{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T14:09:02Z","timestamp":1791900542772,"version":"4.3.4"},"reference-count":28,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2008,2,1]],"date-time":"2008-02-01T00:00:00Z","timestamp":1201824000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Phytochemistry"],"published-print":{"date-parts":[[2008,2]]},"DOI":"10.1016\/j.phytochem.2007.09.023","type":"journal-article","created":{"date-parts":[[2007,11,8]],"date-time":"2007-11-08T12:35:58Z","timestamp":1194525358000},"page":"754-758","source":"Crossref","is-referenced-by-count":80,"title":["Xanthones with quinone reductase-inducing activity from the fruits of Garcinia mangostana (Mangosteen)"],"prefix":"10.1016","volume":"69","author":[{"given":"Young-Won","family":"Chin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyun-Ah","family":"Jung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heebyung","family":"Chai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William J.","family":"Keller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. Douglas","family":"Kinghorn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.phytochem.2007.09.023_bib1","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1248\/bpb.25.247","article-title":"Studies on cancer chemoprevention by traditional folk medicines. XXV. Inhibitory effect of isoliquiritigenin on azoxymethane-induced murine colon aberrant crypt focus formation and carcinogenesis","volume":"25","author":"Baba","year":"2002","journal-title":"Biol. Pharm. Bull."},{"key":"10.1016\/j.phytochem.2007.09.023_bib2","doi-asserted-by":"crossref","first-page":"4691","DOI":"10.1021\/jf0703553","article-title":"Anti-oxidant constituents of the roots and stolons of licorice (Glycyrrhiza glabra)","volume":"55","author":"Chin","year":"2007","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.phytochem.2007.09.023_bib3","series-title":"Thai Medicinal Plants Recommended for Primary Health Care System","author":"Farnsworth","year":"1992"},{"key":"10.1016\/j.phytochem.2007.09.023_bib4","unstructured":"Garrity, A.R., Morton, G.A., Morton, J.C., 2004. Nutraceutical mangosteen composition. US Patent 6730333 B1 20040504, 7 pp."},{"key":"10.1016\/j.phytochem.2007.09.023_bib5","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1021\/np970165u","article-title":"Evaluation of the antifungal activity of natural xanthones from Garcinia mangostana and their synthetic derivatives","volume":"60","author":"Gopalakrishnan","year":"1997","journal-title":"J. Nat. Prod."},{"key":"10.1016\/j.phytochem.2007.09.023_bib6","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0076-6879(90)86093-B","article-title":"Role of free radicals and catalytic metal ions in human disease: an overview","volume":"186","author":"Halliwell","year":"1990","journal-title":"Method. Enzymol."},{"key":"10.1016\/j.phytochem.2007.09.023_bib7","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1055\/s-2006-961016","article-title":"Structures of four new isoprenylated xanthones, cudraxanthones H, I, J, and K","volume":"56","author":"Hano","year":"1990","journal-title":"Planta Med."},{"key":"10.1016\/j.phytochem.2007.09.023_bib8","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1021\/np020522n","article-title":"Potential cancer chemopreventive constituents of the seeds of Dipteryx odorata (Tonka Bean)","volume":"66","author":"Jang","year":"2003","journal-title":"J. Nat. Prod."},{"key":"10.1016\/j.phytochem.2007.09.023_bib9","doi-asserted-by":"crossref","first-page":"1270","DOI":"10.1016\/j.jpba.2006.10.018","article-title":"Quantitative and qualitative determination of six xanthones in Garcinia mangostana L. by LC-PDA and LC-ESI-MS","volume":"43","author":"Ji","year":"2007","journal-title":"J. Pharm. Biomed. Anal."},{"key":"10.1016\/j.phytochem.2007.09.023_bib10","doi-asserted-by":"crossref","first-page":"2077","DOI":"10.1021\/jf052649z","article-title":"Antioxidant xanthones from the pericarp of Garcinia mangostana (mangosteen)","volume":"54","author":"Jung","year":"2006","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.phytochem.2007.09.023_bib11","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1021\/np50051a021","article-title":"Chemical constituents of Garcinia mangostana","volume":"50","author":"Mahabusarakam","year":"1987","journal-title":"J. Nat. Prod."},{"key":"10.1016\/j.phytochem.2007.09.023_bib12","doi-asserted-by":"crossref","first-page":"912","DOI":"10.1055\/s-2006-947190","article-title":"Prenylated xanthones as potential antiplasmodial substances","volume":"72","author":"Mahabusarakam","year":"2006","journal-title":"Planta Med."},{"key":"10.1016\/j.phytochem.2007.09.023_bib13","doi-asserted-by":"crossref","first-page":"6064","DOI":"10.1016\/j.bmc.2005.06.065","article-title":"Xanthones induce cell-cycle arrest and apoptosis in human colon cancer DLD-1 cells","volume":"13","author":"Matsumoto","year":"2005","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.phytochem.2007.09.023_bib14","first-page":"433","article-title":"Inhibitory effects of crude \u03b1-mangostin, a xanthone derivative, on two different categories of colon preneoplastic lesions induced by 1,2-dimethylhydrazine in the rat","volume":"5","author":"Nabandith","year":"2004","journal-title":"Asian Pac. J. Cancer Prev."},{"key":"10.1016\/j.phytochem.2007.09.023_bib15","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1124\/mol.104.002626","article-title":"\u03b3-Mangostin inhibits inhibitor-\u03baB kinase activity and decreases lipopolysaccharide-induced cyclooxygenase-2 gene expression in C6 rat glioma cells","volume":"66","author":"Nakatani","year":"2004","journal-title":"Mol. Pharmacol."},{"key":"10.1016\/j.phytochem.2007.09.023_bib16","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/S0031-9422(02)00142-5","article-title":"Xanthones from the heartwood of Garcinia mangostana","volume":"60","author":"Nilar","year":"2002","journal-title":"Phytochemistry"},{"key":"10.1016\/j.phytochem.2007.09.023_bib17","unstructured":"Nutrition Business Journal, 2006. NBJ\u2019s Supplement Business Report 2006: an analysis of markets, trends, competition and strategy in the U.S. dietary supplement industry. Penton Media Inc: San Diego, pp. 186\u2013200."},{"key":"10.1016\/j.phytochem.2007.09.023_bib18","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1016\/S0031-9422(00)00303-4","article-title":"Tetraoxygenated naturally occurring xanthones","volume":"55","author":"Peres","year":"2000","journal-title":"Phytochemistry"},{"key":"10.1016\/j.phytochem.2007.09.023_bib19","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1016\/0003-2697(88)90292-8","article-title":"Direct measurement of NAD(P)H:quinone reductase from cells cultured in microtiter wells: a screening assay for anticarcinogenic enzyme inducers","volume":"169","author":"Prochaska","year":"1988","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.phytochem.2007.09.023_bib20","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/j.phymed.2003.09.012","article-title":"Antibacterial activity of \u03b1-mangostin against vancomycin resistant Enterococci (VRE) and synergism with antibiotics","volume":"12","author":"Sakagami","year":"2005","journal-title":"Phytomedicine"},{"key":"10.1016\/j.phytochem.2007.09.023_bib21","doi-asserted-by":"crossref","first-page":"1747","DOI":"10.1016\/0031-9422(82)85052-8","article-title":"The structure of garcinones A, B, and C: three new xanthones from Garcinia mangostana","volume":"21","author":"Sen","year":"1982","journal-title":"Phytochemistry"},{"key":"10.1016\/j.phytochem.2007.09.023_bib22","first-page":"1332","article-title":"Prevention of chemical carcinogenesis by vitamin A and its synthetic analogs (retinoids)","volume":"35","author":"Sporn","year":"1976","journal-title":"Fed. Proc."},{"key":"10.1016\/j.phytochem.2007.09.023_bib23","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/S0031-9422(03)00112-2","article-title":"Activity-guided isolation of the chemical constituents of Muntingia calabura using a quinone reductase induction assay","volume":"63","author":"Su","year":"2003","journal-title":"Phytochemistry"},{"key":"10.1016\/j.phytochem.2007.09.023_bib24","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1248\/cpb.51.857","article-title":"Antimycobacterial activity of prenylated xanthones from the fruits of Garcinia mangostana","volume":"51","author":"Suksamarn","year":"2003","journal-title":"Chem. Pharm. Bull."},{"key":"10.1016\/j.phytochem.2007.09.023_bib25","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1248\/cpb.54.301","article-title":"Cytotoxic prenylated xanthones from the young fruit of Garcinia mangostana","volume":"54","author":"Suksamrarn","year":"2006","journal-title":"Chem. Pharm. Bull."},{"key":"10.1016\/j.phytochem.2007.09.023_bib26","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/0378-4274(95)03553-2","article-title":"Chemoprotection against cancer by phase 2 enzyme induction","volume":"82\u201383","author":"Talalay","year":"1995","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.phytochem.2007.09.023_bib27","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.foodchem.2006.11.018","article-title":"Phenolics from hull of Garcinia mangostana fruit and their antioxidant activities","volume":"104","author":"Yu","year":"2007","journal-title":"Food Chem."},{"key":"10.1016\/j.phytochem.2007.09.023_bib28","doi-asserted-by":"crossref","first-page":"5884","DOI":"10.1021\/jf020496z","article-title":"Peroxynitrite scavenging activity of sinapic acid (3,5-dimethoxy-4-hydroxycinnamic acid) isolated from Brassica juncea","volume":"50","author":"Zou","year":"2002","journal-title":"J. Agric. Food Chem."}],"container-title":["Phytochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0031942207005961?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0031942207005961?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,1,3]],"date-time":"2019-01-03T02:56:34Z","timestamp":1546484194000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0031942207005961"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,2]]},"references-count":28,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2008,2]]}},"alternative-id":["S0031942207005961"],"URL":"https:\/\/doi.org\/10.1016\/j.phytochem.2007.09.023","relation":{},"ISSN":["0031-9422"],"issn-type":[{"value":"0031-9422","type":"print"}],"subject":[],"published":{"date-parts":[[2008,2]]}}}