{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T21:49:11Z","timestamp":1791668951706,"version":"4.3.4"},"reference-count":65,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100004410","name":"T\u00fcrkiye Bilimsel ve Teknolojik Ara\u015ft\u0131rma Kurumu","doi-asserted-by":"publisher","award":["122K010"],"award-info":[{"award-number":["122K010"]}],"id":[{"id":"10.13039\/501100004410","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Physiology &amp; Behavior"],"published-print":{"date-parts":[[2026,12]]},"DOI":"10.1016\/j.physbeh.2026.115503","type":"journal-article","created":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T00:22:50Z","timestamp":1789086170000},"page":"115503","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["PACAP neurons of the ventral dentate gyrus are not involved in fear acquisition"],"prefix":"10.1016","volume":"317","author":[{"given":"Osman","family":"Kamal\u0131","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6668-8085","authenticated-orcid":false,"given":"Hacer Beg\u00fcm","family":"Saka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3390-9352","authenticated-orcid":false,"given":"Fuat","family":"Balc\u0131","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5128-3106","authenticated-orcid":false,"given":"Ersin","family":"Yavas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.physbeh.2026.115503_bib0001","doi-asserted-by":"crossref","first-page":"231","DOI":"10.31887\/DCNS.2002.4.3\/tsteimer","article-title":"The biology of fear- and anxiety-related behaviors","volume":"4","author":"Steimer","year":"2002","journal-title":"Dialogues. Clin. Neurosci."},{"issue":"1","key":"10.1016\/j.physbeh.2026.115503_bib0002","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1146\/annurev.ne.15.030192.002033","article-title":"The role of the amygdala in fear and anxiety","volume":"15","author":"Davis","year":"1992","journal-title":"Annu. Rev. Neurosci."},{"issue":"1","key":"10.1016\/j.physbeh.2026.115503_bib0003","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1146\/annurev.ps.44.020193.001533","article-title":"Mammalian brain substrates of aversive classical conditioning","volume":"44","author":"Lavond","year":"1993","journal-title":"Annu. Rev. Psychol."},{"issue":"1","key":"10.1016\/j.physbeh.2026.115503_bib0004","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1146\/annurev.neuro.23.1.155","article-title":"Emotion circuits in the brain","volume":"23","author":"LeDoux","year":"2000","journal-title":"Annu. Rev. Neurosci."},{"issue":"6","key":"10.1016\/j.physbeh.2026.115503_bib0005","doi-asserted-by":"crossref","first-page":"1365","DOI":"10.1037\/0735-7044.110.6.1365","article-title":"N-methyl-D-aspartate receptors in the basolateral amygdala are required for both acquisition and expression of conditional fear in rats","volume":"110","author":"Maren","year":"1996","journal-title":"Behav. Neurosci."},{"issue":"2","key":"10.1016\/j.physbeh.2026.115503_bib0006","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1017\/S0140525X0000491X","article-title":"A perceptual-defensive-recuperative model of fear and pain","volume":"3","author":"Bolles","year":"1980","journal-title":"Behav. Brain Sci."},{"issue":"4","key":"10.1016\/j.physbeh.2026.115503_bib0007","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1111\/j.1460-9568.2010.07101.x","article-title":"Neuronal circuits of fear extinction","volume":"31","author":"Herry","year":"2010","journal-title":"Eur. J. Neurosci."},{"issue":"2","key":"10.1016\/j.physbeh.2026.115503_bib0008","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1037\/0033-295X.107.2.289","article-title":"Time, rate, and conditioning","volume":"107","author":"Gallistel","year":"2000","journal-title":"Psychol. Rev."},{"key":"10.1016\/j.physbeh.2026.115503_bib0009","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/j.neubiorev.2017.02.026","article-title":"Don\u2019t fear \u2018fear conditioning\u2019: methodological considerations for the design and analysis of studies on human fear acquisition, extinction, and return of fear","volume":"77","author":"Lonsdorf","year":"2017","journal-title":"Neurosci. Biobehav. Rev."},{"issue":"2","key":"10.1016\/j.physbeh.2026.115503_bib0010","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1037\/0735-7044.106.2.274","article-title":"Differential contribution of amygdala and hippocampus to cued and contextual fear conditioning","volume":"106","author":"Phillips","year":"1992","journal-title":"Behav. Neurosci."},{"key":"10.1016\/j.physbeh.2026.115503_bib0011","doi-asserted-by":"crossref","DOI":"10.1016\/j.psyneuen.2022.105912","article-title":"Longitudinal assessment of amygdala activity in mice susceptible to trauma","volume":"145","author":"Dirven","year":"2022","journal-title":"Psychoneuroendocrinology"},{"issue":"3","key":"10.1016\/j.physbeh.2026.115503_bib0012","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1038\/s41583-019-0260-z","article-title":"Dentate gyrus circuits for encoding, retrieval and discrimination of episodic memories","volume":"21","author":"Hainmueller","year":"2020","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.physbeh.2026.115503_bib0013","doi-asserted-by":"crossref","DOI":"10.3389\/fnbeh.2014.00147","article-title":"Local and regional heterogeneity underlying hippocampal modulation of cognition and mood","volume":"8","author":"Tannenholz","year":"2014","journal-title":"Front. Behav. Neurosci."},{"issue":"1","key":"10.1016\/j.physbeh.2026.115503_bib0014","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1111\/j.1749-6632.2000.tb06738.x","article-title":"Reciprocal connections between the amygdala and the hippocampal formation, perirhinal cortex, and postrhinal cortex in rat: a review","volume":"911","author":"Pitk\u00e4nen","year":"2000","journal-title":"Ann. N. Y. Acad. Sci."},{"issue":"5","key":"10.1016\/j.physbeh.2026.115503_bib0015","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1016\/j.neuron.2012.12.038","article-title":"Differential control of learning and anxiety along the dorsoventral axis of the dentate gyrus","volume":"77","author":"Kheirbek","year":"2013","journal-title":"Neuron"},{"issue":"1","key":"10.1016\/j.physbeh.2026.115503_bib0016","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1007\/s002210100746","article-title":"The ventral hippocampus and fear conditioning in rats","volume":"139","author":"Bast","year":"2001","journal-title":"Exp. Brain Res."},{"issue":"1","key":"10.1016\/j.physbeh.2026.115503_bib0017","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1037\/0735-7044.118.1.97","article-title":"Hippocampus and pavlovian fear conditioning in rats: muscimol infusions into the ventral, but not dorsal, Hippocampus impair the acquisition of conditional freezing to an auditory conditional stimulus","volume":"118","author":"Maren","year":"2004","journal-title":"Behav. Neurosci."},{"issue":"52","key":"10.1016\/j.physbeh.2026.115503_bib0018","doi-asserted-by":"crossref","first-page":"26970","DOI":"10.1073\/pnas.1910481116","article-title":"Ventral hippocampus interacts with prelimbic cortex during inhibition of threat response via learned safety in both mice and humans","volume":"116","author":"Meyer","year":"2019","journal-title":"Proc. Natl. Acad. Sci."},{"issue":"1\u20132","key":"10.1016\/j.physbeh.2026.115503_bib0019","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/S0166-4328(02)00268-1","article-title":"Ventral hippocampal lesions affect anxiety but not spatial learning","volume":"139","author":"Bannerman","year":"2003","journal-title":"Behav. Brain Res."},{"issue":"16","key":"10.1016\/j.physbeh.2026.115503_bib0020","doi-asserted-by":"crossref","first-page":"10825","DOI":"10.1073\/pnas.152112399","article-title":"Reduced fear expression after lesions of the ventral hippocampus","volume":"99","author":"Kjelstrup","year":"2002","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"issue":"5","key":"10.1016\/j.physbeh.2026.115503_bib0021","doi-asserted-by":"crossref","DOI":"10.1111\/acel.13600","article-title":"Alzheimer-like tau accumulation in dentate gyrus mossy cells induces spatial cognitive deficits by disrupting multiple memory-related signaling and inhibiting local neural circuit","volume":"21","author":"Li","year":"2022","journal-title":"Aging Cell"},{"issue":"11","key":"10.1016\/j.physbeh.2026.115503_bib0022","doi-asserted-by":"crossref","first-page":"2475","DOI":"10.1523\/JNEUROSCI.1724-20.2021","article-title":"Bidirectional regulation of cognitive and anxiety-like behaviors by dentate gyrus mossy cells in male and female mice","volume":"41","author":"Botterill","year":"2021","journal-title":"J. Neurosci."},{"issue":"1","key":"10.1016\/j.physbeh.2026.115503_bib0023","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.cub.2020.09.074","article-title":"Ventro-dorsal hippocampal pathway gates novelty-induced contextual memory formation","volume":"31","author":"Fredes","year":"2021","journal-title":"Curr. Biol."},{"issue":"1","key":"10.1016\/j.physbeh.2026.115503_bib0024","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1016\/0006-291X(89)91757-9","article-title":"Isolation of a novel 38 residue-hypothalamic polypeptide which stimulates adenylate cyclase in pituitary cells","volume":"164","author":"Miyata","year":"1989","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"3","key":"10.1016\/j.physbeh.2026.115503_bib0025","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1124\/pr.109.001370","article-title":"Pituitary adenylate cyclase-activating polypeptide and its receptors: 20 years after the discovery","volume":"61","author":"Vaudry","year":"2009","journal-title":"Pharmacol. Rev."},{"issue":"4","key":"10.1016\/j.physbeh.2026.115503_bib0026","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1016\/j.neuroscience.2009.11.023","article-title":"Stress hormone synthesis in mouse hypothalamus and adrenal gland triggered by restraint is dependent on pituitary adenylate cyclase-activating polypeptide signaling","volume":"165","author":"Stroth","year":"2010","journal-title":"Neuroscience"},{"issue":"7335","key":"10.1016\/j.physbeh.2026.115503_bib0027","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1038\/nature09856","article-title":"Post-traumatic stress disorder is associated with PACAP and the PAC1 receptor","volume":"470","author":"Ressler","year":"2011","journal-title":"Nature"},{"key":"10.1016\/j.physbeh.2026.115503_bib0028","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.nlm.2018.11.011","article-title":"PACAP increases arc\/arg 3.1 expression within the extended amygdala after fear conditioning in rats","volume":"157","author":"Meloni","year":"2019","journal-title":"Neurobiol. Learn Mem."},{"issue":"4","key":"10.1016\/j.physbeh.2026.115503_bib0029","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1002\/(SICI)1096-9861(19960805)371:4<567::AID-CNE6>3.0.CO;2-2","article-title":"Distribution of the mRNA for a pituitary adenylate cyclase-activating polypeptide receptor in the rat brain: an in situ hybridization study","volume":"371","author":"Hashimoto","year":"1996","journal-title":"J. Comp. Neurol."},{"issue":"1","key":"10.1016\/j.physbeh.2026.115503_bib0030","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/S0165-3806(99)00192-3","article-title":"Developmental regulation of pituitary adenylate cyclase-activating polypeptide and PAC(1) receptor mRNA expression in the rat central nervous system","volume":"120","author":"Jaworski","year":"2000","journal-title":"Brain Res. Dev. Brain Res."},{"key":"10.1016\/j.physbeh.2026.115503_bib0031","article-title":"Behavioral role of PACAP signaling reflects its selective distribution in glutamatergic and GABAergic neuronal subpopulations","volume":"10","author":"Zhang","year":"2021","journal-title":"eLife"},{"key":"10.1016\/j.physbeh.2026.115503_bib0032","doi-asserted-by":"crossref","DOI":"10.1016\/j.peptides.2021.170554","article-title":"PACAP orchestration of stress-related responses in neural circuits","volume":"142","author":"Boucher","year":"2021","journal-title":"Peptides"},{"key":"10.1016\/j.physbeh.2026.115503_bib0033","doi-asserted-by":"crossref","first-page":"111","DOI":"10.3389\/fncel.2020.00111","article-title":"The role of pituitary adenylate cyclase-activating polypeptide (PACAP) signaling in the hippocampal dentate gyrus","volume":"14","author":"Johnson","year":"2020","journal-title":"Front. Cell Neurosci."},{"issue":"2","key":"10.1016\/j.physbeh.2026.115503_bib0034","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1016\/j.bbr.2010.02.009","article-title":"Environmental factors during early developmental period influence psychobehavioral abnormalities in adult PACAP-deficient mice","volume":"209","author":"Ishihama","year":"2010","journal-title":"Behav. Brain Res."},{"issue":"5","key":"10.1016\/j.physbeh.2026.115503_bib0035","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1016\/j.psyneuen.2012.09.006","article-title":"PACAP-deficient mice show attenuated corticosterone secretion and fail to develop depressive behavior during chronic social defeat stress","volume":"38","author":"Lehmann","year":"2013","journal-title":"Psychoneuroendocrinology"},{"issue":"15","key":"10.1016\/j.physbeh.2026.115503_bib0036","doi-asserted-by":"crossref","first-page":"5520","DOI":"10.1523\/JNEUROSCI.21-15-05520.2001","article-title":"Impairment of mossy fiber long-term potentiation and associative learning in pituitary adenylate cyclase activating polypeptide type I receptor-deficient mice","volume":"21","author":"Otto","year":"2001","journal-title":"J. Neurosci."},{"key":"10.1016\/j.physbeh.2026.115503_bib0037","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.nlm.2014.11.014","article-title":"PACAP modulates the consolidation and extinction of the contextual fear conditioning through NMDA receptors","volume":"118","author":"Schmidt","year":"2015","journal-title":"Neurobiol. Learn Mem."},{"issue":"18","key":"10.1016\/j.physbeh.2026.115503_bib0038","doi-asserted-by":"crossref","first-page":"3827","DOI":"10.1002\/cne.24035","article-title":"High-resolution characterization of a PACAP-EGFP transgenic mouse model for mapping PACAP-expressing neurons","volume":"524","author":"Condro","year":"2016","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.physbeh.2026.115503_bib0039","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.brainres.2012.09.043","article-title":"Pharmacosynthetics: reimagining the pharmacogenetic approach","volume":"1511","author":"Farrell","year":"2013","journal-title":"Brain Res."},{"issue":"12","key":"10.1016\/j.physbeh.2026.115503_bib0040","doi-asserted-by":"crossref","first-page":"3559","DOI":"10.1016\/j.celrep.2017.11.089","article-title":"Modulation of SF1 neuron activity coordinately regulates both feeding behavior and associated emotional states","volume":"21","author":"Viskaitis","year":"2017","journal-title":"Cell Rep."},{"issue":"9","key":"10.1016\/j.physbeh.2026.115503_bib0041","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2022.110882","article-title":"A cholinergic medial septum input to medial habenula mediates generalization formation and extinction of visual aversion","volume":"39","author":"Mu","year":"2022","journal-title":"Cell Rep."},{"issue":"4","key":"10.1016\/j.physbeh.2026.115503_bib0042","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1016\/j.neuron.2014.04.008","article-title":"Chemogenetic synaptic silencing of neural circuits localizes a hypothalamus\u2192midbrain pathway for feeding behavior","volume":"82","author":"Stachniak","year":"2014","journal-title":"Neuron"},{"issue":"8","key":"10.1016\/j.physbeh.2026.115503_bib0043","doi-asserted-by":"crossref","first-page":"1880","DOI":"10.1038\/npp.2014.35","article-title":"Chemogenetic inactivation of ventral hippocampal glutamatergic neurons disrupts consolidation of contextual fear memory","volume":"39","author":"Zhu","year":"2014","journal-title":"Neuropsychopharmacology"},{"issue":"1","key":"10.1016\/j.physbeh.2026.115503_bib0044","doi-asserted-by":"crossref","first-page":"2501","DOI":"10.1038\/s41467-020-16198-5","article-title":"nNOS-expressing neurons in the vmPFC transform pPVT-derived chronic pain signals into anxiety behaviors","volume":"11","author":"Liang","year":"2020","journal-title":"Nat. Commun."},{"key":"10.1016\/j.physbeh.2026.115503_bib0045","doi-asserted-by":"crossref","first-page":"9","DOI":"10.7554\/eLife.53945","article-title":"Different dendritic domains of the GnRH neuron underlie the pulse and surge modes of GnRH secretion in female mice","volume":"9","author":"Wang","year":"2020","journal-title":"ELife"},{"key":"10.1016\/j.physbeh.2026.115503_bib0047","author":"Sinha","year":"2025","journal-title":"Non-parametric alternative of 2-way ANOVA (ScheirerRayHare)"},{"issue":"3","key":"10.1016\/j.physbeh.2026.115503_bib0064","doi-asserted-by":"crossref","first-page":"264","DOI":"10.3758\/BF03205285","article-title":"Factors governing one-trial contextual conditioning","volume":"18","author":"Fanselow","year":"1990","journal-title":"Anim. Learn Behav."},{"key":"10.1016\/j.physbeh.2026.115503_bib0065","series-title":"Classical Conditioning II: Current Research and Theory","first-page":"64","article-title":"A theory of Pavlovian conditioning: variations on the effectiveness of reinforcement and non-reinforcement","author":"Rescorla","year":"1972"},{"issue":"2","key":"10.1016\/j.physbeh.2026.115503_bib0052","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1111\/1749-4877.12892","article-title":"Defensive behaviors and c-fos expression in the midbrain","volume":"20","author":"Yavas","year":"2025","journal-title":"Integr. Zool."},{"issue":"4","key":"10.1016\/j.physbeh.2026.115503_bib0048","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1101\/lm.053612.122","article-title":"Specific behaviors during auditory fear conditioning and postsynaptic expression of AMPA receptors in the basolateral amygdala predict interindividual differences in fear generalization in male rats","volume":"30","author":"Moraes","year":"2023","journal-title":"Lear. Mem."},{"key":"10.1016\/j.physbeh.2026.115503_bib0049","doi-asserted-by":"crossref","first-page":"10","DOI":"10.7554\/eLife.64988","article-title":"The structure of behavioral variation within a genotype","volume":"10","author":"Werkhoven","year":"2021","journal-title":"ELife"},{"issue":"1","key":"10.1016\/j.physbeh.2026.115503_bib0066","doi-asserted-by":"crossref","first-page":"4374","DOI":"10.1038\/s41467-022-31442-w","article-title":"PACAP-PAC1R modulates fear extinction via the ventromedial hypothalamus","volume":"13","author":"Velasco","year":"2022","journal-title":"Nat. Commun."},{"issue":"1","key":"10.1016\/j.physbeh.2026.115503_bib0050","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1037\/h0028589","article-title":"Species-specific defense reactions and avoidance learning","volume":"77","author":"Bolles","year":"1970","journal-title":"Psychol. Rev."},{"issue":"3","key":"10.1016\/j.physbeh.2026.115503_bib0051","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1901\/jeab.1988.50-361","article-title":"Changes in feeding and foraging patterns as an antipredator defensive strategy: a laboratory simulation using aversive stimulation in a closed economy","volume":"50","author":"Fanselow","year":"1988","journal-title":"J. Exp. Anal. Behav."},{"issue":"2","key":"10.1016\/j.physbeh.2026.115503_bib0053","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1037\/0735-7044.121.2.335","article-title":"Spatial exploration is required for the formation of contextual fear memory","volume":"121","author":"McHugh","year":"2007","journal-title":"Behav. Neurosci."},{"issue":"1","key":"10.1016\/j.physbeh.2026.115503_bib0054","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1006\/nlme.2001.4014","article-title":"Pituitary adenylate cyclase-activating polypeptide hormone (PACAP) at very low dosages improves memory in the rat","volume":"76","author":"Sacchetti","year":"2001","journal-title":"Neurobiol. Learn Mem."},{"key":"10.1016\/j.physbeh.2026.115503_bib0055","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbr.2020.112771","article-title":"Contextual processing elicits sex differences in dorsal hippocampus activation following footshock and context fear retrieval","volume":"393","author":"Colon","year":"2020","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.physbeh.2026.115503_bib0056","doi-asserted-by":"crossref","first-page":"13","DOI":"10.3389\/fnbeh.2019.00056","article-title":"Sex differences in remote contextual fear generalization in mice","volume":"13","author":"Asok","year":"2019","journal-title":"Front. Behav. Neurosci."},{"key":"10.1016\/j.physbeh.2026.115503_bib0057","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbr.2020.112623","article-title":"Sex differences in behavioral responses during a conditioned flight paradigm","volume":"389","author":"Borkar","year":"2020","journal-title":"Behav. Brain Res."},{"issue":"4","key":"10.1016\/j.physbeh.2026.115503_bib0058","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1016\/j.cell.2016.09.051","article-title":"Distinct hippocampal pathways mediate dissociable roles of context in memory retrieval","volume":"167","author":"Xu","year":"2016","journal-title":"Cell"},{"key":"10.1016\/j.physbeh.2026.115503_bib0059","doi-asserted-by":"crossref","first-page":"1454","DOI":"10.3389\/fpsyg.2017.01454","article-title":"The influences of emotion on learning and memory","volume":"8","author":"Tyng","year":"2017","journal-title":"Front. Psychol."},{"issue":"3","key":"10.1016\/j.physbeh.2026.115503_bib0060","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1038\/s41593-018-0073-9","article-title":"Hippocampus-driven feed-forward inhibition of the prefrontal cortex mediates relapse of extinguished fear","volume":"21","author":"Marek","year":"2018","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.physbeh.2026.115503_bib0061","doi-asserted-by":"crossref","DOI":"10.1016\/j.nlm.2023.107832","article-title":"Ventral hippocampal projections to infralimbic cortex and basolateral amygdala are differentially activated by contextual fear and extinction recall","volume":"205","author":"Brockway","year":"2023","journal-title":"Neurobiol. Learn Mem."},{"key":"10.1016\/j.physbeh.2026.115503_bib0062","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuropharm.2025.110430","article-title":"Chronic social stress induces generalized hyper-sensitivity to aversion: a mouse model with translational validity for understanding and treating negative valence disorders","volume":"273","author":"Poggi","year":"2025","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.physbeh.2026.115503_bib0063","doi-asserted-by":"crossref","DOI":"10.1016\/j.ynstr.2026.100823","article-title":"The progesterone to estradiol ratio predicts fear extinction in mice and humans","volume":"43","author":"Nab\u00e1s","year":"2026","journal-title":"Neurobiol. Stress"}],"container-title":["Physiology &amp; Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0031938426002866?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0031938426002866?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T21:16:22Z","timestamp":1791666982000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0031938426002866"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,12]]},"references-count":65,"alternative-id":["S0031938426002866"],"URL":"https:\/\/doi.org\/10.1016\/j.physbeh.2026.115503","relation":{},"ISSN":["0031-9384"],"issn-type":[{"value":"0031-9384","type":"print"}],"subject":[],"published":{"date-parts":[[2026,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"PACAP neurons of the ventral dentate gyrus are not involved in fear acquisition","name":"articletitle","label":"Article Title"},{"value":"Physiology & Behavior","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.physbeh.2026.115503","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"115503"}}