{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T05:55:09Z","timestamp":1788242109690,"version":"build-2803163510"},"reference-count":25,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100011636","name":"State Key Laboratory of Bioactive Substance and Function of Natural Medicines","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100011636","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100019018","name":"Chinese Academy of Medical Sciences Initiative for Innovative Medicine","doi-asserted-by":"publisher","award":["2021-I2M-1-027-4"],"award-info":[{"award-number":["2021-I2M-1-027-4"]}],"id":[{"id":"10.13039\/501100019018","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100019018","name":"Chinese Academy of Medical Sciences Initiative for Innovative Medicine","doi-asserted-by":"publisher","award":["2021-I2M-1-028-1"],"award-info":[{"award-number":["2021-I2M-1-028-1"]}],"id":[{"id":"10.13039\/501100019018","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Phytochemistry"],"published-print":{"date-parts":[[2026,3]]},"DOI":"10.1016\/j.phytochem.2025.114725","type":"journal-article","created":{"date-parts":[[2025,11,25]],"date-time":"2025-11-25T00:27:54Z","timestamp":1764030474000},"page":"114725","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Cyclopentanoid monoterpene glycosides from the aerial parts of Paederia foetida L"],"prefix":"10.1016","volume":"243","author":[{"given":"Wan-Qi","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin-Yue","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming-Hui","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guo-Ru","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"De-Quan","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan-Fei","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.phytochem.2025.114725_bib1","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1002\/chir.22138","article-title":"SpecDis: quantifying the comparison of calculated and experimental electronic circular dichroism spectra","volume":"25","author":"Bruhn","year":"2013","journal-title":"Chirality"},{"key":"10.1016\/j.phytochem.2025.114725_bib2","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1021\/np000614h","article-title":"Flavonoid, iridoid, and lignan glycosides from Putoria calabrica","volume":"64","author":"\u00c7alis","year":"2001","journal-title":"J. Nat. Prod."},{"key":"10.1016\/j.phytochem.2025.114725_bib3","doi-asserted-by":"crossref","first-page":"2488","DOI":"10.1002\/hlca.201000129","article-title":"Biologically active iridoids from Hedyotis diffusa","volume":"93","author":"Ding","year":"2010","journal-title":"Helv. Chim. Acta"},{"key":"10.1016\/j.phytochem.2025.114725_bib4","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1021\/np50012a001","article-title":"Iridoids. A review","volume":"43","author":"El-Naggar","year":"1980","journal-title":"J. Nat. Prod."},{"key":"10.1016\/j.phytochem.2025.114725_bib5","series-title":"Gaussian 16","author":"Frisch","year":"2016"},{"key":"10.1016\/j.phytochem.2025.114725_bib6","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.fct.2013.11.022","article-title":"Protective effect of iridoid glycosides from Paederia scandens (lour.) Merr. (Rubiaceae) on uric acid nephropathy rats induced by yeast and potassium oxonate","volume":"64","author":"Hou","year":"2014","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.phytochem.2025.114725_bib7","doi-asserted-by":"crossref","DOI":"10.1016\/j.phytochem.2024.114034","article-title":"Anti-inflammatory monoterpenes from morinda (Morinda officinalis How.)","volume":"220","author":"Jiang","year":"2024","journal-title":"Phytochemistry"},{"key":"10.1016\/j.phytochem.2025.114725_bib8","doi-asserted-by":"crossref","first-page":"1156","DOI":"10.1007\/BF02972979","article-title":"Iridoid glycosides isolated from Oldenlandia diffusa inhibit LDL-oxidation","volume":"28","author":"Kim","year":"2005","journal-title":"Arch Pharm. Res. (Seoul)"},{"key":"10.1016\/j.phytochem.2025.114725_bib9","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1021\/np010479o","article-title":"Sulfur-Containing bis-iridoid glucosides and iridoid glucosides from Saprosma scortechinii","volume":"65","author":"Ling","year":"2002","journal-title":"J. Nat. Prod."},{"key":"10.1016\/j.phytochem.2025.114725_bib10","doi-asserted-by":"crossref","first-page":"3606","DOI":"10.1038\/ncomms4606","article-title":"The seco-iridoid pathway from Catharanthus roseus","volume":"5","author":"Miettinen","year":"2014","journal-title":"Nat. Commun."},{"key":"10.1016\/j.phytochem.2025.114725_bib11","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1055\/s-2006-962773","article-title":"The structural transformation of gardenoside and its related iridoid compounds by acid and \u03b2-Glucosidase","volume":"53","author":"Miyagoshi","year":"2007","journal-title":"Planta Med."},{"key":"10.1016\/j.phytochem.2025.114725_bib12","doi-asserted-by":"crossref","first-page":"2049","DOI":"10.1248\/cpb.39.2049","article-title":"Isolation of 10-O-Acyl iridoid glucosides from a Philippine medicinal plant, Oldenlandia corymbosa L. (Rubiaceae)","volume":"39","author":"Otsuka","year":"1991","journal-title":"Chem. Pharm. Bull."},{"key":"10.1016\/j.phytochem.2025.114725_bib13","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/j.jep.2015.08.032","article-title":"Hepatoprotective activity of total iridoid glycosides isolated from Paederia scandens (Lour.) Merr. var. tomentosa","volume":"174","author":"Peng","year":"2015","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.phytochem.2025.114725_bib14","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/S0031-9422(02)00096-1","article-title":"Iridoid glucosides from roots of Vietnamese Paederia scandens","volume":"60","author":"Quang","year":"2002","journal-title":"Phytochemistry"},{"key":"10.1016\/j.phytochem.2025.114725_bib15","doi-asserted-by":"crossref","first-page":"1312","DOI":"10.1021\/np0780046","article-title":"Iridoids from the green leaves of Eucommia ulmoides","volume":"70","author":"Takamura","year":"2007","journal-title":"J. Nat. Prod."},{"key":"10.1016\/j.phytochem.2025.114725_bib16","doi-asserted-by":"crossref","first-page":"2644","DOI":"10.1248\/cpb.24.2644","article-title":"Studies on monoterpene glucosides and related natural products. 34. Two further new glucosides from the fruit of Gardenia jasminoides Ellis forma grandiflora (Lour.) Makino","volume":"24","author":"Takeda","year":"1976","journal-title":"Chem. Pharm. Bull."},{"key":"10.1016\/j.phytochem.2025.114725_bib17","doi-asserted-by":"crossref","first-page":"1718","DOI":"10.1002\/hlca.200790179","article-title":"Scyphiphorins A and B, two new iridoid glycosides from the stem bark of a Chinese mangrove Scyphiphora hydrophyllacea","volume":"90","author":"Tao","year":"2007","journal-title":"Helv. Chim. Acta"},{"key":"10.1016\/j.phytochem.2025.114725_bib18","first-page":"879","article-title":"A phytochemical, pharmacological and clinical profile of Paederia foetida and P. scandens","volume":"9","author":"Wang","year":"2014","journal-title":"Nat. Prod. Commun."},{"key":"10.1016\/j.phytochem.2025.114725_bib19","first-page":"826","article-title":"Research progress on chemical composition, pharmacological activity of Paederia scandens","volume":"16","author":"Wang","year":"2021","journal-title":"Lour.) Merr. Shijie Zhongyiyao"},{"key":"10.1016\/j.phytochem.2025.114725_bib20","first-page":"596","article-title":"Chemical constituents from barks of Euonymus laxiflorus Champ. ex Benth","volume":"20","author":"Wang","year":"2012","journal-title":"Re Dai Ya Re Dai Zhi Wu Xue Bao"},{"key":"10.1016\/j.phytochem.2025.114725_bib21","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.jep.2018.08.012","article-title":"Protective effects of Paederia scandens extract on rheumatoid arthritis mouse model by modulating gut microbiota","volume":"226","author":"Xiao","year":"2018","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.phytochem.2025.114725_bib22","first-page":"10","article-title":"Studies on chemical constituents and quantitative determination of asperuloside and geniposide from Hedyotis chrysotricha (Palib.) Merr","volume":"39","author":"Yang","year":"2020","journal-title":"Yaoxue Yanjiu"},{"key":"10.1016\/j.phytochem.2025.114725_bib23","doi-asserted-by":"crossref","first-page":"5579","DOI":"10.1016\/j.tet.2015.06.054","article-title":"Cytotoxic iridal-type triterpenoids from Iris tectorum","author":"Zhang","year":"2015","journal-title":"Tetrahedron 71"},{"key":"10.1016\/j.phytochem.2025.114725_bib24","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1021\/np4000747","article-title":"Sesquiterpenes and Alkaloids from the roots of Alangium chinense","volume":"76","author":"Zhang","year":"2013","journal-title":"J. Nat. Prod."},{"key":"10.1016\/j.phytochem.2025.114725_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.phytochem.2022.113316","article-title":"Cyclopentanoid monoterpenes from the whole plant of Rehmannia piasezkii Maxim","volume":"203","author":"Zhou","year":"2022","journal-title":"Phytochemistry"}],"container-title":["Phytochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0031942225003486?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0031942225003486?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T19:42:26Z","timestamp":1785958946000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0031942225003486"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":25,"alternative-id":["S0031942225003486"],"URL":"https:\/\/doi.org\/10.1016\/j.phytochem.2025.114725","relation":{},"ISSN":["0031-9422"],"issn-type":[{"value":"0031-9422","type":"print"}],"subject":[],"published":{"date-parts":[[2026,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cyclopentanoid monoterpene glycosides from the aerial parts of Paederia foetida L","name":"articletitle","label":"Article Title"},{"value":"Phytochemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.phytochem.2025.114725","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"114725"}}