{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T23:35:20Z","timestamp":1790724920077,"version":"4.1.0"},"reference-count":80,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,12,30]],"date-time":"2024-12-30T00:00:00Z","timestamp":1735516800000},"content-version":"am","delay-in-days":304,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100000055","name":"National Institute on Deafness and Other Communication Disorders","doi-asserted-by":"publisher","award":["P30 DC011735"],"award-info":[{"award-number":["P30 DC011735"]}],"id":[{"id":"10.13039\/100000055","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000055","name":"National Institute on Deafness and Other Communication Disorders","doi-asserted-by":"publisher","award":["R01DC018042"],"award-info":[{"award-number":["R01DC018042"]}],"id":[{"id":"10.13039\/100000055","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100019680","name":"Monell Chemical Senses Center","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100019680","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007418","name":"Ajinomoto Pharmaceuticals","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007418","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000052","name":"National Institutes of Health Office of the Director","doi-asserted-by":"publisher","award":["G20OD020296"],"award-info":[{"award-number":["G20OD020296"]}],"id":[{"id":"10.13039\/100000052","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Physiology &amp; Behavior"],"published-print":{"date-parts":[[2024,3]]},"DOI":"10.1016\/j.physbeh.2023.114446","type":"journal-article","created":{"date-parts":[[2023,12,19]],"date-time":"2023-12-19T21:13:49Z","timestamp":1703020429000},"page":"114446","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["Chronic social defeat stress broadly inhibits gene expression in the peripheral taste system and alters taste responses in mice"],"prefix":"10.1016","volume":"275","author":[{"given":"Katelyn","family":"Tu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jidong J.","family":"Tan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Loza","family":"Markos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cameron","family":"Cloud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minliang","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoki","family":"Hayashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nancy E.","family":"Rawson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert F.","family":"Margolskee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4130-8741","authenticated-orcid":false,"given":"Hong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.physbeh.2023.114446_bib0001","first-page":"255","article-title":"Stress and eating behaviors","volume":"38","author":"Yau","year":"2013","journal-title":"Minerva. Endocrinol."},{"key":"10.1016\/j.physbeh.2023.114446_bib0002","first-page":"381","article-title":"Stress exposure, food intake and emotional state","volume":"18","author":"Ulrich-Lai","year":"2015","journal-title":"Stress"},{"key":"10.1016\/j.physbeh.2023.114446_bib0003","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.neubiorev.2017.01.026","article-title":"Stress, overeating, and obesity: insights from human studies and preclinical models","volume":"76","author":"Razzoli","year":"2017","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.physbeh.2023.114446_bib0004","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1016\/j.jaci.2013.09.007","article-title":"The biology of the glucocorticoid receptor: new signaling mechanisms in health and disease","volume":"132","author":"Oakley","year":"2013","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.physbeh.2023.114446_bib0005","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1007\/s11886-017-0919-x","article-title":"Psychological stress, inflammation, and coronary heart disease","volume":"19","author":"Wirtz","year":"2017","journal-title":"Curr. Cardiol. Rep."},{"key":"10.1016\/j.physbeh.2023.114446_bib0006","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1038\/nrn.2017.68","article-title":"Taste buds: cells, signals and synapses","volume":"18","author":"Roper","year":"2017","journal-title":"Nat. rev. Neurosci."},{"key":"10.1016\/j.physbeh.2023.114446_bib0007","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1038\/ng0501-58","article-title":"Tas1r3, encoding a new candidate taste receptor, is allelic to the sweet responsiveness locus Sac","volume":"28","author":"Max","year":"2001","journal-title":"Nat. Genet."},{"key":"10.1016\/j.physbeh.2023.114446_bib0008","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1038\/87440","article-title":"A candidate taste receptor gene near a sweet taste locus","volume":"4","author":"Montmayeur","year":"2001","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.physbeh.2023.114446_bib0009","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1038\/nature726","article-title":"An amino-acid taste receptor","volume":"416","author":"Nelson","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.physbeh.2023.114446_bib0010","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1016\/S0092-8674(00)80705-9","article-title":"A novel family of mammalian taste receptors","volume":"100","author":"Adler","year":"2000","journal-title":"Cell"},{"key":"10.1016\/j.physbeh.2023.114446_bib0011","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1016\/S0092-8674(00)80706-0","article-title":"T2Rs function as bitter taste receptors","volume":"100","author":"Chandrashekar","year":"2000","journal-title":"Cell"},{"key":"10.1016\/j.physbeh.2023.114446_bib0012","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1038\/35007072","article-title":"A family of candidate taste receptors in human and mouse","volume":"404","author":"Matsunami","year":"2000","journal-title":"Nature"},{"key":"10.1016\/j.physbeh.2023.114446_bib0013","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1038\/nature08783","article-title":"The cells and peripheral representation of sodium taste in mice","volume":"464","author":"Chandrashekar","year":"2010","journal-title":"Nature"},{"key":"10.1016\/j.physbeh.2023.114446_bib0014","doi-asserted-by":"crossref","DOI":"10.1016\/j.cub.2019.08.077","article-title":"Cellular and neural responses to sour stimuli require the proton channel Otop1","volume":"29","author":"Teng","year":"2019","journal-title":"Curr. Biol."},{"key":"10.1016\/j.physbeh.2023.114446_bib0015","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1126\/science.aao3264","article-title":"An evolutionarily conserved gene family encodes proton-selective ion channels","volume":"359","author":"Tu","year":"2018","journal-title":"Science"},{"key":"10.1016\/j.physbeh.2023.114446_bib0016","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1194\/jlr.M055202","article-title":"The oral lipid sensor GPR120 is not indispensable for the orosensory detection of dietary lipids in mice","volume":"56","author":"Ancel","year":"2015","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.physbeh.2023.114446_bib0017","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.plipres.2013.11.001","article-title":"Cell signaling mechanisms of oro-gustatory detection of dietary fat: advances and challenges","volume":"53","author":"Gilbertson","year":"2014","journal-title":"Prog. Lipid Res."},{"key":"10.1016\/j.physbeh.2023.114446_bib0018","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1038\/357563a0","article-title":"Gustducin is a taste-cell-specific G protein closely related to the transducins","volume":"357","author":"McLaughlin","year":"1992","journal-title":"Nature"},{"key":"10.1016\/j.physbeh.2023.114446_bib0019","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1038\/15981","article-title":"Ggamma13 colocalizes with gustducin in taste receptor cells and mediates IP3 responses to bitter denatonium","volume":"2","author":"Huang","year":"1999","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.physbeh.2023.114446_bib0020","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.1038\/nn952","article-title":"A transient receptor potential channel expressed in taste receptor cells","volume":"5","author":"Perez","year":"2002","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.physbeh.2023.114446_bib0021","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/S0092-8674(03)00071-0","article-title":"Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways","volume":"112","author":"Zhang","year":"2003","journal-title":"Cell"},{"key":"10.1016\/j.physbeh.2023.114446_bib0022","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1038\/nature11906","article-title":"CALHM1 ion channel mediates purinergic neurotransmission of sweet, bitter and umami tastes","volume":"495","author":"Taruno","year":"2013","journal-title":"Nature"},{"key":"10.1016\/j.physbeh.2023.114446_bib0023","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/j.neuron.2018.03.043","article-title":"CALHM3 is essential for rapid ion channel-mediated purinergic neurotransmission of GPCR-mediated tastes","volume":"98","author":"Ma","year":"2018","journal-title":"Neuron"},{"issue":"Suppl 1","key":"10.1016\/j.physbeh.2023.114446_bib0024","doi-asserted-by":"crossref","first-page":"i54","DOI":"10.1093\/chemse\/bjh110","article-title":"Cell types and lineages in taste buds","volume":"30","author":"Finger","year":"2005","journal-title":"Chem. Senses."},{"key":"10.1016\/j.physbeh.2023.114446_bib0025","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1186\/1471-2202-11-72","article-title":"Lipopolysaccharide-induced inflammation attenuates taste progenitor cell proliferation and shortens the life span of taste bud cells","volume":"11","author":"Cohn","year":"2010","journal-title":"BMC Neurosci."},{"key":"10.1016\/j.physbeh.2023.114446_bib0026","doi-asserted-by":"crossref","first-page":"e35588","DOI":"10.1371\/journal.pone.0035588","article-title":"Defects in the peripheral taste structure and function in the MRL\/lpr mouse model of autoimmune disease","volume":"7","author":"Kim","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.physbeh.2023.114446_bib0027","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1093\/chemse\/bjt059","article-title":"Taste bud homeostasis in health, disease, and aging","volume":"39","author":"Feng","year":"2014","journal-title":"Chem. Senses."},{"key":"10.1016\/j.physbeh.2023.114446_bib0028","doi-asserted-by":"crossref","first-page":"15069","DOI":"10.1073\/pnas.0706890104","article-title":"Gut-expressed gustducin and taste receptors regulate secretion of glucagon-like peptide-1","volume":"104","author":"Jang","year":"2007","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.physbeh.2023.114446_bib0029","doi-asserted-by":"crossref","first-page":"15075","DOI":"10.1073\/pnas.0706678104","article-title":"T1R3 and gustducin in gut sense sugars to regulate expression of Na+-glucose cotransporter 1","volume":"104","author":"Margolskee","year":"2007","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.physbeh.2023.114446_bib0030","doi-asserted-by":"crossref","DOI":"10.3945\/ajcn.2009.27462T","article-title":"Taste signaling elements expressed in gut enteroendocrine cells regulate nutrient-responsive secretion of gut hormones","volume":"90","author":"Kokrashvili","year":"2009","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1016\/j.physbeh.2023.114446_bib0031","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.bbi.2018.04.010","article-title":"Aggravated gut inflammation in mice lacking the taste signaling protein alpha-gustducin","volume":"71","author":"Feng","year":"2018","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.physbeh.2023.114446_bib0032","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1126\/science.aaf1648","article-title":"Tuft cells, taste-chemosensory cells, orchestrate parasite type 2 immunity in the gut","volume":"351","author":"Howitt","year":"2016","journal-title":"Science"},{"key":"10.1016\/j.physbeh.2023.114446_bib0033","article-title":"Infection by the parasitic helminth Trichinella spiralis activates a Tas2r-mediated signaling pathway in intestinal tuft cells","author":"Luo","year":"2019","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.physbeh.2023.114446_bib0034","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1254\/jphs.09R16FM","article-title":"New frontiers in gut nutrient sensor research: luminal glutamate-sensing cells in rat gastric mucosa","volume":"112","author":"Nakamura","year":"2010","journal-title":"J. Pharmacol. Sci."},{"key":"10.1016\/j.physbeh.2023.114446_bib0035","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1007\/164_2021_468","article-title":"Immune regulatory roles of cells expressing taste signaling elements in nongustatory tissues","volume":"275","author":"Wang","year":"2022","journal-title":"Handb. Exp. Pharmacol."},{"key":"10.1016\/j.physbeh.2023.114446_bib0036","doi-asserted-by":"crossref","first-page":"G271","DOI":"10.1152\/ajpgi.00074.2012","article-title":"Sensing of amino acids by the gut-expressed taste receptor T1R1-T1R3 stimulates CCK secretion","volume":"304","author":"Daly","year":"2013","journal-title":"Am. j. physiol. Gastrointest. liver physiol."},{"key":"10.1016\/j.physbeh.2023.114446_bib0037","doi-asserted-by":"crossref","first-page":"2094","DOI":"10.1073\/pnas.1011508108","article-title":"Bitter taste receptors and alpha-gustducin regulate the secretion of ghrelin with functional effects on food intake and gastric emptying","volume":"108","author":"Janssen","year":"2011","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.physbeh.2023.114446_bib0038","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1111\/j.1469-8986.2011.01289.x","article-title":"Exposure to acute stress is associated with attenuated sweet taste","volume":"49","author":"Al'Absi","year":"2012","journal-title":"Psychophysiology"},{"key":"10.1016\/j.physbeh.2023.114446_bib0039","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1093\/chemse\/bjs075","article-title":"Effect of acute stress on taste perception: in relation with baseline anxiety level and body weight","volume":"38","author":"Ileri-Gurel","year":"2013","journal-title":"Chem. Senses."},{"key":"10.1016\/j.physbeh.2023.114446_bib0040","doi-asserted-by":"crossref","first-page":"12664","DOI":"10.1523\/JNEUROSCI.3459-06.2006","article-title":"Human taste thresholds are modulated by serotonin and noradrenaline","volume":"26","author":"Heath","year":"2006","journal-title":"J. Neurosci."},{"key":"10.1016\/j.physbeh.2023.114446_bib0041","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.neulet.2014.04.047","article-title":"Expression and nuclear translocation of glucocorticoid receptors in type 2 taste receptor cells","volume":"571","author":"Parker","year":"2014","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.physbeh.2023.114446_bib0042","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.neulet.2010.09.055","article-title":"Chronic restraint stress in rats suppresses sweet and umami taste responses and lingual expression of T1R3 mRNA","volume":"486","author":"Okamoto","year":"2010","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.physbeh.2023.114446_bib0043","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.bbrc.2021.09.063","article-title":"Subchronic and mild social defeat stress downregulates peripheral expression of sweet and umami taste receptors in male mice","volume":"579","author":"Yoshida","year":"2021","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.physbeh.2023.114446_bib0044","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1038\/nprot.2011.361","article-title":"A standardized protocol for repeated social defeat stress in mice","volume":"6","author":"Golden","year":"2011","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.physbeh.2023.114446_bib0045","doi-asserted-by":"crossref","first-page":"10703","DOI":"10.1523\/JNEUROSCI.3102-07.2007","article-title":"Inflammation activates the interferon signaling pathways in taste bud cells","volume":"27","author":"Wang","year":"2007","journal-title":"J. Neurosci."},{"key":"10.1016\/j.physbeh.2023.114446_bib0046","doi-asserted-by":"crossref","first-page":"2689","DOI":"10.1523\/JNEUROSCI.3074-13.2014","article-title":"Interleukin-10 is produced by a specific subset of taste receptor cells and critical for maintaining structural integrity of mouse taste buds","volume":"34","author":"Feng","year":"2014","journal-title":"J. Neurosci."},{"key":"10.1016\/j.physbeh.2023.114446_bib0047","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2-\u0394\u0394Ct method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"10.1016\/j.physbeh.2023.114446_bib0048","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1038\/nn.2139","article-title":"The orexigenic hormone ghrelin defends against depressive symptoms of chronic stress","volume":"11","author":"Lutter","year":"2008","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.physbeh.2023.114446_bib0049","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/j.bbr.2014.05.040","article-title":"Subchronic and mild social defeat stress accelerates food intake and body weight gain with polydipsia-like features in mice","volume":"270","author":"Goto","year":"2014","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.physbeh.2023.114446_bib0050","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1111\/j.1467-789X.2006.00270.x","article-title":"The role of leptin and ghrelin in the regulation of food intake and body weight in humans: a review","volume":"8","author":"Klok","year":"2007","journal-title":"Obes. Rev."},{"key":"10.1016\/j.physbeh.2023.114446_bib0051","doi-asserted-by":"crossref","first-page":"8376","DOI":"10.1523\/JNEUROSCI.0496-10.2010","article-title":"Taste preference for fatty acids is mediated by GPR40 and GPR120","volume":"30","author":"Cartoni","year":"2010","journal-title":"J. Neurosci."},{"key":"10.1016\/j.physbeh.2023.114446_bib0052","doi-asserted-by":"crossref","first-page":"e24014","DOI":"10.1371\/journal.pone.0024014","article-title":"The lipid-sensor candidates CD36 and GPR120 are differentially regulated by dietary lipids in mouse taste buds: impact on spontaneous fat preference","volume":"6","author":"Martin","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.physbeh.2023.114446_bib0053","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1007\/164_2021_437","article-title":"Cellular and molecular mechanisms of fat taste perception","volume":"275","author":"Hichami","year":"2022","journal-title":"Handb. Exp. Pharmacol."},{"key":"10.1016\/j.physbeh.2023.114446_bib0054","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1038\/nature05084","article-title":"The cells and logic for mammalian sour taste detection","volume":"442","author":"Huang","year":"2006","journal-title":"Nature"},{"key":"10.1016\/j.physbeh.2023.114446_bib0055","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/bs.ctdb.2014.11.012","article-title":"Developing and regenerating a sense of taste","volume":"111","author":"Barlow","year":"2015","journal-title":"Curr. Top. Dev. Biol."},{"key":"10.1016\/j.physbeh.2023.114446_bib0056","doi-asserted-by":"crossref","first-page":"1286","DOI":"10.1002\/dvdy.24121","article-title":"Sonic hedgehog-expressing basal cells are general post-mitotic precursors of functional taste receptor cells","volume":"243","author":"Miura","year":"2014","journal-title":"Dev. Dyn."},{"key":"10.1016\/j.physbeh.2023.114446_bib0057","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1093\/chemse\/bjh248","article-title":"A strong nerve dependence of sonic hedgehog expression in basal cells in mouse taste bud and an autonomous transcriptional control of genes in differentiated taste cells","volume":"29","author":"Miura","year":"2004","journal-title":"Chem. Senses."},{"key":"10.1016\/j.physbeh.2023.114446_bib0058","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1002\/cne.21899","article-title":"Expression of the voltage-gated potassium channel KCNQ1 in mammalian taste bud cells and the effect of its null-mutation on taste preferences","volume":"512","author":"Wang","year":"2009","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.physbeh.2023.114446_bib0059","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1093\/chemse\/bjl016","article-title":"Taste receptor cells express voltage-dependent potassium channels in a cell age-specific manner","volume":"31","author":"Ohmoto","year":"2006","journal-title":"Chem. Senses."},{"key":"10.1016\/j.physbeh.2023.114446_bib0060","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1093\/chemse\/bjg062","article-title":"Taste sensitivities to PROP and PTC vary independently in mice","volume":"28","author":"Nelson","year":"2003","journal-title":"Chem. Senses."},{"key":"10.1016\/j.physbeh.2023.114446_bib0061","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.neubiorev.2015.10.006","article-title":"Defeat stress in rodents: from behavior to molecules","volume":"59","author":"Hammels","year":"2015","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.physbeh.2023.114446_bib0062","doi-asserted-by":"crossref","first-page":"1421","DOI":"10.1016\/j.neuroscience.2010.05.021","article-title":"Characterization of the expression pattern of adrenergic receptors in rat taste buds","volume":"169","author":"Zhang","year":"2010","journal-title":"Neuroscience"},{"key":"10.1016\/j.physbeh.2023.114446_bib0063","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1038\/s41586-020-1935-3","article-title":"Hyperactivation of sympathetic nerves drives depletion of melanocyte stem cells","volume":"577","author":"Zhang","year":"2020","journal-title":"Nature"},{"key":"10.1016\/j.physbeh.2023.114446_bib0064","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1016\/j.biopsych.2009.12.003","article-title":"A beta3-adrenergic-leptin-melanocortin circuit regulates behavioral and metabolic changes induced by chronic stress","volume":"67","author":"Chuang","year":"2010","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.physbeh.2023.114446_bib0065","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.bbr.2010.07.014","article-title":"Different susceptibility to social defeat stress of BalbC and C57BL6\/J mice","volume":"216","author":"Razzoli","year":"2011","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.physbeh.2023.114446_bib0066","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1021\/pr501044k","article-title":"Plasma and liver metabolic profiles in mice subjected to subchronic and mild social defeat stress","volume":"14","author":"Goto","year":"2015","journal-title":"J. Proteome Res."},{"key":"10.1016\/j.physbeh.2023.114446_bib0067","first-page":"11","article-title":"Assessing the effects of stress on feeding behaviors in laboratory mice","author":"Francois","year":"2022","journal-title":"eLife"},{"key":"10.1016\/j.physbeh.2023.114446_bib0068","doi-asserted-by":"crossref","first-page":"R1138","DOI":"10.1152\/ajpregu.2000.279.3.R1138","article-title":"Single exposure to stressors causes long-lasting, stress-dependent reduction of food intake in rats","volume":"279","author":"Valles","year":"2000","journal-title":"Am. J. Physiol. Regul., Integr. Comp. Physiol."},{"key":"10.1016\/j.physbeh.2023.114446_bib0069","first-page":"R1928","article-title":"Effect of repeated stress on body weight and body composition of rats fed low- and high-fat diets","volume":"275","author":"Harris","year":"1998","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.physbeh.2023.114446_bib0070","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1016\/j.physbeh.2003.12.002","article-title":"Metabolic and endocrine consequences of social stress in a visible burrow system","volume":"80","author":"Tamashiro","year":"2004","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.physbeh.2023.114446_bib0071","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.physbeh.2017.01.021","article-title":"The visible burrow system: a view from across the hall","volume":"178","author":"Herman","year":"2017","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.physbeh.2023.114446_bib0072","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.cophys.2020.12.006","article-title":"Sour taste: receptors, cells and circuits","volume":"20","author":"Liman","year":"2021","journal-title":"Curr Opin Physiol."},{"key":"10.1016\/j.physbeh.2023.114446_bib0073","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1098\/rstb.2006.1853","article-title":"Psychophysics of sweet and fat perception in obesity: problems, solutions and new perspectives","volume":"361","author":"Bartoshuk","year":"2006","journal-title":"Philos. Trans. R. Soc. Lond., B, Biol. Sci."},{"key":"10.1016\/j.physbeh.2023.114446_bib0074","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.physbeh.2008.04.023","article-title":"Oral sensory phenotype identifies level of sugar and fat required for maximal liking","volume":"95","author":"Hayes","year":"2008","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.physbeh.2023.114446_bib0075","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1136\/archdischild-2011-301189","article-title":"Differences in taste sensitivity between obese and non-obese children and adolescents","volume":"97","author":"Overberg","year":"2012","journal-title":"Arch. Dis. Child."},{"key":"10.1016\/j.physbeh.2023.114446_bib0076","doi-asserted-by":"crossref","DOI":"10.1155\/2019\/2978026","article-title":"General decrease of taste sensitivity is related to increase of bmi: a simple method to monitor eating behavior","author":"Vignini","year":"2019","journal-title":"Dis. Markers"},{"key":"10.1016\/j.physbeh.2023.114446_bib0077","doi-asserted-by":"crossref","DOI":"10.3389\/fpsyg.2021.597704","article-title":"Longitudinal associations between taste sensitivity, taste liking, dietary intake and BMI in adolescents","volume":"12","author":"Papantoni","year":"2021","journal-title":"Front Psychol"},{"key":"10.1016\/j.physbeh.2023.114446_bib0078","doi-asserted-by":"crossref","first-page":"509","DOI":"10.4093\/dmj.2020.0058","article-title":"Consequences of obesity on the sense of taste: taste buds as treatment targets?","volume":"44","author":"Rohde","year":"2020","journal-title":"Diabetes Metab. J"},{"key":"10.1016\/j.physbeh.2023.114446_bib0079","doi-asserted-by":"crossref","first-page":"432","DOI":"10.3389\/fped.2019.00432","article-title":"Stress triggers flare of inflammatory bowel disease in children and adults","volume":"7","author":"Sun","year":"2019","journal-title":"Front Pediatr"},{"key":"10.1016\/j.physbeh.2023.114446_bib0080","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.immuni.2021.12.013","article-title":"Inflammation in obesity, diabetes, and related disorders","volume":"55","author":"Rohm","year":"2022","journal-title":"Immunity"}],"container-title":["Physiology &amp; Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0031938423003712?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0031938423003712?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T18:25:39Z","timestamp":1758479139000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0031938423003712"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3]]},"references-count":80,"alternative-id":["S0031938423003712"],"URL":"https:\/\/doi.org\/10.1016\/j.physbeh.2023.114446","relation":{},"ISSN":["0031-9384"],"issn-type":[{"value":"0031-9384","type":"print"}],"subject":[],"published":{"date-parts":[[2024,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Chronic social defeat stress broadly inhibits gene expression in the peripheral taste system and alters taste responses in mice","name":"articletitle","label":"Article Title"},{"value":"Physiology & Behavior","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.physbeh.2023.114446","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"114446"}}