{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T11:04:14Z","timestamp":1780743854576,"version":"3.54.1"},"reference-count":35,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100002873","name":"Chulalongkorn University","doi-asserted-by":"publisher","award":["RCU_H_64_032_31"],"award-info":[{"award-number":["RCU_H_64_032_31"]}],"id":[{"id":"10.13039\/501100002873","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002873","name":"Chulalongkorn University","doi-asserted-by":"publisher","award":["GCUGR1125631090D"],"award-info":[{"award-number":["GCUGR1125631090D"]}],"id":[{"id":"10.13039\/501100002873","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Physiology &amp; Behavior"],"published-print":{"date-parts":[[2022,3]]},"DOI":"10.1016\/j.physbeh.2021.113687","type":"journal-article","created":{"date-parts":[[2021,12,20]],"date-time":"2021-12-20T03:31:42Z","timestamp":1639971102000},"page":"113687","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"special_numbering":"C","title":["Arcuate proopiomelanocortin is part of a novel neural connection for short-term low-degree of high ambient temperature effects on food intake."],"prefix":"10.1016","volume":"245","author":[{"given":"Pornsiri","family":"Suwannapaporn","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Narongsak","family":"Chaiyabutr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aree","family":"Wanasuntronwong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sumpun","family":"Thammacharoen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.physbeh.2021.113687_bib0001","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1248\/bpb.26.701","article-title":"Dynamic responses to acute heat stress between 34 \u00b0C and 38.5 \u00b0C, and characteristics of heat stress response in mice","volume":"26","author":"Harikai","year":"2003","journal-title":"Biol. Pharm. Bull."},{"key":"10.1016\/j.physbeh.2021.113687_bib0002","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.cmet.2006.08.003","article-title":"Neuronal activation in the hypothalamus and brainstem during feeding in rats","volume":"4","author":"Johnstone","year":"2006","journal-title":"Cell. Metab."},{"key":"10.1016\/j.physbeh.2021.113687_bib0003","doi-asserted-by":"crossref","first-page":"890","DOI":"10.2337\/diabetes.47.6.890","article-title":"Hypothalamic corticotropin-releasing hormone is a mediator of the anorexigenic effect of leptin","volume":"47","author":"Uehara","year":"1998","journal-title":"Diabetes"},{"key":"10.1016\/j.physbeh.2021.113687_bib0004","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.physbeh.2017.08.027","article-title":"A low degree of high ambient temperature decreased food intake and activated median preoptic and arcuate nuclei","volume":"181","author":"Suwanapaporn","year":"2017","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.physbeh.2021.113687_bib0005","doi-asserted-by":"crossref","first-page":"8034","DOI":"10.3390\/ijerph120708034","article-title":"Limitations to Thermoregulation and Acclimatization Challenge Human Adaptation to Global Warming","volume":"12","author":"Hanna","year":"2015","journal-title":"Int. J. Environ. Res. Public. Health."},{"key":"10.1016\/j.physbeh.2021.113687_bib0006","doi-asserted-by":"crossref","DOI":"10.1016\/j.jtherbio.2020.102783","article-title":"High ambient temperature directly decreases milk synthesis in the mammary gland in Saanen goats","volume":"94","author":"Saipin","year":"2020","journal-title":"J. Therm. Biol."},{"key":"10.1016\/j.physbeh.2021.113687_bib0007","doi-asserted-by":"crossref","first-page":"169","DOI":"10.56808\/2985-1130.3015","article-title":"An analysis of herd-based lactation curve reveals the seasonal effect from dairy cows fed under high ambient temperature","volume":"50","author":"Thammacharoen","year":"2020","journal-title":"Thai. J. Vet. Med."},{"key":"10.1016\/j.physbeh.2021.113687_bib0008","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1007\/s11250-020-02541-x","article-title":"Heat stress in dairy animals and current milk production trends, economics, and future perspectives: the global scenario","volume":"53","author":"Wankar","year":"2021","journal-title":"Trop. Anim. Health. Prod."},{"key":"10.1016\/j.physbeh.2021.113687_bib0009","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1007\/s13679-011-0002-7","article-title":"Ambient temperature and obesity","volume":"1","author":"Moellering","year":"2012","journal-title":"Curr. Ob. Rep."},{"key":"10.1016\/j.physbeh.2021.113687_bib0010","doi-asserted-by":"crossref","first-page":"2328","DOI":"10.1002\/oby.20866","article-title":"Ambient temperature and prevalence of obesity in the Spanish population: the Di@bet.es study","volume":"22","author":"Vald\u00e9s","year":"2014","journal-title":"Obesity (Silver Spring)"},{"key":"10.1016\/j.physbeh.2021.113687_bib0011","doi-asserted-by":"crossref","first-page":"1407","DOI":"10.1038\/ijo.2013.5","article-title":"Association of elevation, urbanization and ambient temperature with obesity prevalence in the United States","volume":"37","author":"Voss","year":"2013","journal-title":"Int. J. Obes."},{"key":"10.1016\/j.physbeh.2021.113687_bib0012","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1159\/000054705","article-title":"Hypothalamic targets for prolactin: assessment of c-Fos induction in tyrosine hydroxylase- and proopiomelanocortin-containing neurones in the rat arcuate nucleus following acute central prolactin administration","volume":"74","author":"Cave","year":"2001","journal-title":"Neuroendocrinology"},{"key":"10.1016\/j.physbeh.2021.113687_bib0013","series-title":"The Rat Brain in Stereotaxic Coordination","author":"Paxinos","year":"1998"},{"key":"10.1016\/j.physbeh.2021.113687_bib0014","doi-asserted-by":"crossref","first-page":"15","DOI":"10.3389\/fnbeh.2019.00015","article-title":"Task-dependent differences in operant behaviors of rats with acute exposure to high ambient temperature: a potential role of hippocampal dopamine reuptake transporters","volume":"13","author":"Chen","year":"2019","journal-title":"Front. Behav. Neurosci."},{"key":"10.1016\/j.physbeh.2021.113687_bib0015","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jtherbio.2015.04.004","article-title":"Distinct vasopressin content in the hypothalamic supraoptic and paraventricular nucleus of rats exposed to low and high ambient temperature","volume":"52","author":"Jasnic","year":"2015","journal-title":"J. Therm. Biol."},{"key":"10.1016\/j.physbeh.2021.113687_bib0016","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.neuroscience.2018.05.045","article-title":"Short-term heat exposure promotes hippocampal neurogenesis via activation of angiotensin II type 1 receptor in adult rats","volume":"385","author":"Koyama","year":"2018","journal-title":"Neuroscience"},{"key":"10.1016\/j.physbeh.2021.113687_bib0017","doi-asserted-by":"crossref","first-page":"8848","DOI":"10.1073\/pnas.0913358107","article-title":"A thermosensory pathway mediating heat-defense responses","volume":"107","author":"Nakamura","year":"2010","journal-title":"Proc. Natl. Acad. Sci. U S A."},{"key":"10.1016\/j.physbeh.2021.113687_bib0018","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.jtherbio.2019.02.004","article-title":"Corticosterone tissue-specific response in Sprague Dawley rats under acute heat stress","volume":"81","author":"Dou","year":"2019","journal-title":"J. Therm. Biol."},{"key":"10.1016\/j.physbeh.2021.113687_bib0019","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1007\/s12192-020-01178-x","article-title":"Heat-induced endoplasmic reticulum stress in soleus and gastrocnemius muscles and differential response to UPR pathway in rats","volume":"26","author":"Sharma","year":"2021","journal-title":"Cell. Stress. Chaperones."},{"key":"10.1016\/j.physbeh.2021.113687_bib0020","doi-asserted-by":"crossref","first-page":"2667","DOI":"10.1152\/japplphysiol.01173.2001","article-title":"Ambient temperature for experiments in rats: a new method for determining the zone of thermal neutrality","volume":"92","author":"Romanovsky","year":"2002","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.physbeh.2021.113687_bib0021","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1016\/0031-9384(90)90025-Y","article-title":"Thermal biology of the laboratory rat","volume":"47","author":"Gordon","year":"1990","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.physbeh.2021.113687_bib0022","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1016\/S0149-7634(02)00016-7","article-title":"The temporal organization of ingestive behaviour and its interaction with regulation of energy balance","volume":"26","author":"Strubbe","year":"2002","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.physbeh.2021.113687_bib0023","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1210\/en.2013-1604","article-title":"The suprachiasmatic nucleus changes the daily activity of the arcuate nucleus alpha-MSH neurons in male rats","volume":"155","author":"Guzman-Ruiz","year":"2014","journal-title":"Endocrinology"},{"key":"10.1016\/j.physbeh.2021.113687_bib0024","doi-asserted-by":"crossref","first-page":"e12952","DOI":"10.1111\/jne.12952","article-title":"The regulation of food intake by insulin in the central nervous system","volume":"33","author":"Mitchell","year":"2021","journal-title":"J. Neuroendocrinol."},{"key":"10.1016\/j.physbeh.2021.113687_bib0025","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1038\/35007534","article-title":"Central nervous system control of food intake","volume":"404","author":"Schwartz","year":"2000","journal-title":"Nature"},{"key":"10.1016\/j.physbeh.2021.113687_bib0026","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1098\/rstb.2006.1855","article-title":"Neuropeptide Y in normal eating and in genetic and dietary-induced obesity","volume":"361","author":"Beck","year":"2006","journal-title":"Phil. Trans. of the Royal. Soc. B."},{"key":"10.1016\/j.physbeh.2021.113687_bib0027","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.molmet.2019.11.014","article-title":"Fasting induces remodeling of the orexigenic projections from the arcuate nucleus to the hypothalamic paraventricular nucleus, in a growth hormone secretagogue receptor-dependent manner","volume":"32","author":"Cabral","year":"2020","journal-title":"Mol. Metab."},{"key":"10.1016\/j.physbeh.2021.113687_bib0028","doi-asserted-by":"crossref","first-page":"2659","DOI":"10.1002\/cne.24698","article-title":"Afferent neuropeptide Y projections to the ventral tegmental area in normal-weight male Wistar rats","volume":"527","author":"Gumbs","year":"2019","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.physbeh.2021.113687_bib0029","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1038\/1082","article-title":"Coexpression of Agrp and NPY in fasting-activated hypothalamic neurons","volume":"1","author":"Hahn","year":"1998","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.physbeh.2021.113687_bib0030","doi-asserted-by":"crossref","first-page":"6224","DOI":"10.1038\/s41598-019-42728-3","article-title":"Hypoglycemia-activated hypothalamic microglia impairs glucose counterregulatory responses","volume":"9","author":"Winkler","year":"2019","journal-title":"Sci. Rep"},{"key":"10.1016\/j.physbeh.2021.113687_bib0031","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1016\/j.cell.2015.01.033","article-title":"Sensory detection of food rapidly modulates arcuate feeding circuits","volume":"160","author":"Chen","year":"2015","journal-title":"Cell"},{"key":"10.1016\/j.physbeh.2021.113687_bib0032","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1038\/nature14260","article-title":"Hypothalamic POMC neurons promote cannabinoid-induced feeding","volume":"519","author":"Koch","year":"2015","journal-title":"Nature"},{"key":"10.1016\/j.physbeh.2021.113687_bib0033","doi-asserted-by":"crossref","first-page":"9048","DOI":"10.1523\/JNEUROSCI.22-20-09048.2002","article-title":"The catabolic action of insulin in the brain is mediated by melanocortins","volume":"22","author":"Benoit","year":"2002","journal-title":"J. Neurosci."},{"key":"10.1016\/j.physbeh.2021.113687_bib0034","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1046\/j.1365-2826.2001.00660.x","article-title":"Anorexic but not pyrogenic actions of interleukin-1 are modulated by central melanocortin-3\/4 receptors in the rat","volume":"13","author":"Lawrence","year":"2001","journal-title":"J. Neuroendocrinol."},{"key":"10.1016\/j.physbeh.2021.113687_bib0035","doi-asserted-by":"crossref","first-page":"15419","DOI":"10.1523\/JNEUROSCI.1449-15.2015","article-title":"Role of the Suprachiasmatic and Arcuate Nuclei in Diurnal Temperature Regulation in the Rat","volume":"35","author":"Guzman-Ruiz","year":"2015","journal-title":"J. Neurosci."}],"container-title":["Physiology &amp; Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0031938421003747?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0031938421003747?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T06:57:09Z","timestamp":1778655429000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0031938421003747"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3]]},"references-count":35,"alternative-id":["S0031938421003747"],"URL":"https:\/\/doi.org\/10.1016\/j.physbeh.2021.113687","relation":{},"ISSN":["0031-9384"],"issn-type":[{"value":"0031-9384","type":"print"}],"subject":[],"published":{"date-parts":[[2022,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Arcuate proopiomelanocortin is part of a novel neural connection for short-term low-degree of high ambient temperature effects on food intake.","name":"articletitle","label":"Article Title"},{"value":"Physiology & Behavior","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.physbeh.2021.113687","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"113687"}}