{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T02:55:52Z","timestamp":1791082552535,"version":"4.1.0"},"reference-count":62,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100008321","name":"Pennsylvania State University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008321","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["R01 AG039409"],"award-info":[{"award-number":["R01 AG039409"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["R01 AG042595"],"award-info":[{"award-number":["R01 AG042595"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["T32 AG049676"],"award-info":[{"award-number":["T32 AG049676"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Physiology &amp; Behavior"],"published-print":{"date-parts":[[2022,2]]},"DOI":"10.1016\/j.physbeh.2021.113656","type":"journal-article","created":{"date-parts":[[2021,11,25]],"date-time":"2021-11-25T02:03:10Z","timestamp":1637805790000},"page":"113656","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"special_numbering":"C","title":["Depressive symptoms and other negative psychological states relate to ex vivo inflammatory responses differently for men and women: Cross-sectional and longitudinal evidence"],"prefix":"10.1016","volume":"244","author":[{"given":"Erik L.","family":"Knight","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marzieh","family":"Majd","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer E.","family":"Graham-Engeland","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua M.","family":"Smyth","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin J.","family":"Sliwinski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher G.","family":"Engeland","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.physbeh.2021.113656_bib0001","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/S1047-2797(97)00014-8","article-title":"Major depression and all-cause mortality among white adults in the United States","volume":"7","author":"Zheng","year":"1997","journal-title":"Ann. Epidemiol."},{"key":"10.1016\/j.physbeh.2021.113656_bib0002","doi-asserted-by":"crossref","first-page":"600","DOI":"10.3109\/10253890.2013.823943","article-title":"Perceived stress and mortality in a Taiwanese older adult population","volume":"16","author":"Vasunilashorn","year":"2013","journal-title":"Stress"},{"key":"10.1016\/j.physbeh.2021.113656_bib0003","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1093\/aje\/kwn157","article-title":"Perceived stress and cause-specific mortality among men and women: results from a prospective cohort study","volume":"168","author":"Nielsen","year":"2008","journal-title":"Am. J. Epidemiol."},{"key":"10.1016\/j.physbeh.2021.113656_bib0004","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1146\/annurev-psych-062520-122331","article-title":"Stress and health: a review of psychobiological processes","volume":"72","author":"O'Connor","year":"2021","journal-title":"Annu. Rev. Psychol."},{"key":"10.1016\/j.physbeh.2021.113656_bib0005","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/j.bbi.2006.07.005","article-title":"Depressive symptoms and production of proinflammatory cytokines by peripheral blood mononuclear cells stimulated in vitro","volume":"21","author":"Cyranowski","year":"2007","journal-title":"Brain. Behav. Immun."},{"key":"10.1016\/j.physbeh.2021.113656_bib0006","doi-asserted-by":"crossref","first-page":"1553","DOI":"10.1016\/j.psyneuen.2011.04.009","article-title":"LPS-stimulated tumor necrosis factor-alpha and interleukin-6 mRNA and cytokine responses following acute psychological stress","volume":"36","author":"Huang","year":"2011","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.physbeh.2021.113656_bib0007","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1146\/annurev.psych.53.100901.135217","article-title":"Emotions, morbidity, and mortality: new perspectives from psychoneuroimmunology","volume":"53","author":"Kiecolt-Glaser","year":"2002","journal-title":"Annu. Rev. Psychol."},{"key":"10.1016\/j.physbeh.2021.113656_bib0008","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1038\/nri1571","article-title":"Stress-induced immune dysfunction: implications for health","volume":"5","author":"Glaser","year":"2005","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.physbeh.2021.113656_bib0009","doi-asserted-by":"crossref","first-page":"e825","DOI":"10.1038\/tp.2016.92","article-title":"Cytokine production capacity in depression and anxiety","volume":"6","author":"Vogelzangs","year":"2016","journal-title":"Transl. Psychiatry."},{"key":"10.1016\/j.physbeh.2021.113656_bib0010","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1080\/15622975.2019.1671608","article-title":"Circulating versus lipopolysaccharide-induced inflammatory markers as correlates of subthreshold depressive symptoms in older adults","volume":"21","author":"Lee","year":"2020","journal-title":"World J. Biol. Psychiatry."},{"key":"10.1016\/j.physbeh.2021.113656_bib0011","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1146\/annurev.psych.60.110707.163551","article-title":"Health psychology: developing biologically plausible models linking the social world and physical health","volume":"60","author":"Miller","year":"2009","journal-title":"Annu. Rev. Psychol."},{"key":"10.1016\/j.physbeh.2021.113656_bib0012","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1385\/IR:34:3:177","article-title":"Sexual dimorphism in innate immune responses to infectious organisms","volume":"34","author":"Marriott","year":"2006","journal-title":"Immunol. Res."},{"key":"10.1016\/j.physbeh.2021.113656_bib0013","doi-asserted-by":"crossref","unstructured":"M. Majd, J.E. Graham-Engeland, J.M. Smyth, M.J. Sliwinski, R.B. Lipton, M.J. Katz, C.G. Engeland, Distinct inflammatory response patterns are evident among men and women with higher depressive symptoms, Physiol. Behav. (2018). 10.1016\/j.physbeh.2017.11.009.","DOI":"10.1016\/j.physbeh.2017.11.009"},{"key":"10.1016\/j.physbeh.2021.113656_bib0014","article-title":"Gender differences in the link between depressive symptoms and ex vivo inflammatory responses are associated with markers of endotoxemia","volume":"2","author":"Knight","year":"2020","journal-title":"Brain, Behav. Immun. - Heal."},{"key":"10.1016\/j.physbeh.2021.113656_bib0015","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.psyneuen.2018.05.035","article-title":"Gender differences in longitudinal relationships between depression and anxiety symptoms and inflammation in the health and retirement study","volume":"95","author":"Niles","year":"2018","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.physbeh.2021.113656_bib0016","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.1001\/archinte.164.9.1010","article-title":"Depression and C-reactive protein in US adults","volume":"164","author":"Ford","year":"2004","journal-title":"Arch. Intern. Med."},{"key":"10.1016\/j.physbeh.2021.113656_bib0017","doi-asserted-by":"crossref","DOI":"10.1016\/j.yfrne.2019.100800","article-title":"Inflammation and the dimensions of depression: a review","volume":"56","author":"Majd","year":"2020","journal-title":"Front. Neuroendocrinol."},{"key":"10.1016\/j.physbeh.2021.113656_bib0018","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/j.bbi.2006.07.006","article-title":"Stimulated production of interleukin-8 covaries with psychosocial risk factors for inflammatory disease among middle-aged community volunteers","volume":"21","author":"Marsland","year":"2007","journal-title":"Brain. Behav. Immun."},{"key":"10.1016\/j.physbeh.2021.113656_bib0019","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/j.biopsycho.2012.12.003","article-title":"Effort\u2013reward-imbalance in healthy teachers is associated with higher LPS-stimulated production and lower glucocorticoid sensitivity of interleukin-6 in vitro","volume":"92","author":"Bellingrath","year":"2013","journal-title":"Biol. Psychol."},{"key":"10.1016\/j.physbeh.2021.113656_bib0020","doi-asserted-by":"crossref","first-page":"1290","DOI":"10.1111\/j.1469-8986.2012.01409.x","article-title":"Effects of high and low stress on proinflammatory and antiinflammatory cytokines","volume":"49","author":"Koh","year":"2012","journal-title":"Psychophysiology"},{"key":"10.1016\/j.physbeh.2021.113656_bib0021","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1177\/0193945914545658","article-title":"Effect of perceived stress on cytokine production in healthy college students","volume":"37","author":"Sribanditmongkol","year":"2015","journal-title":"West. J. Nurs. Res."},{"key":"10.1016\/j.physbeh.2021.113656_bib0022","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1097\/PSY.0b013e318190d7de","article-title":"Chronic interpersonal stress predicts activation of pro- and anti-inflammatory signaling pathways 6 months later","volume":"71","author":"Miller","year":"2009","journal-title":"Psychosom. Med."},{"key":"10.1016\/j.physbeh.2021.113656_bib0023","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1007\/s10522-019-09829-y","article-title":"High perceived stress in women is linked to oxidation, inflammation and immunosenescence","volume":"20","author":"Mart\u00ednez de Toda","year":"2019","journal-title":"Biogerontology"},{"key":"10.1016\/j.physbeh.2021.113656_bib0024","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1016\/j.bbi.2021.01.015","article-title":"Perceived stress is linked to heightened biomarkers of inflammation via diurnal cortisol in a national sample of adults","volume":"93","author":"Knight","year":"2021","journal-title":"Brain. Behav. Immun."},{"key":"10.1016\/j.physbeh.2021.113656_bib0025","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1080\/10253890500141905","article-title":"Perceived stress and physiological dysregulation in older adults","volume":"8","author":"Goldman","year":"2005","journal-title":"Stress"},{"key":"10.1016\/j.physbeh.2021.113656_bib0026","doi-asserted-by":"crossref","unstructured":"P.D. Trapnell, J.D. Campbell, Private self-consciousness and the five-factor model of personality: distinguishing rumination from reflection, J. Pers. Soc. Psychol. (1999). 10.1037\/0022-3514.76.2.284.","DOI":"10.1037\/\/0022-3514.76.2.284"},{"key":"10.1016\/j.physbeh.2021.113656_bib0027","doi-asserted-by":"crossref","first-page":"2149","DOI":"10.1007\/s10964-020-01216-y","article-title":"Reward sensitivity, cognitive response style, and inflammatory response to an acute stressor in adolescents","volume":"49","author":"Moriarity","year":"2020","journal-title":"J. Youth Adolesc."},{"key":"10.1016\/j.physbeh.2021.113656_bib0028","doi-asserted-by":"crossref","unstructured":"D.P. Moriarity, T. Ng, M.K. Titone, I.K.Y. Chat, R. Nusslock, G.E. Miller, L.B. Alloy, Reward responsiveness and ruminative styles interact to predict inflammation and mood symptomatology, Behav. Ther. (2020). 10.1016\/j.beth.2019.11.007.","DOI":"10.1016\/j.beth.2019.11.007"},{"key":"10.1016\/j.physbeh.2021.113656_bib0029","doi-asserted-by":"crossref","first-page":"1606","DOI":"10.1037\/hea0000019","article-title":"Differential effects of poststressor rumination and distraction on cortisol and C-reactive protein","volume":"33","author":"Zoccola","year":"2014","journal-title":"Heal. Psychol."},{"key":"10.1016\/j.physbeh.2021.113656_bib0030","doi-asserted-by":"crossref","unstructured":"D.R. Jones, J.E. Graham-Engeland, Positive affect and peripheral inflammatory markers among adults: a narrative review, Psychoneuroendocrinology. (2021). 10.1016\/j.psyneuen.2020.104892.","DOI":"10.1016\/j.psyneuen.2020.104892"},{"key":"10.1016\/j.physbeh.2021.113656_bib0031","doi-asserted-by":"crossref","unstructured":"J.E. Graham-Engeland, N.L. Sin, J.M. Smyth, D.R. Jones, E.L. Knight, M.J. Sliwinski, D.M. Almeida, M.J. Katz, R.B. Lipton, C.G. Engeland, Negative and positive affect as predictors of inflammation: timing matters, Brain. Behav. Immun. (2018). 10.1016\/j.bbi.2018.09.011.","DOI":"10.1016\/j.bbi.2018.09.011"},{"key":"10.1016\/j.physbeh.2021.113656_bib0032","doi-asserted-by":"crossref","unstructured":"A. Steptoe, K. O'Donnell, E. Badrick, M. Kumari, M. Marmot, Neuroendocrine and inflammatory factors associated with positive affect in healthy men and women: the Whitehall II study, Am. J. Epidemiol. (2008). 10.1093\/aje\/kwm252.","DOI":"10.1093\/aje\/kwm252"},{"key":"10.1016\/j.physbeh.2021.113656_bib0033","doi-asserted-by":"crossref","unstructured":"A.A. Prather, A.L. Marsland, M.F. Muldoon, S.B. Manuck, Positive affective style covaries with stimulated IL-6 and IL-10 production in a middle-aged community sample, Brain. Behav. Immun. (2007). 10.1016\/j.bbi.2007.04.009.","DOI":"10.1016\/j.bbi.2007.04.009"},{"key":"10.1016\/j.physbeh.2021.113656_bib0034","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1186\/s12888-015-0497-7","article-title":"The effects of stress on cognitive aging, physiology, and emotion (ESCAPE) project","volume":"15","author":"Scott","year":"2015","journal-title":"BMC Psychiatry"},{"key":"10.1016\/j.physbeh.2021.113656_bib0035","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.1097\/01.mlr.0000258615.42478.55","article-title":"The patient-reported outcomes measurement information system (PROMIS)","volume":"45","author":"Cella","year":"2007","journal-title":"Med. Care."},{"key":"10.1016\/j.physbeh.2021.113656_bib0036","doi-asserted-by":"crossref","first-page":"385","DOI":"10.2307\/2136404","article-title":"A global measure of perceived stress","volume":"24","author":"Cohen","year":"1983","journal-title":"J. Health Soc. Behav."},{"key":"10.1016\/j.physbeh.2021.113656_bib0037","doi-asserted-by":"crossref","unstructured":"D. Watson, L.A. Clark, A. Tellegen, Development and validation of brief measures of positive and negative affect: the PANAS scales., J. Pers. Soc. Psychol. (1988). 10.1037\/\/0022-3514.54.6.1063.","DOI":"10.1037\/\/0022-3514.54.6.1063"},{"key":"10.1016\/j.physbeh.2021.113656_bib0038","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1002\/dev.21173","article-title":"Within-person coupling of changes in cortisol, testosterone, and DHEA across the day in adolescents","volume":"57","author":"Marceau","year":"2015","journal-title":"Dev. Psychobiol."},{"key":"10.1016\/j.physbeh.2021.113656_bib0039","doi-asserted-by":"crossref","first-page":"1533","DOI":"10.1152\/japplphysiol.00335.2020","article-title":"Let's talk about sex in the context of COVID-19","volume":"128","author":"Gargaglioni","year":"2020","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.physbeh.2021.113656_bib0040","unstructured":"J.K. Kiecolt-Glaser, R. Glaser, S. Gravenstein, W.B. Malarkey, J. Sheridan, R. Glaser, Chronic stress and age-related increases in the proinflammatory cytokine IL-6, Proc. Natl. Acad. Sci. U. S. A. (1996). 10.1073\/pnas.93.7.3043."},{"key":"10.1016\/j.physbeh.2021.113656_bib0041","doi-asserted-by":"crossref","first-page":"1194","DOI":"10.1016\/S0140-6736(95)92899-5","article-title":"Slowing of wound healing by psychological stress","volume":"346","author":"Kiecolt-Glaser","year":"1995","journal-title":"Lancet"},{"key":"10.1016\/j.physbeh.2021.113656_bib0042","doi-asserted-by":"crossref","unstructured":"F. Mauvais-Jarvis, N. Bairey Merz, P.J. Barnes, R.D. Brinton, J.J. Carrero, D.L. DeMeo, G.J. De Vries, C.N. Epperson, R. Govindan, S.L. Klein, A. Lonardo, P.M. Maki, L.D. McCullough, V. Regitz-Zagrosek, J.G. Regensteiner, J.B. Rubin, K. Sandberg, A. Suzuki, Sex and gender: modifiers of health, disease, and medicine, Lancet. (2020). 10.1016\/S0140-6736(20)31561-0.","DOI":"10.1016\/S0140-6736(20)31561-0"},{"key":"10.1016\/j.physbeh.2021.113656_bib0043","doi-asserted-by":"crossref","unstructured":"C.P. Fagundes, K.W. Murdock, A. LeRoy, F. Baameur, J.F. Thayer, C. Heijnen, Spousal bereavement is associated with more pronounced ex vivo cytokine production and lower heart rate variability: mechanisms underlying cardiovascular risk?, Psychoneuroendocrinology. (2018). 10.1016\/j.psyneuen.2018.04.010.","DOI":"10.1016\/j.psyneuen.2018.04.010"},{"key":"10.1016\/j.physbeh.2021.113656_bib0044","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1016\/j.psyneuen.2004.01.002","article-title":"Enhanced expression of cytokines and chemokines by blood monocytes to in vitro lipopolysaccharide stimulation are associated with hostility and severity of depressive symptoms in healthy women","volume":"29","author":"Suarez","year":"2004","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.physbeh.2021.113656_bib0045","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1016\/S0889-1591(02)00019-3","article-title":"The relation of aggression, hostility, and anger to lipopolysaccharide-stimulated tumor necrosis factor (TNF)-\u03b1 by blood monocytes from normal men","volume":"16","author":"Suarez","year":"2002","journal-title":"Brain. Behav. Immun."},{"key":"10.1016\/j.physbeh.2021.113656_bib0046","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/j.bbi.2016.07.156","article-title":"Social role conflict predicts stimulated cytokine production among men, not women","volume":"58","author":"Schreier","year":"2016","journal-title":"Brain. Behav. Immun."},{"key":"10.1016\/j.physbeh.2021.113656_bib0047","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1016\/S0889-1591(02)00021-1","article-title":"Stress and the inflammatory response: a review of neurogenic inflammation","volume":"16","author":"Black","year":"2002","journal-title":"Brain. Behav. Immun."},{"key":"10.1016\/j.physbeh.2021.113656_bib0048","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.bbi.2017.01.011","article-title":"The effects of acute psychological stress on circulating and stimulated inflammatory markers: a systematic review and meta-analysis","volume":"64","author":"Marsland","year":"2017","journal-title":"Brain. Behav. Immun."},{"key":"10.1016\/j.physbeh.2021.113656_bib0049","doi-asserted-by":"crossref","DOI":"10.1016\/j.psyneuen.2020.104863","article-title":"Ex vivo LPS-stimulated cytokine production is associated with cortisol curves in response to acute psychosocial stress","volume":"121","author":"Davis","year":"2020","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.physbeh.2021.113656_bib0050","doi-asserted-by":"crossref","first-page":"A479","DOI":"10.1016\/j.autrev.2011.11.022","article-title":"The influence of sex and gender on the immune response","volume":"11","author":"Oertelt-Prigione","year":"2012","journal-title":"Autoimmun. Rev."},{"key":"10.1016\/j.physbeh.2021.113656_bib0051","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1038\/nri2815","article-title":"The X chromosome in immune functions: when a chromosome makes the difference","volume":"10","author":"Libert","year":"2010","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.physbeh.2021.113656_bib0052","doi-asserted-by":"crossref","unstructured":"J.A.P. Da Silva, Sex hormones and glucocorticoids: interactions with the immune system, in: Ann. N. Y. Acad. Sci., 1999. 10.1111\/j.1749-6632.1999.tb07628.x.","DOI":"10.1111\/j.1749-6632.1999.tb07628.x"},{"key":"10.1016\/j.physbeh.2021.113656_bib0053","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1186\/s13293-018-0187-5","article-title":"Sexual dimorphism in bacterial infections","volume":"9","author":"V\u00e1zquez-Mart\u00ednez","year":"2018","journal-title":"Biol. Sex Differ."},{"key":"10.1016\/j.physbeh.2021.113656_bib0054","article-title":"A plausible explanation for male dominance in typhoid ileal perforation","volume":"213","author":"Khan","year":"2012","journal-title":"Clin. Exp. Gastroenterol."},{"key":"10.1016\/j.physbeh.2021.113656_bib0055","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.jri.2006.01.004","article-title":"Sexual dimorphism in expression of receptors for bacterial lipopolysaccharides in murine macrophages: a possible mechanism for gender-based differences in endotoxic shock susceptibility","volume":"71","author":"Marriott","year":"2006","journal-title":"J. Reprod. Immunol."},{"key":"10.1016\/j.physbeh.2021.113656_bib0056","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1038\/s41386-019-0316-9","article-title":"Transcriptomic predictors of inflammation-induced depressed mood","volume":"44","author":"Cho","year":"2019","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.physbeh.2021.113656_bib0057","doi-asserted-by":"crossref","unstructured":"E.C. Suarez, Sex differences in the relation of depressive symptoms, hostility, and anger expression to indices of glucose metabolism in nondiabetic adults, Heal. Psychol. (2006). 10.1037\/0278-6133.25.4.484.","DOI":"10.1037\/0278-6133.25.4.484"},{"key":"10.1016\/j.physbeh.2021.113656_bib0058","doi-asserted-by":"crossref","unstructured":"A.A. Prather, J.E. Carroll, J.M. Fury, K.K. McDade, D. Ross, A.L. Marsland, Gender differences in stimulated cytokine production following acute psychological stress, Brain. Behav. Immun. (2009). 10.1016\/j.bbi.2008.11.004.","DOI":"10.1016\/j.bbi.2008.11.004"},{"key":"10.1016\/j.physbeh.2021.113656_bib0059","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1097\/00006842-200111000-00016","article-title":"Sex differences in glucocorticoid sensitivity of proinflammatory cytokine production after psychosocial stress","volume":"63","author":"Rohleder","year":"2001","journal-title":"Psychosom. Med."},{"key":"10.1016\/j.physbeh.2021.113656_bib0060","unstructured":"W. Revelle, psych: procedures for Personality and Psychological Research, (2020). https:\/\/cran.r-project.org\/package=psych."},{"key":"10.1016\/j.physbeh.2021.113656_bib0061","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1016\/j.bbi.2009.02.019","article-title":"Sex and gender in psychoneuroimmunology research: past, present and future","volume":"23","author":"Darnall","year":"2009","journal-title":"Brain. Behav. Immun."},{"key":"10.1016\/j.physbeh.2021.113656_bib0062","doi-asserted-by":"crossref","unstructured":"P.E. Shrout, J.L. Fleiss, Intraclass correlations: uses in assessing rater reliability, Psychol. Bull. (1979). 10.1037\/0033-2909.86.2.420.","DOI":"10.1037\/\/0033-2909.86.2.420"}],"container-title":["Physiology &amp; Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0031938421003437?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0031938421003437?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T18:21:20Z","timestamp":1758478880000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0031938421003437"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2]]},"references-count":62,"alternative-id":["S0031938421003437"],"URL":"https:\/\/doi.org\/10.1016\/j.physbeh.2021.113656","relation":{},"ISSN":["0031-9384"],"issn-type":[{"value":"0031-9384","type":"print"}],"subject":[],"published":{"date-parts":[[2022,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Depressive symptoms and other negative psychological states relate to ex vivo inflammatory responses differently for men and women: Cross-sectional and longitudinal evidence","name":"articletitle","label":"Article Title"},{"value":"Physiology & Behavior","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.physbeh.2021.113656","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"113656"}}