","year":"2019","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.physbeh.2020.113214_bib0003","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1016\/S0091-3057(99)00145-8","article-title":"Effects of formalin pain on hippocampal c-Fos expression in male and female rats","volume":"64","author":"Ceccarelli","year":"1999","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.physbeh.2020.113214_bib0004","series-title":"Limbic Mechanisms","first-page":"47","article-title":"Synapse formation and plasticity in the developing dentate gyrus","author":"Cotman","year":"1978"},{"key":"10.1016\/j.physbeh.2020.113214_bib0005","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/S0022-3565(25)03823-6","article-title":"A method for determining loss of pain sensation","volume":"72","author":"D'amour","year":"1941","journal-title":"Pharmacol. Exp. Ther."},{"key":"10.1016\/j.physbeh.2020.113214_bib0006","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1016\/0306-4522(95)00358-4","article-title":"Lateral hypothalamus: site involved in pain modulation","volume":"70","author":"Dafny","year":"1996","journal-title":"Neuroscience"},{"key":"10.1016\/j.physbeh.2020.113214_bib0007","doi-asserted-by":"crossref","first-page":"E5501","DOI":"10.1073\/pnas.1606951113","article-title":"Dopaminergic inputs in the dentate gyrus direct the choice of memory encoding","volume":"113","author":"Du","year":"2016","journal-title":"Natl. Acad Sci."},{"key":"10.1016\/j.physbeh.2020.113214_bib0008","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1097\/FBP.0000000000000277","article-title":"Role of orexin-2 and CB1 receptors within the periaqueductal gray matter in lateral hypothalamic-induced antinociception in rats","volume":"28","author":"Esmaeili","year":"2017","journal-title":"Behav. Pharmacol."},{"key":"10.1016\/j.physbeh.2020.113214_bib0009","doi-asserted-by":"crossref","first-page":"1090","DOI":"10.1002\/ejp.833","article-title":"Differential contribution of orexin receptors within the ventral tegmental area to modulation of persistent inflammatory pain","volume":"20","author":"Ezzatpanah","year":"2016","journal-title":"Eur. J. Pain"},{"key":"10.1016\/j.physbeh.2020.113214_bib0010","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.pbb.2014.12.012","article-title":"Chemical stimulation of the lateral hypothalamus by carbachol attenuated the formalin-induced pain behaviors in rats","volume":"129","author":"Ezzatpanah","year":"2015","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.physbeh.2020.113214_bib0011","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1007\/s11064-020-02957-9","article-title":"Involvement of orexinergic system within the nucleus accumbens in pain modulatory role of the lateral hypothalamus in orofacial pain model","volume":"45","author":"Haghparast","year":"2020","journal-title":"Neurochem. Res."},{"key":"10.1016\/j.physbeh.2020.113214_bib0012","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/j.peptides.2017.10.006","article-title":"Blockade of the orexin receptors in the CA1 region of hippocampus decreased the lateral hypothalamic-induced antinociceptive responses in the model of orofacial formalin test in the rats","volume":"99","author":"Haghparast","year":"2018","journal-title":"Peptides"},{"key":"10.1016\/j.physbeh.2020.113214_bib0013","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.bbr.2011.01.045","article-title":"Changes in phosphorylation of CREB, ERK, and c-fos induction in rat ventral tegmental area, hippocampus and prefrontal cortex after conditioned place preference induced by chemical stimulation of lateral hypothalamus","volume":"220","author":"Haghparast","year":"2011","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.physbeh.2020.113214_bib0014","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1093\/brain\/101.1.83","article-title":"Mental phenomena evoked by electrical stimulation of the human hippocampal formation and amygdala","volume":"101","author":"Halgren","year":"1978","journal-title":"Brain"},{"key":"10.1016\/j.physbeh.2020.113214_bib0015","first-page":"851","article-title":"Intra-accumbal orexin-1 receptors are involved in antinociception induced by stimulation of the lateral hypothalamus in the formalin test as an animal model of persistent inflammatory pain","volume":"15","author":"Jahangirvand","year":"2016","journal-title":"Iran J Pharm Res"},{"key":"10.1016\/j.physbeh.2020.113214_bib0016","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.bbr.2018.07.018","article-title":"Involvement of D1-and D2-like dopamine receptors in the dentate gyrus in the acquisition, expression, and extinction of the morphine-induced conditioned place preference in rats","volume":"353","author":"Katebi","year":"2018","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.physbeh.2020.113214_bib0017","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1111\/ejn.13364","article-title":"On the properties of identified dopaminergic neurons in the mouse substantia nigra and ventral tegmental area","volume":"45","author":"Krashia","year":"2017","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.physbeh.2020.113214_bib0018","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1152\/jn.1998.80.1.113","article-title":"Substance P enhances NMDA channel function in hippocampal dentate gyrus granule cells","volume":"80","author":"Lieberman","year":"1998","journal-title":"J. Neurophysiol."},{"key":"10.1016\/j.physbeh.2020.113214_bib0019","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1007\/s12264-009-0905-4","article-title":"Roles of the hippocampal formation in pain information processing","volume":"25","author":"Liu","year":"2009","journal-title":"Neurosci. Bull."},{"key":"10.1016\/j.physbeh.2020.113214_bib0020","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/S0006-8993(99)02396-3","article-title":"The involvement of dopamine in nociception: the role of D1 and D2 receptors in the dorsolateral striatum","volume":"855","author":"Magnusson","year":"2000","journal-title":"Brain Res."},{"key":"10.1016\/j.physbeh.2020.113214_bib0021","doi-asserted-by":"crossref","first-page":"1449","DOI":"10.2147\/JPR.S255250","article-title":"Role of dopaminergic receptors within the ventral tegmental area in antinociception induced by chemical stimulation of the lateral hypothalamus in an animal model of orofacial pain","volume":"13","author":"Matini","year":"2020","journal-title":"J. Pain Res."},{"key":"10.1016\/j.physbeh.2020.113214_bib0022","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1006\/exnr.2001.7777","article-title":"Blocking NMDA receptors in the hippocampal dentate gyrus with AP5 produces analgesia in the formalin pain test","volume":"172","author":"McKenna","year":"2001","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.physbeh.2020.113214_bib0023","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/0304-3959(92)90195-H","article-title":"Analgesia produced by lidocaine microinjection into the dentate gyms","volume":"49","author":"McKenna","year":"1992","journal-title":"Pain"},{"key":"10.1016\/j.physbeh.2020.113214_bib0024","first-page":"423","article-title":"Sensory, motivational, and central control determinants of pain: a new conceptual model","volume":"1","author":"Melzack","year":"1968","journal-title":"The Skin Senses"},{"key":"10.1016\/j.physbeh.2020.113214_bib0025","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.neulet.2015.05.047","article-title":"Blockade of D1-like dopamine receptors within the ventral tegmental area and nucleus accumbens attenuates antinociceptive responses induced by chemical stimulation of the lateral hypothalamus","volume":"599","author":"Moradi","year":"2015","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.physbeh.2020.113214_bib0026","doi-asserted-by":"crossref","unstructured":"Ntamati NR, L\u00fcscher C (2016) VTA projection neurons releasing GABA and glutamate in the dentate gyrus. eneuro 3.","DOI":"10.1523\/ENEURO.0137-16.2016"},{"key":"10.1016\/j.physbeh.2020.113214_bib0027","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1254\/jphs.FP0071986","article-title":"Cholinergic regulation of orexin\/hypocretin neurons through M3 muscarinic receptor in mice","volume":"106","author":"Ohno","year":"2008","journal-title":"J. Pharmacol. Sci."},{"year":"2006","series-title":"The rat brain in stereotaxic coordinates: hard cover edition","author":"Paxinos","key":"10.1016\/j.physbeh.2020.113214_bib0028"},{"key":"10.1016\/j.physbeh.2020.113214_bib0029","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.physbeh.2017.12.036","article-title":"Role of dorsal hippocampal orexin-1 receptors in modulation of antinociception induced by chemical stimulation of the lateral hypothalamus","volume":"185","author":"Pourreza","year":"2018","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.physbeh.2020.113214_bib0030","doi-asserted-by":"crossref","DOI":"10.1016\/j.brainres.2020.146759","article-title":"Role of intra-hippocampal dopamine receptors in the antinociceptive responses induced by chemical stimulation of the lateral hypothalamus in animal model of acute pain","author":"Rezaee","year":"2020","journal-title":"Brain Res."},{"key":"10.1016\/j.physbeh.2020.113214_bib0031","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/j.neuron.2005.03.010","article-title":"Input of orexin\/hypocretin neurons revealed by a genetically encoded tracer in mice","volume":"46","author":"Sakurai","year":"2005","journal-title":"Neuron"},{"key":"10.1016\/j.physbeh.2020.113214_bib0032","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/0304-3940(80)90314-6","article-title":"Origin of dopaminergic innervation of the rat hippocampal formation","volume":"18","author":"Scatton","year":"1980","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.physbeh.2020.113214_bib0033","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.physbeh.2018.01.020","article-title":"Role of D1-and D2-like dopaminergic receptors in the nucleus accumbens in modulation of formalin-induced orofacial pain: Involvement of lateral hypothalamus","volume":"188","author":"Shafiei","year":"2018","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.physbeh.2020.113214_bib0034","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.pbb.2013.10.029","article-title":"Involvement of dopamine receptors within the dorsal hippocampus in suppression of the formalin-induced orofacial pain","volume":"114","author":"Shamsizadeh","year":"2013","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.physbeh.2020.113214_bib0035","first-page":"1","article-title":"Obligatory roles of dopamine D1 receptors in the dentate gyrus in antidepressant actions of a selective serotonin reuptake inhibitor, fluoxetine","author":"Shuto","year":"2018","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.physbeh.2020.113214_bib0036","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.1002\/ejp.1029","article-title":"Nucleus accumbens dopamine receptors mediate hypothalamus induced antinociception in the rat formalin test","volume":"21","author":"Siahposht Khachaki","year":"2017","journal-title":"Eur. J. Pain"},{"key":"10.1016\/j.physbeh.2020.113214_bib0037","first-page":"391","article-title":"Molecular neurobiology of dopaminergic receptors","volume":"35","author":"Sibley","year":"1993"},{"key":"10.1016\/j.physbeh.2020.113214_bib0038","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.brainresbull.2018.11.010","article-title":"Dopamine in the hippocampal dentate gyrus modulates spatial learning via D1-like receptors","volume":"144","author":"Wang","year":"2019","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.physbeh.2020.113214_bib0039","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1586\/14737175.8.5.781","article-title":"Role of central dopamine in pain and analgesia","volume":"8","author":"Wood","year":"2008","journal-title":"Expert. Rev. Neurother."},{"key":"10.1016\/j.physbeh.2020.113214_bib0040","doi-asserted-by":"crossref","first-page":"3576","DOI":"10.1111\/j.1460-9568.2007.05623.x","article-title":"Fibromyalgia patients show an abnormal dopamine response to pain","volume":"25","author":"Wood","year":"2007","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.physbeh.2020.113214_bib0041","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1038\/s41593-018-0288-9","article-title":"GABA and glutamate neurons in the VTA regulate sleep and wakefulness","volume":"22","author":"Yu","year":"2019","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.physbeh.2020.113214_bib0042","doi-asserted-by":"crossref","DOI":"10.1016\/j.brainresbull.2020.06.017","article-title":"Modulatory role of hippocampal dopamine receptors in antinociceptive responses induced by chemical stimulation of the lateral hypothalamus in an animal model of persistent inflammatory pain","author":"Zakeri","year":"2020","journal-title":"Brain Res. Bull."}],"container-title":["Physiology &amp; Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S003193842030528X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S003193842030528X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T18:19:47Z","timestamp":1758478787000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S003193842030528X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2]]},"references-count":42,"alternative-id":["S003193842030528X"],"URL":"https:\/\/doi.org\/10.1016\/j.physbeh.2020.113214","relation":{},"ISSN":["0031-9384"],"issn-type":[{"type":"print","value":"0031-9384"}],"subject":[],"published":{"date-parts":[[2021,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Role of D1- and D2-like dopamine receptors within the dentate gyrus in antinociception induced by chemical stimulation of the lateral hypothalamus in an animal model of acute pain","name":"articletitle","label":"Article Title"},{"value":"Physiology & Behavior","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.physbeh.2020.113214","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"113214"}}