{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T19:41:56Z","timestamp":1786995716752,"version":"build-2736575974"},"reference-count":21,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100000026","name":"National Institute on Drug Abuse","doi-asserted-by":"publisher","award":["P30DA013429"],"award-info":[{"award-number":["P30DA013429"]}],"id":[{"id":"10.13039\/100000026","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Physiology & Behavior"],"published-print":{"date-parts":[[2022,10]]},"DOI":"10.1016\/j.physbeh.2022.113933","type":"journal-article","created":{"date-parts":[[2022,7,26]],"date-time":"2022-07-26T12:35:30Z","timestamp":1658838930000},"page":"113933","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Energy drink produces aversive effects in planarians"],"prefix":"10.1016","volume":"255","author":[{"given":"Prateek","family":"Mokkarala","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aryan","family":"Shekarabi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonita","family":"Wiah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott M.","family":"Rawls","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.physbeh.2022.113933_bib0001","first-page":"468","article-title":"Energy drink consumption: beneficial and adverse health effects","volume":"9","author":"Alsunni","year":"2015","journal-title":"Int. J. Health Sci."},{"key":"10.1016\/j.physbeh.2022.113933_bib0002","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1007\/s13312-014-0441-9","article-title":"Energy drinks: potions of illusion","volume":"51","author":"Bedi","year":"2014","journal-title":"Indian Pediatr."},{"key":"10.1016\/j.physbeh.2022.113933_bib0003","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/0376-8716(87)90083-4","article-title":"The effects of food deprivation on the self-administration of psychoactive drugs","volume":"19","author":"De la Garza","year":"1987","journal-title":"Drug Alcohol Depend."},{"key":"10.1016\/j.physbeh.2022.113933_bib0004","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1068\/p6949","article-title":"Shedding light on photosensitive behaviour in brown planaria (Dugesia Tigrina)","volume":"40","author":"Davidson","year":"2011","journal-title":"Perception"},{"key":"10.1016\/j.physbeh.2022.113933_bib0005","doi-asserted-by":"crossref","DOI":"10.1007\/s00394-022-02874-3","article-title":"Risk or benefit? Side effects of caffeine supplementation in sport: a systematic review","author":"de Souza","year":"2022","journal-title":"Eur. J. Nutr."},{"key":"10.1016\/j.physbeh.2022.113933_bib0006","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/j.neuroscience.2018.06.029","article-title":"Mu opioid receptor agonist DAMGO produces place conditioning, abstinence-induced withdrawal, and naltrexone-dependent locomotor activation in planarians","volume":"386","author":"Dziedowiec","year":"2018","journal-title":"Neuroscience"},{"key":"10.1016\/j.physbeh.2022.113933_bib0007","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1007\/s00213-017-4801-8","article-title":"Dissociation of place preference and tolerance responses to sucrose using a dopamine antagonist in the planarian","volume":"235","author":"Mohammed Jawad","year":"2018","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.physbeh.2022.113933_bib0008","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0123310","article-title":"Guarana provides additional stimulation over caffeine alone in the planarian model","volume":"10","author":"Moustakas","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.physbeh.2022.113933_bib0009","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1016\/j.neuroscience.2008.03.026","article-title":"Identification of glutamic acid decarboxylase gene and distribution of GABAergic nervous system in the planarian Dugesia japonica","volume":"153","author":"Nishimura","year":"2008","journal-title":"Neuroscience"},{"key":"10.1016\/j.physbeh.2022.113933_bib0010","series-title":"The First brain: the Neuroscience of Planarians","author":"Pag\u00e1n","year":"2014"},{"key":"10.1016\/j.physbeh.2022.113933_bib0011","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.ejphar.2009.05.022","article-title":"A cembranoid from tobacco prevents the expression of nicotine-induced withdrawal behavior in planarian worms","volume":"615","author":"Pag\u00e1n","year":"2009","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.physbeh.2022.113933_bib0012","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.neuroscience.2012.01.019","article-title":"Mephedrone (\"bath salt\") pharmacology: insights from invertebrates","volume":"208","author":"Ramoz","year":"2012","journal-title":"Neuroscience"},{"key":"10.1016\/j.physbeh.2022.113933_bib0013","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1016\/j.drugalcdep.2011.04.001","article-title":"Nicotine behavioral pharmacology: clues from planarians","volume":"118","author":"Rawls","year":"2011","journal-title":"Drug Alcohol Depend"},{"key":"10.1016\/j.physbeh.2022.113933_bib0014","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1097\/FBP.0b013e32833b0098","article-title":"First evidence that drugs of abuse produce behavioral sensitization and cross sensitization in planarians","volume":"21","author":"Rawls","year":"2010","journal-title":"Behav. Pharmacol."},{"key":"10.1016\/j.physbeh.2022.113933_bib0015","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.ejphar.2008.01.012","article-title":"Parthenolide prevents the expression of cocaine-induced withdrawal behavior in planarians","volume":"583","author":"Rowlands","year":"2008","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.physbeh.2022.113933_bib0016","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1177\/1559827618803069","article-title":"Risk of energy drink consumption to adolescent health","volume":"13","author":"Ruiz","year":"2018","journal-title":"Am. J. Lifestyle Med."},{"key":"10.1016\/j.physbeh.2022.113933_bib0017","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.neulet.2008.04.086","article-title":"Withdrawal-like behavior in planarians is dependent on drug exposure duration","volume":"439","author":"Sacavage","year":"2008","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.physbeh.2022.113933_bib0018","doi-asserted-by":"crossref","DOI":"10.1016\/j.physbeh.2021.113499","article-title":"Kratom pharmacology: clues from planarians exposed to mitragynine","volume":"239","author":"Uddin","year":"2021","journal-title":"Physiol. Behav."},{"issue":"Pt 2","key":"10.1016\/j.physbeh.2022.113933_bib0019","article-title":"Caffeine as a contaminant of concern: a review on concentrations and impacts in marine coastal systems","volume":"286","author":"Vieira","year":"2022","journal-title":"Chemosphere"},{"key":"10.1016\/j.physbeh.2022.113933_bib0020","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1016\/j.jneumeth.2017.10.010","article-title":"PLDT (planarian light\/dark test): an invertebrate assay to quantify defensive responding and study anxiety-like effects","volume":"293","author":"Zewde","year":"2018","journal-title":"J. Neurosci. Methods"},{"key":"10.1016\/j.physbeh.2022.113933_bib0021","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.physbeh.2013.02.002","article-title":"Sucrose produces withdrawal and dopamine-sensitive reinforcing effects in planarians","volume":"112-113","author":"Zhang","year":"2013","journal-title":"Physiol. Behav."}],"container-title":["Physiology & Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0031938422002396?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0031938422002396?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T18:21:42Z","timestamp":1758478902000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0031938422002396"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10]]},"references-count":21,"alternative-id":["S0031938422002396"],"URL":"https:\/\/doi.org\/10.1016\/j.physbeh.2022.113933","relation":{},"ISSN":["0031-9384"],"issn-type":[{"value":"0031-9384","type":"print"}],"subject":[],"published":{"date-parts":[[2022,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Energy drink produces aversive effects in planarians","name":"articletitle","label":"Article Title"},{"value":"Physiology & Behavior","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.physbeh.2022.113933","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"113933"}}