{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T06:18:39Z","timestamp":1789625919334,"version":"build-2803163510"},"reference-count":43,"publisher":"Elsevier BV","issue":"2-3","license":[{"start":{"date-parts":[[2007,2,1]],"date-time":"2007-02-01T00:00:00Z","timestamp":1170288000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2007,2,1]],"date-time":"2007-02-01T00:00:00Z","timestamp":1170288000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Placenta"],"published-print":{"date-parts":[[2007,2]]},"DOI":"10.1016\/j.placenta.2006.02.002","type":"journal-article","created":{"date-parts":[[2006,3,31]],"date-time":"2006-03-31T07:14:54Z","timestamp":1143789294000},"page":"85-96","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"title":["Carcinoembryonic Antigen and Related Molecules in Normal and Transformed Trophoblast"],"prefix":"10.1016","volume":"28","author":[{"given":"Lj.","family":"Vi\u0107ovac","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Bo\u017ei\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u017d.","family":"Boji\u0107-Trbojevi\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Golubovi\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.placenta.2006.02.002_bib1","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1128\/MCB.23.1.272-279.2003","article-title":"Carcinoembryonic antigen-related cell adhesion molecule 10 expressed specifically early in pregnancy in the decidua is dispensable for normal murine development","volume":"23","author":"Finkenzeller","year":"2003","journal-title":"Mol Cell Biol"},{"key":"10.1016\/j.placenta.2006.02.002_bib2","first-page":"177","article-title":"The structure, metabolism and function of the carcinoembryonic antigen gene family","volume":"1032","author":"Thomas","year":"1990","journal-title":"Biochim Biophys Acta"},{"key":"10.1016\/j.placenta.2006.02.002_bib3","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1007\/s004030050336","article-title":"The glycoprotein of the carcinoembryonic antigen (CEA) gene family expressed on epithelial keratinocytes in viral warts","volume":"290","author":"Egawa","year":"1998","journal-title":"Arch Dermatol Res"},{"key":"10.1016\/j.placenta.2006.02.002_bib4","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1006\/excr.1999.4610","article-title":"Redefined nomenclature for members of the carcinoembryonic antigen family","volume":"252","author":"Beauchemin","year":"1999","journal-title":"Exp Cell Res"},{"key":"10.1016\/j.placenta.2006.02.002_bib5","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1006\/geno.1994.1555","article-title":"Gene organization of the pregnancy-specific glycoprotein region on human chromosome 19: assembly and analysis of a 700-kb cosmid contig spanning the region","volume":"23","author":"Olsen","year":"1994","journal-title":"Genomics"},{"key":"10.1016\/j.placenta.2006.02.002_bib6","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1016\/S0955-0674(97)80114-7","article-title":"CEA adhesion molecules: multifunctional proteins with signal-regulatory properties","volume":"9","author":"\u00d6brink","year":"1997","journal-title":"Curr Opin Cell Biol"},{"key":"10.1016\/j.placenta.2006.02.002_bib7","doi-asserted-by":"crossref","first-page":"7140","DOI":"10.1128\/MCB.20.19.7140-7145.2000","article-title":"Trophoblast cell-specific carcinoembryonic antigen cell adhesion molecule 9 is not required for placental development or a positive outcome of allotypic pregnancies","volume":"20","author":"Finkenzeller","year":"2000","journal-title":"Mol Cell Biol"},{"key":"10.1016\/j.placenta.2006.02.002_bib8","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1002\/jcla.1860050510","article-title":"Carcinoembryonic antigen gene family: molecular biology and clinical perspectives","volume":"5","author":"Thompson","year":"1991","journal-title":"J Clin Lab Anal"},{"key":"10.1016\/j.placenta.2006.02.002_bib9","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1159\/000217923","article-title":"Molecular cloning and expression of carcinoembryonic antigen gene family members","volume":"16","author":"Thompson","year":"1995","journal-title":"Tumor Biol"},{"key":"10.1016\/j.placenta.2006.02.002_bib10","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1016\/0143-4004(77)90002-9","article-title":"Highly specific monoclonal antibody demonstrates that pregnancy-specific glycoprotein (PSG) is limited to syncytiotrophoblast in human early and term placenta","volume":"18","author":"Zhou","year":"1997","journal-title":"Placenta"},{"key":"10.1016\/j.placenta.2006.02.002_bib11","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1210\/mend-3-1-89","article-title":"Characterization of pregnancy-specific \u03b21-glycoprotein synthesized by human placental fibroblasts","volume":"3","author":"Chou","year":"1989","journal-title":"Mol Endocrinol"},{"key":"10.1016\/j.placenta.2006.02.002_bib12","series-title":"Pathology of the human placenta","first-page":"171","article-title":"Nonvillous parts and trophoblast invasion","author":"Frank","year":"2000"},{"key":"10.1016\/j.placenta.2006.02.002_bib13","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1016\/S0002-9440(10)64985-1","article-title":"The adhesion molecule CEACAM1 (CD66a, C-CAM, BGP) is specifically expressed by the extravillous intermediate trophoblast","volume":"156","author":"Bamberger","year":"2000","journal-title":"Am J Pathol"},{"key":"10.1016\/j.placenta.2006.02.002_bib14","doi-asserted-by":"crossref","DOI":"10.1210\/jc.2004-2434","article-title":"Osteopontin (OPN) is colocalized with the adhesion molecule CEACAM1 in the extravillous trophoblast of the human placenta and enhances invasion of CEACAM1-expressing placental cells","author":"Briese","year":"2005","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.placenta.2006.02.002_bib15","series-title":"Pathology of the human placenta","first-page":"754","article-title":"Trophoblastic neoplasm","author":"Benirschke","year":"2000"},{"key":"10.1016\/j.placenta.2006.02.002_bib16","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1097\/00004347-200104000-00008","article-title":"Expression pattern of the adhesion molecule CEACAM1 (C-CAM, CD66a, BGP) in gestational trophoblast lesions","volume":"20","author":"Bamberger","year":"2001","journal-title":"Int J Gynecol Pathol"},{"key":"10.1016\/j.placenta.2006.02.002_bib17","doi-asserted-by":"crossref","first-page":"5822","DOI":"10.1073\/pnas.87.15.5822","article-title":"Linkage of two human pregnancy specific b1 glycoprotein genes: one is associated with hydatiform mole","volume":"87","author":"Leslie","year":"1990","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.placenta.2006.02.002_bib18","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1006\/scbi.1998.0119","article-title":"The carcinoembryonic antigen (CEA) family: structures, suggested functions and expression in normal and malignant tissues","volume":"9","author":"Hammarstrom","year":"1999","journal-title":"Semin Cancer Biol"},{"key":"10.1016\/j.placenta.2006.02.002_bib19","unstructured":"Golubovi\u0107 S. Immunometric and lectin assays for quantitation and determination of tumor markers chorionic gonadotropin and carcinoembryonic antigen. M.Sc. thesis. University of Belgrade; 1996."},{"key":"10.1016\/j.placenta.2006.02.002_bib20","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1016\/j.placenta.2004.03.006","article-title":"Galectin-1 and galectin-3 in the trophoblast of the gestational trophoblastic disease","volume":"25","author":"Bo\u017ei\u0107","year":"2004","journal-title":"Placenta"},{"key":"10.1016\/j.placenta.2006.02.002_bib21","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1038\/227680a0","article-title":"Cleveage of structural proteins during the assembly of the head of the bacteriophage T4","volume":"227","author":"Laemli","year":"1970","journal-title":"Nature"},{"key":"10.1016\/j.placenta.2006.02.002_bib22","doi-asserted-by":"crossref","first-page":"1032","DOI":"10.1002\/elps.1150121207","article-title":"Sodium dodecyl sulphate-polyacrylamide electrophoresis of human parotid salivary proteins","volume":"12","author":"Beeley","year":"1991","journal-title":"Electrophoresis"},{"key":"10.1016\/j.placenta.2006.02.002_bib23","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1159\/000401157","article-title":"A new placental protein test for the presence and identification of trophoblast tumors","volume":"22","author":"Tatarinov","year":"1978","journal-title":"Antibiot Chemother"},{"key":"10.1016\/j.placenta.2006.02.002_bib24","series-title":"Protein methods","first-page":"181","article-title":"Immunoblotting","author":"Bollag","year":"1991"},{"key":"10.1016\/j.placenta.2006.02.002_bib25","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1152\/physiolgenomics.2001.6.2.105","article-title":"Microarray analysis of trophoblast differentiation: gene expression reprogramming in key gene function categories","volume":"6","author":"Aronow","year":"2001","journal-title":"Physiol Genomics"},{"key":"10.1016\/j.placenta.2006.02.002_bib26","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1038\/sj.neo.7900201","article-title":"Deregulated expression of the human tumor marker CEA and CEA family member CEACAM6 disrupts tissue architecture and blocks colonocyte differentiation","volume":"4","author":"Ilantzis","year":"2002","journal-title":"Neoplasia"},{"key":"10.1016\/j.placenta.2006.02.002_bib27","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1038\/sj.onc.1207036","article-title":"CEACAM6 gene silence impairs anoikis resistance and in vivo metastatic ability of pancreatic adenocarcinoma cells","volume":"15","author":"Duxbury","year":"2004","journal-title":"Oncogene"},{"key":"10.1016\/j.placenta.2006.02.002_bib28","first-page":"3419","article-title":"Human carcinoembryonic antigen functions as general inhibitor of anoikis","volume":"60","author":"Ordonez","year":"2000","journal-title":"Cancer Res"},{"key":"10.1016\/j.placenta.2006.02.002_bib29","doi-asserted-by":"crossref","first-page":"2051","DOI":"10.1128\/iai.59.6.2051-2057.1991","article-title":"Binding of Escherichia coli and Salmonella strains to member of the carcinoembryonic antigen family: differential binding inhibition by aromatic alpha-glycosydes of mannose","volume":"59","author":"Leusch","year":"1991","journal-title":"Infect Immun"},{"key":"10.1016\/j.placenta.2006.02.002_bib30","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1046\/j.1365-2958.1996.01551.x","article-title":"Carcinoembryonic antigens (CD66) on epithelial cells and neutrophils are receptors for Opa proteins of pathogenic neisseriae","volume":"22","author":"Virji","year":"1996","journal-title":"Mol Microbiol"},{"key":"10.1016\/j.placenta.2006.02.002_bib31","doi-asserted-by":"crossref","first-page":"3601","DOI":"10.1128\/IAI.68.6.3601-3607.2000","article-title":"Carcinoembryonic antigen family receptor specificity of Neisseria meningitidis Opa variants influences adherence to and invasion of proinflamatory cytokine-activated endothelial cells","volume":"68","author":"Muenzner","year":"2000","journal-title":"Infect Immun"},{"key":"10.1016\/j.placenta.2006.02.002_bib32","first-page":"43","article-title":"Pregnancy specific beta 1 glycoprotein in fetal and maternal compartments","volume":"52","author":"Grudzinska","year":"1978","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.placenta.2006.02.002_bib33","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1016\/S0006-291X(88)80103-7","article-title":"Human pregnancy-specific \u03b21-glycoprotein: a new member of the carcinoembryonic antigen gene family","volume":"152","author":"Watanabe","year":"1988","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.placenta.2006.02.002_bib34","first-page":"453","article-title":"Within-subject variation of carcinoembryonic antigen in colorectal cancer-application of reference change values and individual reference change values and individual reference ranges to patient follow-up","volume":"35","author":"Mora","year":"1997","journal-title":"Eur J Chem Clin Biochem"},{"key":"10.1016\/j.placenta.2006.02.002_bib35","first-page":"1382","article-title":"High serum carcinoembryonic antigen concentration in patients with colorectal liver metastases is associated with poor cell-mediated immunity, which is predictive of survival","volume":"84","author":"King","year":"1997","journal-title":"Br J Surg"},{"key":"10.1016\/j.placenta.2006.02.002_bib36","first-page":"559","article-title":"The utility of monitoring carcinoembryonic antigen during systemic therapy for advanced colorectal cancer","volume":"5","author":"Grem","year":"1998","journal-title":"Oncol Rep"},{"key":"10.1016\/j.placenta.2006.02.002_bib37","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1002\/1096-9098(200007)74:3<185::AID-JSO4>3.0.CO;2-0","article-title":"Significance of serum and tissue carcinoembryonic antigen for the prognosis of gastric carcinoma patients","volume":"74","author":"Kim","year":"2000","journal-title":"J Surg Oncol"},{"key":"10.1016\/j.placenta.2006.02.002_bib38","first-page":"2191","article-title":"Carcinoembryonic antigen and other glycoconjugates act as ligands for galectin-3 in human colon carcinoma cells","volume":"55","author":"Ohannesian","year":"1995","journal-title":"Cancer Res"},{"key":"10.1016\/j.placenta.2006.02.002_bib39","series-title":"Glycosciences status and perspectives","first-page":"459","article-title":"Galectins in tumor cells","author":"Ohannesian","year":"1997"},{"key":"10.1016\/j.placenta.2006.02.002_bib40","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1046\/j.1365-2559.2000.00988.x","article-title":"Galectin-3 and carcinoembryonic antigen expression in medullary thyroid carcinoma: possible relation to tumour progression","volume":"37","author":"Cvejic","year":"2000","journal-title":"Histopathology"},{"key":"10.1016\/j.placenta.2006.02.002_bib41","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/0002-9378(75)90631-6","article-title":"Carcinoembryonic antigen in patients with gynecologic malignancies","volume":"121","author":"DiSaia","year":"1975","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.placenta.2006.02.002_bib42","doi-asserted-by":"crossref","first-page":"798","DOI":"10.1038\/29563","article-title":"GPI-anchored proteins are organized in submicron domains at the cell surface","volume":"394","author":"Varma","year":"1998","journal-title":"Nature"},{"key":"10.1016\/j.placenta.2006.02.002_bib43","first-page":"3419","article-title":"Human carcinoembryonic antigen functions as a general inhibitor of anoikis","volume":"60","author":"Ordonez","year":"2000","journal-title":"Cancer Res"}],"container-title":["Placenta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0143400406000324?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0143400406000324?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T17:37:51Z","timestamp":1758908271000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0143400406000324"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,2]]},"references-count":43,"journal-issue":{"issue":"2-3","published-print":{"date-parts":[[2007,2]]}},"alternative-id":["S0143400406000324"],"URL":"https:\/\/doi.org\/10.1016\/j.placenta.2006.02.002","relation":{},"ISSN":["0143-4004"],"issn-type":[{"value":"0143-4004","type":"print"}],"subject":[],"published":{"date-parts":[[2007,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Carcinoembryonic Antigen and Related Molecules in Normal and Transformed Trophoblast","name":"articletitle","label":"Article Title"},{"value":"Placenta","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.placenta.2006.02.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2006 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}