{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T07:38:59Z","timestamp":1792741139399,"version":"4.5.0"},"reference-count":54,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001807","name":"State of Sao Paulo Research Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordination for the improvement of Higher Education Personnel","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"National Council for Scientific and Technological Development","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004809","name":"Finep","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Physiology &amp; Behavior"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1016\/j.physbeh.2026.115539","type":"journal-article","created":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T07:04:11Z","timestamp":1792739051000},"page":"115539","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Gene-Environment Interaction in Transgenic Rats overexpressing human DISC1: Effects of Early Social Isolation on Behavioral Domains"],"prefix":"10.1016","author":[{"given":"Giulia dos Santos","family":"Pedroso-Fidelis","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernando Callas","family":"Avila","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jo\u00e3o Victor","family":"Nani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucas de Carvalho","family":"Porta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nat\u00e1lia Bonetti","family":"Bertagna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ben Tagami","family":"Rodolpho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard S.","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F\u00e1bio Cardoso","family":"Cruz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mirian Akemi Furuie","family":"Hayashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.physbeh.2026.115539_bib0001","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1111\/jcpp.13113","article-title":"The p factor: genetic analyses support a general dimension of psychopathology in childhood and adolescence","volume":"61","author":"Allegrini","year":"2020","journal-title":"J Child Psychol Psychiatry"},{"issue":"6","key":"10.1016\/j.physbeh.2026.115539_bib0002","doi-asserted-by":"crossref","DOI":"10.1002\/brb3.3604","article-title":"Resocialization mitigates depressive behaviors induced by social isolation stress in mice: attenuation of hippocampal neuroinflammation and nitrite level","volume":"14","author":"Amini\u2011Khoei","year":"2024","journal-title":"Brain Behav"},{"issue":"2","key":"10.1016\/j.physbeh.2026.115539_bib0003","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1093\/ilar.47.2.124","article-title":"Behavioral phenotyping of transgenic and knockout mice: practical concerns and potential pitfalls","volume":"47","author":"Bailey","year":"2006","journal-title":"ILAR J"},{"issue":"1","key":"10.1016\/j.physbeh.2026.115539_bib0004","doi-asserted-by":"crossref","first-page":"123","DOI":"10.3390\/diagnostics11010123","article-title":"Animal models of depression: What can they teach us about the human disease?","volume":"11","author":"Becker","year":"2021","journal-title":"Diagnostics (Basel)"},{"issue":"10","key":"10.1016\/j.physbeh.2026.115539_bib0005","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0240439","article-title":"Social isolation in rats: Effects on animal welfare and molecular markers for neuroplasticity","volume":"15","author":"Begni","year":"2020","journal-title":"PLoS One"},{"issue":"7","key":"10.1016\/j.physbeh.2026.115539_bib0006","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1038\/s41380-018-0133-2","article-title":"Protein misassembly and aggregation as potential convergence points for non-genetic causes of chronic mental illness","volume":"24","author":"Bradshaw","year":"2019","journal-title":"Mol Psychiatry"},{"issue":"3","key":"10.1016\/j.physbeh.2026.115539_bib0007","doi-asserted-by":"crossref","first-page":"281","DOI":"10.31887\/DCNS.2012.14.3\/pchaste","article-title":"Autism risk factors: genes, environment, and gene-environment interactions","volume":"14","author":"Chaste","year":"2012","journal-title":"Dialogues Clin Neurosci"},{"issue":"2","key":"10.1016\/j.physbeh.2026.115539_bib0008","doi-asserted-by":"crossref","first-page":"1","DOI":"10.18637\/jss.v034.i02","article-title":"Beta regression in R","volume":"34","author":"Cribari-Neto","year":"2010","journal-title":"J Stat Softw"},{"issue":"1","key":"10.1016\/j.physbeh.2026.115539_bib0009","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1601-183X.2008.00438.x","article-title":"Standards for the publication of mouse mutant studies","volume":"8","author":"Crusio","year":"2009","journal-title":"Genes Brain Behav"},{"key":"10.1016\/j.physbeh.2026.115539_bib0010","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.schres.2019.02.021","article-title":"Ndel1 oligopeptidase activity as a potential biomarker of early stages of schizophrenia","volume":"208","author":"Dal Mas","year":"2019","journal-title":"Schizophr Res"},{"key":"10.1016\/j.physbeh.2026.115539_bib0011","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.jad.2018.10.001","article-title":"Oligopeptidases activity in bipolar disorder: Ndel1 and angiotensin I converting enzyme","volume":"244","author":"Dal Mas","year":"2019","journal-title":"J Affect Disord"},{"key":"10.1016\/j.physbeh.2026.115539_bib0012","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2022.114181","article-title":"Social isolation from early life induces anxiety-like behaviors in adult rats: Relation to neuroendocrine and neurochemical dysfunctions","volume":"158","author":"Dimonte","year":"2023","journal-title":"Biomed Pharmacother"},{"issue":"6","key":"10.1016\/j.physbeh.2026.115539_bib0013","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.1016\/j.neubiorev.2008.03.003","article-title":"Behavioural and neurochemical effects of post-weaning social isolation in rodents: relevance to developmental neuropsychiatric disorders","volume":"32","author":"Fone","year":"2008","journal-title":"Neurosci Biobehav Rev"},{"issue":"10543","key":"10.1016\/j.physbeh.2026.115539_bib0014","doi-asserted-by":"crossref","first-page":"2040","DOI":"10.1016\/S0140-6736(26)00519-2","article-title":"Updated trends in the global prevalence and burden of mental disorders, 1990\u20132023: a systematic analysis for the Global Burden of Disease Study 2023","volume":"407","year":"2026","journal-title":"The Lancet"},{"key":"10.1016\/j.physbeh.2026.115539_bib0015","unstructured":"Hartig F. DHARMa: Residual diagnostics for hierarchical (multi-level\/mixed) regression models [computer program]. Version 0.4.7; 2024."},{"key":"10.1016\/j.physbeh.2026.115539_bib0016","doi-asserted-by":"crossref","first-page":"364","DOI":"10.3389\/fnbeh.2015.00364","article-title":"Ethological evaluation of the effects of social defeat stress in mice: beyond the social interaction ratio","volume":"9","author":"Henriques-Alves","year":"2016","journal-title":"Front Behav Neurosci"},{"issue":"2","key":"10.1016\/j.physbeh.2026.115539_bib0017","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1016\/j.physbeh.2010.12.019","article-title":"Post-weaning chronic social isolation produces profound behavioral dysregulation with decreases in prefrontal cortex synaptic-associated protein expression in female rats","volume":"104","author":"Hermes","year":"2011","journal-title":"Physiol Behav"},{"issue":"2","key":"10.1016\/j.physbeh.2026.115539_bib0018","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/j.physbeh.2011.08.036","article-title":"Social isolation in adolescence alters behaviors in the forced swim and sucrose preference tests in female but not in male rats","volume":"105","author":"Hong","year":"2012","journal-title":"Physiol Behav"},{"issue":"1","key":"10.1016\/j.physbeh.2026.115539_bib0019","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1093\/schbul\/sbq135","article-title":"DISC1 in schizophrenia: genetic mouse models and human genomic imaging","volume":"37","author":"Johnstone","year":"2011","journal-title":"Schizophr Bull"},{"key":"10.1016\/j.physbeh.2026.115539_bib0020","doi-asserted-by":"crossref","DOI":"10.1016\/j.pbb.2021.173168","article-title":"Sex differences in the elevated plus-maze test and large open field test in adult Wistar rats","volume":"204","author":"Knight","year":"2021","journal-title":"Pharmacol Biochem Behav"},{"issue":"2","key":"10.1016\/j.physbeh.2026.115539_bib0021","doi-asserted-by":"crossref","first-page":"134","DOI":"10.4161\/pri.18989","article-title":"Aggregated proteins in schizophrenia and other chronic mental diseases: DISC1opathies","volume":"6","author":"Korth","year":"2012","journal-title":"Prion"},{"key":"10.1016\/j.physbeh.2026.115539_bib0022","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1007\/978-1-4939-8994-2_5","article-title":"The Forced Swim Test for Depression-Like Behavior in Rodents","volume":"1916","author":"Kraeuter","year":"2019","journal-title":"Methods Mol Biol"},{"key":"10.1016\/j.physbeh.2026.115539_bib0023","unstructured":"Lenth R, Piaskowski J. emmeans: Estimated marginal means, aka least-squares means [computer program]. Version 2.0.2; 2026."},{"issue":"2","key":"10.1016\/j.physbeh.2026.115539_bib0024","doi-asserted-by":"crossref","DOI":"10.1002\/dev.70129","article-title":"Factors modulating the effects of juvenile social isolation on adult social behavior in rodents","volume":"68","author":"Leventhal","year":"2026","journal-title":"Dev Psychobiol"},{"key":"10.1016\/j.physbeh.2026.115539_bib0025","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.brainres.2012.01.005","article-title":"Post-weaning social isolation of female rats, anxiety-related behavior, and serotonergic systems","volume":"1443","author":"Lukkes","year":"2012","journal-title":"Brain Res"},{"key":"10.1016\/j.physbeh.2026.115539_bib0026","doi-asserted-by":"crossref","first-page":"18","DOI":"10.3389\/neuro.08.018.2009","article-title":"Consequences of post-weaning social isolation on anxiety behavior and related neural circuits in rodents","volume":"3","author":"Lukkes","year":"2009","journal-title":"Front Behav Neurosci"},{"issue":"6","key":"10.1016\/j.physbeh.2026.115539_bib0027","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1038\/nrn3492","article-title":"The contextual brain: implications for fear conditioning, extinction and psychopathology","volume":"14","author":"Maren","year":"2013","journal-title":"Nat Rev Neurosci"},{"issue":"8","key":"10.1016\/j.physbeh.2026.115539_bib0028","doi-asserted-by":"crossref","first-page":"2537","DOI":"10.1007\/s00221-021-06149-x","article-title":"Paradoxical changes in mood-related behaviors on continuous social isolation after weaning","volume":"239","author":"Matsumoto","year":"2021","journal-title":"Exp Brain Res"},{"issue":"12","key":"10.1016\/j.physbeh.2026.115539_bib0029","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.3390\/brainsci14121287","article-title":"5-HT\u2082C receptors in the BNST modulate contextual fear conditioning without affecting acute early life stress-enhanced fear learning in adult rats","volume":"14","author":"Minshall","year":"2024","journal-title":"Brain Sci"},{"key":"10.1016\/j.physbeh.2026.115539_bib0030","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.bbr.2019.02.005","article-title":"Coping with the forced swim stressor: Current state-of-the-art","volume":"364","author":"Molendijk","year":"2019","journal-title":"Behav Brain Res"},{"issue":"5","key":"10.1016\/j.physbeh.2026.115539_bib0031","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1111\/j.1601-1848.2004.00076.x","article-title":"Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice","volume":"3","author":"Moy","year":"2004","journal-title":"Genes Brain Behav"},{"key":"10.1016\/j.physbeh.2026.115539_bib0032","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1016\/j.biopha.2018.05.086","article-title":"Neurobiology and consequences of social isolation stress in animal model: a comprehensive review","volume":"105","author":"Mumtaz","year":"2018","journal-title":"Biomed Pharmacother"},{"issue":"1","key":"10.1016\/j.physbeh.2026.115539_bib0033","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-020-75616-2","article-title":"Evaluation of NDEL1 oligopeptidase activity in blood and brain in an animal model of schizophrenia: effects of psychostimulants and antipsychotics","volume":"10","author":"Nani","year":"2020","journal-title":"Sci Rep"},{"issue":"11","key":"10.1016\/j.physbeh.2026.115539_bib0034","doi-asserted-by":"crossref","first-page":"1488","DOI":"10.1038\/mp.2016.154","article-title":"DISC1 a key molecular lead in psychiatry and neurodevelopment: No-More Disrupted-in-Schizophrenia 1","volume":"21","author":"Niwa","year":"2016","journal-title":"Mol Psychiatry"},{"issue":"3","key":"10.1016\/j.physbeh.2026.115539_bib0035","doi-asserted-by":"crossref","first-page":"4888","DOI":"10.1111\/ejn.15345","article-title":"Social isolation of adolescent male rats increases anxiety and K+ -induced dopamine release in the nucleus accumbens: Role of CRF-R1","volume":"54","author":"Novoa","year":"2021","journal-title":"Eur J Neurosci"},{"issue":"4","key":"10.1016\/j.physbeh.2026.115539_bib0036","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.3390\/biomedicines11041209","article-title":"Genome-environment interactions and psychiatric disorders","volume":"11","author":"Peedicayil","year":"2023","journal-title":"Biomedicines"},{"issue":"4","key":"10.1016\/j.physbeh.2026.115539_bib0037","doi-asserted-by":"crossref","first-page":"397","DOI":"10.31887\/DCNS.2019.21.4\/ebinder","article-title":"Epigenetics and depression","volume":"21","author":"Penner-Goeke","year":"2019","journal-title":"Dialogues Clin Neurosci"},{"issue":"2","key":"10.1016\/j.physbeh.2026.115539_bib0038","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1037\/0735-7044.106.2.274","article-title":"Differential contribution of amygdala and hippocampus to cued and contextual fear conditioning","volume":"106","author":"Phillips","year":"1992","journal-title":"Behav Neurosci"},{"issue":"11","key":"10.1016\/j.physbeh.2026.115539_bib0039","doi-asserted-by":"crossref","first-page":"1383","DOI":"10.1007\/s00702-019-02084-y","article-title":"Animal models of major depression: drawbacks and challenges","volume":"126","author":"Planchez","year":"2019","journal-title":"J Neural Transm (Vienna)"},{"issue":"1-3","key":"10.1016\/j.physbeh.2026.115539_bib0040","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/S0014-2999(03)01272-X","article-title":"The open field as a paradigm to measure the effects of drugs on anxiety-like behaviors: a review","volume":"463","author":"Prut","year":"2003","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.physbeh.2026.115539_bib0041","series-title":"R: A language and environment for statistical computing [computer program]","year":"2024"},{"issue":"10","key":"10.1016\/j.physbeh.2026.115539_bib0042","doi-asserted-by":"crossref","DOI":"10.1038\/tp.2016.205","article-title":"Emergence of social behavior deficit, blunted corticolimbic activity and adult depression\u2011like behavior in a rodent model of maternal maltreatment","volume":"6","author":"Rinc\u00f3n\u2011Cort\u00e9s","year":"2016","journal-title":"Transl Psychiatry"},{"key":"10.1016\/j.physbeh.2026.115539_bib0043","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1016\/j.neubiorev.2019.11.024","article-title":"Neuropeptides and oligopeptidases in schizophrenia","volume":"108","author":"Rodr\u00edguez","year":"2020","journal-title":"Neurosci Biobehav Rev"},{"key":"10.1016\/j.physbeh.2026.115539_bib0044","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.brainresbull.2019.02.005","article-title":"Cumulative multiple early life hits\u2014 a potent threat leading to neurological disorders","volume":"147","author":"Sarkar","year":"2019","journal-title":"Brain Res Bull"},{"key":"10.1016\/j.physbeh.2026.115539_bib0045","series-title":"New statistics for design researchers: a Bayesian workflow in Tidy R","author":"Schmettow","year":"2021"},{"issue":"2","key":"10.1016\/j.physbeh.2026.115539_bib0046","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1007\/s00702-022-02567-5","article-title":"Neurodevelopmental disturbances in schizophrenia: evidence from genetic and environmental factors","volume":"130","author":"Schmitt","year":"2023","journal-title":"J Neural Transm (Vienna)"},{"issue":"6","key":"10.1016\/j.physbeh.2026.115539_bib0047","doi-asserted-by":"crossref","first-page":"848","DOI":"10.3390\/brainsci13060848","article-title":"Investigating the robustness of a rodent \"double hit\" (post-weaning social isolation and NMDA receptor antagonist) model as an animal model for schizophrenia: a systematic review","volume":"13","author":"Shangase","year":"2023","journal-title":"Brain Sci"},{"key":"10.1016\/j.physbeh.2026.115539_bib0048","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.neuroscience.2015.12.061","article-title":"Utility and validity of DISC1 mouse models in biological psychiatry","volume":"321","author":"Tomoda","year":"2016","journal-title":"Neuroscience"},{"issue":"11","key":"10.1016\/j.physbeh.2026.115539_bib0049","doi-asserted-by":"crossref","first-page":"1561","DOI":"10.1038\/mp.2015.194","article-title":"Misassembly of full-length Disrupted-in-Schizophrenia 1 protein is linked to altered dopamine homeostasis and behavioral deficits","volume":"21","author":"Trossbach","year":"2016","journal-title":"Mol Psychiatry"},{"issue":"1","key":"10.1016\/j.physbeh.2026.115539_bib0050","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/s00127-013-0801-0","article-title":"Gene-environment interactions in common mental disorders: an update and strategy for a genome-wide search","volume":"49","author":"Uher","year":"2014","journal-title":"Soc Psychiatry Psychiatr Epidemiol"},{"key":"10.1016\/j.physbeh.2026.115539_bib0051","doi-asserted-by":"crossref","first-page":"66","DOI":"10.3389\/fnbeh.2019.00066","article-title":"Long-term behavioral effects of post-weaning social isolation in males and females","volume":"13","author":"Walker","year":"2019","journal-title":"Front Behav Neurosci"},{"key":"10.1016\/j.physbeh.2026.115539_bib0052","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.pbb.2019.02.005","article-title":"Anxiogenic-like behavior and deficient attention\/working memory in rats expressing the human DISC1 gene","volume":"179","author":"Wang","year":"2019","journal-title":"Pharmacol Biochem Behav"},{"issue":"1","key":"10.1016\/j.physbeh.2026.115539_bib0053","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1038\/s41380-022-01835-w","article-title":"Social isolation and the brain: effects and mechanisms","volume":"28","author":"Xiong","year":"2023","journal-title":"Mol Psychiatry"},{"key":"10.1016\/j.physbeh.2026.115539_bib0054","doi-asserted-by":"crossref","DOI":"10.1016\/j.pbb.2025.174116","article-title":"Challenges in cross-test comparison of anxiety-related outcomes in rodents: A network meta-analysis","volume":"257","author":"Y\u0131ld\u0131r\u0131m","year":"2025","journal-title":"Pharmacol Biochem Behav"}],"container-title":["Physiology &amp; Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0031938426003227?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0031938426003227?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T07:04:19Z","timestamp":1792739059000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0031938426003227"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":54,"alternative-id":["S0031938426003227"],"URL":"https:\/\/doi.org\/10.1016\/j.physbeh.2026.115539","relation":{},"ISSN":["0031-9384"],"issn-type":[{"value":"0031-9384","type":"print"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Gene-Environment Interaction in Transgenic Rats overexpressing human DISC1: Effects of Early Social Isolation on Behavioral Domains","name":"articletitle","label":"Article Title"},{"value":"Physiology & Behavior","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.physbeh.2026.115539","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"115539"}}