{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T01:45:23Z","timestamp":1791942323023,"version":"4.3.4"},"reference-count":68,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T00:00:00Z","timestamp":1790121600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000038","name":"Natural Sciences and Engineering Research Council of Canada","doi-asserted-by":"publisher","award":["RGPIN\/03773-2016"],"award-info":[{"award-number":["RGPIN\/03773-2016"]}],"id":[{"id":"10.13039\/501100000038","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Physiology &amp; Behavior"],"published-print":{"date-parts":[[2027,1]]},"DOI":"10.1016\/j.physbeh.2026.115516","type":"journal-article","created":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T23:15:33Z","timestamp":1790205333000},"page":"115516","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Human milk oligosaccharide supplementation in post-weaning rats fed a high fat\/sucrose diet affects glutamate receptor gene expression in the nucleus accumbens and amygdala"],"prefix":"10.1016","volume":"318","author":[{"given":"Erin W","family":"Noye Tuplin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tyra","family":"Fernandes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dana E","family":"Lowry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0553-1754","authenticated-orcid":false,"given":"Nicole A","family":"Cho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kate M","family":"Sales","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Riley A","family":"Patterson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5088-7947","authenticated-orcid":false,"given":"Raylene A","family":"Reimer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"8","key":"10.1016\/j.physbeh.2026.115516_bib0001","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1038\/s41574-019-0219-1","article-title":"From conception to infancy - early risk factors for childhood obesity","volume":"15","author":"Larqu\u00e9","year":"2019","journal-title":"Nat. Rev. Endocrinol."},{"key":"10.1016\/j.physbeh.2026.115516_bib0002","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1111\/j.1467-789X.2007.00318.x","article-title":"Breastfeeding, early growth and later obesity","volume":"8","author":"Singhal","year":"2007","journal-title":"Obes. Rev."},{"key":"10.1016\/j.physbeh.2026.115516_bib0003","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1111\/apa.13132","article-title":"Breastfeeding and asthma and allergies: a systematic review and meta-analysis","volume":"104","author":"Lodge","year":"2015","journal-title":"Acta Paediatr."},{"issue":"7","key":"10.1016\/j.physbeh.2026.115516_bib0004","doi-asserted-by":"crossref","first-page":"1812","DOI":"10.1038\/s41390-023-02923-5","article-title":"Early life factors and structural brain network in children with overweight\/obesity: the ActiveBrains project","volume":"95","author":"Solis-Urra","year":"2024","journal-title":"Pediatr. Res."},{"issue":"8","key":"10.1016\/j.physbeh.2026.115516_bib0005","doi-asserted-by":"crossref","first-page":"1310","DOI":"10.1111\/apa.14287","article-title":"Nutritional influences on brain development","volume":"107","author":"Georgieff","year":"2018","journal-title":"Acta Paediatr."},{"issue":"2","key":"10.1016\/j.physbeh.2026.115516_bib0006","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.jcjd.2013.02.059","article-title":"The public health burden of obesity in Canada","volume":"37","author":"Janssen","year":"2013","journal-title":"Can. J. Diabetes"},{"issue":"1","key":"10.1016\/j.physbeh.2026.115516_bib0007","doi-asserted-by":"crossref","first-page":"266","DOI":"10.3390\/nu12010266","article-title":"Human milk oligosaccharides: health benefits, potential applications in infant formulas, and pharmacology","volume":"12","author":"Wici\u0144ski","year":"2020","journal-title":"Nutrients"},{"key":"10.1016\/j.physbeh.2026.115516_bib0008","doi-asserted-by":"crossref","first-page":"44","DOI":"10.3389\/fnint.2020.00044","article-title":"Gut-brain axis in the early postnatal years of life: a developmental perspective","volume":"14","author":"Jena","year":"2020","journal-title":"Front. Integr. Neurosci."},{"issue":"4","key":"10.1016\/j.physbeh.2026.115516_bib0009","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1093\/jn\/nxaa427","article-title":"Longitudinal changes in human milk oligosaccharides (HMOs) over the course of 24 months of lactation","volume":"151","author":"Plows","year":"2021","journal-title":"J. Nutr."},{"issue":"11","key":"10.1016\/j.physbeh.2026.115516_bib0010","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/j.earlhumdev.2015.08.013","article-title":"Human breast milk: a review on its composition and bioactivity","volume":"91","author":"Andreas","year":"2015","journal-title":"Early Hum. Dev."},{"issue":"7","key":"10.1016\/j.physbeh.2026.115516_bib0011","doi-asserted-by":"crossref","first-page":"1613","DOI":"10.3390\/nu11071613","article-title":"Gut microbiome: profound implications for diet and disease","volume":"11","author":"Hills","year":"2019","journal-title":"Nutrients"},{"key":"10.1016\/j.physbeh.2026.115516_bib0012","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2019\/2390240","article-title":"Human milk oligosaccharides: the journey ahead","volume":"2019","author":"Ray","year":"2019","journal-title":"Int. J. Pediatr."},{"key":"10.1016\/j.physbeh.2026.115516_bib67","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1146\/annurev-med-042320-014032","article-title":"The gut-brain axis","volume":"73","author":"Mayer","year":"2022","journal-title":"Annu. Rev. Med."},{"key":"10.1016\/j.physbeh.2026.115516_bib0013","doi-asserted-by":"crossref","DOI":"10.3389\/fpsyt.2018.00044","article-title":"Vagus nerve as modulator of the brain\u2013gut axis in psychiatric and inflammatory disorders","volume":"9","author":"Breit","year":"2018","journal-title":"Front. Psychiatry"},{"issue":"7804","key":"10.1016\/j.physbeh.2026.115516_bib0014","doi-asserted-by":"crossref","first-page":"511-+","DOI":"10.1038\/s41586-020-2199-7","article-title":"The gut-brain axis mediates sugar preference","volume":"580","author":"Tan","year":"2020","journal-title":"Nature"},{"key":"10.1016\/j.physbeh.2026.115516_bib0015","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1002\/prp2.70027","article-title":"The gut\u2013brain axis in appetite, satiety, food intake, and eating behavior: insights from animal models and human studies","volume":"12","author":"Clarke","year":"2024","journal-title":"Pharmacol. Res. Perspect."},{"issue":"5","key":"10.1016\/j.physbeh.2026.115516_bib0016","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1016\/j.cell.2017.01.025","article-title":"Gut-brain cross-talk in metabolic control","volume":"168","author":"Clemmensen","year":"2017","journal-title":"Cell"},{"issue":"5","key":"10.1016\/j.physbeh.2026.115516_bib0017","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1017\/S204017441200030X","article-title":"Perinatal overnutrition and the programming of food preferences: pathways and mechanisms","volume":"3","author":"Ong","year":"2012","journal-title":"J. Dev. Orig. Health Dis."},{"issue":"4","key":"10.1016\/j.physbeh.2026.115516_bib0018","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1016\/j.neuroscience.2009.05.029","article-title":"Early life exposure to a high fat diet promotes long-term changes in dietary preferences and central reward signaling","volume":"162","author":"Teegarden","year":"2009","journal-title":"Neuroscience"},{"key":"10.1016\/j.physbeh.2026.115516_bib0019","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/bies.201700172","article-title":"Gutsy moves: the amygdala as a critical node in microbiota to brain signaling","volume":"40","author":"Cowan","year":"2018","journal-title":"Bioessays"},{"key":"10.1016\/j.physbeh.2026.115516_bib0067","doi-asserted-by":"crossref","unstructured":"Ousey J, Boktor JC, Mazmanian SK. Gut microbiota suppress feeding induced by palatable foods. Curr Biol 33(1):147-157.","DOI":"10.1016\/j.cub.2022.10.066"},{"key":"10.1016\/j.physbeh.2026.115516_bib0020","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.neures.2020.01.001","article-title":"Microbial colonization history modulates anxiety-like and complex social behavior in mice","volume":"168","author":"Kamimura","year":"2021","journal-title":"Neurosci. Res."},{"key":"10.1016\/j.physbeh.2026.115516_bib0021","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1126\/scitranslmed.3009759","article-title":"The gut microbiota influences blood-brain barrier permeability in mice","volume":"6","author":"Braniste","year":"2014","journal-title":"Sci. Transl. Med."},{"issue":"4","key":"10.1016\/j.physbeh.2026.115516_bib0022","doi-asserted-by":"crossref","first-page":"1877","DOI":"10.1152\/physrev.00018.2018","article-title":"The microbiota-gut-brain axis","volume":"99","author":"Cryan","year":"2019","journal-title":"Physiol. Rev."},{"issue":"6","key":"10.1016\/j.physbeh.2026.115516_bib0023","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1016\/j.neuron.2007.06.001","article-title":"The role of the GluR2 subunit in AMPA receptor function and synaptic plasticity","volume":"54","author":"Isaac","year":"2007","journal-title":"Neuron"},{"key":"10.1016\/j.physbeh.2026.115516_bib0024","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/j.neuroscience.2021.02.006","article-title":"The effects of human milk oligosaccharide supplementation during critical periods of development on the mesolimbic dopamine system","volume":"459","author":"Tuplin","year":"2021","journal-title":"Neuroscience"},{"issue":"5","key":"10.1016\/j.physbeh.2026.115516_bib0025","doi-asserted-by":"crossref","first-page":"2204","DOI":"10.1152\/jn.2000.84.5.2204","article-title":"Postnatal development of electrophysiological properties of nucleus accumbens neurons","volume":"84","author":"Belleau","year":"2000","journal-title":"J. Neurophysiol."},{"issue":"5","key":"10.1016\/j.physbeh.2026.115516_bib0026","doi-asserted-by":"crossref","first-page":"1362","DOI":"10.1002\/oby.23731","article-title":"Select human milk oligosaccharide supplementation in post-weanling rats affects metabolism and gut microbiota into adulthood","volume":"31","author":"Noye Tuplin","year":"2023","journal-title":"Obesity"},{"issue":"11","key":"10.1016\/j.physbeh.2026.115516_bib0027","doi-asserted-by":"crossref","first-page":"1939","DOI":"10.1093\/jn\/123.11.1939","article-title":"AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet","volume":"123","author":"Reeves","year":"1993","journal-title":"J. Nutr."},{"issue":"2","key":"10.1016\/j.physbeh.2026.115516_bib0028","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1017\/S0954422410000168","article-title":"High-fat diet-induced obesity in animal models","volume":"23","author":"Hariri","year":"2010","journal-title":"Nutr. Res. Rev."},{"issue":"5","key":"10.1016\/j.physbeh.2026.115516_bib0029","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1016\/0026-0495(95)90123-X","article-title":"Differential effects of fat and sucrose on the development of obesity and diabetes in C57BL\/6J and A\/J mice","volume":"44","author":"Surwit","year":"1995","journal-title":"Metabolism"},{"issue":"2","key":"10.1016\/j.physbeh.2026.115516_bib0030","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1038\/nprot.2007.44","article-title":"The use of the elevated plus maze as an assay of anxiety-related behavior in rodents","volume":"2","author":"Walf","year":"2007","journal-title":"Nat. Protoc."},{"issue":"88","key":"10.1016\/j.physbeh.2026.115516_bib0031","doi-asserted-by":"crossref","DOI":"10.3791\/51575-v","article-title":"Fat preference: a novel model of eating behavior in rats","author":"Kasper","year":"2014","journal-title":"J. Vis. Exp."},{"issue":"3","key":"10.1016\/j.physbeh.2026.115516_bib0032","doi-asserted-by":"crossref","first-page":"R622","DOI":"10.1152\/ajpregu.00087.2009","article-title":"Repeated binge access to a palatable food alters feeding behavior, hormone profile, and hindbrain c-Fos responses to a test meal in adult male rats","volume":"297","author":"Bello","year":"2009","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.physbeh.2026.115516_bib0033","doi-asserted-by":"crossref","DOI":"10.1186\/1471-2105-7-123","article-title":"Detecting outliers when fitting data with nonlinear regression - a new method based on robust nonlinear regression and the false discovery rate","volume":"7","author":"Motulsky","year":"2006","journal-title":"Bmc Bioinform."},{"key":"10.1016\/j.physbeh.2026.115516_bib0034","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1096\/fj.202101750R","article-title":"Dietary fiber combinations to mitigate the metabolic, microbial, and cognitive imbalances resulting from diet-induced obesity in rats","volume":"36","author":"Noye Tuplin","year":"2022","journal-title":"FASEB J."},{"issue":"1-2","key":"10.1016\/j.physbeh.2026.115516_bib0035","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/S0166-4328(02)00282-6","article-title":"Motivational views of reinforcement: implications for understanding the behavioral functions of nucleus accumbens dopamine","volume":"137","author":"Salamone","year":"2002","journal-title":"Behav. Brain Res."},{"issue":"4","key":"10.1016\/j.physbeh.2026.115516_bib0036","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1503\/jpn.120060","article-title":"Mood-congruent amygdala responses to subliminally presented facial expressions in major depression: associations with anhedonia","volume":"38","author":"Stuhrmann","year":"2013","journal-title":"J. Psychiatry Neurosci."},{"issue":"1","key":"10.1016\/j.physbeh.2026.115516_bib0037","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1186\/s12916-023-03071-7","article-title":"Association of breastfeeding with mental disorders in mother and child: a systematic review and meta-analysis","volume":"21","author":"Bugaeva","year":"2023","journal-title":"BMC Med."},{"issue":"11","key":"10.1016\/j.physbeh.2026.115516_bib0038","doi-asserted-by":"crossref","first-page":"3572","DOI":"10.3390\/nu12113572","article-title":"The protective and long-lasting effects of human milk oligosaccharides on cognition in mammals","volume":"12","author":"Docq","year":"2020","journal-title":"Nutrients"},{"key":"10.1016\/j.physbeh.2026.115516_bib0039","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuropharm.2023.109772","article-title":"Effects of junk-food on food-motivated behavior and nucleus accumbens glutamate plasticity; insights into the mechanism of calcium-permeable AMPA receptor recruitment","volume":"242","author":"Fetterly","year":"2024","journal-title":"Neuropharmacology"},{"issue":"26","key":"10.1016\/j.physbeh.2026.115516_bib0040","doi-asserted-by":"crossref","first-page":"11999","DOI":"10.1073\/pnas.0913004107","article-title":"Perisynaptic GluR2-lacking AMPA receptors control the reversibility of synaptic and spines modifications","volume":"107","author":"Yang","year":"2010","journal-title":"Proc. Natl Acad. Sci. U S A"},{"key":"10.1016\/j.physbeh.2026.115516_bib0041","doi-asserted-by":"crossref","first-page":"5","DOI":"10.3390\/nu12051532","article-title":"Human milk oligosaccharide supplementation affects intestinal barrier function and microbial composition in the gastrointestinal tract of young Sprague Dawley rats","volume":"12","author":"Chleilat","year":"2020","journal-title":"Nutrients"},{"key":"10.1016\/j.physbeh.2026.115516_bib0042","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1523\/ENEURO.0120-17.2017","article-title":"Impact of early consumption of high-fat diet on the mesolimbic dopaminergic system","volume":"4","author":"Naneix","year":"2017","journal-title":"eNeuro"},{"issue":"4","key":"10.1016\/j.physbeh.2026.115516_bib0043","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1016\/j.neuron.2011.02.016","article-title":"Reward mechanisms in obesity: new insights and future directions","volume":"69","author":"Kenny","year":"2011","journal-title":"Neuron"},{"issue":"13","key":"10.1016\/j.physbeh.2026.115516_bib0044","doi-asserted-by":"crossref","first-page":"2977","DOI":"10.1038\/npp.2016.111","article-title":"Eating 'junk-food' produces rapid and long-lasting increases in NAc CP-AMPA receptors: implications for enhanced cue-induced motivation and food addiction","volume":"41","author":"Oginsky","year":"2016","journal-title":"Neuropsychopharmacology"},{"issue":"3","key":"10.1016\/j.physbeh.2026.115516_bib0045","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1038\/s41386-020-0781-1","article-title":"Sex specific effects of \"junk-food\" diet on calcium permeable AMPA receptors and silent synapses in the nucleus accumbens core","volume":"46","author":"Alonso-Caraballo","year":"2021","journal-title":"Neuropsychopharmacology"},{"issue":"8","key":"10.1016\/j.physbeh.2026.115516_bib0046","doi-asserted-by":"crossref","first-page":"1675","DOI":"10.1007\/s00213-013-3294-3","article-title":"Time-dependent decreases in nucleus accumbens AMPA\/NMDA ratio and incubation of sucrose craving in adolescent and adult rats","volume":"231","author":"Counotte","year":"2014","journal-title":"Psychopharmacol. (Berl)"},{"key":"10.1016\/j.physbeh.2026.115516_bib0047","doi-asserted-by":"crossref","DOI":"10.1016\/j.brainresbull.2025.111300","article-title":"Reversing the impact of an obesogenic diet on emotion regulation and brain metabolism: a rat model study","volume":"224","author":"Sal-Sarria","year":"2025","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.physbeh.2026.115516_bib0048","article-title":"Prebiotics modulate the microbiota-gut-brain axis and ameliorate anxiety and depression-like behavior in HFD-fed mice","volume":"182","author":"de Pavia","year":"2024","journal-title":"Food Res. Int."},{"key":"10.1016\/j.physbeh.2026.115516_bib0049","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1002\/mnfr.202200566","article-title":"Administration time and dietary patterns modified the effect of inulin on CUMS-induced anxiety and depression","volume":"67","author":"Chen","year":"2023","journal-title":"Mol. Nutr. Food Res."},{"issue":"6","key":"10.1016\/j.physbeh.2026.115516_bib0050","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1248\/bpb.b22-00803","article-title":"2\u2032-fucosyllactose alleviates early weaning-induced anxiety-like behavior, amygdala hyperactivity, and gut microbiota changes","volume":"46","author":"Araki","year":"2023","journal-title":"Biol. Pharm. Bull."},{"issue":"7","key":"10.1016\/j.physbeh.2026.115516_bib0051","doi-asserted-by":"crossref","first-page":"2854","DOI":"10.1038\/s41380-021-01054-9","article-title":"Sialylated human milk oligosaccharides program cognitive development through a non-genomic transmission mode","volume":"26","author":"Hauser","year":"2021","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.physbeh.2026.115516_bib0052","doi-asserted-by":"crossref","DOI":"10.3389\/fncel.2023.1091890","article-title":"Long-term consequences of reduced availability and compensatory supplementation of sialylated HMOs on cognitive capabilities","volume":"17","author":"Pisa","year":"2023","journal-title":"Front. Cell Neurosci."},{"issue":"41","key":"10.1016\/j.physbeh.2026.115516_bib0053","doi-asserted-by":"crossref","first-page":"10947","DOI":"10.1523\/JNEUROSCI.2603-07.2007","article-title":"A pathway-specific function for different AMPA receptor subunits in amygdala long-term potentiation and fear conditioning","volume":"27","author":"Humeau","year":"2007","journal-title":"J. Neurosci."},{"key":"10.1016\/j.physbeh.2026.115516_bib0054","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.brainresbull.2023.03.001","article-title":"Young adult and aged female rats are vulnerable to amygdala-dependent, but not hippocampus-dependent, memory impairment following short-term high-fat diet","volume":"195","author":"Muscat","year":"2023","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.physbeh.2026.115516_bib0055","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1016\/j.neuropharm.2017.09.041","article-title":"IL-1beta reduces GluA1 phosphorylation and its surface expression during memory reconsolidation and alpha-melanocyte-stimulating hormone can modulate these effects","volume":"128","author":"Machado","year":"2018","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.physbeh.2026.115516_bib0056","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/j.bbi.2018.01.011","article-title":"Exposure to an obesogenic diet during adolescence leads to abnormal maturation of neural and behavioral substrates underpinning fear and anxiety","volume":"70","author":"Vega-Torres","year":"2018","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.physbeh.2026.115516_bib0057","doi-asserted-by":"crossref","DOI":"10.1016\/j.brainres.2024.149327","article-title":"Hyperfunction of AMPA receptors in the amygdala and hippocampus contributes to enhanced fear memory in diabetic mice","volume":"1848","author":"Ikegami","year":"2025","journal-title":"Brain Res."},{"issue":"7","key":"10.1016\/j.physbeh.2026.115516_bib0058","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1016\/j.biopsych.2016.12.031","article-title":"Targeting the microbiota-gut-brain axis: prebiotics have anxiolytic and antidepressant-like effects and reverse the impact of chronic stress in mice","volume":"82","author":"Burokas","year":"2017","journal-title":"Biol. Psychiatry"},{"issue":"1","key":"10.1016\/j.physbeh.2026.115516_bib0059","doi-asserted-by":"crossref","first-page":"G23","DOI":"10.1152\/ajpgi.00233.2022","article-title":"Human milk oligosaccharides reduce necrotizing enterocolitis-induced neuroinflammation and cognitive impairment in mice","volume":"325","author":"Sodhi","year":"2023","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol."},{"issue":"7","key":"10.1016\/j.physbeh.2026.115516_bib0060","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1038\/nn.4030","article-title":"Host microbiota constantly control maturation and function of microglia in the CNS","volume":"18","author":"Erny","year":"2015","journal-title":"Nat. Neurosci."},{"issue":"1","key":"10.1016\/j.physbeh.2026.115516_bib0061","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1186\/s40168-025-02094-x","article-title":"Cognitive and behavioral benefits of 2\u2032-fucosyllactose in growing mice: the roles of 5-hydroxytryptophan and gut microbiota","volume":"13","author":"Zhu","year":"2025","journal-title":"Microbiome"},{"issue":"5","key":"10.1016\/j.physbeh.2026.115516_bib0062","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1016\/j.jnutbio.2014.11.016","article-title":"Effects of a human milk oligosaccharide, 2\u2032-fucosyllactose, on hippocampal long-term potentiation and learning capabilities in rodents","volume":"26","author":"V\u00e1zquez","year":"2015","journal-title":"J. Nutr. Biochem."},{"issue":"20","key":"10.1016\/j.physbeh.2026.115516_bib0063","doi-asserted-by":"crossref","first-page":"6985","DOI":"10.1523\/JNEUROSCI.0115-14.2014","article-title":"Glucagon-like peptide-1 receptor activation in the nucleus accumbens core suppresses feeding by increasing glutamatergic AMPA\/kainate signaling","volume":"34","author":"Mietlicki-Baase","year":"2014","journal-title":"J. Neurosci."},{"issue":"10","key":"10.1016\/j.physbeh.2026.115516_bib0064","doi-asserted-by":"crossref","first-page":"2187","DOI":"10.1046\/j.1460-9568.2003.02642.x","article-title":"Glutamate motivational ensembles in nucleus accumbens: rostrocaudal shell gradients of fear and feeding","volume":"17","author":"Reynolds","year":"2003","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.physbeh.2026.115516_bib0065","doi-asserted-by":"crossref","DOI":"10.3389\/fpsyt.2021.711065","article-title":"Effect of estrous cycle on behavior of females in rodent tests of anxiety","volume":"12","author":"Lovick","year":"2021","journal-title":"Front. Psychiatry"},{"issue":"4-5","key":"10.1016\/j.physbeh.2026.115516_bib0066","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/S0031-9384(01)00593-5","article-title":"Estrous cycle influences the response of female rats in the elevated plus-maze test","volume":"74","author":"Marcondes","year":"2001","journal-title":"Physiol. Behav."}],"container-title":["Physiology &amp; Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0031938426002994?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0031938426002994?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T00:57:51Z","timestamp":1791939471000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0031938426002994"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2027,1]]},"references-count":68,"alternative-id":["S0031938426002994"],"URL":"https:\/\/doi.org\/10.1016\/j.physbeh.2026.115516","relation":{},"ISSN":["0031-9384"],"issn-type":[{"value":"0031-9384","type":"print"}],"subject":[],"published":{"date-parts":[[2027,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Human milk oligosaccharide supplementation in post-weaning rats fed a high fat\/sucrose diet affects glutamate receptor gene expression in the nucleus accumbens and amygdala","name":"articletitle","label":"Article Title"},{"value":"Physiology & Behavior","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.physbeh.2026.115516","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Author(s). Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"115516"}}