{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T19:57:03Z","timestamp":1781639823750,"version":"3.54.5"},"reference-count":16,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T00:00:00Z","timestamp":1773360000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Practical Laboratory Medicine"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1016\/j.plabm.2026.e00527","type":"journal-article","created":{"date-parts":[[2026,3,15]],"date-time":"2026-03-15T15:54:34Z","timestamp":1773590074000},"page":"e00527","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Biochemical deciphering of an Atypical methemoglobinemia"],"prefix":"10.1016","volume":"50","author":[{"given":"Antonin","family":"Lucbert","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H\u00e9l\u00e8ne","family":"Caillon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre-Olivier","family":"Bertho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Damien","family":"Masson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9191-4665","authenticated-orcid":false,"given":"Manon","family":"Robert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.plabm.2026.e00527_bib1","article-title":"Acquired methemoglobinemia: a systematic review of reported cases","volume":"61","author":"Gao","year":"2022","journal-title":"Transfus. Apher. Sci.: Official Journal of the World Apheresis Association: Official Journal of the European Society for Haemapheresis"},{"key":"10.1016\/j.plabm.2026.e00527_bib2","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1016\/S0196-0644(99)70167-8","article-title":"Methemoglobinemia: etiology, pharmacology, and clinical management","volume":"34","author":"Wright","year":"1999","journal-title":"Ann. Emerg. Med."},{"key":"10.1016\/j.plabm.2026.e00527_bib3","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1002\/ajh.20738","article-title":"Methemoglobin--it\u2019s not just blue: a concise review","volume":"82","author":"Umbreit","year":"2007","journal-title":"Am. J. Hematol."},{"key":"10.1016\/j.plabm.2026.e00527_bib4","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1177\/000992289703600410","article-title":"Methemoglobinemia associated with a prilocaine-lidocaine cream","volume":"36","author":"Kumar","year":"1997","journal-title":"Clin. Pediatr."},{"key":"10.1016\/j.plabm.2026.e00527_bib5","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1097\/SMJ.0b013e318232139f","article-title":"Methemoglobinemia: pathogenesis, diagnosis, and management","volume":"104","author":"Skold","year":"2011","journal-title":"South. Med. J."},{"key":"10.1016\/j.plabm.2026.e00527_bib6","doi-asserted-by":"crossref","DOI":"10.1164\/rccm.201806-1044IM","article-title":"Poppers-induced life-threatening methemoglobinemia","volume":"198","author":"Lefevre","year":"2018","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.plabm.2026.e00527_bib7","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.arcped.2016.10.013","article-title":"[food protein-induced enterocolitis syndrome: a case report of diarrhea with hypovolemic shock and methemoglobinemia]","volume":"24","author":"Genere","year":"2017","journal-title":"Arch. Pediatr.: Organe Officiel De La Societe Francaise De Pediatrie"},{"key":"10.1016\/j.plabm.2026.e00527_bib8","doi-asserted-by":"crossref","first-page":"3870","DOI":"10.1073\/pnas.70.12.3870","article-title":"Structure of hemoglobin M Boston, a variant with a five-coordinated ferric heme","volume":"70","author":"Pulsinelli","year":"1973","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.plabm.2026.e00527_bib9","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/j.hoc.2015.11.006","article-title":"Glucose-6-Phosphate dehydrogenase deficiency","volume":"30","author":"Luzzatto","year":"2016","journal-title":"Hematol. Oncol. Clin. N. Am."},{"key":"10.1016\/j.plabm.2026.e00527_bib10","doi-asserted-by":"crossref","first-page":"3399","DOI":"10.1007\/s00277-023-05364-6","article-title":"Rasburicase-induced hemolytic anemia and methemoglobinemia: a systematic review of current reports","volume":"103","author":"Hammami","year":"2024","journal-title":"Ann. Hematol."},{"key":"10.1016\/j.plabm.2026.e00527_bib11","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/S0140-6736(08)60073-2","article-title":"Glucose-6-phosphate dehydrogenase deficiency","volume":"371","author":"Cappellini","year":"2008","journal-title":"Lancet"},{"key":"10.1016\/j.plabm.2026.e00527_bib12","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1177\/1078155217701295","article-title":"Rasburicase-induced methemoglobinemia: the eyes do not see what the mind does not know","volume":"24","author":"Ibrahim","year":"2018","journal-title":"J. Oncol. Pharm. Pract.: Official Publication of the International Society of Oncology Pharmacy Practitioners"},{"key":"10.1016\/j.plabm.2026.e00527_bib13","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.rmcr.2018.12.011","article-title":"Rasburicase induced severe hemolysis and methemoglobinemia in a Caucasian patient complicated by acute renal failure and ARDS","volume":"26","author":"Raru","year":"2019","journal-title":"Respiratory Medicine Case Reports"},{"key":"10.1016\/j.plabm.2026.e00527_bib14","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.1177\/10781552221075239","article-title":"Rasburicase induced methemoglobinemia: a systematic review of descriptive studies","volume":"28","author":"Vidhyashree","year":"2022","journal-title":"J. Oncol. Pharm. Pract.: Official Publication of the International Society of Oncology Pharmacy Practitioners"},{"key":"10.1016\/j.plabm.2026.e00527_bib15","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1002\/ccr3.495","article-title":"Rasburicase-induced methemoglobinemia: case report, literature review, and proposed treatment algorithm","volume":"4","author":"Sherwood","year":"2016","journal-title":"Clin. Case Rep."},{"key":"10.1016\/j.plabm.2026.e00527_bib16","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1373\/clinchem.2004.035154","article-title":"Laboratory assessment of oxygenation in methemoglobinemia","volume":"51","author":"Haymond","year":"2005","journal-title":"Clin. Chem."}],"container-title":["Practical Laboratory Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352551726000090?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352551726000090?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T19:36:24Z","timestamp":1781638584000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2352551726000090"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":16,"alternative-id":["S2352551726000090"],"URL":"https:\/\/doi.org\/10.1016\/j.plabm.2026.e00527","relation":{},"ISSN":["2352-5517"],"issn-type":[{"value":"2352-5517","type":"print"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Biochemical deciphering of an Atypical methemoglobinemia","name":"articletitle","label":"Article Title"},{"value":"Practical Laboratory Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.plabm.2026.e00527","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"e00527"}}