{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T19:41:59Z","timestamp":1786995719204,"version":"build-2736575974"},"reference-count":98,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100002742","name":"Banaras Hindu University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002742","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Physiology & Behavior"],"published-print":{"date-parts":[[2026,1]]},"DOI":"10.1016\/j.physbeh.2025.115149","type":"journal-article","created":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T17:16:54Z","timestamp":1761671814000},"page":"115149","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Impact of high sugar intake on neurobehavioral, oxidative, and hepatic integrity in mice exposed to simulated chronic jetlag\/shiftwork"],"prefix":"10.1016","volume":"303","author":[{"given":"Madhumita","family":"Mishra","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajesh","family":"Gupta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vineetkumar","family":"Pillai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1559-7914","authenticated-orcid":false,"given":"Muniyandi","family":"Singaravel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"8","key":"10.1016\/j.physbeh.2025.115149_bib0001","first-page":"1068","article-title":"Circadian rhythm, lifestyle and health: a narrative review","volume":"47","author":"Farhud","year":"2018","journal-title":"Iran. J. Public Health"},{"key":"10.1016\/j.physbeh.2025.115149_bib0002","doi-asserted-by":"crossref","DOI":"10.3389\/fnetp.2021.803011","article-title":"Synergies of multiple zeitgebers tune entrainment","volume":"1","author":"Grabe","year":"2022","journal-title":"Front. Netw. Physiol."},{"issue":"1","key":"10.1016\/j.physbeh.2025.115149_bib0003","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-019-56323-z","article-title":"Differentiating external zeitgeber impact on peripheral circadian clock resetting","volume":"9","author":"Heyde","year":"2019","journal-title":"Sci. Rep."},{"issue":"7358","key":"10.1016\/j.physbeh.2025.115149_bib0004","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1038\/nature10206","article-title":"Photoentrainment and pupillary light reflex are mediated by distinct populations of ipRGCs","volume":"476","author":"Chen","year":"2011","journal-title":"Nature"},{"issue":"1","key":"10.1016\/j.physbeh.2025.115149_bib0005","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1038\/s41392-022-00899-y","article-title":"Molecular regulations of circadian rhythm and implications for physiology and diseases","volume":"7","author":"Fagiani","year":"2022","journal-title":"Signal. Transduct. Target. Ther."},{"issue":"3","key":"10.1016\/j.physbeh.2025.115149_bib0006","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1007\/s11818-019-00215-x","article-title":"Effects of light on human circadian rhythms, sleep and mood","volume":"23","author":"Blume","year":"2019","journal-title":"Somnologie"},{"issue":"11","key":"10.1016\/j.physbeh.2025.115149_bib0007","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.1701528","article-title":"Artificially lit surface of Earth at night increasing in radiance and extent","volume":"3","author":"Kyba","year":"2017","journal-title":"Sci. Adv."},{"key":"10.1016\/j.physbeh.2025.115149_bib0008","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/j.ejca.2022.06.007","article-title":"Exposure to artificial light at night: a common link for obesity and cancer?","volume":"173","author":"Muscogiuri","year":"2022","journal-title":"Eur. J. Cancer"},{"issue":"7","key":"10.1016\/j.physbeh.2025.115149_bib0009","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0270480","article-title":"Shift-work sleep disorder among health care workers at public hospitals, the case of Sidama national regional state, Ethiopia: a multicenter cross-sectional study","volume":"17","author":"Adane","year":"2022","journal-title":"PLoS One"},{"key":"10.1016\/j.physbeh.2025.115149_bib0010","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1016\/j.scitotenv.2017.07.056","article-title":"Health consequences of electric lighting practices in the modern world: a report on the national toxicology program's workshop on shift work at night, artificial light at night, and circadian disruption","volume":"607","author":"Lunn","year":"2017","journal-title":"Sci. Total Environ."},{"issue":"2","key":"10.1016\/j.physbeh.2025.115149_bib0011","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1177\/074873048900400207","article-title":"Different mechanisms of phase delays and phase advances of the circadian rhythm in rat pineal N-acetyltransferase activity","volume":"4","author":"Illnerov\u00e1","year":"1989","journal-title":"J. Biol. Rhythms"},{"key":"10.1016\/j.physbeh.2025.115149_bib0012","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.jpsychires.2021.05.045","article-title":"Shift work and incidence of psychiatric disorders: the Danish Nurse Cohort study","volume":"139","author":"J\u00f8rgensen","year":"2021","journal-title":"J. Psychiatr. Res."},{"issue":"17","key":"10.1016\/j.physbeh.2025.115149_bib0013","doi-asserted-by":"crossref","first-page":"7326","DOI":"10.1523\/JNEUROSCI.22-17-07326.2002","article-title":"Differential resynchronisation of circadian clock gene expression within the suprachiasmatic nuclei of mice subjected to experimental jet lag","volume":"22","author":"Reddy","year":"2002","journal-title":"J. Neurosci."},{"issue":"8","key":"10.1016\/j.physbeh.2025.115149_bib0014","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.1080\/07420528.2016.1184678","article-title":"Circadian disruption: new clinical perspective of disease pathology and basis for chronotherapeutic intervention","volume":"33","author":"Smolensky","year":"2016","journal-title":"Chronobiol. Int."},{"issue":"4","key":"10.1016\/j.physbeh.2025.115149_bib0015","doi-asserted-by":"crossref","first-page":"557","DOI":"10.3109\/07420528.2014.986682","article-title":"Dim light at night increases body mass of female mice","volume":"32","author":"Aubrecht","year":"2015","journal-title":"Chronobiol. Int."},{"key":"10.1016\/j.physbeh.2025.115149_bib0016","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2022.115049","article-title":"Outdoor artificial light at night and human health: a review of epidemiological studies","volume":"218","author":"Bo\u017cejko","year":"2023","journal-title":"Environ. Res."},{"issue":"3","key":"10.1016\/j.physbeh.2025.115149_bib0017","doi-asserted-by":"crossref","first-page":"zsac130","DOI":"10.1093\/sleep\/zsac130","article-title":"Light at night in older age is associated with obesity, diabetes, and hypertension","volume":"46","author":"Kim","year":"2023","journal-title":"Sleep"},{"issue":"1","key":"10.1016\/j.physbeh.2025.115149_bib0018","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1080\/07420520802694020","article-title":"Global co-distribution of light at night (LAN) and cancers of prostate, colon, and lung in men","volume":"26","author":"Kloog","year":"2009","journal-title":"Chronobiol. Int."},{"issue":"12","key":"10.1016\/j.physbeh.2025.115149_bib0019","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2113290119","article-title":"Light exposure during sleep impairs cardiometabolic function","volume":"119","author":"Mason","year":"2022","journal-title":"Proc. Natl. Acad. Sci."},{"issue":"1","key":"10.1016\/j.physbeh.2025.115149_bib0020","doi-asserted-by":"crossref","first-page":"e1017","DOI":"10.1038\/tp.2016.262","article-title":"Timing of light exposure affects mood and brain circuits","volume":"7","author":"Bedrosian","year":"2017","journal-title":"Transl. Psychiatry"},{"issue":"1","key":"10.1016\/j.physbeh.2025.115149_bib0021","doi-asserted-by":"crossref","first-page":"305","DOI":"10.3390\/ijms23010305","article-title":"Associations between melatonin, neuroinflammation, and brain alterations in depression","volume":"23","author":"Won","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.physbeh.2025.115149_bib0022","article-title":"The relationship of shift work disorder with symptoms of depression, anxiety, and stress","volume":"15","author":"Chang","year":"2024","journal-title":"J. Affect. Disord. Rep."},{"issue":"12","key":"10.1016\/j.physbeh.2025.115149_bib0023","doi-asserted-by":"crossref","first-page":"1532","DOI":"10.1016\/j.sleep.2015.09.007","article-title":"Shift work disorder, depression, and anxiety in the transition to rotating shifts: the role of sleep reactivity","volume":"16","author":"Kalmbach","year":"2015","journal-title":"Sleep Med."},{"key":"10.1016\/j.physbeh.2025.115149_bib0024","article-title":"Effects of factors related to shift work on depression and anxiety in nurses","volume":"10","author":"Li","year":"2022","journal-title":"Front. Public Health"},{"issue":"8","key":"10.1016\/j.physbeh.2025.115149_bib0025","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2023.28798","article-title":"Lifestyle factors in the association of shift work and depression and anxiety","volume":"6","author":"Xu","year":"2023","journal-title":"JAMA Netw. Open"},{"issue":"3","key":"10.1016\/j.physbeh.2025.115149_bib0026","doi-asserted-by":"crossref","DOI":"10.1111\/jsr.12872","article-title":"Exploring the associations between shift work disorder, depression, anxiety and sick leave taken amongst nurses","volume":"29","author":"Booker","year":"2020","journal-title":"J. Sleep Res."},{"issue":"1","key":"10.1016\/j.physbeh.2025.115149_bib0027","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2018-023247","article-title":"Effect of work schedule on prospective antidepressant prescriptions in Sweden: a 2-year sex-stratified analysis using national drug registry data","volume":"9","author":"Hall","year":"2019","journal-title":"BMJ Open"},{"issue":"5","key":"10.1016\/j.physbeh.2025.115149_bib0028","doi-asserted-by":"crossref","first-page":"1535","DOI":"10.1046\/j.1460-9568.1999.00575.x","article-title":"Anatomical and functional demonstration of a multisynaptic suprachiasmatic nucleus adrenal (cortex) pathway","volume":"11","author":"Buijs","year":"1999","journal-title":"Eur. J. Neurosci."},{"issue":"39","key":"10.1016\/j.physbeh.2025.115149_bib0029","doi-asserted-by":"crossref","first-page":"15172","DOI":"10.1073\/pnas.0806717105","article-title":"Physiological significance of a peripheral tissue circadian clock","volume":"105","author":"Lamia","year":"2008","journal-title":"Proc. Natl. Acad. Sci."},{"issue":"11","key":"10.1016\/j.physbeh.2025.115149_bib0030","doi-asserted-by":"crossref","first-page":"e377","DOI":"10.1371\/journal.pbio.0020377","article-title":"BMAL1 and CLOCK, two essential components of the circadian clock, are involved in glucose homeostasis","volume":"2","author":"Rudic","year":"2004","journal-title":"PLoS Biol."},{"issue":"5","key":"10.1016\/j.physbeh.2025.115149_bib0031","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1016\/j.cub.2013.01.048","article-title":"Circadian disruption leads to insulin resistance and obesity","volume":"23","author":"Shi","year":"2013","journal-title":"Current Biol."},{"key":"10.1016\/j.physbeh.2025.115149_bib0032","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijnurstu.2023.104490","article-title":"Shift work domains and their interactions with empty calorie food\/beverage consumption: a 14-day intensive longitudinal study","volume":"141","author":"Lin","year":"2023","journal-title":"Int. J. Nurs. Stud."},{"issue":"4","key":"10.1016\/j.physbeh.2025.115149_bib0033","doi-asserted-by":"crossref","first-page":"627","DOI":"10.3390\/medicina60040627","article-title":"The effect of shift working on dietary patterns of healthcare practitioners during the COVID-19 pandemic: a cross-sectional study","volume":"60","author":"Migdanis","year":"2024","journal-title":"Medicina (B Aires)"},{"issue":"6","key":"10.1016\/j.physbeh.2025.115149_bib0034","doi-asserted-by":"crossref","first-page":"2242","DOI":"10.4103\/jfmpc.jfmpc_1368_23","article-title":"Effect of shift work on dietary habits and occupational stress among nurses in a tertiary care centre: an observational study","volume":"13","author":"Shrivastava","year":"2024","journal-title":"J. Family Med. Prim. Care"},{"issue":"5","key":"10.1016\/j.physbeh.2025.115149_bib0035","doi-asserted-by":"crossref","first-page":"699","DOI":"10.3897\/folmed.66.e132829","article-title":"Investigating the types of eating behavior among shift workers in the machine-building industry","volume":"66","author":"Todorova","year":"2024","journal-title":"Folia Med. (Plovdiv)"},{"issue":"7","key":"10.1016\/j.physbeh.2025.115149_bib0036","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0101702","article-title":"Effect of high sugar intake on glucose transporter and weight regulating hormones in mice and humans","volume":"9","author":"Ritze","year":"2014","journal-title":"PLoS One"},{"issue":"10","key":"10.1016\/j.physbeh.2025.115149_bib0037","doi-asserted-by":"crossref","first-page":"995","DOI":"10.3390\/antiox9100995","article-title":"Western diet causes obesity-induced nonalcoholic fatty liver disease development by differentially compromising the autophagic response","volume":"9","author":"Simoes","year":"2020","journal-title":"Antioxidants"},{"issue":"10","key":"10.1016\/j.physbeh.2025.115149_bib0038","doi-asserted-by":"crossref","first-page":"1034","DOI":"10.1038\/s42255-020-0261-2","article-title":"Fructose stimulated de novo lipogenesis is promoted by inflammation","volume":"2","author":"Todoric","year":"2020","journal-title":"Nat. Metab."},{"issue":"1","key":"10.1016\/j.physbeh.2025.115149_bib0039","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1167\/iovs.66.1.12","article-title":"Chronic jet lag disrupts circadian rhythms and induces hyperproliferation in murine lacrimal glands via ROS accumulation","volume":"66","author":"Huang","year":"2025","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.physbeh.2025.115149_bib0040","doi-asserted-by":"crossref","DOI":"10.3389\/fvets.2021.621188","article-title":"Chronic exposure to continuous brightness or darkness modulates immune responses and ameliorates the antioxidant enzyme system in male rats","volume":"8","author":"Moustafa","year":"2021","journal-title":"Front. Vet. Sci."},{"key":"10.1016\/j.physbeh.2025.115149_bib0041","doi-asserted-by":"crossref","DOI":"10.3389\/fphys.2023.1225134","article-title":"Chronic jet lag reduces motivation and affects other mood-related behaviors in male mice","volume":"14","author":"Acosta","year":"2023","journal-title":"Front. Physiol."},{"issue":"1","key":"10.1016\/j.physbeh.2025.115149_bib0042","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1038\/s44323-025-00032-6","article-title":"Chronic circadian disruption alters cardiac function and glucose regulation in mice","volume":"2","author":"Gearey","year":"2025","journal-title":"npj Biol. Timing Sleep"},{"issue":"2","key":"10.1016\/j.physbeh.2025.115149_bib0043","doi-asserted-by":"crossref","first-page":"E276","DOI":"10.1152\/ajpendo.00529.2019","article-title":"Sugar causes obesity and metabolic syndrome in mice independently of sweet taste","volume":"319","author":"Andres-Hernando","year":"2020","journal-title":"Am. J. Physiol.-Endocrinol. Metab."},{"issue":"1","key":"10.1016\/j.physbeh.2025.115149_bib0044","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1038\/s44324-024-00043-0","article-title":"The effect of high-sugar feeding on rodent metabolic phenotype: a systematic review and meta-analysis","volume":"2","author":"Fisher","year":"2024","journal-title":"npj Metab. Health Dis."},{"issue":"5","key":"10.1016\/j.physbeh.2025.115149_bib0045","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1007\/s11011-024-01352-5","article-title":"High sugar consumption for seven days in adult mice increased blood glucose variability, induced an anxiolytic effect and triggered oxidative stress in cerebral cortex","volume":"39","author":"Lahouel","year":"2024","journal-title":"Metab. Brain Dis."},{"key":"10.1016\/j.physbeh.2025.115149_bib0046","doi-asserted-by":"crossref","DOI":"10.3389\/fnut.2023.1171806","article-title":"The impact of high-glucose or high-fat diets on the metabolomic profiling of mice","volume":"10","author":"Xie","year":"2023","journal-title":"Front. Nutr."},{"issue":"4","key":"10.1016\/j.physbeh.2025.115149_bib0047","doi-asserted-by":"crossref","first-page":"959","DOI":"10.3390\/antiox12040959","article-title":"Impaired melatonin secretion, oxidative stress and metabolic syndrome in night shift work","volume":"12","author":"Hohor","year":"2023","journal-title":"Antioxidants"},{"key":"10.1016\/j.physbeh.2025.115149_bib0048","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.neubiorev.2019.05.021","article-title":"The impact of sugar consumption on stress driven, emotional and addictive behaviors","volume":"103","author":"Jacques","year":"2019","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.physbeh.2025.115149_bib0049","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2022.988481","article-title":"Excessive intake of sugar: an accomplice of inflammation","volume":"13","author":"Ma","year":"2022","journal-title":"Front. Immunol."},{"issue":"02","key":"10.1016\/j.physbeh.2025.115149_bib0050","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1055\/s-0043-1770798","article-title":"Shift work and metabolic syndrome updates: a systematic review","volume":"16","author":"Schettini","year":"2023","journal-title":"Sleep Sci."},{"issue":"2","key":"10.1016\/j.physbeh.2025.115149_bib0051","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1089\/neu.2011.1942","article-title":"Lithium ameliorates neurodegeneration, suppresses neuroinflammation, and improves behavioral performance in a mouse model of traumatic brain injury","volume":"29","author":"Yu","year":"2012","journal-title":"J. Neurotrauma"},{"issue":"2","key":"10.1016\/j.physbeh.2025.115149_bib0052","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1038\/nprot.2007.44","article-title":"The use of the elevated plus maze as an assay of anxiety-related behavior in rodents","volume":"2","author":"Walf","year":"2007","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.physbeh.2025.115149_bib0053","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.ab.2013.10.001","article-title":"Digital image analysis approach for lipid droplet size quantitation of oil Red O-stained cultured cells","volume":"445","author":"Deutsch","year":"2014","journal-title":"Anal. Biochem."},{"issue":"1\u20132","key":"10.1016\/j.physbeh.2025.115149_bib0054","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","article-title":"A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding","volume":"72","author":"Bradford","year":"1976","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.physbeh.2025.115149_bib0055","series-title":"In Methods of Enzymatic Analysis","first-page":"673","author":"Catalase","year":"1974"},{"issue":"3","key":"10.1016\/j.physbeh.2025.115149_bib0056","first-page":"201","article-title":"A modified spectrophotometric assay of superoxide dismutase using nitrite formation by superoxide radicals","volume":"37","author":"Das","year":"2000","journal-title":"Indian J. Biochem. Biophys."},{"issue":"2","key":"10.1016\/j.physbeh.2025.115149_bib0057","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/j.advnut.2023.01.006","article-title":"Dietary patterns under the influence of rotational shift work schedules: a systematic review and meta-analysis","volume":"14","author":"Clark","year":"2023","journal-title":"Adv. Nutr."},{"issue":"4","key":"10.1016\/j.physbeh.2025.115149_bib0058","doi-asserted-by":"crossref","first-page":"419","DOI":"10.2486\/indhealth.2018-0147","article-title":"The factors influencing the eating behaviour of shiftworkers: what, when, where and why","volume":"57","author":"Gupta","year":"2019","journal-title":"Ind. Health"},{"issue":"1","key":"10.1016\/j.physbeh.2025.115149_bib0059","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1186\/s13098-015-0041-4","article-title":"Shift work and its association with metabolic disorders","volume":"7","author":"Brum","year":"2015","journal-title":"Diabetol. Metab. Syndr."},{"issue":"6","key":"10.1016\/j.physbeh.2025.115149_bib0060","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1111\/jsr.12554","article-title":"Night-shift work is associated with poorer glycaemic control in patients with type 2 diabetes","volume":"26","author":"Manodpitipong","year":"2017","journal-title":"J. Sleep Res."},{"issue":"2","key":"10.1016\/j.physbeh.2025.115149_bib0061","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1093\/occmed\/kqr001","article-title":"Shift work and chronic disease: the epidemiological evidence","volume":"61","author":"Wang","year":"2011","journal-title":"Occup. Med. (Chic. Ill)"},{"issue":"3","key":"10.1016\/j.physbeh.2025.115149_bib0062","doi-asserted-by":"crossref","DOI":"10.1111\/apha.14005","article-title":"Sweet treats before sleep disrupt the clock system and increase metabolic risk markers in healthy rats","volume":"239","author":"Soliz-Rueda","year":"2023","journal-title":"Acta Physiol."},{"key":"10.1016\/j.physbeh.2025.115149_bib0063","doi-asserted-by":"crossref","DOI":"10.1016\/j.physbeh.2024.114780","article-title":"Time-restricted feeding does not improve daily rhythms in locomotion and drinking disrupted by artificial light at night","volume":"290","author":"Rumanova","year":"2025","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.physbeh.2025.115149_bib0064","doi-asserted-by":"crossref","DOI":"10.1016\/j.mce.2025.112559","article-title":"Interactive effects of light at night and high fructose intake on the central circadian clock and endocrine outputs in rats","author":"Zeman","year":"2025","journal-title":"Mol. Cell Endocrinol."},{"issue":"4","key":"10.1016\/j.physbeh.2025.115149_bib0065","first-page":"698","article-title":"Shiftworking, nutrition and obesity: implications for workforce health-a systematic review","volume":"22","author":"Amani","year":"2013","journal-title":"Asia Pac. J. Clin. Nutr."},{"issue":"6","key":"10.1016\/j.physbeh.2025.115149_bib0066","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1007\/s00420-021-01662-6","article-title":"The mediating role of lifestyle in the relationship between shift work, obesity and diabetes","volume":"94","author":"Hulsegge","year":"2021","journal-title":"Int. Arch. Occup. Environ. Health"},{"issue":"2","key":"10.1016\/j.physbeh.2025.115149_bib0067","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1017\/S095442241500013X","article-title":"Dietary and lifestyle habits and the associated health risks in shift workers","volume":"28","author":"Nea","year":"2015","journal-title":"Nutr. Res. Rev."},{"issue":"1","key":"10.1016\/j.physbeh.2025.115149_bib0068","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-024-72450-8","article-title":"Sucrose binge-eating and increased anxiety-like behavior in Sprague\u2013Dawley rats exposed to repeated LPS administration followed by chronic mild unpredictable stress","volume":"14","author":"Aran\u0111elovi\u0107","year":"2024","journal-title":"Sci. Rep."},{"issue":"5","key":"10.1016\/j.physbeh.2025.115149_bib0069","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0176554","article-title":"Increased anxiety-like behavior is associated with the metabolic syndrome in non-stressed rats","volume":"12","author":"Rebolledo-Solleiro","year":"2017","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.physbeh.2025.115149_bib0070","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.neubiorev.2007.04.019","article-title":"Evidence for sugar addiction: behavioral and neurochemical effects of intermittent, excessive sugar intake","volume":"32","author":"Avena","year":"2008","journal-title":"Neurosci. Biobehav. Rev."},{"issue":"2","key":"10.1016\/j.physbeh.2025.115149_bib0071","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.physbeh.2012.06.017","article-title":"Effects of CB1 and CRF1 receptor antagonists on binge-like eating in rats with limited access to a sweet fat diet: lack of withdrawal-like responses","volume":"107","author":"Parylak","year":"2012","journal-title":"Physiol. Behav."},{"issue":"2","key":"10.1016\/j.physbeh.2025.115149_bib0072","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1007\/s41782-023-00246-3","article-title":"Implication of sleep and food intake pattern on the depressive status of the female shift workers engaged in two-shift system","volume":"7","author":"Majumdar","year":"2023","journal-title":"Sleep. Vigil."},{"issue":"3","key":"10.1016\/j.physbeh.2025.115149_bib0073","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1016\/j.psc.2009.05.004","article-title":"The neurobiology of anxiety disorders: brain imaging, genetics, and psychoneuroendocrinology","volume":"32","author":"Martin","year":"2009","journal-title":"Psychiatr. Clin. North Am."},{"key":"10.1016\/j.physbeh.2025.115149_bib0074","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jad.2017.12.001","article-title":"Neurobiology of the dorsolateral prefrontal cortex in GAD: aberrant neurometabolic correlation to hippocampus and relationship to anxiety sensitivity and IQ","volume":"229","author":"Coplan","year":"2018","journal-title":"J. Affect. Disord."},{"issue":"1","key":"10.1016\/j.physbeh.2025.115149_bib0075","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1093\/nutrit\/nuw046","article-title":"What is the appropriate upper limit for added sugars consumption?","volume":"75","author":"Rippe","year":"2017","journal-title":"Nutr. Rev."},{"issue":"11","key":"10.1016\/j.physbeh.2025.115149_bib0076","doi-asserted-by":"crossref","first-page":"712","DOI":"10.3390\/nu8110712","article-title":"Shift in food intake and changes in metabolic regulation and gene expression during simulated night-shift work: a rat model","volume":"8","author":"Marti","year":"2016","journal-title":"Nutrients"},{"issue":"3","key":"10.1016\/j.physbeh.2025.115149_bib0077","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1210\/en.2009-0864","article-title":"Food intake during the normal activity phase prevents obesity and circadian desynchrony in a rat model of night work","volume":"151","author":"Salgado-Delgado","year":"2010","journal-title":"Endocrinology"},{"issue":"7","key":"10.1016\/j.physbeh.2025.115149_bib0078","doi-asserted-by":"crossref","first-page":"1948","DOI":"10.1053\/j.gastro.2020.01.050","article-title":"Circadian rhythms in the pathogenesis and treatment of fatty liver disease","volume":"158","author":"Saran","year":"2020","journal-title":"Gastroenterology"},{"issue":"6","key":"10.1016\/j.physbeh.2025.115149_bib0079","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1159\/000446514","article-title":"Short exposure to a high-sucrose diet and the first \u2018hit'of nonalcoholic fatty liver disease in mice","volume":"201","author":"Fernandes-Lima","year":"2016","journal-title":"Cells Tissues Organs"},{"issue":"suppl 2","key":"10.1016\/j.physbeh.2025.115149_bib0080","article-title":"Long-term hepatic damage in high-fructose-fed C57BL\/6 mice: hepatic fibrogenesis, endoplasmic reticulum stress markers, and fibrosis","volume":"95","author":"Oliveira-Cordeiro","year":"2023","journal-title":"An. Acad. Bras. Ci\u00eanc."},{"issue":"5","key":"10.1016\/j.physbeh.2025.115149_bib0081","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1016\/j.jhep.2009.05.033","article-title":"Soft drink consumption is associated with fatty liver disease independent of metabolic syndrome","volume":"51","author":"Abid","year":"2009","journal-title":"J. Hepatol."},{"issue":"5","key":"10.1016\/j.physbeh.2025.115149_bib0082","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1038\/nrgastro.2010.41","article-title":"The role of fructose in the pathogenesis of NAFLD and the metabolic syndrome","volume":"7","author":"Lim","year":"2010","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"issue":"22","key":"10.1016\/j.physbeh.2025.115149_bib0083","doi-asserted-by":"crossref","DOI":"10.3390\/ijms232214275","article-title":"The influence of circadian rhythm on the activity of oxidative stress enzymes","volume":"23","author":"Budkowska","year":"2022","journal-title":"Int. J. Mol. Sci."},{"issue":"4","key":"10.1016\/j.physbeh.2025.115149_bib0084","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1016\/j.cegh.2019.01.002","article-title":"Association between metabolic risk, oxidative stress and rotating shift work in a tertiary health care facility","volume":"7","author":"Gowda","year":"2019","journal-title":"Clin. Epidemiol. Glob. Health"},{"issue":"8","key":"10.1016\/j.physbeh.2025.115149_bib0085","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1007\/s00420-012-0828-7","article-title":"Relationship between intensity of night shift work and antioxidant status in blood of nurses","volume":"86","author":"Gromadzi\u0144ska","year":"2013","journal-title":"Int. Arch. Occup. Environ. Health"},{"issue":"1","key":"10.1016\/j.physbeh.2025.115149_bib0086","doi-asserted-by":"crossref","first-page":"4455","DOI":"10.1038\/s41598-019-40989-6","article-title":"Night workers have lower levels of antioxidant defenses and higher levels of oxidative stress damage when compared to day workers","volume":"9","author":"Teixeira","year":"2019","journal-title":"Sci. Rep."},{"key":"10.1016\/j.physbeh.2025.115149_bib0087","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.clnesp.2020.02.018","article-title":"Assessment and comparison of the antioxidant defense system in patients with type 2 diabetes, diabetic nephropathy and healthy people: a case\u2013control study","volume":"37","author":"Lotfi","year":"2020","journal-title":"Clin. Nutr. ESPEN"},{"issue":"9","key":"10.1016\/j.physbeh.2025.115149_bib0088","doi-asserted-by":"crossref","first-page":"2071","DOI":"10.3390\/nu15092071","article-title":"Inverse correlation of superoxide dismutase and catalase with type 2 diabetes among rural Thais","volume":"15","author":"Promyos","year":"2023","journal-title":"Nutrients"},{"issue":"8","key":"10.1016\/j.physbeh.2025.115149_bib0089","doi-asserted-by":"crossref","first-page":"1483","DOI":"10.1007\/s00125-017-4317-0","article-title":"Glucose metabolism during rotational shift-work in healthcare workers","volume":"60","author":"Sharma","year":"2017","journal-title":"Diabetologia"},{"issue":"03","key":"10.1016\/j.physbeh.2025.115149_bib0090","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1055\/s-0039-1697211","article-title":"The risk of night shift workers to the glucose blood levels, saliva, and dental caries","volume":"13","author":"Roestamadji","year":"2019","journal-title":"Eur. J. Dent."},{"issue":"5","key":"10.1016\/j.physbeh.2025.115149_bib0091","doi-asserted-by":"crossref","first-page":"1710","DOI":"10.4103\/jfmpc.jfmpc_375_21","article-title":"Effect of night shift on development of metabolic syndrome among health care workers","volume":"11","author":"Bahinipati","year":"2022","journal-title":"J. Family Med. Prim. Care"},{"issue":"6","key":"10.1016\/j.physbeh.2025.115149_bib0092","doi-asserted-by":"crossref","first-page":"G932","DOI":"10.1152\/ajpgi.00020.2018","article-title":"A rotating light cycle promotes weight gain and hepatic lipid storage in mice","volume":"315","author":"Christie","year":"2018","journal-title":"Am. J. physiol.-Gastrointest. Liver Physiol."},{"key":"10.1016\/j.physbeh.2025.115149_bib0093","doi-asserted-by":"crossref","DOI":"10.1016\/j.physbeh.2022.113772","article-title":"Circadian rhythm disorders elevate macrophages cytokines release and promote multiple tissues\/organs dysfunction in mice","volume":"249","author":"Sun","year":"2022","journal-title":"Physiol. Behav."},{"issue":"8","key":"10.1016\/j.physbeh.2025.115149_bib0094","first-page":"4282","article-title":"Nonalcoholic fatty liver disease in CLOCK mutant mice","volume":"130","author":"Pan","year":"2020","journal-title":"J. Clin. Invest."},{"issue":"1","key":"10.1016\/j.physbeh.2025.115149_bib0095","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-024-68378-8","article-title":"Investigating the relationship between shift work schedule and blood and metabolic parameters: a 10-years retrospective cohort study","volume":"14","author":"Soltanzadeh","year":"2024","journal-title":"Sci. Rep."},{"issue":"1","key":"10.1016\/j.physbeh.2025.115149_bib0096","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1080\/07420528.2019.1684936","article-title":"The effects of exposure to night shift work on liver function: a cross-sectional study with emphasis of alkaline phosphatase enzyme","volume":"37","author":"Khosravipour","year":"2020","journal-title":"Chronobiol. Int."},{"key":"10.1016\/j.physbeh.2025.115149_bib0097","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2023.1237467","article-title":"Peripheral blood lipid and liver and kidney function test results in long-term night shift nurses: a cross-sectional study in South China","volume":"14","author":"Zhao","year":"2023","journal-title":"Front. Endocrinol. (Lausanne)"},{"issue":"3","key":"10.1016\/j.physbeh.2025.115149_bib0098","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/0002-9343(92)90230-9","article-title":"Increased triglyceride levels in shift workers","volume":"93","author":"Romon","year":"1992","journal-title":"Am. J. Med."}],"container-title":["Physiology & Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0031938425003506?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0031938425003506?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T07:34:32Z","timestamp":1773819272000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0031938425003506"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":98,"alternative-id":["S0031938425003506"],"URL":"https:\/\/doi.org\/10.1016\/j.physbeh.2025.115149","relation":{},"ISSN":["0031-9384"],"issn-type":[{"value":"0031-9384","type":"print"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Impact of high sugar intake on neurobehavioral, oxidative, and hepatic integrity in mice exposed to simulated chronic jetlag\/shiftwork","name":"articletitle","label":"Article Title"},{"value":"Physiology & Behavior","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.physbeh.2025.115149","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"115149"}}