{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T01:06:47Z","timestamp":1779239207303,"version":"3.51.4"},"reference-count":50,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100018619","name":"National Program for Support of Top-notch Young Professionals","doi-asserted-by":"publisher","award":["0106514050"],"award-info":[{"award-number":["0106514050"]}],"id":[{"id":"10.13039\/501100018619","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2021YFA0910500"],"award-info":[{"award-number":["2021YFA0910500"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003397","name":"Huazhong University of Science and Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003397","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003819","name":"Natural Science Foundation of Hubei Province","doi-asserted-by":"publisher","award":["2024AFA028"],"award-info":[{"award-number":["2024AFA028"]}],"id":[{"id":"10.13039\/501100003819","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82360695"],"award-info":[{"award-number":["82360695"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82304340"],"award-info":[{"award-number":["82304340"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82273811"],"award-info":[{"award-number":["82273811"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22577033"],"award-info":[{"award-number":["22577033"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Phytochemistry"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1016\/j.phytochem.2026.114891","type":"journal-article","created":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T07:49:36Z","timestamp":1774424976000},"page":"114891","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Undescribed phenylspirodrimane dimers with anti-gouty activity from the coral-derived fungus Stachybotrys chartarum"],"prefix":"10.1016","volume":"248","author":[{"given":"Shuang","family":"Lin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi-Fan","family":"Geng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hanxiao","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zixue","family":"Chai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Baolei","family":"Fan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1458-5383","authenticated-orcid":false,"given":"Jun-Cheng","family":"Su","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yonghui","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhengxi","family":"Hu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.phytochem.2026.114891_bib1","doi-asserted-by":"crossref","DOI":"10.1016\/j.phytochem.2025.114684","article-title":"Bioactive specialized metabolites of Trochila sp., an endophytic fungus of Lilium carniolicum","volume":"242","author":"Alilou","year":"2026","journal-title":"Phytochemistry"},{"key":"10.1016\/j.phytochem.2026.114891_bib2","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1021\/acs.jnatprod.5c01368","article-title":"The role of natural product chemistry in drug discovery: two decades of progress and perspectives","volume":"89","author":"Butler","year":"2026","journal-title":"J. Nat. Prod."},{"key":"10.1016\/j.phytochem.2026.114891_bib3","doi-asserted-by":"crossref","first-page":"1401","DOI":"10.1021\/acs.jnatprod.4c00116","article-title":"Peniditerpenoids A and B: oxidized indole diterpenoids with osteoclast differentiation inhibitory activity from a mangrove-sediment-derived Penicillium sp","volume":"87","author":"Cai","year":"2024","journal-title":"J. Nat. Prod."},{"key":"10.1016\/j.phytochem.2026.114891_bib4","doi-asserted-by":"crossref","first-page":"e197","DOI":"10.1016\/S2665-9913(24)00248-0","article-title":"Cardiovascular events in patients with gout initiating urate-lowering therapy with or without colchicine for flare prophylaxis: a retrospective new-user cohort study using linked primary care, hospitalisation, and mortality data","volume":"7","author":"Cipolletta","year":"2025","journal-title":"Lancet Rheumatol."},{"key":"10.1016\/j.phytochem.2026.114891_bib5","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1038\/s41422-024-01023-1","article-title":"Transport mechanism and structural pharmacology of human urate transporter URAT1","volume":"34","author":"Dai","year":"2024","journal-title":"Cell Res."},{"key":"10.1016\/j.phytochem.2026.114891_bib6","doi-asserted-by":"crossref","first-page":"1843","DOI":"10.1016\/S0140-6736(21)00569-9","volume":"397","author":"Dalbeth","year":"2021","journal-title":"Gout. Lancet"},{"key":"10.1016\/j.phytochem.2026.114891_bib7","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1007\/s40266-017-0461-y","article-title":"Lesinurad: a review in hyperuricaemia of gout","volume":"34","author":"Deeks","year":"2017","journal-title":"Drugs Aging"},{"key":"10.1016\/j.phytochem.2026.114891_bib8","doi-asserted-by":"crossref","first-page":"11744","DOI":"10.1021\/acs.orglett.5c03443","article-title":"Anti-inflammatory Alkaloids, Papaversomni A, a hexacyclic-membered morphinan, and two pairs of E\/Z nonseparable stereoisomers, papaversomni C and sinoracutinal, from Papaver somniferum","volume":"27","author":"Girimpuhwe","year":"2025","journal-title":"Org. Lett."},{"key":"10.1016\/j.phytochem.2026.114891_bib9","doi-asserted-by":"crossref","DOI":"10.1016\/j.phytochem.2025.114494","article-title":"Isolation of pentasaccharide resin glycosides from the whole plants of Ipomoea biflora and their cytotoxic activities","volume":"236","author":"Gu","year":"2025","journal-title":"Phytochemistry"},{"key":"10.1016\/j.phytochem.2026.114891_bib10","first-page":"577","article-title":"Natural products from untapped sources as a potent reserve against antimicrobial resistance crisis","volume":"22","author":"Gu","year":"2024","journal-title":"Chin. J. Nat. Med."},{"key":"10.1016\/j.phytochem.2026.114891_bib11","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1080\/17425255.2023.2287477","article-title":"Overview of the pharmacokinetics and pharmacodynamics of URAT1 inhibitors for the treatment of hyperuricemia and gout","volume":"19","author":"Hou","year":"2023","journal-title":"Expert Opin. Drug Metab. Toxicol."},{"key":"10.1016\/j.phytochem.2026.114891_bib12","doi-asserted-by":"crossref","DOI":"10.1016\/j.phytochem.2025.114713","article-title":"An unprecedented alternariol-zinnol hybrid and six undescribed zinnol derivatives from the phytopathogen Alternaria solani and their cytotoxic activities","volume":"242","author":"Hu","year":"2026","journal-title":"Phytochemistry"},{"key":"10.1016\/j.phytochem.2026.114891_bib13","doi-asserted-by":"crossref","DOI":"10.1016\/j.phytochem.2025.114490","article-title":"Indole alkaloids from Uncaria rhynchophylla and their inhibitory activities against \u03b1-glucosidase","volume":"236","author":"Huang","year":"2025","journal-title":"Phytochemistry"},{"key":"10.1016\/j.phytochem.2026.114891_bib14","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1080\/10286020.2019.1680645","article-title":"Bistachybotrysin K, one new phenylspirodrimane dimer from Stachybotrys chartarum with potent cytotoxic activity","volume":"22","author":"Jia","year":"2020","journal-title":"J. Asian Nat. Prod. Res."},{"key":"10.1016\/j.phytochem.2026.114891_bib15","doi-asserted-by":"crossref","first-page":"748","DOI":"10.3803\/EnM.2024.2020","article-title":"Impact of chronic kidney disease and gout on end-stage renal disease in Type 2 diabetes: population-based cohort study","volume":"39","author":"Jung","year":"2024","journal-title":"Endocrinol. Metab."},{"key":"10.1016\/j.phytochem.2026.114891_bib16","doi-asserted-by":"crossref","DOI":"10.1016\/j.bioorg.2023.107042","article-title":"Pathology, target discovery, and the evolution of XO inhibitors from the first discovery to recent advances (2020\u20132023)","volume":"143","author":"Kumar","year":"2024","journal-title":"Bioorg. Chem."},{"key":"10.1016\/j.phytochem.2026.114891_bib17","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1038\/s41584-024-01137-1","article-title":"The pathogenesis of gout: molecular insights from genetic, epigenomic and transcriptomic studies","volume":"20","author":"Leask","year":"2024","journal-title":"Nat. Rev. Rheumatol."},{"key":"10.1016\/j.phytochem.2026.114891_bib18","doi-asserted-by":"crossref","first-page":"643","DOI":"10.2165\/00002018-200831080-00002","article-title":"A benefit-risk assessment of benzbromarone in the treatment of gout. Was its withdrawal from the market in the best interest of patients?","volume":"31","author":"Lee","year":"2008","journal-title":"Drug Saf."},{"key":"10.1016\/j.phytochem.2026.114891_bib19","doi-asserted-by":"crossref","DOI":"10.1016\/j.bioorg.2025.109012","article-title":"Galactomannan tetrasaccharide targets mannose receptor to suppress hepatocellular carcinoma growth through ROS\/JNK signaling-induced apoptosis and ROS-mediated autophagy-dependent cell death","volume":"165","author":"Li","year":"2025","journal-title":"Bioorg. Chem."},{"key":"10.1016\/j.phytochem.2026.114891_bib20","doi-asserted-by":"crossref","DOI":"10.1016\/j.phytochem.2024.114199","article-title":"Atranones and dolabellanes with cardiomyocyte protective activity against cold ischemic injury from a coral-associated fungus Stachybotrys chartarum","volume":"225","author":"Lin","year":"2024","journal-title":"Phytochemistry"},{"key":"10.1016\/j.phytochem.2026.114891_bib21","doi-asserted-by":"crossref","first-page":"4587","DOI":"10.1016\/j.cclet.2022.03.064","article-title":"Distachydrimanes A\u2013F, phenylspirodrimane dimers and hybrids with cytotoxic activity from the coral-derived fungus Stachybotrys chartarum","volume":"33","author":"Lin","year":"2022","journal-title":"Chin. Chem. Lett."},{"key":"10.1016\/j.phytochem.2026.114891_bib22","doi-asserted-by":"crossref","DOI":"10.1016\/j.bioorg.2021.105091","article-title":"New secondary metabolites with immunosuppressive and BChE inhibitory activities from an endophytic fungus Daldinia sp. TJ403-LS1","volume":"114","author":"Lin","year":"2021","journal-title":"Bioorg. Chem."},{"key":"10.1016\/j.phytochem.2026.114891_bib23","doi-asserted-by":"crossref","first-page":"5435","DOI":"10.1021\/acs.orglett.5c01397","article-title":"Diasperonins A\u2013F: Anti-inflammatory aspertetronin dimers discovered via BBMN and heterologous expression strategy","volume":"27","author":"Lin","year":"2025","journal-title":"Org. Lett."},{"key":"10.1016\/j.phytochem.2026.114891_bib24","doi-asserted-by":"crossref","DOI":"10.3389\/fcvm.2025.1541307","article-title":"A systematic review and network meta-analysis of cardiovascular safety of benzbromarone compared to febuxostat and allopurinol in patients with gout","volume":"12","author":"Lin","year":"2025","journal-title":"Front. Cardiovasc. Med."},{"key":"10.1016\/j.phytochem.2026.114891_bib25","article-title":"Complete biosynthesis of phenylspirodrimanes with unclustered genes in Stachybotrys chartarum","author":"Liu","year":"2025","journal-title":"Acta Pharm. Sin. B"},{"key":"10.1016\/j.phytochem.2026.114891_bib26","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1039\/C9QO01284B","article-title":"Bistachybotrysins L\u2013V, bioactive phenylspirodrimane dimers from the fungus Stachybotrys chartarum","volume":"7","author":"Liu","year":"2020","journal-title":"Org. Chem. Front."},{"key":"10.1016\/j.phytochem.2026.114891_bib27","doi-asserted-by":"crossref","DOI":"10.1016\/j.cclet.2023.108363","article-title":"Structural diversification of phenylspirodrimane lactams by employing a biosynthetic intermediate","volume":"34","author":"Liu","year":"2023","journal-title":"Chin. Chem. Lett."},{"key":"10.1016\/j.phytochem.2026.114891_bib28","doi-asserted-by":"crossref","DOI":"10.1016\/j.phytochem.2025.114704","article-title":"Cytotoxic tetralone homology dimers from mangrove-associated fungus Cytospora heveae NSHSJ-2","volume":"242","author":"Liu","year":"2026","journal-title":"Phytochemistry"},{"key":"10.1016\/j.phytochem.2026.114891_bib29","first-page":"195","article-title":"Progress in approved drugs from natural product resources","volume":"22","author":"Luo","year":"2024","journal-title":"Chin. J. Nat. Med."},{"key":"10.1016\/j.phytochem.2026.114891_bib30","doi-asserted-by":"crossref","DOI":"10.1016\/j.bioorg.2025.109189","article-title":"Isolation and bioactivity evaluation of ten novel norlignans and additional neuroprotective compounds from Curculigo gracilis","author":"Ma","year":"2025","journal-title":"Bioorg. Chem."},{"key":"10.1016\/j.phytochem.2026.114891_bib31","first-page":"504","article-title":"Structurally diverse sesquiterpenoids with anti-MDR cancer activity from Penicillium roqueforti","volume":"23","author":"Mo","year":"2025","journal-title":"Chin. J. Nat. Med."},{"key":"10.1016\/j.phytochem.2026.114891_bib32","doi-asserted-by":"crossref","DOI":"10.1016\/j.phytochem.2023.113722","article-title":"Ten undescribed eremophilane and guaiane sesquiterpenes from Penicillium roqueforti","volume":"212","author":"Mo","year":"2023","journal-title":"Phytochemistry"},{"key":"10.1016\/j.phytochem.2026.114891_bib33","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1021\/acs.jnatprod.9b01285","article-title":"Natural products as sources of new drugs over the nearly four decades from 01\/1981 to 09\/2019","volume":"83","author":"Newman","year":"2020","journal-title":"J. Nat. Prod."},{"key":"10.1016\/j.phytochem.2026.114891_bib34","doi-asserted-by":"crossref","first-page":"241","DOI":"10.4078\/jrd.2024.0121","article-title":"Association between serum urate, gout and chronic kidney disease: a scoping review of systematic reviews and meta-analyses","volume":"32","author":"Oh","year":"2025","journal-title":"J. Rheum. Dis."},{"key":"10.1016\/j.phytochem.2026.114891_bib35","first-page":"346","article-title":"Ustusolate E and 11\u03b1-Hydroxy-Ustusolate E induce apoptosis in cancer cell lines by regulating the PI3K\/AKT\/mTOR and p-53 pathways","volume":"23","author":"Rehmutulla","year":"2025","journal-title":"Chin. J. Nat. Med."},{"key":"10.1016\/j.phytochem.2026.114891_bib36","doi-asserted-by":"crossref","first-page":"1174","DOI":"10.1093\/eurheartj\/ehi879","article-title":"Uric acid and inflammatory markers","volume":"27","author":"Ruggiero","year":"2006","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.phytochem.2026.114891_bib37","doi-asserted-by":"crossref","DOI":"10.1016\/j.phytochem.2023.113836","article-title":"Linderanidins A\u2013F: rare oligomeric flavonoids with an unusual C-3\u2013C-4 linkage from the roots of Lindera erythrocarpa and their inhibitory activities on autophagy","volume":"215","author":"Ryu","year":"2023","journal-title":"Phytochemistry"},{"key":"10.1016\/j.phytochem.2026.114891_bib38","doi-asserted-by":"crossref","first-page":"16825","DOI":"10.1021\/acs.jafc.4c04764","article-title":"Stimulating novel and bioactive metabolite production by cocultivation of two fungi\u2013Aspergillus oryzae and Epicoccum dendrobii","volume":"72","author":"Shen","year":"2024","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.phytochem.2026.114891_bib39","doi-asserted-by":"crossref","first-page":"19966","DOI":"10.1021\/acs.jmedchem.4c01260","article-title":"Recent progress and future perspectives on anti-hyperuricemic agents","volume":"67","author":"Sun","year":"2024","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.phytochem.2026.114891_bib40","doi-asserted-by":"crossref","DOI":"10.1016\/j.bioorg.2024.107716","article-title":"Identification of O-arylated huperzinines as novel cholinergic anti-inflammatory pathway agonists against gout arthritis","volume":"152","author":"Wu","year":"2024","journal-title":"Bioorg. Chem."},{"key":"10.1016\/j.phytochem.2026.114891_bib41","doi-asserted-by":"crossref","first-page":"3310","DOI":"10.1038\/s41598-025-86090-z","article-title":"A comprehensive analysis of trends in the burden of gout in China and globally from 1990 to 2021","volume":"15","author":"Xie","year":"2025","journal-title":"Sci. Rep."},{"key":"10.1016\/j.phytochem.2026.114891_bib42","doi-asserted-by":"crossref","first-page":"12177","DOI":"10.1021\/acs.jafc.3c00346","article-title":"Purple yam polyphenol extracts exert anticolitis and anticolitis-associated colorectal cancer effects through inactivation of NF-\u03baB\/p65 and STAT3 signaling pathways","volume":"71","author":"Yang","year":"2023","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.phytochem.2026.114891_bib43","doi-asserted-by":"crossref","first-page":"3082","DOI":"10.7150\/thno.95611","article-title":"Well-defined alginate oligosaccharides ameliorate joint pain and inflammation in a mouse model of gouty arthritis","volume":"14","author":"Yin","year":"2024","journal-title":"Theranostics"},{"key":"10.1016\/j.phytochem.2026.114891_bib44","doi-asserted-by":"crossref","DOI":"10.1016\/j.bioorg.2024.107175","article-title":"Anti-necroptosis and anti-ferroptosis compounds from the deep-sea-derived fungus Aspergillus sp. MCCC 3A00392","volume":"144","author":"Yu","year":"2024","journal-title":"Bioorg. Chem."},{"key":"10.1016\/j.phytochem.2026.114891_bib45","doi-asserted-by":"crossref","first-page":"3520","DOI":"10.1039\/C8RA10195G","article-title":"Seven new cytotoxic phenylspirodrimane derivatives from the endophytic fungus Stachybotrys chartarum","volume":"9","author":"Zhang","year":"2019","journal-title":"RSC Adv."},{"key":"10.1016\/j.phytochem.2026.114891_bib46","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/j.cclet.2018.04.031","article-title":"Bistachybotrysins D and E, one stereoisomeric pair of cytotoxic phenylspirodrimane dimers from Stachybotrys chartarum","volume":"30","author":"Zhang","year":"2019","journal-title":"Chin. Chem. Lett."},{"key":"10.1016\/j.phytochem.2026.114891_bib47","doi-asserted-by":"crossref","DOI":"10.1016\/j.phytochem.2025.114481","article-title":"Andrograpalides A\u2013N, structurally diverse ent-labdane diterpenoids with anti-inflammatory activities from the leaves of Andrographis paniculata","volume":"236","author":"Zhang","year":"2025","journal-title":"Phytochemistry"},{"key":"10.1016\/j.phytochem.2026.114891_bib48","doi-asserted-by":"crossref","DOI":"10.1016\/j.bioorg.2025.109002","article-title":"Exploring the mechanism of Levistolide A in the treatment of lung cancer cells based on network analysis, molecular docking and experimental validation","volume":"165","author":"Zhao","year":"2025","journal-title":"Bioorg. Chem."},{"key":"10.1016\/j.phytochem.2026.114891_bib49","doi-asserted-by":"crossref","first-page":"12006","DOI":"10.1021\/acs.orglett.5c03641","article-title":"HPLC\u2013UV-Guided Discovery of Eurotamines A\u2013F: six pairs of isoquinoline derivative enantiomers from marine-derived fungus Eurotium sp. SCSIO F452","volume":"27","author":"Zhong","year":"2025","journal-title":"Org. Lett."},{"key":"10.1016\/j.phytochem.2026.114891_bib50","doi-asserted-by":"crossref","DOI":"10.1016\/j.bioorg.2024.107558","article-title":"Structure-activity relationships of natural and synthetic lathyrane-based diterpenoids for suppression of NLRP3-driven inflammation and gouty arthritis","volume":"150","author":"Zhuang","year":"2024","journal-title":"Bioorg. Chem."}],"container-title":["Phytochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S003194222600124X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S003194222600124X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T00:23:18Z","timestamp":1779236598000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S003194222600124X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":50,"alternative-id":["S003194222600124X"],"URL":"https:\/\/doi.org\/10.1016\/j.phytochem.2026.114891","relation":{},"ISSN":["0031-9422"],"issn-type":[{"value":"0031-9422","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Undescribed phenylspirodrimane dimers with anti-gouty activity from the coral-derived fungus Stachybotrys chartarum","name":"articletitle","label":"Article Title"},{"value":"Phytochemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.phytochem.2026.114891","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"114891"}}