{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T14:39:26Z","timestamp":1787063966717,"version":"build-2736575974"},"reference-count":48,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.com.au","clinicalkey.es","clinicalkey.com","physiotherapyjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Physiotherapy"],"published-print":{"date-parts":[[2024,12]]},"DOI":"10.1016\/j.physio.2024.101417","type":"journal-article","created":{"date-parts":[[2024,8,3]],"date-time":"2024-08-03T11:34:33Z","timestamp":1722684873000},"page":"101417","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"special_numbering":"C","title":["Predictive factors and dose\u2013response effect of rehabilitation for upper limb induced recovery after stroke: systematic review with proportional meta-analyses"],"prefix":"10.1016","volume":"125","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8838-0399","authenticated-orcid":false,"given":"Silvia","family":"Salvalaggio","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3770-0011","authenticated-orcid":false,"given":"Silvia","family":"Gianola","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martina","family":"And\u00f2","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8662-9253","authenticated-orcid":false,"given":"Luisa","family":"Cacciante","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Greta","family":"Castellini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8460-6752","authenticated-orcid":false,"given":"Alex","family":"Lando","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gianluca","family":"Ossola","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4622-6393","authenticated-orcid":false,"given":"Giorgia","family":"Pregnolato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebastian","family":"Rutkowski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Vedovato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiara","family":"Zandon\u00e0","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1609-8060","authenticated-orcid":false,"given":"Andrea","family":"Turolla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.physio.2024.101417_bib1","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1055\/s-0038-1649503","article-title":"Global burden of stroke","volume":"38","author":"Katan","year":"2018","journal-title":"Semin Neurol"},{"key":"10.1016\/j.physio.2024.101417_bib2","doi-asserted-by":"crossref","first-page":"190","DOI":"10.3390\/healthcare10020190","article-title":"Rehabilitation of upper limb motor impairment in stroke: a narrative review on the prevalence, risk factors, and economic statistics of stroke and state of the art therapies","volume":"10","author":"Anwer","year":"2022","journal-title":"Healthcare"},{"key":"10.1016\/j.physio.2024.101417_bib3","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1186\/s13643-019-1093-6","article-title":"A systematic review protocol of timing, efficacy and cost effectiveness of upper limb therapy for motor recovery post-stroke","volume":"8","author":"Hayward","year":"2019","journal-title":"Syst Rev"},{"key":"10.1016\/j.physio.2024.101417_bib4","unstructured":"World Stroke Organisation. Global stroke 2022. Available at: \u3008https:\/\/www.world-stroke.org\/assets\/downloads\/WSO_Global_Stroke_Fact_Sheet.pdf\u3009."},{"key":"10.1016\/j.physio.2024.101417_bib5","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1001\/jamainternmed.2019.0302","article-title":"Prognosis reconsidered in light of ancient insights \u2013 from hippocrates to modern medicine","volume":"179","author":"Thomas","year":"2019","journal-title":"JAMA Intern Med"},{"key":"10.1016\/j.physio.2024.101417_bib6","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1080\/10749357.2020.1783915","article-title":"Knowledge and application of upper limb prediction models and attitude toward prognosis among physiotherapists and occupational therapists in the clinical stroke setting","volume":"28","author":"Kiaer","year":"2021","journal-title":"Top Stroke Rehabil"},{"key":"10.1016\/j.physio.2024.101417_bib7","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1177\/0269215511420305","article-title":"Predictors of upper limb recovery after stroke: a systematic review and meta-analysis","volume":"26","author":"Coupar","year":"2012","journal-title":"Clin Rehabil"},{"key":"10.1016\/j.physio.2024.101417_bib8","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1002\/acn3.488","article-title":"PREP2: a biomarker-based algorithm for predicting upper limb function after stroke","volume":"4","author":"Stinear","year":"2017","journal-title":"Ann Clin Transl Neurol"},{"key":"10.1016\/j.physio.2024.101417_bib9","doi-asserted-by":"crossref","first-page":"1371","DOI":"10.3389\/fneur.2019.01371","article-title":"Easily conducted tests during the first week post-stroke can aid the prediction of arm functioning at 6 months","volume":"10","author":"Ghaziani","year":"2019","journal-title":"Front Neurol"},{"key":"10.1016\/j.physio.2024.101417_bib10","doi-asserted-by":"crossref","DOI":"10.3389\/fnagi.2023.1205063","article-title":"Prediction of rehabilitation induced motor recovery after stroke using a multi-dimensional and multi-modal approach","volume":"15","author":"Salvalaggio","year":"2023","journal-title":"Front Aging Neurosci"},{"key":"10.1016\/j.physio.2024.101417_bib11","doi-asserted-by":"crossref","first-page":"335","DOI":"10.3390\/healthcare11030335","article-title":"Clinical predictors for upper limb recovery after stroke rehabilitation: retrospective cohort study","volume":"11","author":"Salvalaggio","year":"2023","journal-title":"Healthcare"},{"key":"10.1016\/j.physio.2024.101417_bib12","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1016\/j.molonc.2007.12.001","article-title":"Prognostic factors versus predictive factors: examples from a clinical trial of erlotinib","volume":"1","author":"Clark","year":"2008","journal-title":"Mol Oncol"},{"key":"10.1016\/j.physio.2024.101417_bib13","doi-asserted-by":"crossref","first-page":"2348","DOI":"10.1161\/01.STR.0000238594.91938.1e","article-title":"Impact of time on improvement of outcome after stroke","volume":"37","author":"Kwakkel","year":"2006","journal-title":"Stroke"},{"key":"10.1016\/j.physio.2024.101417_bib14","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1177\/1545968319846120","article-title":"Long-dose intensive therapy is necessary for strong, clinically significant, upper limb functional gains and retained gains in severe\/moderate chronic stroke","volume":"33","author":"Daly","year":"2019","journal-title":"Neurorehabil Neural Repair"},{"key":"10.1016\/j.physio.2024.101417_bib15","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1136\/jnnp-2018-319954","article-title":"Intensive upper limb neurorehabilitation in chronic stroke: outcomes from the Queen Square programme","volume":"90","author":"Ward","year":"2019","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.physio.2024.101417_bib16","series-title":"Broken movement: the neurobiology of motor recovery after stroke","author":"Krakauer","year":"2017"},{"issue":"Suppl.","key":"10.1016\/j.physio.2024.101417_bib17","doi-asserted-by":"crossref","first-page":"6S","DOI":"10.1177\/1545968311410940","article-title":"Neurological principles and rehabilitation of action disorders: computation, anatomy, and physiology (CAP) model","volume":"25","author":"Frey","year":"2011","journal-title":"Neurorehabil Neural Repair"},{"issue":"Suppl.","key":"10.1016\/j.physio.2024.101417_bib18","doi-asserted-by":"crossref","first-page":"21S","DOI":"10.1177\/1545968311410941","article-title":"Neurological principles and rehabilitation of action disorders: common clinical deficits","volume":"25","author":"Sathian","year":"2011","journal-title":"Neurorehabil Neural Repair"},{"issue":"Suppl.","key":"10.1016\/j.physio.2024.101417_bib19","doi-asserted-by":"crossref","first-page":"33S","DOI":"10.1177\/1545968311410942","article-title":"Neurological principles and rehabilitation of action disorders: rehabilitation interventions","volume":"25","author":"Pomeroy","year":"2011","journal-title":"Neurorehabil Neural Repair"},{"key":"10.1016\/j.physio.2024.101417_bib20","article-title":"Interventions for improving upper limb function after stroke","volume":"11","author":"Pollock","year":"2014","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.physio.2024.101417_bib21","doi-asserted-by":"crossref","first-page":"2008","DOI":"10.1001\/jama.283.15.2008","article-title":"Meta-analysis of observational studies in epidemiology: a proposal for reporting. Meta-analysis Of Observational Studies in Epidemiology (MOOSE) group","volume":"283","author":"Stroup","year":"2000","journal-title":"JAMA"},{"key":"10.1016\/j.physio.2024.101417_bib22","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1001380","article-title":"Prognosis Research Strategy (PROGRESS) 2: prognostic factor research","volume":"10","author":"Riley","year":"2013","journal-title":"PLoS Med"},{"key":"10.1016\/j.physio.2024.101417_bib23","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1186\/s12874-020-01050-7","article-title":"A conceptual framework for prognostic research","volume":"20","author":"Kent","year":"2020","journal-title":"BMC Med Res Methodol"},{"key":"10.1016\/j.physio.2024.101417_bib24","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1186\/s12874-022-01631-8","article-title":"Abstract screening using the automated tool Rayyan: results of effectiveness in three diagnostic test accuracy systematic reviews","volume":"22","author":"Valizadeh","year":"2022","journal-title":"BMC Med Res Methodol"},{"key":"10.1016\/j.physio.2024.101417_bib25","doi-asserted-by":"crossref","first-page":"875","DOI":"10.3389\/fneur.2020.00875","article-title":"Consensus-based core set of outcome measures for clinical motor rehabilitation after stroke \u2013 a Delphi study","volume":"11","author":"Pohl","year":"2020","journal-title":"Front Neurol"},{"key":"10.1016\/j.physio.2024.101417_bib26","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1186\/s12883-015-0292-6","article-title":"An overview of systematic reviews on upper extremity outcome measures after stroke","volume":"15","author":"Alt Murphy","year":"2015","journal-title":"BMC Neurol"},{"key":"10.1016\/j.physio.2024.101417_bib27","doi-asserted-by":"crossref","first-page":"13","DOI":"10.2340\/1650197771331","article-title":"The post-stroke hemiplegic patient. 1. A method for evaluation of physical performance","volume":"7","author":"Fugl-Meyer","year":"1975","journal-title":"Scand J Rehabil Med"},{"key":"10.1016\/j.physio.2024.101417_bib28","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2012-001978","article-title":"Quality of descriptions of treatments: a review of published randomised controlled trials","volume":"2","author":"Schroter","year":"2012","journal-title":"BMJ Open"},{"key":"10.1016\/j.physio.2024.101417_bib29","doi-asserted-by":"crossref","first-page":"g1687","DOI":"10.1136\/bmj.g1687","article-title":"Better reporting of interventions: template for intervention description and replication (TIDieR) checklist and guide","volume":"348","author":"Hoffmann","year":"2014","journal-title":"BMJ"},{"key":"10.1016\/j.physio.2024.101417_bib30","unstructured":"Wells G, Shea B, O\u2019Connell D, Peterson J, Welch V, Losos M, et al. The Newcastle\u2013Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta-analyses; 2013."},{"key":"10.1016\/j.physio.2024.101417_bib31","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1002\/jrsm.1411","article-title":"Risk-of-bias VISualization (robvis): an R package and Shiny web app for visualizing risk-of-bias assessments","volume":"12","author":"McGuinness","year":"2021","journal-title":"Res Synth Methods"},{"key":"10.1016\/j.physio.2024.101417_bib32","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1016\/j.ijnurstu.2013.09.014","article-title":"Power, effects, confidence, and significance: an investigation of statistical practices in nursing research","volume":"51","author":"Gaskin","year":"2014","journal-title":"Int J Nurs Stud"},{"key":"10.1016\/j.physio.2024.101417_bib33","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1136\/bmj.327.7414.557","article-title":"Measuring inconsistency in meta-analyses","volume":"327","author":"Higgins","year":"2003","journal-title":"BMJ"},{"key":"10.1016\/j.physio.2024.101417_bib34","series-title":"RStudio: integrated development environment for R","author":"Team","year":"2015"},{"key":"10.1016\/j.physio.2024.101417_bib35","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1186\/2049-3258-72-39","article-title":"Metaprop: a Stata command to perform meta-analysis of binomial data","volume":"72","author":"Nyaga","year":"2014","journal-title":"Arch Public Health"},{"key":"10.1016\/j.physio.2024.101417_bib36","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1177\/1536867X0800800102","article-title":"METAN: fixed- and random-effects meta-analysis","volume":"8","author":"Harris","year":"2008","journal-title":"Stata J"},{"key":"10.1016\/j.physio.2024.101417_bib37","first-page":"747","article-title":"Factors influencing the response to high-frequency repetitive transcranial magnetic stimulation in patients with subacute stroke","volume":"34","author":"Chang","year":"2016","journal-title":"Restor Neurol Neurosci"},{"key":"10.1016\/j.physio.2024.101417_bib38","first-page":"189","article-title":"Efficacy of EMG-triggered electrical arm stimulation in chronic hemiparetic stroke patients","volume":"27","author":"von Lewinski","year":"2009","journal-title":"Restor Neurol Neurosci"},{"key":"10.1016\/j.physio.2024.101417_bib39","doi-asserted-by":"crossref","first-page":"2525","DOI":"10.1109\/TNSRE.2020.3027955","article-title":"Interhemispheric functional reorganization and its structural base after BCI-guided upper-limb training in chronic stroke","volume":"28","author":"Yuan","year":"2020","journal-title":"IEEE Trans Neural Syst Rehabil Eng"},{"key":"10.1016\/j.physio.2024.101417_bib40","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1002\/ana.24309","article-title":"Neural function, injury, and stroke subtype predict treatment gains after stroke","volume":"77","author":"Burke Quinlan","year":"2015","journal-title":"Ann Neurol"},{"key":"10.1016\/j.physio.2024.101417_bib41","doi-asserted-by":"crossref","first-page":"e1098","DOI":"10.1212\/WNL.0000000000007041","article-title":"Somatosensory system integrity explains differences in treatment response after stroke","volume":"92","author":"Ingemanson","year":"2019","journal-title":"Neurology"},{"key":"10.1016\/j.physio.2024.101417_bib42","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1177\/15459683221095171","article-title":"Baseline predictors of response to repetitive task practice in chronic stroke","volume":"36","author":"Dimyan","year":"2022","journal-title":"Neurorehabil Neural Repair"},{"key":"10.1016\/j.physio.2024.101417_bib43","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1177\/1545968317740634","article-title":"Longitudinal structural and functional differences between proportional and poor motor recovery after stroke","volume":"31","author":"Guggisberg","year":"2017","journal-title":"Neurorehabil Neural Repair"},{"key":"10.1016\/j.physio.2024.101417_bib44","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1177\/1545968317732680","article-title":"Biomarkers of stroke recovery: consensus-based core recommendations from the Stroke Recovery and Rehabilitation Roundtable","volume":"31","author":"Boyd","year":"2017","journal-title":"Neurorehabil Neural Repair"},{"key":"10.1016\/j.physio.2024.101417_bib45","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.jphys.2020.04.001","article-title":"Repetitions and dose in stroke rehabilitation","volume":"66","author":"Dorsch","year":"2020","journal-title":"J Physiother"},{"key":"10.1016\/j.physio.2024.101417_bib46","doi-asserted-by":"crossref","DOI":"10.1093\/ptj\/pzad060","article-title":"Is clinical research as helpful to clinicians as it could be?","volume":"103","author":"Turolla","year":"2023","journal-title":"Phys Ther"},{"key":"10.1016\/j.physio.2024.101417_bib47","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1001381","article-title":"Prognosis Research Strategy (PROGRESS) 3: prognostic model research","volume":"10","author":"Steyerberg","year":"2013","journal-title":"PLoS Med"},{"key":"10.1016\/j.physio.2024.101417_bib48","doi-asserted-by":"crossref","first-page":"b375","DOI":"10.1136\/bmj.b375","article-title":"Prognosis and prognostic research: what, why, and how?","volume":"338","author":"Moons","year":"2009","journal-title":"BMJ"}],"container-title":["Physiotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0031940624004267?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0031940624004267?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,2,4]],"date-time":"2025-02-04T09:04:07Z","timestamp":1738659847000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0031940624004267"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12]]},"references-count":48,"alternative-id":["S0031940624004267"],"URL":"https:\/\/doi.org\/10.1016\/j.physio.2024.101417","relation":{},"ISSN":["0031-9406"],"issn-type":[{"value":"0031-9406","type":"print"}],"subject":[],"published":{"date-parts":[[2024,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Predictive factors and dose\u2013response effect of rehabilitation for upper limb induced recovery after stroke: systematic review with proportional meta-analyses","name":"articletitle","label":"Article Title"},{"value":"Physiotherapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.physio.2024.101417","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Chartered Society of Physiotherapy. Published by Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"101417"}}