{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,18]],"date-time":"2026-04-18T10:31:03Z","timestamp":1776508263654,"version":"3.51.2"},"reference-count":18,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,11,1]],"date-time":"2017-11-01T00:00:00Z","timestamp":1509494400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Phytochemistry"],"published-print":{"date-parts":[[2017,11]]},"DOI":"10.1016\/j.phytochem.2017.08.010","type":"journal-article","created":{"date-parts":[[2017,8,24]],"date-time":"2017-08-24T00:02:55Z","timestamp":1503532975000},"page":"194-198","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"special_numbering":"C","title":["Antiproliferative metabolites from the Northern African endemic plant Daucus virgatus (Apiaceae)"],"prefix":"10.1016","volume":"143","author":[{"given":"Al\u00ec","family":"Snene","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carmina","family":"Sirignano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniela","family":"Rigano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carmen","family":"Formisano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ridha","family":"El Mokni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Ercolano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hatem","family":"Dhaouadi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angela","family":"Ianaro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saoussen","family":"Hammami","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Orazio","family":"Taglialatela-Scafati","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.phytochem.2017.08.010_bib1","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1039\/p19860001363","article-title":"Structural and conformational studies of sesquiterpenoid esters from Laserpitium halleri Crantz subsp. halleri","author":"Appendino","year":"1986","journal-title":"J.\u00a0Chem. Soc. Perkin Trans. I"},{"key":"10.1016\/j.phytochem.2017.08.010_bib2","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1016\/0031-9422(93)85296-4","article-title":"Sesquiterpene lactones from Laserpitium gallicum","volume":"33","author":"Appendino","year":"1993","journal-title":"Phytochemistry"},{"key":"10.1016\/j.phytochem.2017.08.010_bib3","doi-asserted-by":"crossref","first-page":"65","DOI":"10.3389\/fphar.2017.00065","article-title":"The hydrogen sulfide releasing molecule acetyl deacylasadisulfide inhibits metastatic melanoma","volume":"8","author":"De Cicco","year":"2017","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.phytochem.2017.08.010_bib4","doi-asserted-by":"crossref","first-page":"550","DOI":"10.5897\/JMPR2014.5370","article-title":"Polyphenol derivatives from bioactive butanol phase of the Tunisian narrow-leaved asphodel (Asphodelus tenuifolius Cav., Asphodelaceae)","volume":"8","author":"Faidi","year":"2014","journal-title":"J.\u00a0Med. Plant Res."},{"key":"10.1016\/j.phytochem.2017.08.010_bib5","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.1021\/ol049878b","article-title":"Radical carboxyarylation approach to lignans. Total synthesis of (-)-arctigenin, (-)-matairesinol, and related natural products","volume":"6","author":"Fischer","year":"2004","journal-title":"Org. Lett."},{"key":"10.1016\/j.phytochem.2017.08.010_bib6","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1016\/0003-9861(92)90173-T","article-title":"Catabolism of camphor in tissue cultures and leaf disks of common sage (Salvia officinalis)","volume":"294","author":"Funk","year":"1992","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.phytochem.2017.08.010_bib7","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.1080\/14786419.2012.725401","article-title":"A\u00a0novel methylated sesquiterpene from seagrass Posidonia oceanica (L.) Delile","volume":"27","author":"Hammami","year":"2013","journal-title":"Nat. Prod. Res."},{"key":"10.1016\/j.phytochem.2017.08.010_bib8","doi-asserted-by":"crossref","first-page":"2142","DOI":"10.1080\/14786419.2016.1143828","article-title":"New bioactive labdane diterpenoids from Marrubium aschersonii","volume":"30","author":"Hammami","year":"2016","journal-title":"Nat. Prod. Res."},{"key":"10.1016\/j.phytochem.2017.08.010_bib9","doi-asserted-by":"crossref","first-page":"973","DOI":"10.2174\/1385272003375923","article-title":"The potential of African plants as a source of drugs","volume":"4","author":"Hostettmann","year":"2000","journal-title":"Curr. Org. Chem."},{"key":"10.1016\/j.phytochem.2017.08.010_bib10","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1002\/ptr.3609","article-title":"Antimicrobial antioxidant daucane sesquiterpenes from Ferula hermonis Boiss","volume":"26","author":"Ibraheim","year":"2012","journal-title":"Phytother. Res."},{"key":"10.1016\/j.phytochem.2017.08.010_bib11","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1046\/j.1365-2699.2001.00527.x","article-title":"Plant diversity and endemism in Sub-Saharan tropical Africa","volume":"28","author":"Linder","year":"2001","journal-title":"J.\u00a0Biogeogr."},{"key":"10.1016\/j.phytochem.2017.08.010_bib12","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1016\/0031-9422(95)00862-4","article-title":"Toxicity of 6-methoxymellein and 6-hydroxymellein to the producing carrot cells","volume":"42","author":"Marinelli","year":"1996","journal-title":"Phytochemistry"},{"key":"10.1016\/j.phytochem.2017.08.010_bib13","first-page":"584","article-title":"The structure of vaginatin: a new sesquiterpene from the root extractive of Selinum vaginatum","author":"Mesta","year":"1968","journal-title":"Chem. Commun."},{"key":"10.1016\/j.phytochem.2017.08.010_bib14","doi-asserted-by":"crossref","first-page":"1583","DOI":"10.1080\/14786419.2017.1280490","article-title":"Phytochemical composition and antioxidant activity of medicinal plants collected from the Tunisian flora","volume":"31","author":"Neffati","year":"2017","journal-title":"Nat. Prod. Res."},{"key":"10.1016\/j.phytochem.2017.08.010_bib15","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1016\/0031-9422(82)83177-4","article-title":"Laserine oxide, an epoxide from Guillonea scabra","volume":"21","author":"Pinar","year":"1982","journal-title":"Phytochemistry"},{"key":"10.1016\/j.phytochem.2017.08.010_bib16","doi-asserted-by":"crossref","first-page":"2278","DOI":"10.1002\/cbdv.201300137","article-title":"Variation of the chemical composition and antimicrobial activity of the essential oils of natural populations of Tunisian Daucus carota L. (Apiaceae)","volume":"10","author":"Rokbeni","year":"2013","journal-title":"Chem. Biodiv."},{"key":"10.1016\/j.phytochem.2017.08.010_bib17","doi-asserted-by":"crossref","first-page":"10252","DOI":"10.1021\/jf8023358","article-title":"Reinvestigation of the bitter compounds in carrots (Daucus carota L.) by using a molecular sensory science approach","volume":"56","author":"Scmiech","year":"2008","journal-title":"J.\u00a0Agric. Food Chem."},{"key":"10.1016\/j.phytochem.2017.08.010_bib18","doi-asserted-by":"crossref","first-page":"5036","DOI":"10.1021\/ja01575a056","article-title":"Bitter flavor in carrots. IV. The isolation and identification of 3-methyl-6-methoxy-8-hydroxy-3,4-dihydroisocoumarin from carrots","volume":"79","author":"Sondheimer","year":"1957","journal-title":"J.\u00a0Am. Chem. Soc."}],"container-title":["Phytochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0031942217302856?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0031942217302856?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,12,10]],"date-time":"2019-12-10T03:58:14Z","timestamp":1575950294000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0031942217302856"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,11]]},"references-count":18,"alternative-id":["S0031942217302856"],"URL":"https:\/\/doi.org\/10.1016\/j.phytochem.2017.08.010","relation":{},"ISSN":["0031-9422"],"issn-type":[{"value":"0031-9422","type":"print"}],"subject":[],"published":{"date-parts":[[2017,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Antiproliferative metabolites from the Northern African endemic plant Daucus virgatus (Apiaceae)","name":"articletitle","label":"Article Title"},{"value":"Phytochemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.phytochem.2017.08.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}