{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T03:46:02Z","timestamp":1789789562947,"version":"4.0.1"},"reference-count":35,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Physiology & Behavior"],"published-print":{"date-parts":[[2022,5]]},"DOI":"10.1016\/j.physbeh.2022.113726","type":"journal-article","created":{"date-parts":[[2022,2,2]],"date-time":"2022-02-02T22:50:27Z","timestamp":1643842227000},"page":"113726","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["Characterizing the effects of 2-phenylethylamine and coyote urine on unconditioned and conditioned defensive behaviors in adolescent male and female Long-Evans hooded rats"],"prefix":"10.1016","volume":"248","author":[{"given":"Nathan S.","family":"Pentkowski","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos","family":"Maestas-Olguin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriela","family":"Martinez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.physbeh.2022.113726_bib0001","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1037\/h0028589","article-title":"Species-specific defense reactions and avoidance learning","volume":"77","author":"Bolles","year":"1970","journal-title":"Psychol. Rev."},{"key":"10.1016\/j.physbeh.2022.113726_bib0002","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/S0149-7634(05)80069-7","article-title":"The characterization and modelling of antipredator defensive behavior","volume":"14","author":"Blanchard","year":"1990","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.physbeh.2022.113726_bib0003","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/j.neubiorev.2004.03.006","article-title":"Social threat perception and the evolution of paranoia","volume":"28","author":"Green","year":"2004","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.physbeh.2022.113726_bib0004","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1002\/da.20733","article-title":"Development of anxiety: the role of threat appraisal and fear learning","volume":"28","author":"Britton","year":"2011","journal-title":"Depress. Anxiety"},{"key":"10.1016\/j.physbeh.2022.113726_bib0005","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1016\/j.neubiorev.2010.10.016","article-title":"Risk assessment as an evolved threat detection and analysis process","volume":"35","author":"Blanchard","year":"2011","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.physbeh.2022.113726_bib0006","first-page":"19","article-title":"Defensive responses to predator threat in the rat and mouse","volume":"8","author":"Blanchard","year":"2005","journal-title":"Curr. Protoc. Neurosci."},{"key":"10.1016\/j.physbeh.2022.113726_bib0007","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1016\/j.neubiorev.2005.05.005","article-title":"The effects of predator odors in mammalian prey species: a review of field and laboratory studies","volume":"29","author":"Apfelbach","year":"2005","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.physbeh.2022.113726_bib0008","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/S0149-7634(01)00009-4","article-title":"Mouse defensive behaviors: pharmacological and behavioral assays for anxiety and panic","volume":"25","author":"Blanchard","year":"2001","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.physbeh.2022.113726_bib0009","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/S0014-2999(03)01276-7","article-title":"The mouse defense test battery: pharmacological and behavioral assays for anxiety and panic","volume":"463","author":"Blanchard","year":"2003","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.physbeh.2022.113726_bib0010","doi-asserted-by":"crossref","first-page":"1346","DOI":"10.1002\/ar.22745","article-title":"Of pheromones and kairomones: what receptors mediate innate emotional responses?","volume":"296","author":"Fortes-Marco","year":"2013","journal-title":"Anat. Rec. (Hoboken)"},{"key":"10.1016\/j.physbeh.2022.113726_bib0011","doi-asserted-by":"crossref","first-page":"21","DOI":"10.2307\/1294753","article-title":"Allomones and kairomones: transspecific chemical messengers","volume":"20","author":"Jr","year":"1970","journal-title":"Bioscience"},{"key":"10.1016\/j.physbeh.2022.113726_bib0012","doi-asserted-by":"crossref","first-page":"72","DOI":"10.3389\/fnbeh.2014.00072","article-title":"Olfactory systems and neural circuits that modulate predator odor fear","volume":"8","author":"Takahashi","year":"2014","journal-title":"Front. Behav. Neurosci."},{"key":"10.1016\/j.physbeh.2022.113726_bib0013","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1590\/S0100-879X2012007500042","article-title":"What ethologically based models have taught us about the neural systems underlying fear and anxiety","volume":"45","author":"Canteras","year":"2012","journal-title":"Braz. J. Med. Biol. Res."},{"key":"10.1016\/j.physbeh.2022.113726_bib0014","doi-asserted-by":"crossref","first-page":"1243","DOI":"10.1016\/j.neubiorev.2005.04.019","article-title":"Lesions of structures showing FOS expression to cat presentation: effects on responsivity to a Cat, Cat odor, and nonpredator threat","volume":"29","author":"Blanchard","year":"2005","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.physbeh.2022.113726_bib0015","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1016\/S0306-4522(01)00150-6","article-title":"When a rat smells a cat\": the distribution of Fos immunoreactivity in rat brain following exposure to a predatory odor","volume":"104","author":"Dielenberg","year":"2001","journal-title":"Neuroscience"},{"key":"10.1016\/j.physbeh.2022.113726_bib0016","doi-asserted-by":"crossref","first-page":"11235","DOI":"10.1073\/pnas.1103317108","article-title":"Detection and avoidance of a carnivore odor by prey","volume":"108","author":"Ferrero","year":"2011","journal-title":"Proc. Natl. Acad. Sci. U S A."},{"key":"10.1016\/j.physbeh.2022.113726_bib0017","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1007\/s10750-015-2508-6","article-title":"Behavioural response of adult sea lamprey (Petromyzon marinus) to predator and conspecific alarm cues: evidence of additive effects","volume":"767","author":"Di Rocco","year":"2015","journal-title":"Hydrobiologia"},{"key":"10.1016\/j.physbeh.2022.113726_bib0018","doi-asserted-by":"crossref","first-page":"1340","DOI":"10.1016\/j.cub.2015.03.026","article-title":"Innate predator odor aversion driven by parallel olfactory subsystems that converge in the ventromedial hypothalamus","volume":"25","author":"Perez-Gomez","year":"2015","journal-title":"Curr. Biol."},{"key":"10.1016\/j.physbeh.2022.113726_bib0019","doi-asserted-by":"crossref","DOI":"10.1016\/j.physbeh.2020.113210","article-title":"Coyote urine, but not 2-phenylethylamine, induces a complete profile of unconditioned anti-predator defensive behaviors","volume":"229","author":"Maestas-Olguin","year":"2021","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.physbeh.2022.113726_bib0020","doi-asserted-by":"crossref","first-page":"2617","DOI":"10.1007\/s10886-006-9186-9","article-title":"Exposure to urine of canids and felids, but not of herbivores, induces defensive behavior in laboratory rats","volume":"32","author":"Fendt","year":"2006","journal-title":"J. Chem. Ecol."},{"key":"10.1016\/j.physbeh.2022.113726_bib0021","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.bbr.2014.11.020","article-title":"Fox urine exposure induces avoidance behavior in rats and activates the amygdalar olfactory cortex","volume":"279","author":"Wernecke","year":"2015","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.physbeh.2022.113726_bib0022","doi-asserted-by":"crossref","first-page":"2744","DOI":"10.1038\/s41467-018-05090-y","article-title":"Anterior cingulate cortex and its input to the basolateral amygdala control innate fear response","volume":"9","author":"Jhang","year":"2018","journal-title":"Nat. Commun."},{"key":"10.1016\/j.physbeh.2022.113726_bib0023","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1016\/j.physbeh.2003.10.006","article-title":"Development of defensive behavior and conditioning to cat odor in the rat","volume":"80","author":"Hubbard","year":"2004","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.physbeh.2022.113726_bib0024","first-page":"587","volume":"25","author":"Blanchard","year":"2001","journal-title":"Cue and context conditioning of defensive behaviors to cat odor stimuli"},{"key":"10.1016\/j.physbeh.2022.113726_bib0025","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/S0006-8993(01)02227-2","article-title":"The cardiovascular and behavioral response to cat odor in rats: unconditioned and conditioned effects 1 1Published on the World Wide Web on 27 February 2001","volume":"897","author":"Dielenberg","year":"2001","journal-title":"Brain Res."},{"key":"10.1016\/j.physbeh.2022.113726_bib0026","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1016\/S0306-4522(01)00150-6","article-title":"When a rat smells a cat\u2019: the distribution of Fos immunoreactivity in rat brain following exposure to a predatory odor","volume":"104","author":"Dielenberg","year":"2001","journal-title":"Neuroscience"},{"key":"10.1016\/j.physbeh.2022.113726_bib0027","doi-asserted-by":"crossref","first-page":"11041","DOI":"10.1038\/s41598-018-28927-4","article-title":"Predator odour but not TMT induces 22-kHz ultrasonic vocalizations in rats that lead to defensive behaviours in conspecifics upon replay","volume":"8","author":"Fendt","year":"2018","journal-title":"Sci. Rep."},{"key":"10.1016\/j.physbeh.2022.113726_bib0028","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1037\/0735-7044.118.2.324","article-title":"Medial amygdala modulation of predator odor-induced unconditioned fear in the rat","volume":"118","author":"Li","year":"2004","journal-title":"Behav. Neurosci."},{"key":"10.1016\/j.physbeh.2022.113726_bib0029","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.physbeh.2018.04.028","article-title":"Effects of estrus cycle stage on defensive behavior in female Long-Evans hooded rats","volume":"194","author":"Pentkowski","year":"2018","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.physbeh.2022.113726_bib0030","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1002\/hipo.22105","article-title":"Differential roles of the dorsal and ventral hippocampus in predator odor contextual fear conditioning","volume":"23","author":"Wang","year":"2013","journal-title":"Hippocampus"},{"key":"10.1016\/j.physbeh.2022.113726_bib0031","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/S0149-7634(00)00014-2","article-title":"The adolescent brain and age-related behavioral manifestations","volume":"24","author":"Spear","year":"2000","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.physbeh.2022.113726_bib0032","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.yhbeh.2009.02.007","article-title":"Effects of acidic-astressin and ovine-CRF microinfusions into the ventral hippocampus on defensive behaviors in rats","volume":"56","author":"Pentkowski","year":"2009","journal-title":"Horm. Behav."},{"key":"10.1016\/j.physbeh.2022.113726_bib0033","doi-asserted-by":"crossref","first-page":"1563","DOI":"10.3758\/s13428-016-0787-0","article-title":"The simple video coder: a free tool for efficiently coding social video data","volume":"49","author":"Barto","year":"2017","journal-title":"Behav. Res. Methods"},{"key":"10.1016\/j.physbeh.2022.113726_bib0034","doi-asserted-by":"crossref","first-page":"2185","DOI":"10.1111\/j.1460-9568.2006.04754.x","article-title":"Effects of lesions to the dorsal and ventral hippocampus on defensive behaviors in rats","volume":"23","author":"Pentkowski","year":"2006","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.physbeh.2022.113726_bib0035","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1016\/S0149-7634(01)00043-4","article-title":"Cue and context conditioning of defensive behaviors to cat odor stimuli","volume":"25","author":"Blanchard","year":"2001","journal-title":"Neurosci. Biobehav. Rev."}],"container-title":["Physiology & Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0031938422000336?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0031938422000336?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T18:20:32Z","timestamp":1758478832000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0031938422000336"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5]]},"references-count":35,"alternative-id":["S0031938422000336"],"URL":"https:\/\/doi.org\/10.1016\/j.physbeh.2022.113726","relation":{},"ISSN":["0031-9384"],"issn-type":[{"value":"0031-9384","type":"print"}],"subject":[],"published":{"date-parts":[[2022,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Characterizing the effects of 2-phenylethylamine and coyote urine on unconditioned and conditioned defensive behaviors in adolescent male and female Long-Evans hooded rats","name":"articletitle","label":"Article Title"},{"value":"Physiology & Behavior","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.physbeh.2022.113726","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"113726"}}