{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T19:35:51Z","timestamp":1780601751319,"version":"3.54.1"},"reference-count":36,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22407030"],"award-info":[{"award-number":["22407030"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22177021"],"award-info":[{"award-number":["22177021"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012434","name":"Middle-aged and Young Teachers' Basic Ability Promotion Project of Guangxi","doi-asserted-by":"publisher","award":["2024KY0064"],"award-info":[{"award-number":["2024KY0064"]}],"id":[{"id":"10.13039\/501100012434","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100019006","name":"State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources","doi-asserted-by":"publisher","award":["CMEMR2023-A01"],"award-info":[{"award-number":["CMEMR2023-A01"]}],"id":[{"id":"10.13039\/501100019006","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Phytochemistry"],"published-print":{"date-parts":[[2026,3]]},"DOI":"10.1016\/j.phytochem.2025.114734","type":"journal-article","created":{"date-parts":[[2025,11,30]],"date-time":"2025-11-30T06:27:10Z","timestamp":1764484030000},"page":"114734","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Structurally diverse sesquiterpenoid glycosides with anti-inflammatory activity from Cissampelopsis spelaeicola"],"prefix":"10.1016","volume":"243","author":[{"given":"Si-Hang","family":"Lin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ning","family":"Diao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9786-7492","authenticated-orcid":false,"given":"Yan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong","family":"Liang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.phytochem.2025.114734_bib1","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1080\/14786410500462843","article-title":"Constituents of Salvia microphylla","volume":"20","author":"Aydo\u01e7mu\u015f","year":"2006","journal-title":"Nat. Prod. Res."},{"key":"10.1016\/j.phytochem.2025.114734_bib2","doi-asserted-by":"crossref","first-page":"10598","DOI":"10.1016\/j.tet.2013.10.047","article-title":"Senedensiscins A\u2212F: six new eudesmane sesquiterpenoid glucosides from Senecio densiserratus","volume":"69","author":"Chen","year":"2013","journal-title":"Tetrahedron"},{"key":"10.1016\/j.phytochem.2025.114734_bib3","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1021\/np8006843","article-title":"T-muurolol sesquiterpenes from the marine Streptomyces sp. M491 and revision of the configuration of previously reported amorphanes","volume":"72","author":"Ding","year":"2009","journal-title":"J. Nat. Prod."},{"key":"10.1016\/j.phytochem.2025.114734_bib4","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1107\/S0021889808042726","article-title":"OLEX2: a complete structure solution, refinement and analysis program","volume":"42","author":"Dolomanov","year":"2009","journal-title":"J. Appl. Crystallogr."},{"key":"10.1016\/j.phytochem.2025.114734_bib5","doi-asserted-by":"crossref","first-page":"1226","DOI":"10.1039\/c3np70047j","article-title":"Natural sesquiterpenoids","volume":"30","author":"Fraga","year":"2013","journal-title":"Nat. Prod. Rep."},{"key":"10.1016\/j.phytochem.2025.114734_bib6","doi-asserted-by":"crossref","first-page":"12526","DOI":"10.1021\/acs.joc.5b02396","article-title":"Beyond DP4: an improved probability for the stereochemical assignment of isomeric compounds using quantum chemical calculations of NMR shifts","volume":"80","author":"Grimblat","year":"2015","journal-title":"J. Org. Chem."},{"key":"10.1016\/j.phytochem.2025.114734_bib7","doi-asserted-by":"crossref","first-page":"3471","DOI":"10.1002\/ps.7527","article-title":"Pitsubcosides A\u2013L, highly esterified eudesmane sesquiterpenoid glycosides with antibacterial activity from Pittosporum subulisepalum and their mechanism","volume":"79","author":"Guan","year":"2023","journal-title":"Pest Manag. Sci."},{"key":"10.1016\/j.phytochem.2025.114734_bib8","doi-asserted-by":"crossref","DOI":"10.1016\/j.phytochem.2025.114456","article-title":"Structurally diverse abietane diterpenoids from the whole plants of Salvia przewalskii Maxim. With anti-inflammatory activity","volume":"235","author":"Guo","year":"2025","journal-title":"Phytochemistry"},{"key":"10.1016\/j.phytochem.2025.114734_bib9","first-page":"36","article-title":"A preliminary study on chemical composition from Yao medicine Cissampelopsis spelaeicola","volume":"29","author":"Huang","year":"2020","journal-title":"Chin. J. Ethnomed. Ethnopharmacy"},{"key":"10.1016\/j.phytochem.2025.114734_bib10","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1107\/S1600576715005580","article-title":"DSR: enhanced modelling and refinement of disordered structures with SHELXL","volume":"48","author":"Kratzert","year":"2015","journal-title":"J. Appl. Crystallogr."},{"key":"10.1016\/j.phytochem.2025.114734_bib11","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1002\/jccs.197600022","article-title":"The structure of cadinane-4\u03b1,9\u03b1-diol-2-ene","volume":"23","author":"Kuo","year":"1976","journal-title":"J. Chin. Chem. Soc."},{"key":"10.1016\/j.phytochem.2025.114734_bib12","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2024.156140","article-title":"A neolignan enantiomer from Piper hancei with anti-neuroinflammatory effect by attenuating NF-\u03baB signaling pathway","volume":"135","author":"Lan","year":"2024","journal-title":"Phytomedicine"},{"key":"10.1016\/j.phytochem.2025.114734_bib13","doi-asserted-by":"crossref","DOI":"10.1016\/j.phytochem.2024.113973","article-title":"Hysterolides A\u2212I, dimeric or monomeric sesquiterpene lactones from Parthenium hysterophorus L","volume":"219","author":"Li","year":"2024","journal-title":"Phytochemistry"},{"key":"10.1016\/j.phytochem.2025.114734_bib14","doi-asserted-by":"crossref","DOI":"10.1111\/njb.01977","article-title":"Cissampelopsis quinquesquamata (Asteraceae\u2013Senecioneae), a new species from western Myanmar and northeastern India","volume":"36","author":"Li","year":"2018","journal-title":"Nord. J. Bot."},{"key":"10.1016\/j.phytochem.2025.114734_bib15","doi-asserted-by":"crossref","first-page":"3081","DOI":"10.1021\/acs.jnatprod.6b00921","article-title":"Characteristic \u03b1-acid derivatives from Humulus lupulus with antineuroinflammatory activities","volume":"80","author":"Li","year":"2017","journal-title":"J. Nat. Prod."},{"key":"10.1016\/j.phytochem.2025.114734_bib16","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2020.109955","article-title":"Antitumor activity and mechanism of costunolide and dehydrocostus lactone: two natural sesquiterpene lactones from the Asteraceae family","volume":"125","author":"Li","year":"2020","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.phytochem.2025.114734_bib17","first-page":"2835","article-title":"Study on chemical constituents of ethanol extract from Yao medicine Cissampelopsis spelaeicola","volume":"30","author":"Liang","year":"2019","journal-title":"Med. Plants"},{"key":"10.1016\/j.phytochem.2025.114734_bib18","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1021\/np0505061","article-title":"Bisabolane sesquiterpenes from the roots of Ligularia cymbulifera","volume":"69","author":"Liu","year":"2006","journal-title":"J. Nat. Prod."},{"key":"10.1016\/j.phytochem.2025.114734_bib19","doi-asserted-by":"crossref","DOI":"10.1016\/j.phytochem.2025.114509","article-title":"Diterpenoids from Marmoritis complanata and their anti-inflammatory activity in zebrafish","volume":"236","author":"Liu","year":"2025","journal-title":"Phytochemistry"},{"key":"10.1016\/j.phytochem.2025.114734_bib20","doi-asserted-by":"crossref","first-page":"1839","DOI":"10.1021\/cr200106v","article-title":"Computational prediction of 1H and 13C chemical shifts: a useful toolfor natural product, mechanistic, and synthetic organic chemistry","volume":"112","author":"Lodewyk","year":"2012","journal-title":"Chem. Rev."},{"key":"10.1016\/j.phytochem.2025.114734_bib21","doi-asserted-by":"crossref","first-page":"1339","DOI":"10.1007\/s00044-019-02385-7","article-title":"Advance in biological activities of natural guaiane-type sesquiterpenes","volume":"28","author":"Ma","year":"2019","journal-title":"Med. Chem. Res."},{"key":"10.1016\/j.phytochem.2025.114734_bib22","first-page":"90","article-title":"Cytotoxic Compounds from the stem bark of Magnolia obovata","volume":"14","author":"Min","year":"2008","journal-title":"Nat. Prod. Sci."},{"key":"10.1016\/j.phytochem.2025.114734_bib23","volume":"p159","author":"Qin","year":"2022"},{"key":"10.1016\/j.phytochem.2025.114734_bib24","doi-asserted-by":"crossref","DOI":"10.1016\/j.phytochem.2021.112927","article-title":"Bisabolane-type sesquiterpenoids: structural diversity and biological activity","volume":"192","author":"Shu","year":"2021","journal-title":"Phytochemistry"},{"key":"10.1016\/j.phytochem.2025.114734_bib25","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1021\/np030558v","article-title":"New constituents of Artemisia monosperma","volume":"67","author":"Stavri","year":"2004","journal-title":"J. Nat. Prod."},{"key":"10.1016\/j.phytochem.2025.114734_bib26","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.1021\/np0580098","article-title":"Xanthone and sesquiterpene derivatives from the fruits of Garcinia scortechinii","volume":"68","author":"Sukpondma","year":"2005","journal-title":"J. Nat. Prod."},{"key":"10.1016\/j.phytochem.2025.114734_bib27","first-page":"544","article-title":"Insight into chemical composition and anti-inflammatory activities of essential oil from flowers, leaves and Vine stems of Cissampelopsis volubilis Miq","volume":"18","author":"Van Bui","year":"2024","journal-title":"Record Nat. Prod."},{"key":"10.1016\/j.phytochem.2025.114734_bib28","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1039\/c0np00011f","article-title":"Xanthane sesquiterpenoids: structure, synthesis and biological activity","volume":"28","author":"Vasas","year":"2011","journal-title":"Nat. Prod. Rep."},{"key":"10.1016\/j.phytochem.2025.114734_bib29","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/j.carres.2010.11.015","article-title":"Novel steroidal saponins from Liriope graminifolia (Linn.) Baker with anti-tumor activities","volume":"346","author":"Wang","year":"2011","journal-title":"Carbohydr. Res."},{"key":"10.1016\/j.phytochem.2025.114734_bib30","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1021\/acs.jnatprod.1c00947","article-title":"Structures and biological activities of polyacylated ent-kaurane diterpenoid glycosides from the aerial parts of Inula hupehensis","volume":"85","author":"Wang","year":"2022","journal-title":"J. Nat. Prod."},{"key":"10.1016\/j.phytochem.2025.114734_bib31","doi-asserted-by":"crossref","first-page":"4309","DOI":"10.1021\/jo00334a049","article-title":"On some guaiol oxidation products","volume":"46","author":"Winter","year":"1981","journal-title":"J. Org. Chem."},{"key":"10.1016\/j.phytochem.2025.114734_bib32","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1039\/b606168k","article-title":"Eudesmane sesquiterpenoids from the Asteraceae family","volume":"23","author":"Wu","year":"2006","journal-title":"Nat. Prod. Rep."},{"key":"10.1016\/j.phytochem.2025.114734_bib33","doi-asserted-by":"crossref","DOI":"10.1016\/j.bioorg.2020.104597","article-title":"Natural potential neuroinflammatory inhibitors from Stephania epigaea H. S. Lo","volume":"107","author":"Xiao","year":"2021","journal-title":"Bioorg. Chem."},{"key":"10.1016\/j.phytochem.2025.114734_bib34","doi-asserted-by":"crossref","first-page":"2448","DOI":"10.1002\/hlca.201000106","article-title":"Sesquiterpenoids from Senecio argunensis","volume":"93","author":"Xie","year":"2011","journal-title":"Helv. Chim. Acta"},{"key":"10.1016\/j.phytochem.2025.114734_bib35","doi-asserted-by":"crossref","first-page":"5284","DOI":"10.1021\/acs.joc.1c00240","article-title":"Piperhancins A and B, two pairs of antineuroinflammatory cycloneolignane enantiomers from Piper hancei","volume":"86","author":"Yang","year":"2021","journal-title":"J. Org. Chem."},{"key":"10.1016\/j.phytochem.2025.114734_bib36","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.jep.2018.02.025","article-title":"Piper sarmentosum Roxb. confers neuroprotection on beta-amyloid (A\u03b2)-induced microglia-mediated neuroinflammation and attenuates tau hyperphosphorylation in SH-SY5Y cells","volume":"217","author":"Yeo","year":"2018","journal-title":"J. Ethnopharmacol."}],"container-title":["Phytochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0031942225003577?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0031942225003577?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T22:59:36Z","timestamp":1773874776000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0031942225003577"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":36,"alternative-id":["S0031942225003577"],"URL":"https:\/\/doi.org\/10.1016\/j.phytochem.2025.114734","relation":{},"ISSN":["0031-9422"],"issn-type":[{"value":"0031-9422","type":"print"}],"subject":[],"published":{"date-parts":[[2026,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Structurally diverse sesquiterpenoid glycosides with anti-inflammatory activity from Cissampelopsis spelaeicola","name":"articletitle","label":"Article Title"},{"value":"Phytochemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.phytochem.2025.114734","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"114734"}}