{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T18:08:52Z","timestamp":1788977332860,"version":"build-2803163510"},"reference-count":44,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T00:00:00Z","timestamp":1785283200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001871","name":"Fundacao para a Ciencia e a Tecnologia","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Physiology &amp; Behavior"],"published-print":{"date-parts":[[2026,11]]},"DOI":"10.1016\/j.physbeh.2026.115457","type":"journal-article","created":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T07:09:14Z","timestamp":1785481754000},"page":"115457","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Salivary protein changes over time in response to food smell - methodological implications"],"prefix":"10.1016","volume":"316","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9866-1015","authenticated-orcid":false,"given":"Carla","family":"Sim\u00f5es","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paula Midori","family":"Castelo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Isabel","family":"Costa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9370-1337","authenticated-orcid":false,"given":"Elsa","family":"Lamy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.physbeh.2026.115457_bib0001","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/j.appet.2007.10.006","article-title":"Anticipatory physiological regulation in feeding biology: cephalic phase responses","author":"Power","year":"2008","journal-title":"Appetite"},{"issue":"11","key":"10.1016\/j.physbeh.2026.115457_bib0002","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1111\/j.1753-4887.2010.00334.x","article-title":"Cephalic phase responses and appetite","volume":"68","author":"Smeets","year":"2010","journal-title":"Nutr. Rev."},{"key":"10.1016\/j.physbeh.2026.115457_bib0003","article-title":"Influence of sensory properties in moderating eating behaviors and food intake","volume":"9","author":"Forde","year":"2022"},{"issue":"2","key":"10.1016\/j.physbeh.2026.115457_bib0004","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1006\/appe.1999.0278","article-title":"Nutritional implications of the cephalic-phase salivary response","volume":"34","author":"Mattes","year":"2000","journal-title":"Appetite"},{"key":"10.1016\/j.physbeh.2026.115457_bib0005","unstructured":"Pavlov, I. P. (1902). The work of the digestive glands (Thompson W H, Tran.). Charles Griffin."},{"key":"10.1016\/j.physbeh.2026.115457_bib0006","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1097\/00006842-199603000-00011","article-title":"Differences in salivation to repeated food cues in obese and nonobese women","volume":"58","author":"Epstein","year":"1996","journal-title":"Psychosom. Med."},{"issue":"11","key":"10.1016\/j.physbeh.2026.115457_bib0007","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0165449","article-title":"Consumption simulations induce salivation to food cues","volume":"11","author":"Keesman","year":"2016","journal-title":"PLoS One"},{"issue":"8","key":"10.1016\/j.physbeh.2026.115457_bib0008","first-page":"679","article-title":"Hunger\/craving responses and reactivity to food stimuli during fasting and dieting","volume":"14","author":"Lappalainen","year":"1990","journal-title":"Int. J. Obes."},{"key":"10.1016\/j.physbeh.2026.115457_bib0009","doi-asserted-by":"crossref","DOI":"10.1016\/j.appet.2019.104399","article-title":"Impact of food odors signaling specific taste qualities and macronutrient content on saliva secretion and composition","volume":"143","author":"Morquecho-Campos","year":"2019","journal-title":"Appetite"},{"key":"10.1016\/j.physbeh.2026.115457_bib0010","doi-asserted-by":"crossref","first-page":"1340","DOI":"10.2466\/pms.1968.27.3f.1340","article-title":"Parotid flow stimulated by the sight, feel and odor of lemon","volume":"27","author":"Pangborn","year":"1968","journal-title":"Percept. Mot. Ski."},{"issue":"3","key":"10.1016\/j.physbeh.2026.115457_bib0011","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1111\/j.1745-4603.2011.00290.x","article-title":"Is the mouthwatering sensation a true salivary reflex?","volume":"42","author":"Ilangakoon","year":"2011","journal-title":"J. Texture Stud."},{"issue":"1","key":"10.1016\/j.physbeh.2026.115457_bib0012","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1086\/674664","article-title":"Smellizing cookies and salivating: a focus on olfactory imagery","volume":"41","author":"Krishna","year":"2014","journal-title":"J. Consum. Res."},{"key":"10.1016\/j.physbeh.2026.115457_bib0013","doi-asserted-by":"crossref","DOI":"10.1016\/j.physbeh.2020.113116","article-title":"A stepwise approach investigating salivary responses upon multisensory food cues","volume":"226","author":"Morquecho-Campos","year":"2020","journal-title":"Physiol. Behav."},{"issue":"1","key":"10.1016\/j.physbeh.2026.115457_bib0014","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1113\/expphysiol.1992.sp003578","article-title":"An olfactory-submandibular salivary reflex in humans","volume":"77","author":"Lee","year":"1992","journal-title":"Exp. Physiol."},{"issue":"36","key":"10.1016\/j.physbeh.2026.115457_bib0015","article-title":"Olfactory memory networks: from emotional learning to social behaviors","volume":"9","author":"Sullivan","year":"2015","journal-title":"Front. Behav. Neurosci."},{"key":"10.1016\/j.physbeh.2026.115457_bib0016","doi-asserted-by":"crossref","DOI":"10.3389\/fphys.2019.01151","article-title":"Sense of smell as the central driver of Pavlovian appetite behavior in mammals","volume":"10","author":"Fine","year":"2019","journal-title":"Front. Physiol."},{"issue":"4","key":"10.1016\/j.physbeh.2026.115457_bib0017","doi-asserted-by":"crossref","DOI":"10.3390\/nu12041002","article-title":"Changes in salivary proteome in response to bread odour","volume":"12","author":"Carreira","year":"2020","journal-title":"Nutrients"},{"key":"10.1016\/j.physbeh.2026.115457_bib0018","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.physbeh.2017.02.042","article-title":"Impact of ambient odors on food intake, saliva production and appetite ratings","volume":"174","author":"Proserpio","year":"2017","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.physbeh.2026.115457_bib0019","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodqual.2020.104167","article-title":"The appeal of virtual chocolate: a systematic comparison of psychological and physiological food cue responses to virtual and real food","volume":"90","author":"van der Waal","year":"2021","journal-title":"Food Qual. Prefer."},{"key":"10.1016\/j.physbeh.2026.115457_bib0020","first-page":"209","article-title":"Start looking at saliva: effect of visualization of food images on salivary proteome","author":"Marques","year":"2025","journal-title":"Food Res. Int."},{"key":"10.1016\/j.physbeh.2026.115457_bib0021","first-page":"13","article-title":"Habituation and adaptation to odors in humans","volume":"177","author":"Pellegrino","year":"2017"},{"issue":"1","key":"10.1016\/j.physbeh.2026.115457_bib0022","doi-asserted-by":"crossref","DOI":"10.1186\/s12576-021-00822-0","article-title":"Differences in olfactory habituation between orthonasal and retronasal pathways","volume":"71","author":"Xiao","year":"2021","journal-title":"J. Physiol. Sci."},{"issue":"1","key":"10.1016\/j.physbeh.2026.115457_bib0023","article-title":"Prolonged exposure to food odors suppresses feeding via an olfactory bulb-to-hypothalamus circuit","volume":"16","author":"Liu","year":"2025","journal-title":"Nat. Commun."},{"key":"10.1016\/j.physbeh.2026.115457_bib0024","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.autneu.2006.10.006","article-title":"Regulation of salivary gland function by autonomic nerves","volume":"133","author":"Proctor","year":"2007","journal-title":"Auton. Neurosci.: Basic Clin."},{"key":"10.1016\/j.physbeh.2026.115457_bib0025","first-page":"175","article-title":"From scent to saliva: the saliva-stimulating effect of terpenes in dry mouth","author":"Potocka","year":"2025","journal-title":"Arch. Oral Biol."},{"issue":"4","key":"10.1016\/j.physbeh.2026.115457_bib0026","doi-asserted-by":"crossref","DOI":"10.1007\/s13105-015-0434-8","article-title":"Changes in the salivary protein profile of morbidly obese women either previously subjected to bariatric surgery or not","volume":"71","author":"Lamy","year":"2015","journal-title":"J. Physiol. Biochem."},{"issue":"1","key":"10.1016\/j.physbeh.2026.115457_bib0027","doi-asserted-by":"crossref","DOI":"10.1080\/16546628.2017.1389208","article-title":"Salivary proteome and glucose levels are related with sweet taste sensitivity in young adults","volume":"61","author":"Rodrigues","year":"2017","journal-title":"Food Nutr. Res."},{"issue":"12","key":"10.1016\/j.physbeh.2026.115457_bib0028","doi-asserted-by":"crossref","first-page":"1032","DOI":"10.1002\/elps.1150121207","article-title":"Sodium dodecyl sulphate-polyacrylamide gel electrophoresis of human parotid salivary proteins","volume":"12","author":"Beeley","year":"1991","journal-title":"Electrophoresis"},{"key":"10.1016\/j.physbeh.2026.115457_bib0029","first-page":"225","article-title":"Addition of chocolate milk to diet corresponds to protein concentration changes in human saliva","author":"Crawford","year":"2020","journal-title":"Physiol. Behav."},{"issue":"10","key":"10.1016\/j.physbeh.2026.115457_bib0030","doi-asserted-by":"crossref","first-page":"2811","DOI":"10.1007\/s00405-019-05558-7","article-title":"Influence of olfactory dysfunction on the perception of food","volume":"276","author":"Zang","year":"2019","journal-title":"Eur. Arch. Oto-Rhino-Laryngol."},{"issue":"1","key":"10.1016\/j.physbeh.2026.115457_bib0031","article-title":"Odor habituation can modulate very early olfactory event-related potential","volume":"10","author":"Kim","year":"2020","journal-title":"Sci. Rep."},{"key":"10.1016\/j.physbeh.2026.115457_bib0032","doi-asserted-by":"crossref","unstructured":"Sobel, N., Prabhakaran, V., Zhao, Z., Desmond, J. E., Glover, G. H., Sullivan, E. V, & Gabrieli, J. D. E. (2000). Time course of odorant-induced activation in the human primary olfactory cortex. https:\/\/doi.org\/10.1152\/jn.2000.83.1.537.","DOI":"10.1152\/jn.2000.83.1.537"},{"issue":"2013","key":"10.1016\/j.physbeh.2026.115457_bib0033","article-title":"Secretory immunity with special reference to the oral cavity","volume":"5","author":"Brandtzaeg","year":"2013","journal-title":"J. Oral Microbiol."},{"issue":"1","key":"10.1016\/j.physbeh.2026.115457_bib0034","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1093\/emph\/eoac042","article-title":"Disgusting odors trigger the oral immune system","volume":"11","author":"Anja Juran","year":"2023","journal-title":"Evol. Med. Public Health"},{"key":"10.1016\/j.physbeh.2026.115457_bib0035","series-title":"Proceedings of the Society for Experimental Biology and Medicine","first-page":"59","article-title":"Differential effect of autonomic stimulation on salivary secretion of IgG, IgA and amylase (401 39)","volume":"158","author":"El-Mofty","year":"1978"},{"issue":"Suppl. S700","key":"10.1016\/j.physbeh.2026.115457_bib0036","article-title":"Can the odours modulate salivation? Impact of the nature of the odorant","volume":"214","author":"Neyraud","year":"2015","journal-title":"Congr. Physiol. Integr. Biol. (CPBI) Acta Physiol."},{"issue":"1","key":"10.1016\/j.physbeh.2026.115457_bib0037","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-025-29493-2","article-title":"Investigating the influence of astringent compounds on oral lubrication and the protective role of proline-rich proteins","volume":"16","author":"Ammam","year":"2026","journal-title":"Sci. Rep."},{"issue":"39","key":"10.1016\/j.physbeh.2026.115457_bib0038","doi-asserted-by":"crossref","first-page":"9562","DOI":"10.1021\/jf502721c","article-title":"In vivo interactions between procyanidins and human saliva proteins: effect of repeated exposures to procyanidins solution","volume":"62","author":"Brand\u00e3o","year":"2014","journal-title":"J. Agric. Food Chem."},{"issue":"5","key":"10.1016\/j.physbeh.2026.115457_bib0039","doi-asserted-by":"crossref","first-page":"1631","DOI":"10.1002\/pmic.200500125","article-title":"Proteome analysis of glandular parotid and submandibular-sublingual saliva in comparison to whole human saliva by two-dimensional gel electrophoresis","volume":"6","author":"Walz","year":"2006","journal-title":"Proteomics"},{"key":"10.1016\/j.physbeh.2026.115457_bib0040","doi-asserted-by":"crossref","first-page":"47","DOI":"10.14748\/bmr.v2.211","article-title":"Neural regulation of the protein composition of saliva","volume":"2","author":"Proctor","year":"1993","journal-title":"Biomed. Rev."},{"issue":"7","key":"10.1016\/j.physbeh.2026.115457_bib0041","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1093\/jn\/117.7.1191","article-title":"Cephalic reflexes: their role in digestion and possible roles in absorption and metabolism","volume":"117","author":"Giduck","year":"1987","journal-title":"J. Nutr."},{"issue":"3","key":"10.1016\/j.physbeh.2026.115457_bib0042","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/s21030770","article-title":"Wearable sensors for assessing the role of olfactory training on the autonomic response to olfactory stimulation","volume":"21","author":"Tonacci","year":"2021","journal-title":"Sensors"},{"issue":"1","key":"10.1016\/j.physbeh.2026.115457_bib0043","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1111\/j.1600-0765.1990.tb01202.x","article-title":"The protein composition of gingival crevicular fluid sampled from male adolescents with no destructive periodontitis: baseline data of a longitudinal study","volume":"25","author":"Curtis","year":"1990","journal-title":"J. Periodontal Res."},{"key":"10.1016\/j.physbeh.2026.115457_fur1","doi-asserted-by":"crossref","unstructured":"P. Morquecho-Campos, K. de Graaf, S. Boesveldt, Smelling our appetite? The influence of food odors on congruent appetite, food preferences and intake, Food Qual. Prefer. 85 (2020), 10.1016\/j.foodqual.2020.103959.","DOI":"10.1016\/j.foodqual.2020.103959"}],"container-title":["Physiology &amp; Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0031938426002404?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0031938426002404?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T17:37:06Z","timestamp":1788975426000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0031938426002404"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,11]]},"references-count":44,"alternative-id":["S0031938426002404"],"URL":"https:\/\/doi.org\/10.1016\/j.physbeh.2026.115457","relation":{},"ISSN":["0031-9384"],"issn-type":[{"value":"0031-9384","type":"print"}],"subject":[],"published":{"date-parts":[[2026,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Salivary protein changes over time in response to food smell - methodological implications","name":"articletitle","label":"Article Title"},{"value":"Physiology & Behavior","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.physbeh.2026.115457","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Author(s). Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"115457"}}