{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,9]],"date-time":"2025-11-09T03:48:10Z","timestamp":1762660090022,"version":"3.44.0"},"reference-count":52,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100000038","name":"Natural Sciences and Engineering Research Council of Canada","doi-asserted-by":"publisher","award":["R2195A01007"],"award-info":[{"award-number":["R2195A01007"]}],"id":[{"id":"10.13039\/501100000038","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Physiology &amp; Behavior"],"published-print":{"date-parts":[[2021,10]]},"DOI":"10.1016\/j.physbeh.2021.113559","type":"journal-article","created":{"date-parts":[[2021,8,17]],"date-time":"2021-08-17T14:45:35Z","timestamp":1629211535000},"page":"113559","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Toxin-induced aversive context conditioning: Assessing active aversive behaviors conditioned to the context of an automated activity monitor"],"prefix":"10.1016","volume":"240","author":[{"given":"Minakshi","family":"Doobay","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shelly K.","family":"Cross-Mellor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deanne T.O.","family":"Wah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Kavaliers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Klaus-Peter","family":"Ossenkopp","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.physbeh.2021.113559_bib0001","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/0301-0082(89)90028-2","article-title":"Area postrema: chemoreceptor circumventricular organ of the medulla oblongata","volume":"32","author":"Borison","year":"1989","journal-title":"Prog. Neurobiol."},{"key":"10.1016\/j.physbeh.2021.113559_bib0002","series-title":"Handbook of Olfaction and Gustation, Third Edition","first-page":"865","article-title":"Conditioned taste aversions","author":"Chambers","year":"2015"},{"key":"10.1016\/j.physbeh.2021.113559_bib0003","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.bbr.2018.05.033","article-title":"Lipopolysaccharide (LPS) induced sickness in adolescent female rats alters the acute-phase response and lithium chloride (LiCl) -induced conditioned place avoidance acquisition, following a homotypic LPS challenge in adulthood","volume":"351","author":"Cloutier","year":"2018","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.physbeh.2021.113559_bib0004","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.pbb.2016.08.006","article-title":"Rodent sex differences in disgust behaviours (anticipatory nausea) conditioned to a context associated with the effects of the toxin LiCl: inhibition of conditioning following immune stimulation with lipopolysaccharide","volume":"152","author":"Cloutier","year":"2016","journal-title":"Pharmacol. Biochem. Behav."},{"issue":"2","key":"10.1016\/j.physbeh.2021.113559_bib0005","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.neulet.2011.07.003","article-title":"Simultaneous conditioning of \u201cgaping\u201d responses and taste avoidance in rats injected with LiCl and saccharin: examining the role of context and taste cues in the rodent model of anticipatory nausea","volume":"502","author":"Cloutier","year":"2011","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.physbeh.2021.113559_bib0006","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.pbb.2018.08.008","article-title":"Conditioned disgust in rats (anticipatory nausea) to a context paired with the toxin LiCl: influence of sex and the estrous cycle","volume":"173","author":"Cloutier","year":"2018","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.physbeh.2021.113559_bib0007","doi-asserted-by":"crossref","first-page":"1557","DOI":"10.1097\/00001756-199905140-00030","article-title":"Rotation-induced conditioned rejection in the taste reactivity test","volume":"10","author":"Cordick","year":"1996","journal-title":"Neuroreport"},{"key":"10.1016\/j.physbeh.2021.113559_bib0008","doi-asserted-by":"crossref","DOI":"10.1016\/j.cpnec.2021.100032","article-title":"Love and fear in the times of sickness","author":"Dantzer","year":"2021","journal-title":"Comprehen. Psychoneuroendocrinol."},{"key":"10.1016\/j.physbeh.2021.113559_bib0009","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1037\/0735-7044.110.1.202","article-title":"Area postrema mediates the formation of rapid, conditioned palatability shifts in lithium treated rats","volume":"110","author":"Eckel","year":"1996","journal-title":"Behav. Neurosci."},{"key":"10.1016\/j.physbeh.2021.113559_bib0010","first-page":"47","article-title":"Behaviour in the novel environment predicts responsiveness to d-amphetamine in the rat: a multivariate approach","volume":"4","author":"Exner","year":"1993","journal-title":"Behavioral Pharmacology"},{"key":"10.1016\/j.physbeh.2021.113559_bib0011","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1111\/j.1749-6632.1985.tb27060.x","article-title":"A general theory of aversion learning","volume":"443","author":"Garcia","year":"1985","journal-title":"Ann. N. Y. Acad. Sci."},{"issue":"4","key":"10.1016\/j.physbeh.2021.113559_bib0012","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1188\/15.CJON.438-443","article-title":"Delayed chemotherapy-induced nausea and vomiting in the hematology population: a review of the literature","volume":"19","author":"Gonella","year":"2015","journal-title":"Clin J Oncol Nurs"},{"key":"10.1016\/j.physbeh.2021.113559_bib0013","series-title":"Progress in Psychobiology and Physiological Psychology","first-page":"1","article-title":"Taste reactivity as a measure of the neural control of palatability","author":"Grill","year":"1985"},{"key":"10.1016\/j.physbeh.2021.113559_bib0014","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/0006-8993(78)90568-1","article-title":"The taste reactivity test: I. Mimetic responses to gustatory stimuli in neurologically normal rats","volume":"143","author":"Grill","year":"1978","journal-title":"Brain Res."},{"key":"10.1016\/j.physbeh.2021.113559_bib0015","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.pnpbp.2017.03.005","article-title":"Neurobehavioural effects of lithium in the rat: investigation of the effect\/concentration relationships and the contribution of the poisoning pattern","volume":"76","author":"Hanak","year":"2017","journal-title":"Progr. Neuropsychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.physbeh.2021.113559_bib0016","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1007\/BF01937771","article-title":"Lithium effects upon components of activity in rats","volume":"32","author":"Johnson","year":"1976","journal-title":"Experientia"},{"key":"10.1016\/j.physbeh.2021.113559_bib0017","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/j.ejphar.2013.09.071","article-title":"Anticipatory nausea and vomiting due to chemotherapy","volume":"722","author":"Kamen","year":"2014","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.physbeh.2021.113559_bib0018","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/0028-3908(86)90061-4","article-title":"Conditioned taste aversions and motor activity changes in lithium treated rats: mediating role of the area postrema","volume":"25","author":"Ladowsky","year":"1986","journal-title":"Neuropharmacology"},{"issue":"4\u20135","key":"10.1016\/j.physbeh.2021.113559_bib0019","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1016\/j.physbeh.2006.04.014","article-title":"Exposure to a lithium-paired context elicits gaping in rats: a model of anticipatory nausea","volume":"88","author":"Limebeer","year":"2006","journal-title":"Physiol. Behav."},{"issue":"1","key":"10.1016\/j.physbeh.2021.113559_bib0020","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.bbr.2007.08.024","article-title":"Exposure to a context previously associated with nausea elicits conditioned gaping in rats: a model of anticipatory nausea","volume":"187","author":"Limebeer","year":"2008","journal-title":"Behav. Brain Res."},{"issue":"4","key":"10.1016\/j.physbeh.2021.113559_bib0021","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1007\/s00213-008-1421-3","article-title":"Effect of 5-HT3 antagonists and a 5-HT(1A) agonist on fluoxetine-induced conditioned gaping reactions in rats","volume":"203","author":"Limebeer","year":"2009","journal-title":"Psychopharmacology (Berl)"},{"issue":"2","key":"10.1016\/j.physbeh.2021.113559_bib0022","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1007\/s00213-002-1309-6","article-title":"The 5-HT1A agonist 8-OH-DPAT dose-dependently interferes with the establishment and the expression of lithium-induced conditioned rejection reactions in rats","volume":"166","author":"Limebeer","year":"2003","journal-title":"Psychopharmacology (Berl)"},{"issue":"4","key":"10.1016\/j.physbeh.2021.113559_bib0023","first-page":"371","article-title":"The antiemetic drug ondansetron interferes with lithium-induced conditioned rejection reactions, but not lithium-induced taste avoidance in rats","volume":"26","author":"Limebeer","year":"2000","journal-title":"J.f Exper. Psychol."},{"key":"10.1016\/j.physbeh.2021.113559_bib0024","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1016\/0031-9384(92)90368-C","article-title":"Behavioral conditioned responses to contextual and odor stimuli paired with LiCl administration","volume":"52","author":"Meachum","year":"1992","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.physbeh.2021.113559_bib0025","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/S0091-3057(00)00303-8","article-title":"Perinatal exposure to lead attenuates the conditioned reinforcing properties of cocaine in male rats","volume":"67","author":"Miller","year":"2000","journal-title":"Pharmacol. Biochem. Behav.,"},{"issue":"1","key":"10.1016\/j.physbeh.2021.113559_bib0026","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.ejon.2005.01.010","article-title":"Managing nausea and vomiting after cancer treatments: patients still suffer unnecessarily","volume":"9","author":"Molassiotis","year":"2005","journal-title":"Eu. J. Oncol. Nurs."},{"issue":"6","key":"10.1016\/j.physbeh.2021.113559_bib0027","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1016\/j.jpainsymman.2015.12.317","article-title":"Anticipatory nausea, risk factors, and its impact on chemotherapy-induced nausea and vomiting: results from the Pan European emesis registry study","volume":"51","author":"Molassiotis","year":"2016","journal-title":"J Pain Symptom Manage"},{"key":"10.1016\/j.physbeh.2021.113559_bib0028","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/0031-9384(73)90089-9","article-title":"Learned taste aversions in rats as a function of dosage, concentration, and route of administration of LiCl","volume":"10","author":"Nachman","year":"1973","journal-title":"Physiol. Behav."},{"issue":"6","key":"10.1016\/j.physbeh.2021.113559_bib0029","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1016\/j.neubiorev.2007.04.002","article-title":"The Behavioral actions of lithium in rodent models leads to develop novel therapeutics","volume":"31","author":"O'Donnell","year":"2007","journal-title":"Neurosci. Biobehav. Rev."},{"issue":"1","key":"10.1016\/j.physbeh.2021.113559_bib0030","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/0149-7634(94)00024-U","article-title":"Toxin-induced conditioned changes in taste reactivity and the role of the chemosensitive area postrema","volume":"19","author":"Ossenkopp","year":"1995","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.physbeh.2021.113559_bib0031","series-title":"In: Ossenkopp, K-P., Kavaliers, M., Sanberg, PR. (eds.) Measuring Movement and Locomotion: From Invertebrates to Humans","first-page":"33","article-title":"Measuring spontaneous locomotor activity in small mammals","author":"Ossenkopp","year":"1996"},{"key":"10.1016\/j.physbeh.2021.113559_bib0032","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1016\/0091-3057(87)90368-6","article-title":"Automated multivariate measurement of spontaneous motor activity in mice: time course and reliabilities of the behavioral measures","volume":"27","author":"Ossenkopp","year":"1987","journal-title":"Pharmacol. Biochem. Behav.,"},{"key":"10.1016\/j.physbeh.2021.113559_bib0033","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1037\/0735-7044.117.1.105","article-title":"Vestibular lesions selectively abolish body rotation-induced, but not lithium-induced, conditioned taste aversions (oral rejection responses) in rats","volume":"117","author":"Ossenkopp","year":"2003","journal-title":"Behav. Neurosci."},{"key":"10.1016\/j.physbeh.2021.113559_bib0034","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/0023-9690(82)90011-X","article-title":"Nonconsummatory and consummatory behavioral CRs elicited by lithium- and amphetamine-paired flavors","volume":"13","author":"Parker","year":"1982","journal-title":"Learn Motiv"},{"key":"10.1016\/j.physbeh.2021.113559_bib0035","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1037\/0735-7044.106.2.294","article-title":"Place conditioning in a three-or four-choice apparatus: role of stimulus novelty in drug-induced place conditioning","volume":"106","author":"Parker","year":"1992","journal-title":"Behav. Neurosci."},{"key":"10.1016\/j.physbeh.2021.113559_bib0036","first-page":"3","article-title":"Emetic drugs produce conditioned rejection reactions in the taste reactivity test","volume":"12","author":"Parker","year":"1998","journal-title":"J. Psychophysiol."},{"key":"10.1016\/j.physbeh.2021.113559_bib0037","doi-asserted-by":"crossref","first-page":"307","DOI":"10.3758\/BF03199972","article-title":"Behavioral CRs elicited by a lithium- or an amphetamine-paired contextual test chamber","volume":"12","author":"Parker","year":"1984","journal-title":"Animal Learn. Behav."},{"issue":"1\u20132","key":"10.1016\/j.physbeh.2021.113559_bib0038","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.autneu.2006.07.022","article-title":"Conditioned gaping in rats: a selective measure of nausea","volume":"129","author":"Parker","year":"2006","journal-title":"Auton. Neurosci."},{"issue":"3","key":"10.1016\/j.physbeh.2021.113559_bib0039","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1037\/a0012531","article-title":"Conditioned nausea in rats: assessment by conditioned disgust reactions, rather than conditioned taste avoidance","volume":"62","author":"Parker","year":"2008","journal-title":"Canadian J. Exper. Psychol."},{"issue":"2","key":"10.1016\/j.physbeh.2021.113559_bib0040","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/j.physbeh.2011.01.006","article-title":"Repeated social defeat increases reactive emotional copying behavior and alters functional responses in serotonergic neurons in the rat dorsal raphe nucleus","volume":"104","author":"Paul","year":"2011","journal-title":"Physiol. Behav."},{"issue":"4","key":"10.1016\/j.physbeh.2021.113559_bib0041","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1016\/j.pbb.2008.09.005","article-title":"Potential of the rat model of conditioned gaping to detect nausea produced by rolipram, a phosphodiesterase-4 (PDE4) inhibitor","volume":"91","author":"Rock","year":"2009","journal-title":"Pharmacol. Biochem. Behav."},{"issue":"1","key":"10.1016\/j.physbeh.2021.113559_bib0042","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1089\/can.2016.0006","article-title":"Cannabinoid regulation of acute and anticipatory nausea","volume":"1","author":"Rock","year":"2016","journal-title":"Cannabis Cannabinoid Res."},{"issue":"5","key":"10.1016\/j.physbeh.2021.113559_bib0043","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1016\/S0031-9384(00)00376-0","article-title":"Lithium-induced context aversion in rats as a model of anticipatory nausea in humans","volume":"71","author":"Rodriguez","year":"2000","journal-title":"Physiol. Behavior"},{"issue":"10","key":"10.1016\/j.physbeh.2021.113559_bib0044","first-page":"1533","article-title":"Anticipatory nausea and vomiting","volume":"19","author":"Roscoe","year":"2011","journal-title":"Support Care Cancer"},{"issue":"1","key":"10.1016\/j.physbeh.2021.113559_bib0045","first-page":"87","article-title":"Automated measurement of multivariate locomotor behavior in rodents","volume":"7","author":"Sanberg","year":"1985","journal-title":"Neurobehav. Toxicol. Teratol."},{"issue":"5","key":"10.1016\/j.physbeh.2021.113559_bib0046","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1080\/10253890.2018.1438405","article-title":"Exploratory rearing: a context- and stress-sensitive behavior recorded in the open-field test","volume":"21","author":"Sturman","year":"2018","journal-title":"Stress"},{"issue":"1","key":"10.1016\/j.physbeh.2021.113559_bib0047","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.ejphar.2005.04.007","article-title":"Dose response effects of lithium chloride on conditioned place aversions and locomotor activity in rats","volume":"515","author":"Tenk","year":"2005","journal-title":"Eur. J. Pharmacol."},{"issue":"11","key":"10.1016\/j.physbeh.2021.113559_bib0048","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1016\/j.lfs.2006.03.008","article-title":"The effects of acute corticosterone on lithium chloride-induced conditioned place aversion and locomotor activity in rats","volume":"79","author":"Tenk","year":"2006","journal-title":"Life Sci."},{"key":"10.1016\/j.physbeh.2021.113559_bib0049","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.brainres.2006.03.102","article-title":"Behavioural effects of short-term administration of lithium and valproic acid in rats","volume":"1093","author":"Tomaseiwics","year":"2006","journal-title":"Brain Res."},{"issue":"2","key":"10.1016\/j.physbeh.2021.113559_bib0050","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/j.pbb.2009.05.011","article-title":"Antidepressant-like effects of paroxetine are produced by lower doses than those which produce nausea","volume":"93","author":"Tuerke","year":"2009","journal-title":"Pharmacology, Biochem. Behav.,"},{"issue":"6","key":"10.1016\/j.physbeh.2021.113559_bib0051","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1037\/emo0000195","article-title":"Insular atrophy and diminished disgust reactivity","volume":"16","author":"Verstaen","year":"2016","journal-title":"Emotion"},{"key":"10.1016\/j.physbeh.2021.113559_bib0052","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/0091-3057(85)90127-3","article-title":"The conditioned place preference is affected by two independent reinforcement processes","volume":"23","author":"White","year":"1985","journal-title":"Pharmacol. Biochem. Behav."}],"container-title":["Physiology &amp; Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0031938421002481?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0031938421002481?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T18:21:23Z","timestamp":1758478883000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0031938421002481"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10]]},"references-count":52,"alternative-id":["S0031938421002481"],"URL":"https:\/\/doi.org\/10.1016\/j.physbeh.2021.113559","relation":{},"ISSN":["0031-9384"],"issn-type":[{"type":"print","value":"0031-9384"}],"subject":[],"published":{"date-parts":[[2021,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Toxin-induced aversive context conditioning: Assessing active aversive behaviors conditioned to the context of an automated activity monitor","name":"articletitle","label":"Article Title"},{"value":"Physiology & Behavior","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.physbeh.2021.113559","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"113559"}}